Malignancies of endocrine organs, such as the pituitary, thyroid, parathyroid, and adrenal glands, significantly affect the metabolism of patients, leading to poor prognosis and high mortality; In addition, malignancies of other organs (such as the pancreas and lung) also cause endocrine or metabolic syndromes, such as Cushing's syndrome, hypoglycemia, hypercalcemia, male mammogenesis, which are called para-neoplastic syndrome. Moreover, the commonly used chemo-, targeted- and immune therapeutic agents (especially immunocheckpoint inhibitors) also have non-negligible impacts on endocrine homeostasis, sometimes life-threatening, through various potential mechanisms.
This Research Topic aims to spotlight the direct endocrine consequences of malignancies from endocrine or other organs. Also, it seeks to investigate indirect endocrine consequences of malignancies after therapeutic treatments.
We welcome Original Research, Review, Case Report, Opinion, and Perspective articles on the following sub-topics, including but not limited to:
• Clinical trials, new insights, novel clinical experience or promising strategies for endocrine malignancies;
• Advances in knowledge and management of endocrine adverse events in cancer therapy;
• Molecules or parameters that would predict the curative effect and prognosis of endocrine malignancies;
• Molecules or parameters that would predict endocrine adverse events.
Keywords: endocrine tumor, para-neoplastic syndrome, endocrine side effect
Important note: All contributions to this Research Topic must be within the scope of the section and journal to which they are submitted, as defined in their mission statements. Frontiers reserves the right to guide an out-of-scope manuscript to a more suitable section or journal at any stage of peer review.
