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Correction ARTICLE

Front. Microbiol., 02 April 2019 | https://doi.org/10.3389/fmicb.2019.00601

Corrigendum: Bacteroides fragilis Prevents Clostridium difficile Infection in a Mouse Model by Restoring Gut Barrier and Microbiome Regulation

Huimin Deng1, Siqi Yang1, Yucheng Zhang1, Kai Qian1, Zhaohui Zhang1, Yangyang Liu2, Ye Wang2, Yang Bai1, Hongying Fan3*, Xinmei Zhao1* and Fachao Zhi1*
  • 1Guangdong Provincial Key Laboratory of Gastroenterology, Department of Gastroenterology, Institute of Gastroenterology of Guangdong Province, Nanfang Hospital, Southern Medical University, Guangzhou, China
  • 2Guangzhou ZhiYi Biotechnology Co., Ltd., Guangzhou, China
  • 3Guangdong Provincial Key Laboratory of Tropical Disease Research, School of Public Health, Southern Medical University, Guangzhou, China

A Corrigendum on
Bacteroides fragilis Prevents Clostridium difficile Infection in a Mouse Model by Restoring Gut Barrier and Microbiome Regulation

by Deng, H., Yang, S., Zhang, Y., Qian, K., Zhang, Z., Liu, Y., et al. (2018). Front. Microbiol. 9:2976. doi: 10.3389/fmicb.2018.02976

In the original article, there was a mistake in the Supplementary Figure 3 as published. The same Figure 3 used in the original article was also used for Supplementary Figure 3. The corrected Supplementary Figure 3 appears below.

SUPPLEMENTARY FIGURE 3
www.frontiersin.org

Supplementary Figure 3. B. fragilis ZY-312 inhibits colon cell apoptosis induced by C. difficile. Representative images of PAS staining (top) for Muc-2 protein visualization in HT-29 cell monolayers are shown for all groups. Microscopic observations (middle) of Vero cell morphology and viability and PI staining (bottom) of Vero cells in all groups are shown. (A) Blank control group, 5 × 105 HT-29 or Vero cells were cultured without treatment; (B) B. fragilis group, cells were incubated with 5 × 108 cfu B. fragilis; (C) C. difficile group, cells were incubated with 5 × 107 cfu C. difficile; (D) Exclusion group, cells were infected with 5 × 108 cfu B. fragilis for the first hour and 5 × 107 cfu C. difficile for the second hour; (E) Competition group, cells were co-infected with B. fragilis and C. difficile; (F) Substitution group, cells were infected with C. difficile for the first hour and B. fragilis for the second hour. The cells were incubated at 37°C under anaerobic conditions for 2 h in total.

The authors apologize for this error and state that this does not change the scientific conclusions of the article in any way. The original Supplementary Material has been updated.

Keywords: next-generation probiotic, gut barrier, gut microbiota, Clostridium difficile, commensal bacteria

Citation: Deng H, Yang S, Zhang Y, Qian K, Zhang Z, Liu Y, Wang Y, Bai Y, Fan H, Zhao X and Zhi F (2019) Corrigendum: Bacteroides fragilis Prevents Clostridium difficile Infection in a Mouse Model by Restoring Gut Barrier and Microbiome Regulation. Front. Microbiol. 10:601. doi: 10.3389/fmicb.2019.00601

Received: 03 March 2019; Accepted: 11 March 2019;
Published: 02 April 2019.

Edited by:

George Grant, University of Aberdeen, United Kingdom

Reviewed by:

Nobuhiko Kamada, University of Michigan Health System, United States
Shailesh K. Shahi, The University of Iowa, United States

Copyright © 2019 Deng, Yang, Zhang, Qian, Zhang, Liu, Wang, Bai, Fan, Zhao and Zhi. This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

*Correspondence: Hongying Fan, biofhy@126.com
Xinmei Zhao, zxm03172011498@163.com
Fachao Zhi, zhifc41532@163.com