Immunopharmacology in Skin Cancer: Progress, Challenges, and Future Directions

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REVIEW

Published on 03 Sep 2026

Molecular reprogramming in cutaneous melanoma: the central role of G9a and EZH2 methyltransferase inhibitors in tumor plasticity, immune evasion, and therapeutic resistance

  • Melissa Yoshimi Sakamoto Maeda Nisimoto
  • Daniel Arcuschin de Oliveira
  • Heitor Raia Bottura
  • Wagner Robson Germano Sousa
  • Gabrielle do Nascimento Sividanes
  • Amanda Fáris Marques
  • Jaciara Moreira Sodré Hunnicutt
  • Alexandre Giannecchini Romagnolo
  • Maria Clara Ferreira Vivi
  • 5 more
  • Renato Santos de Oliveira Filho
doi 10.3389/fphar.2026.1879451
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