Model Organisms and Experimental Models: Opportunities and Challenges in Vascular Physiology Research

Background
Model organisms and a wide set of experimental models have long been widely used in the field of biosciences, including a range of subject areas within physiology. Several important milestones have been achieved in the field thanks to their application, allowing scientists to develop concepts, technologies, and methodologies to better understand more complex living systems, including humans.

Goals
In addition to focusing on the many advantages of using model organisms and several experimental models in the field of Vascular Physiology, this Research Topic also aims to shed light on the challenges and limitations that accompany their application. This collection covers, but is not limited to, the following model organisms and experimental models:
- In vivo rodent models of vascular dysfunction in different disease models
- In vitro models using normal vascular beds (including the use of tissue, 2D cell co-culture, 3D cell culture/organoids) derived from humans or animals and subjected to in vitro insults
- Studying the vascular function of human vascular beds from patients undergoing surgical procedures
- Studying the physiology and pathophysiology of the placental barrier
- Studying the impact of ion channels and receptor proteins on blood flow regulation in the brain
- Role of modulators of platelet aggregation in vascular function
- Studying the physiology and pathophysiology of the blood flow regulation in the systemic and/or pulmonary circulation

Scope and information for Authors
Manuscripts submitted to this Research Topic should be in line with the scope of the Vascular Physiology section. ​Several article types will be considered, please find more information here. ​The submission of review articles and original research papers are particularly welcome to this Research Topic.

This Research Topic is part of the Experimental Models and Model Organisms series of Frontiers in Physiology. Other titles in this series include:

• Model Organisms and Experimental Models in Membrane Physiology and Membrane Biophysics: Opportunities and Challenges
• In Vitro Models: Opportunities and Challenges in Aquatic Physiology
• Animal Models and Transgenic Technology in Craniofacial Biology
• Advances in Pluripotent Stem Cell-Based in Vitro Models of the Human Heart for Cardiac Physiology, Disease Modeling and Clinical Applications
• Experimental Models and Model Organisms in Cardiac Electrophysiology: Opportunities and Challenges
• Model Organisms: Opportunities and Challenges in Developmental Physiology
• Invertebrates as Model Organisms: Opportunities and Challenges in Physiology and Bioscience Research
• Model Organisms and Experimental Models: Opportunities and Challenges in Musculoskeletal Physiology
• Model Organisms and Experimental Models: Opportunities and Challenges in Integrative Physiology
• Model Organisms and Experimental Models: Opportunities and Challenges in Redox Physiology
• Experimental Models of Rare Cardiac Diseases

Keywords: model organisms, experimental models, vascular physiology, platelets, placental barrier, vascular beds, organoids, blood flow regulation, #CollectionSeries

Important note: All contributions to this Research Topic must be within the scope of the section and journal to which they are submitted, as defined in their mission statements. Frontiers reserves the right to guide an out-of-scope manuscript to a more suitable section or journal at any stage of peer review.