From Gynecologic Treatment to Birth Outcomes: Obstetric Sequelae After Benign and Malignant Interventions

Gynecologic treatments, whether for benign conditions such as endometriosis, fibroids, or cervical dysplasia, or for malignant diseases requiring fertility-sparing or radical interventions, can have profound implications on subsequent obstetric and perinatal outcomes. Increasing evidence suggests that surgical and medical interventions in gynecology may influence fertility potential, pregnancy complications and maternal-fetal health.

This Research Topic aims to comprehensively evaluate the obstetric sequelae of gynecologic treatments, connecting the fields of gynecology and obstetrics. It will address how diagnostic, surgical, and pharmacologic strategies in gynecology shape reproductive trajectories, with a particular focus on fertility preservation, obstetric complications, and perinatal outcomes. By promoting interdisciplinary dialogue, this collection aims to advance clinical practice and enhance counseling for women who face both gynecologic diseases and reproductive planning.

We welcome contributions, including original research, systematic reviews and meta-analyses, addressing, but not limited to, the following themes:

• Obstetric and perinatal outcomes after surgery for benign gynecologic conditions
• Fertility-sparing treatments in gynecologic oncology and their impact on pregnancy and neonatal health
• Biomarkers and predictors of reproductive outcomes following gynecologic interventions
• Long-term maternal and neonatal outcomes after conservative and radical gynecologic treatments
• Innovative preventive and surgical strategies minimizing reproductive sequelae




Please note: Manuscripts consisting solely of bioinformatics, computational analysis, or predictions of public databases which are not accompanied by validation (independent clinical or patient cohort, or biological validation in vitro or in vivo, which are not based on public databases) are not suitable for publication in this journal.

Article types and fees

This Research Topic accepts the following article types, unless otherwise specified in the Research Topic description:

• Brief Research Report
• Case Report
• Clinical Trial
• Editorial
• FAIR² Data
• Hypothesis and Theory
• Methods
• Mini Review
• Opinion
• ... View all formats

Articles that are accepted for publication by our external editors following rigorous peer review incur a publishing fee charged to Authors, institutions, or funders.

Article types

This Research Topic accepts the following article types, unless otherwise specified in the Research Topic description:

• Brief Research Report
• Case Report
• Clinical Trial
• Editorial
• FAIR² Data
• Hypothesis and Theory
• Methods
• Mini Review
• Opinion
• Original Research
• Perspective
• Review
• Specialty Grand Challenge
• Systematic Review
• Technology and Code

Keywords: Gynecologic treatments; Obstetric sequelae; Fertility preservation; Perinatal outcomes; Maternal-fetal health; Gynecologic oncology; Reproductive outcomes.

Important note: All contributions to this Research Topic must be within the scope of the section and journal to which they are submitted, as defined in their mission statements. Frontiers reserves the right to guide an out-of-scope manuscript to a more suitable section or journal at any stage of peer review.