Original Research ARTICLE
Sliding crosslinked thermoresponsive materials: polypseudorotaxanes made of poly(N-isopropylacrylamide) and acrylamide-γ-cyclodextrin
- 1Politecnico di Torino, Italy
- 2Dipartimento di Chimica e Farmacia, Università degli Studi di Sassari, Italy
Novel polypseudorotaxanes based on poly(N-isopropylacrylamide) (PNIPAAm) and acrylamide-γ-cyclodextrin (AγCD) are successfully synthesized. AγCD gives rise to sliding crosslinking systems and influences the thermoresponsive and swelling behavior of PNIPAAm hydrogels. Namely, their lower critical solution temperature can be tuned up to 38 °C, thus making the resulting materials of great interest in biomedical applications. Also, AγCD influences the thermal and mechanical properties of hydrogels, by affecting the Tg and E modulus values.
Keywords: thermoresponsive materials, polypseudorotaxane, PNIPAAM (poly(N-isopropylacrylamide)), Cyclodextrin, Hydrogel, LCST
Received: 18 Sep 2018;
Accepted: 08 Nov 2018.
Edited by:Clemens K. Weiss, Fachhochschule Bingen, Germany
Reviewed by:Domenico Larobina, Italian National Research Council, Italy
Jonas G. Croissant, University of New Mexico, United States
Copyright: © 2018 Malucelli, Dore, Sanna, Nuvoli, Rassu, Mariani and Alzari. This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.
Prof. Alberto Mariani, Dipartimento di Chimica e Farmacia, Università degli Studi di Sassari, Sassari, 07100, Italy, email@example.com
PhD. Valeria Alzari, Dipartimento di Chimica e Farmacia, Università degli Studi di Sassari, Sassari, 07100, Italy, firstname.lastname@example.org