In the original article, there was an error. “Gram(–) bacteria” was written where “Gram(+) bacteria” should have been used.
A correction has been made to Results, Antimicrobial Activity is Related to the Lipid Composition of Pathogens, paragraph 1:
“Unlike polymyxins, our peptide could kill Gram(+) bacteria such as Staphylococcus aureus and Staphylococcus epidermidis (Supplementary Figure 2), suggesting that our peptides do not function via LPS binding. When testing other Gram(+) bacteria, we noticed that our peptides were not effective against Enterococcus faecalis at the concentrations used (32 μg/mL and lower). To examine whether the discrimination comes from the bacterial membrane differences, the membrane lipids of these two bacteria were extracted by methanol and chloroform, and TLC was used to analyze the lipid composition (Supplementary Figure 3). The data showed that E. faecalis had much lower contents of phosphatidylethanolamine (PE) and phosphatidylserine (PS) than A. baumannii (Figure 5).”
The authors apologize for this error and state that this does not change the scientific conclusions of the article in any way. The original article has been updated.
Publisher's Note
All claims expressed in this article are solely those of the authors and do not necessarily represent those of their affiliated organizations, or those of the publisher, the editors and the reviewers. Any product that may be evaluated in this article, or claim that may be made by its manufacturer, is not guaranteed or endorsed by the publisher.
Summary
Keywords
antimicrobial peptide, antibiotic-resistant, Acinetobacter baumannii, lipid, membrane, drug-resistant
Citation
Chen S-P, Chen EH-L, Yang S-Y, Kuo P-S, Jan H-M, Yang T-C, Hsieh M-Y, Lee K-T, Lin C-H and Chen RP-Y (2022) Corrigendum: A Systematic Study of the Stability, Safety, and Efficacy of the de novo Designed Antimicrobial Peptide PepD2 and Its Modified Derivatives Against Acinetobacter baumannii. Front. Microbiol. 12:821347. doi: 10.3389/fmicb.2021.821347
Received
24 November 2021
Accepted
27 December 2021
Published
14 January 2022
Volume
12 - 2021
Edited and reviewed by
Rustam Aminov, University of Aberdeen, United Kingdom
Updates
Copyright
© 2022 Chen, Chen, Yang, Kuo, Jan, Yang, Hsieh, Lee, Lin and Chen.
This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.
*Correspondence: Rita P-Y Chen pyc@gate.sinica.edu.tw
This article was submitted to Antimicrobials, Resistance and Chemotherapy, a section of the journal Frontiers in Microbiology
Disclaimer
All claims expressed in this article are solely those of the authors and do not necessarily represent those of their affiliated organizations, or those of the publisher, the editors and the reviewers. Any product that may be evaluated in this article or claim that may be made by its manufacturer is not guaranteed or endorsed by the publisher.