Discriminating Active Tuberculosis from Latent Tuberculosis Infection: Immunological Characteristics, Biomarkers, and Novel Approaches Volume II

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ORIGINAL RESEARCH

Published on 06 Aug 2026

Machine learning-based feature selection suggests circulating proteins as best at predicting and diagnosing tuberculosis in Mycobacterium tuberculosis-exposed rhesus macaques

Taylor A. L. Woodard
Smriti Mehra
Deepak Kaushal
Vitaly V. Ganusov

doi 10.3389/fcimb.2026.1880496

420 views

ORIGINAL RESEARCH

Published on 02 Jul 2026

Application of metagenomic next-generation sequencing in HIV-negative hematogenous disseminated tuberculosis

Lingxin Luo
Jvrong Zhan
Zhen Wang
Xianzhi Du
Na Li

doi 10.3389/fcimb.2026.1851741

504 views

REVIEW

Published on 19 Jun 2026

Harnessing the gut microbiome to combat tuberculosis: a technological and clinical review

Weiguo Sun
Meng Xiao
Syed Luqman Ali
Chanyuan Jin
Asifullah Khan
Shakirullah
Ruizi Ni
Yajing An
Mingming Zhang
3 more
Wenping Gong

doi 10.3389/fcimb.2026.1847443

1,103 views

ORIGINAL RESEARCH

Published on 09 Jun 2026

Construction and verification of early diagnosis model of tuberculous meningitis

Haoyue Hu
Minzhe Lang
Mingming Zhao
Wenwen Li
Shaoce Zhi
Peng Liu
Guangliang Hong

doi 10.3389/fcimb.2026.1829445

613 views

BRIEF RESEARCH REPORT

Published on 29 May 2026

Endothelial, cytokine, and Th1/cellular host biomarkers discriminate complicated osteoarticular tuberculosis: a prospective single-center cohort study with ROC analysis

Shuhrat Bozorov
Bakhtiyor Khamdamov
Isomiddin Usmanov
Nigora Faizullaeva
Musharraf Shodiyeva

doi 10.3389/fcimb.2026.1866153

1,817 views

ORIGINAL RESEARCH

Published on 01 May 2026

Multiparameter antigen-specific immunoprofiling in subjects with negative IGRA and TST results with potential M. tuberculosis exposures

Balaji Pathakumari
Luis E. Gutierrez
Shaji Ahmed Faisal
Pedro Arias Sanchez
Kale Daniel
Virginia P. Van Keulen
Heather R. Hilgart
Manik R. Reddy
Elitza Theel
4 more
Patricio Escalante

doi 10.3389/fcimb.2026.1837269

1,169 views

ORIGINAL RESEARCH

Published on 04 Feb 2026

Machine learning prediction of pharmacist intervention benefit in tuberculosis patients using clinical parameters: a single-center retrospective study

Tingting Li
Huanqing Liu
Zhuhong You
Qian Lei

doi 10.3389/fcimb.2026.1749499

852 views
1 citation

ORIGINAL RESEARCH

Published on 07 Jan 2026

EBUS-TBNA needle rinse fluid: a superior specimen for the molecular diagnosis of intrathoracic lymph node tuberculosis

Yayan Niu
Xiaohong Li
Jin yu Yan
Huafeng Song
Lin Yao
Lijuan Zhang
Meiying Wu
Peijun Tang
Junchi Xu
Yanjun Feng

doi 10.3389/fcimb.2025.1734956

1,732 views

ORIGINAL RESEARCH

Published on 19 Dec 2025

Effect of PPD inoculation on serum cytokine profiles in latent tuberculosis infection populations

Wenjing Chang
Dingyong Sun
Yanqiu Zhang
Shaoping Ji
Shaohua Wang
Weidong Wang
Xiaoguang Ma
Danwei Zheng
Ruyue Su
2 more
Linqi Diao

doi 10.3389/fcimb.2025.1731603

1,791 views

ORIGINAL RESEARCH

Published on 18 Dec 2025

Validation and interpretation of machine-learning models for rapid identification of active tuberculosis infection using routine laboratory indicators

Zhan-Zhong Liu
Quan Yuan
Yu-Dong Zhang
Xue-Di Zhang
Jian Liu
Jia-Wei Yan
Kang-Peng Du
Hui-Jin Chen
Liang Wang

doi 10.3389/fcimb.2025.1718614

2,693 views

ORIGINAL RESEARCH

Accepted on 30 Jul 2026

Diagnostic Performance of Metagenomic Next-Generation Sequencing in Mycobacterium and non-Mycobacterium infection Patients: A Retrospective Study at a Large Comprehensive Medical Center

Aibo Liu
Shengkun Peng
Rui Tan
Jiaqiang Wang
Honghua Hu
Kai Zhang
Xiaoli Zhou

131 views

ORIGINAL RESEARCH

Accepted on 03 Aug 2026

Immune-Inflammatory Profiles and Disease Severity in Pulmonary Tuberculosis Complicated by Central Nervous System Tuberculosis

Muxing Chen
Di Wu
Xiaohong Chen
Jiandong Lin
Youfei Lin
Hongru Li

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Clinical and Diagnostic Microbiology and Immunology

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Articles

Machine learning-based feature selection suggests circulating proteins as best at predicting and diagnosing tuberculosis in Mycobacterium tuberculosis-exposed rhesus macaques

Application of metagenomic next-generation sequencing in HIV-negative hematogenous disseminated tuberculosis

Harnessing the gut microbiome to combat tuberculosis: a technological and clinical review

Construction and verification of early diagnosis model of tuberculous meningitis

Endothelial, cytokine, and Th1/cellular host biomarkers discriminate complicated osteoarticular tuberculosis: a prospective single-center cohort study with ROC analysis

Multiparameter antigen-specific immunoprofiling in subjects with negative IGRA and TST results with potential M. tuberculosis exposures

Machine learning prediction of pharmacist intervention benefit in tuberculosis patients using clinical parameters: a single-center retrospective study

EBUS-TBNA needle rinse fluid: a superior specimen for the molecular diagnosis of intrathoracic lymph node tuberculosis

Effect of PPD inoculation on serum cytokine profiles in latent tuberculosis infection populations

Validation and interpretation of machine-learning models for rapid identification of active tuberculosis infection using routine laboratory indicators

Diagnostic Performance of Metagenomic Next-Generation Sequencing in Mycobacterium and non-Mycobacterium infection Patients: A Retrospective Study at a Large Comprehensive Medical Center

Immune-Inflammatory Profiles and Disease Severity in Pulmonary Tuberculosis Complicated by Central Nervous System Tuberculosis

Frontiers in Cellular and Infection Microbiology

Clinical and Diagnostic Microbiology and Immunology