CORRECTION article

Front. Microbiol., 31 October 2017

Sec. Microbial Immunology

Volume 8 - 2017 | https://doi.org/10.3389/fmicb.2017.02172

Corrigendum: Molecular Cloning, Characterization, and Anti-avian Pathogenic Escherichia coli Innate Immune Response of the Cherry Valley Duck CIITA Gene

  • 1. Sino-German Cooperative Research Centre for Zoonosis of Animal Origin of Shandong Province, College of Veterinary Medicine, Shandong Agricultural University, Tai'an, China

  • 2. Collaborative Innovation Center for the Origin and Control of Emerging Infectious Diseases, Taishan Medical University, Tai'an, China

  • 3. Shandong Provincial Key Laboratory of Animal Biotechnology and Disease Control and Prevention, Shandong Agricultural University, Tai'an, China

  • 4. Shandong Provincial Engineering Technology Research Center of Animal Disease Control and Prevention, Shandong Agricultural University, Tai'an, China

In the original article Accolla et al. (1985, 1986) were not cited in the article. In addition, we erroneously stated the years in which CIITA was discovered; it should have been 1985–1986. The citation and correct date have been inserted in introduction, second paragraph.

The corrected paragraph should read:

In mammals, NLRs are able to recognize bacterial flagella, lipopolysaccharide, RNA, and muramyl dipeptides in the cytoplasm (Franchi et al., 2009). NLRs can be divided into five subfamilies according to the difference in the N-terminal effector domain (Ting and Davis, 2005). Class II major histocompatibility complex (MHC-II) transactivator (CIITA), discovered in 1985–1986 (Accolla et al., 1985, 1986), and contains an acidic transcriptional activation motif in the N-terminal domain, so it belongs to the NLRA subfamily. CIITA plays an important role in the MHC-II transcriptional activation and is positively correlated with the MHC-II transcription level (Muhlethaler-Mottet et al., 1997; Zuo and Rowe, 2012). In addition, CIITA can regulate the presentation function of antigen presentation cells by controlling the transcription level of MHC-II (van den Elsen et al., 2004; Lupfer and Kanneganti, 2012). However, CIITA does not directly bind to DNA but rather acts as a transcriptional co-activator through the activation of transcription factors (Sisk et al., 2003). In addition, CIITA can trans-activate the expression of MHC-II in antigen presentation cells and virus-infected target cells, inducing host-derived antiviral responses, thereby inhibiting the viral replication in the host and eliminating virus infection (Tosi et al., 2011).

The authors apologize for this error and state that this does not change the scientific conclusions of the article in any way.

Statements

Conflict of interest

The authors declare that the research was conducted in the absence of any commercial or financial relationships that could be construed as a potential conflict of interest.

References

  • 1

    AccollaR. S.JotterandbellomoM.ScarpellinoL.MaffeiA.CarraG.GuardiolaJ. (1986). aIr-1, a newly found locus on mouse chromosome 16 encoding a trans-acting activator factor for MHC class II gene expression. J. Exp. Med.164, 369374.

  • 2

    AccollaR. S.ScarpellinoL.CarraG.GuardiolaJ. (1985). Trans-acting element(s) operating across species barriers positively regulate expression of major histocompatibility complex class II genes. J. Exp. Med.162:1117.

  • 3

    FranchiL.WarnerN.VianiK.NuñezG. (2009). Function of Nod-like receptors in microbial recognition and host defense. Immunol. Rev.227, 106128. 10.1111/j.1600-065X.2008.00734.x

  • 4

    LupferC. R.KannegantiT.-D. (2012). The role of inflammasome modulation in virulence. Virulence3, 262270. 10.4161/viru.20266

  • 5

    Muhlethaler-MottetA.OttenL. A.SteimleV.MachB. (1997). Expression of MHC class II molecules in different cellular and functional compartments is controlled by differential usage of multiple promoters of the transactivator CIITA. EMBO J.16, 28512860. 10.1093/emboj/16.10.2851

  • 6

    SiskT. J.NickersonK.KwokR. P.ChangC. H. (2003). Phosphorylation of class II transactivator regulates its interaction ability and transactivation function. Int. Immunol.15, 11951205. 10.1093/intimm/dxg116

  • 7

    TingJ. P.DavisB. K. (2005). CATERPILLER: a novel gene family important in immunity, cell death, and diseases. Annu. Rev. Immunol.23, 387414. 10.1146/annurev.immunol.23.021704.115616

  • 8

    TosiG.ForlaniG.AndresenV.TurciM.BertazzoniU.FranchiniG.et al. (2011). Major histocompatibility complex class II transactivator CIITA is a viral restriction factor that targets human T-cell lymphotropic virus type 1 Tax-1 function and inhibits viral replication. J. Virol.85, 1071910729. 10.1128/JVI.00813-11

  • 9

    van den ElsenP. J.HollingT. M.KuipersH. F.Van Der StoepN. (2004). Transcriptional regulation of antigen presentation. Curr. Opin. Immunol.16, 6775. 10.1016/j.coi.2003.11.015

  • 10

    ZuoJ.RoweM. (2012). Herpesviruses placating the unwilling host: manipulation of the MHC class II antigen presentation pathway. Viruses4, 13351353. 10.3390/v4081335

Summary

Keywords

Cherry Valley duck, CIITA, sequence analysis, receptor expression, inflammatory cytokines, antibacterial ability, innate immunity

Citation

Li R, Guo M, Lin J, Chai T and Wei L (2017) Corrigendum: Molecular Cloning, Characterization, and Anti-avian Pathogenic Escherichia coli Innate Immune Response of the Cherry Valley Duck CIITA Gene. Front. Microbiol. 8:2172. doi: 10.3389/fmicb.2017.02172

Received

15 September 2017

Accepted

23 October 2017

Published

31 October 2017

Volume

8 - 2017

Edited and reviewed by

Juarez Antonio Simões Quaresma, Universidade Federal do Pará, Brazil

Updates

Copyright

*Correspondence: Tongjie Chai

This article was submitted to Microbial Immunology, a section of the journal Frontiers in Microbiology

†These authors have contributed equally to this work.

Disclaimer

All claims expressed in this article are solely those of the authors and do not necessarily represent those of their affiliated organizations, or those of the publisher, the editors and the reviewers. Any product that may be evaluated in this article or claim that may be made by its manufacturer is not guaranteed or endorsed by the publisher.

Outline

Cite article

Copy to clipboard


Export citation file


Share article

Article metrics