Advanced Functional Nanomaterials: Application for Health, Environment and Biosensing

In various health applications, nanoparticles such as liposomes, dendrimers, and metallic nanoparticles play an important role in targeted drug delivery to specific cells, such as cancer cells, and help in crossing the blood barriers for neurological drugs. Quantum dots and gold nanoparticle-based nanoparticles have theragnostic applications in imaging and treating incurable diseases. Similarly, nanomaterials enhance biosensors' sensitivity and can improve biosensors' performance in diagnostic processes. The various graphene, gold, and magnetic nanomaterials could be used in assays for detecting biomarkers, such as wearable devices for real-time monitoring of drug levels/metabolites in the body and biosensing for pharmacodynamic studies or therapeutic drug monitoring. Future trends could involve artificial intelligence (AI) designing nanomaterials or hybrid materials combining different nanoparticles for multifunctional uses. AI has the potential to optimize nanoparticles for targeted drug delivery, tailor nanomaterials for personalized medicine, and deliver multiple drug designs in combination therapies.

The primary goal of this proposal is to explore the potential of advanced nanomaterials in the controlled and sustainable release of drugs to improve therapeutic consistency. Advanced studies related to nanomaterial-based targeted delivery of drugs, especially to disease cells/tissues (e.g., tumors), to minimize damage to healthy cells are aimed to document. Besides, recent advancements in nanomaterials applications to overcome drug resistance, improve bioavailability and solubility, reduce systemic toxicity, and enable personalized and precision medicine are expected to be explored. It is also expected to explore the potential of AI in advanced nanomaterial-based advanced diagnostic and early detection using advanced biosensors. In addition, it is expected to address the environmental and sustainability challenges related to nanomaterials applications in pharmacology.

Scope of the Research Topic:

• Functionalized nanoparticles selectively drugs delivery to targeted diseased cells and controlled release, and overcoming biological barriers using selective nanomaterials

• Nanomaterials enable rapid, sensitive, and cost-effective detection of diseases and biomarkers for effective diagnostics and biosensing

• Tailored therapies through nanocarriers designed using patient-specific biomarkers

• Applications of nanomaterials in regenerative medicine and tissue engineering

• Nanomaterial-based platforms (e.g., lab-on-a-chip) to accelerate drug candidate evaluation and high-throughput screening

• Recent research work on emerging frontiers having nanomaterials applications in gene therapy, neuromodulations, and cancer immunotherapy.

• Application of AI in following fields but not limited: a) Artificial Intelligence (AI) in Designing Nanomaterials for Pharmacology Applications b) AI-Driven Design of Nanomaterials c) AI-Optimized Nanoparticles for targeted drug delivery systems d) AI integrates genomic, proteomic, and clinical data to tailor nanomaterial-drug combinations for individual patients.

Article types and fees

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• Brief Research Report
• Case Report
• Clinical Trial
• Editorial
• FAIR² Data
• FAIR² DATA Direct Submission
• General Commentary
• Hypothesis and Theory
• Methods
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Article types

This Research Topic accepts the following article types, unless otherwise specified in the Research Topic description:

• Brief Research Report
• Case Report
• Clinical Trial
• Editorial
• FAIR² Data
• FAIR² DATA Direct Submission
• General Commentary
• Hypothesis and Theory
• Methods
• Mini Review
• Opinion
• Original Research
• Perspective
• Review
• Technology and Code

Keywords: nanoparticles, targeted drug delivery, biosensors, theranostics, personalized medicine, artificial intelligence, controlled drug release, tumor targeting, gene therapy, precision medicine

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