CORRECTION article

Front. Immunol., 01 October 2021

Sec. Alloimmunity and Transplantation

Volume 12 - 2021 | https://doi.org/10.3389/fimmu.2021.763236

Corrigendum: Factors Predicting the Presence of Maternal Cells in Cord Blood and Associated Changes in Immune Cell Composition

  • 1. INSERM UMRs 1097 Arthrites Autoimmunes, Aix Marseille Université, Marseille, France

  • 2. Department of Obstetrics and Gynecology, St Joseph Hospital, Marseille, France

  • 3. Department of Gynaecology and Obstetrics, Pôle Femme Enfant, AP-HM, Assistance Publique-Hôpitaux de Marseille, AMU, Aix-Marseille Université, France

  • 4. CIC1409, AMU, AP-HM, Marseille, France

  • 5. Centre National de la Recherche Scientifique (CNRS) UMR7268 (ADES), “Biologie des Groupes Sanguin”, Marseille, France

  • 6. Etablissement Français du Sang (EFS), Marseille, France

  • 7. Service de Rhumatologie, Hôpital Sainte Marguerite, AP-HM, Marseille, France

In the original article, there was a mistake in the legend for Figure 1 as published. The value of MMc in WB for CB#45 indicated in the legend of Figure 1 corresponded to the value of MMc (305 gEq) per number of host cells tested per experiment (~246, 000 gEq), not per million of host cells. The correct legend appears below.

Figure 1

The correct legend appears below Figure 1.

In the original article, there was a mistake in the legend for Figure 3B as published. As the values of MMc in WB indicated corresponded to the values of MMc per number of host cells tested per experiment (mean ~212,360 gEq ±31,110), not per million of host cells, this results in minimal changes in the p value. Moreover the symbols “inferior or equal to” or “superior to” did not appear correctly, they are spelled out in the corrected legend. The correct legend appears below.

Figure 3

The correct legend appears below Figure 3.

In the original article, there was a mistake in Figure 1 as published. As explained above, the values of MMc in WB indicated in the original article corresponded to the values of MMc per number of host cells tested per experiment (mean ~212,360 gEq ±31,110), not per million of host cells. The mistake was only for values in whole blood. All the other values in T cells, B cells, granulocytes and CD34+ cells are correct. The corrected Figure 1 appears below.

In the original article, there was a mistake in Figure 3B as published. Consequent to the initial mistake where values of MMc in WB were given per number of host cells tested per experiment instead of MMc per million of host cells, instead of having 11 cord blood (CB) samples with MMc ≤10 gEq, six between 10-100 gEq and four with > 100 gEq, respectively N=9, N=7 and N=5 CB corresponded to each category. Results are extremely similar to previously published data and similarly significant (P=0.002). The corrected Figure 3B appears below.

In the original article, there was an error in Patients and Methods, Statistics, paragraph 2 as published: “The number of maternal cells per million of CB cells found per subset was added up for all the subsets and divided by the number of subsets tested, giving mean values of total MMc per CB ranging from 0.3 to 744 gEq/106”. The values of MMc in WB indicated in the text corresponded to the values of MMc per number of host cells tested per experiment (mean ~212,360 gEq ±31,110), not per million of host cells.

A correction has been made to the text as follows: “The number of maternal cells per million of CB cells found per subset was added up for all the subsets and divided by the number of subsets tested, giving mean values of total MMc per CB ranging from 0.3 to 818 gEq/106.”

In the original article, there was an error in Results, paragraph 3 as published: “Among the 30 samples positive for MMc, four had high quantities of MMc in whole blood comprised between 110 and 305 gEq/106 of cord blood cells (75th percentile of positive values)”.

A correction has been made to the text as follows: “Among the 30 samples positive for MMc, four had high quantities of MMc in whole blood comprised between 226 and 1240 gEq/106 of cord blood cells.”

The authors apologize for these errors and state that this does not change the scientific conclusions of the article in any way. The original article has been updated.

Publisher’s Note

All claims expressed in this article are solely those of the authors and do not necessarily represent those of their affiliated organizations, or those of the publisher, the editors and the reviewers. Any product that may be evaluated in this article, or claim that may be made by its manufacturer, is not guaranteed or endorsed by the publisher.

Summary

Keywords

cord blood, maternal microchimerism, PAPP-A, HLA compatibility, NK cells, transplantation

Citation

Haddad ME, Karlmark K, Donato X-C, Martin G, Bretelle F, Lesavre N, Cocallemen J-F, Martin M, Picard C, Roudier J, Desbriere R and Lambert NC (2021) Corrigendum: Factors Predicting the Presence of Maternal Cells in Cord Blood and Associated Changes in Immune Cell Composition. Front. Immunol. 12:763236. doi: 10.3389/fimmu.2021.763236

Received

23 August 2021

Accepted

06 September 2021

Published

01 October 2021

Volume

12 - 2021

Edited and reviewed by

Antoine Toubert, Université Paris Diderot, France

Updates

Copyright

*Correspondence: Nathalie C. Lambert,

This article was submitted to Alloimmunity and Transplantation, a section of the journal Frontiers in Immunology

Disclaimer

All claims expressed in this article are solely those of the authors and do not necessarily represent those of their affiliated organizations, or those of the publisher, the editors and the reviewers. Any product that may be evaluated in this article or claim that may be made by its manufacturer is not guaranteed or endorsed by the publisher.

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