CORRECTION article

Front. Immunol., 27 July 2021

Sec. Immunological Tolerance and Regulation

Volume 12 - 2021 | https://doi.org/10.3389/fimmu.2021.737303

Corrigendum: The Nrf2-Antioxidant Response Element Signaling Pathway Controls Fibrosis and Autoimmunity in Scleroderma

  • 1. Laboratoire d’Immunologie, Hôpital Cochin, Paris, France

  • 2. INSERM U1016, Institut Cochin, Paris, France

  • 3. UMR996 - Inflammation, Chemokines and Immunopathology, INSERM, Univ Paris-Sud, Université Paris-Saclay, Châtenay-Malabry, France

  • 4. Service de Rhumatologie, Hôpital Cochin, Paris, France

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In the original article, there was a mistake in the legend for Figure 3G and 6I as published. Skin and lung biopsies were stained with Haematoxylin and Eosin, and not “with picro-sirius red and Haematoxylin and Eosin” as stated in the original legend. The correct legends appear below. The authors apologize for this error and state that this does not change the scientific conclusions of the article in any way. The original article has been updated.

Figure 3G

Figure 3G

(F, G) Skin and Lung biopsies stained with Hematoxylin and eosin (H&E).

Figure 6I

Figure 6I

(I) Skin and lung biopsies stained with Hematoxylin and eosin (H&E).

In the original article, there was a mistake in the photos used in Figures 3G and 6I as published. The authors noticed that some of the lung histology photos used in Figures 3 and 6 as illustrations only were not correct due to an inadvertent mishandling of the names list and photo files. The corrected Figures 3 and 6 appear below. The authors apologize for this error and state that this does not change the scientific conclusions of the article in any way, as these photos were used as illustrations only, and not as a source of quantifiable data. The original article has been updated.

In the original article, there was an error in the Methods section: “A 5-μm-thick tissue section was prepared from the mid-portion of paraffin-embedded tissue and stained with H&E or picro-sirius red.”

A correction has been made in the text of the Methods section, Assessment of Skin Thickness and Collagen Accumulation in Skin and Lungs, paragraph 1:

“A 5-μm-thick tissue section was prepared from the mid-portion of paraffin-embedded tissue and stained with H&E.”

In the original article, there was an error in the Results section: “Staining of skin and lung biopsies with picro-sirius red also showed a reduction in fibrosis in both organs in diseased-mice treated with DMF compared to untreated diseased-mice (Figure 6I).”

A correction has been made in the text of the Results section, Treatment of HOCl-mice with DMF prevents the development of SSc, paragraph 1:

“Staining of skin and lung biopsies with Hematoxylin and Eosin also showed a reduction in fibrosis in both organs in diseased-mice treated with DMF compared to untreated diseased-mice (Figure 6I).”

The authors apologize for this error and state that this does not change the scientific conclusions of the article in any way. The original article has been updated.

Publisher’s Note

All claims expressed in this article are solely those of the authors and do not necessarily represent those of their affiliated organizations, or those of the publisher, the editors and the reviewers. Any product that may be evaluated in this article, or claim that may be made by its manufacturer, is not guaranteed or endorsed by the publisher.

Summary

Keywords

systemic sclerosis, oxidative stress, fibrosis, inflammation, Nrf2

Citation

Kavian N, Mehlal S, Jeljeli M, Saidu NEB, Nicco C, Cerles O, Chouzenoux S, Cauvet A, Camus C, Ait-Djoudi M, Chéreau C, Kerdine-Römer S, Allanore Y and Batteux F (2021) Corrigendum: The Nrf2-Antioxidant Response Element Signaling Pathway Controls Fibrosis and Autoimmunity in Scleroderma. Front. Immunol. 12:737303. doi: 10.3389/fimmu.2021.737303

Received

06 July 2021

Accepted

12 July 2021

Published

27 July 2021

Volume

12 - 2021

Edited and reviewed by

Danièle Noël, U1183 Cellules Souches, Plasticité Cellulaire, Médecine Régénératrice Et Immunothérapies (INSERM), France

Updates

Copyright

*Correspondence: Frederic Batteux,

This article was submitted to Immunological Tolerance and Regulation, a section of the journal Frontiers in Immunology

Disclaimer

All claims expressed in this article are solely those of the authors and do not necessarily represent those of their affiliated organizations, or those of the publisher, the editors and the reviewers. Any product that may be evaluated in this article or claim that may be made by its manufacturer is not guaranteed or endorsed by the publisher.

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