Preclinical Stage | List of Frontiers open access articles

Original Research

Accepted on 03 Oct 2025

Exploring Challenges to Medication Adherence among Young and Middle aged Adults with Coronary Heart Disease in China: A Qualitative Study

in Cardiovascular Nursing

Jianli Guo
Jian Ma
Mengqi Xu
Xiaoli Huang
Yuan Ding
Lingyan Zhu
Wengui Zheng

Frontiers in Cardiovascular Medicine

doi 10.3389/fcvm.2025.1664013

145 views

Clinical Trial

Accepted on 03 Oct 2025

Weizmannia coagulans BC99 regulates oxidative stress and serum metabolic pathways to improve allergic rhinitis: a randomized, double-blind, placebo-controlled trial

in Microbial Immunology

Xuan Li
Zhidong Han
Kaihong Wu
Saman Azeem
Bingchai Lin
Yiru Jiang
Yao Dong
Zhonghui Gai
Shuguang Fang
Ying Wu

Frontiers in Immunology

doi 10.3389/fimmu.2025.1654724

129 views

Review

Accepted on 03 Oct 2025

Lactylation and Antitumor Immunity

in Cancer Immunity and Immunotherapy

Huabao Xiong
Biao Yang
Lingyu Li
Dongmei Shi
Tao Zhong

Frontiers in Immunology

doi 10.3389/fimmu.2025.1690068

128 views

Case Report

Accepted on 03 Oct 2025

Ataxia, intentional tremor and hypotonia syndrome caused by a novel POU4F1 gene mutation: a case report

in Neurogenomics

Qisheng Hu
Feng Zhu
Wanfen Wang
Yihang Xu
Haiyan Ren
Yanni Zheng
Yi-Qing Jiang
Shaofa Ke

Frontiers in Genetics

doi 10.3389/fgene.2025.1702803

184 views

Original Research

Accepted on 03 Oct 2025

Healthcare Practitioners' Acceptance of Using Telehealth in the Kingdom of Saudi Arabia: An Application of the Unified Theory of Acceptance and Use of Technology Model

in Human Factors and Digital Health

Abdullah A Almojaibel
Abdulelah Aldhahir
Khalid Aldilaijan
Rayyan Almusally
Marah Alatrash
Mohammed Alkhofi
Saeed Alghamdi
Yousef Alqurashi
Mohammed Alsubaiei
Khalid AlHarkan

Frontiers in Digital Health

doi 10.3389/fdgth.2025.1659997

217 views

Original Research

Accepted on 03 Oct 2025

Human leukocyte antigen-G isoform HLA-G2/6, but not HLA-G1/4/5, is an independent indicator of poor survival in patients with colorectal cancer

in Immunological Tolerance and Regulation

Xia Zhang
Qiu-Yue Han
Jian-Gang Zhang
Jiao Lin
Wei-Hua Yan
Aifen Lin

Frontiers in Immunology

doi 10.3389/fimmu.2025.1672144

143 views

Correction

Accepted on 03 Oct 2025

Correction: Bioprospecting of novel silica solubilizing bacteria as bioinoculants for sustainable silica management

in Microbiological Chemistry and Geomicrobiology

Elina Maharjan
Sonam Mahawar
Surya Chauhan
Sudhir Kumar Upadhyay
Santosh Ranjan Mohanty
AJAZ AHMAD
Rajesh Kumar Singh
Devendra Jain

Frontiers in Microbiology

doi 10.3389/fmicb.2025.1717737

177 views

Original Research

Accepted on 03 Oct 2025

Prognostic Significance of Peripheral Blood Inflammatory Biomarkers (SII, PLR, NLR, LMR, SIRI, PIV, PNI) in Lip Cancer: NLR as an Independent Biomarker for Survival Outcomes

in Head and Neck Cancer

Zhilin Li
Wei An
Bin Wang
Zening Yan
Liangbin Gao
Jiaming Wang
Hongmei Yu
Shuxin Wen

Frontiers in Oncology

doi 10.3389/fonc.2025.1676824

158 views

Original Research

Accepted on 03 Oct 2025

A Novel Surface Plasmon-Based Sensor for Liquid Refractive Index Measurement with Biochemical Sensing Capabilities

in Optics and Photonics

Shubin Yan
Weijie Yang
Chong Wang
Zhaokun Yan
Taiquan Wu

Frontiers in Physics

doi 10.3389/fphy.2025.1676348

180 views

Brief Research Report

Accepted on 03 Oct 2025

Soil-Water Characteristics Curve and Permeability Function of Concrete Waste

in Geotechnical Engineering

Fathiyah Hakim Sagitaningrum
Abdul Halim Hamdany
Glenn Adriel Adiguna
Martin Wijaya
Widjojo Adi Prakoso
Wiwik Rahayu
Eriko Dewangga
Alfrendo Satyanaga

Frontiers in Built Environment

doi 10.3389/fbuil.2025.1674281

238 views

Original Research

Accepted on 03 Oct 2025

The Impact of High-intensity Interval Training on Cerebrovascular Function in The APP/PS1 Mice

in Interventions in Aging

Jingyun Hu
Lei Zhu
Ming Cai
Zhe Lu
Qi Wang
Teng Zhai

Frontiers in Aging

doi 10.3389/fragi.2025.1647628

221 views

Original Research

Accepted on 03 Oct 2025

Deep Learning-Based Automated Quantification System for Abdominal Aortic Calcification: Multicenter Cohort Study for Algorithm Development and Clinical Validation

in Cardiovascular Imaging

Zhenhong Shao
Enhui Xin
Lisong Chen
Aie Liu
Chaochao Gu
Aijing Li
Yuning Pan

Frontiers in Cardiovascular Medicine

doi 10.3389/fcvm.2025.1647882

195 views

Original Research

Accepted on 03 Oct 2025

Mediating Role of Digital Ethics on the Impact of Artificial Intelligence Usage and Public Relations Practices: Evidence from Malaysia

in AI in Business

Umaima Khalid
Mokhtarrudin Ahmad
Tak Jie Chan
MAHIR PRADANA
Satnam Singh

Frontiers in Artificial Intelligence

doi 10.3389/frai.2025.1662219

752 views

Correction

Accepted on 03 Oct 2025

Correction: Real-world outcomes of immune checkpoint inhibitors as second-line therapy for extensive-stage small-cell lung cancer: a multicenter retrospective analysiste for authors

in Cancer Immunity and Immunotherapy

Jiao Zhang
Jiaxing Guo
Ping Li
Xiaoye jin
Yan Wang
Lujun Zhao

Frontiers in Immunology

doi 10.3389/fimmu.2025.1708889

138 views

Original Research

Accepted on 03 Oct 2025

The impact of water flow rate on the dynamic dissolution kinetics of fractured limestone formations

in Georeservoirs

Dabao Xu
Yuhang Ma
Feng Bo
Mingming Fan
Zhenchuan Han

Frontiers in Earth Science

doi 10.3389/feart.2025.1701477

255 views

Study Protocol

Accepted on 03 Oct 2025

Protocol for the "Stand the Future" Trial: Robotic Exoskeleton Gait Training for Non-Ambulatory Children with Spastic Cerebral Palsy

in Neurorehabilitation

Beier Xia
Zhixiang Wen
Na Mi
Yang Zhang

Frontiers in Neurology

doi 10.3389/fneur.2025.1651913

Articles

Exploring Challenges to Medication Adherence among Young and Middle aged Adults with Coronary Heart Disease in China: A Qualitative Study

Weizmannia coagulans BC99 regulates oxidative stress and serum metabolic pathways to improve allergic rhinitis: a randomized, double-blind, placebo-controlled trial

Lactylation and Antitumor Immunity

Ataxia, intentional tremor and hypotonia syndrome caused by a novel POU4F1 gene mutation: a case report

Healthcare Practitioners' Acceptance of Using Telehealth in the Kingdom of Saudi Arabia: An Application of the Unified Theory of Acceptance and Use of Technology Model

Human leukocyte antigen-G isoform HLA-G2/6, but not HLA-G1/4/5, is an independent indicator of poor survival in patients with colorectal cancer

Correction: Bioprospecting of novel silica solubilizing bacteria as bioinoculants for sustainable silica management

Prognostic Significance of Peripheral Blood Inflammatory Biomarkers (SII, PLR, NLR, LMR, SIRI, PIV, PNI) in Lip Cancer: NLR as an Independent Biomarker for Survival Outcomes

A Novel Surface Plasmon-Based Sensor for Liquid Refractive Index Measurement with Biochemical Sensing Capabilities

Soil-Water Characteristics Curve and Permeability Function of Concrete Waste

The Impact of High-intensity Interval Training on Cerebrovascular Function in The APP/PS1 Mice

Deep Learning-Based Automated Quantification System for Abdominal Aortic Calcification: Multicenter Cohort Study for Algorithm Development and Clinical Validation

Mediating Role of Digital Ethics on the Impact of Artificial Intelligence Usage and Public Relations Practices: Evidence from Malaysia

Correction: Real-world outcomes of immune checkpoint inhibitors as second-line therapy for extensive-stage small-cell lung cancer: a multicenter retrospective analysiste for authors

The impact of water flow rate on the dynamic dissolution kinetics of fractured limestone formations

Protocol for the "Stand the Future" Trial: Robotic Exoskeleton Gait Training for Non-Ambulatory Children with Spastic Cerebral Palsy