This article is a correction to:
Protective Role of Melatonin Against Postmenopausal Bone Loss via Enhancement of Citrate Secretion From Osteoblasts
Wacili Da
Lin Tao
Kaicheng Wen
Zhengbo Tao
Shaojie Wang
Yue Zhu- 1Department of Orthopedics, First Hospital of China Medical University, Shenyang, Liaoning, China
- 2School of Pharmaceutical Engineering, Shenyang Pharmaceutical University, Shenyang, Liaoning, China
A corrigendum on
Protective Role of Melatonin Against Postmenopausal Bone Loss via Enhancement of Citrate Secretion From Osteoblasts
by Da, W., Tao, L., Wen, K., Tao, Z., Wang, S., Zhu, Y. Front Pharmacol. 2020; 11:667. doi: 10.3389/fphar.2020.00667
In the original article, there was a mistake in Figures 3, 4 as published. In the process of rearranging the published articles, we found a problem by accident that we mistakenly uploaded the results of western blot bands in Figures 3, 4. Those western blot bands are uneven due to the instability of hardware and improper exposure operations, which may cause unnecessary misunderstandings for readers in the future. The corrected Figures 3, 4 and Supplementary Material appear below.
FIGURE 3
FIGURE 3. Melatonin enhances the ZIP-1 expression in osteoblasts. (A) western blotting results of ZIP-1 (34 kDa), CTP (34 kDa), and β-actin (42 KDa) expression in different cell groups, (B) relative expression value of ZIP-1, (C) relative expression value of CTP, and (D) immunofluorescence results of ZIP-1 expression in different cell groups, the expression of ZIP-1 in OVX was significantly lower than that in sham group, and the melatonin treatment could significantly promote the expression of ZIP-1. *P-value < 0.05, **P-value < 0.01.
FIGURE 4
FIGURE 4. Melatonin increased citrate through up-regulating ZIP-1 in osteoblasts. (A) polymerase chain reaction results of ZIP-1 knockdown and overexpression, (B) western blotting results of ZIP-1 (34 kDa) knockdown and overexpression, (C) relative expression value of ZIP-1, and (D) citrate content in osteoblasts, *P-value < 0.05, **P-value < 0.01.
The authors apologize for this error and state that this does not change the scientific conclusions of the article in any way. The original article has been updated.
Supplementary Material
The Supplementary Material for this article can be found online at: https://www.frontiersin.org/articles/10.3389/fphar.2021.652249/full#supplementary-material.
Keywords: osteoporosis, melatonin, citrate, Mineralization, Remodeling
Citation: Da W, Tao L, Wen K, Tao Z, Wang S and Zhu Y (2021) Corrigendum: Protective Role of Melatonin Against Postmenopausal Bone Loss via Enhancing Citrate Secretion in Osteoblasts. Front. Pharmacol. 12:652249. doi: 10.3389/fphar.2021.652249
Received: 12 January 2021; Accepted: 25 January 2021;
Published: 11 March 2021.
Edited and reviewed by:
Salvatore Salomone, University of Catania, ItalyCopyright © 2021 Da, Tao, Wen, Tao, Wang and Zhu. This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.
*Correspondence: Shaojie Wang, sjwang_99@163.com; Yue Zhu, zhuyuedr@163.com
†These authors have contributed equally to this work