In the original article, there was an error. “EBI-3” was misspelled as “EB1-3” in the title of the manuscript, supplementary material, and in the citation.
A correction has been made to the Title:
“EBI-3 chain of IL-35 along with TGF-β synergistically regulate anti-leishmanial immunity”
Additionally, “EBI-3 and p35 chains of IL-35” was mistakenly referred to as “EBI-3 and p35 chains of EBI-3.”
A correction has been made to the Abstract:
“Immunosuppression is a characteristic feature of chronic leishmaniasis. The dynamicity and the functional cross talks of host immune responses during Leishmania infection are still not clearly understood. Here we explored the functional aspects of accumulation of immune suppressive cellular and cytokine milieu during the progression of murine visceral leishmaniasis. In addition to IL-10 and TGF-β, investigation on the responses of different subunit chains of IL-12 family revealed a progressive elevation of EBI-3 and p35 chains of IL-35 with Leishmania donovani infection in BALB/c mice. The expansion of CD25 and FoxP3 positive T cells is associated with loss of IFN-γ and TNF-α response in advanced disease. Ex-vivo and in vivo neutralization of TGF-β and EBI-3 suggests a synergism in suppression of host anti-leishmanial immunity. The down-regulation of EBI-3 and TGF-β is crucial for re-activation of JAK-STAT pathway for induction as well as restoration of protective immunity against L. donovani infection.”
The authors apologize for these errors and state that they do not change the scientific conclusions of the article in any way. The original article has been updated.
Summary
Keywords
regulatory T cells, Leishmania, immune response, interleukin-35, transforming growth factor beta, immune suppression
Citation
Asad M, Sabur A, Shadab M, Das S, Kamran M, Didwania N and Ali N (2019) Corrigendum: EBI-3 Chain of IL-35 Along With TGF-β Synergistically Regulate Anti-leishmanial Immunity. Front. Immunol. 10:2409. doi: 10.3389/fimmu.2019.02409
Received
30 July 2019
Accepted
26 September 2019
Published
18 October 2019
Approved by
Frontiers Editorial Office, Frontiers Media SA, Switzerland
Volume
10 - 2019
Updates
Copyright
© 2019 Asad, Sabur, Shadab, Das, Kamran, Didwania and Ali.
This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.
*Correspondence: Nahid Ali nali@iicb.res.in
†Present address: Mohammad Asad, School of Medicine, Department of Dermatology, University of Alabama at Birmingham, Birmingham, AL, United States
This article was submitted to Microbial Immunology, a section of the journal Frontiers in Immunology
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