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Study Protocol

Accepted on 22 Oct 2025

Study protocol of a multicenter, randomized, non-inferiority, open-label study investigating the efficacy of a fixed-dose combination regimen of dapagliflozin/metformin versus co-administered dual therapy based on glycemic control, satisfaction and adherence in patients with newly diagnosed type 2 diabetes mellitus

in Translational and Clinical Endocrinology

  • Jiaxuan Wang
  • Ying Wei
  • Ping Shi
  • Ji Chen
  • Lingling Xu
  • Yinghong Kong
  • Jun Ye
  • Xueqin Wang
  • Juan Xu
  • Guang Wang
Frontiers in Endocrinology
doi 10.3389/fendo.2025.1690339