Frontiers in Aging Neuroscience

Original Research

Published on 19 Jun 2025

The effect of periodontal status in the associations between socioeconomic status and cognitive performance: a mediation analysis in older adults

in Alzheimer's Disease and Related Dementias

Heming Zhang
Hongxia Xiang
Lin Zhang
Zhiyang Chen
Wei Liu

Frontiers in Aging Neuroscience

doi 10.3389/fnagi.2025.1524268

3,154 views

Original Research

Published on 18 Jun 2025

Elevated monocyte-to-high-density lipoprotein ratio is associated with increased risk of cognitive impairment and severe cerebral small vessel disease burden

in Neurocognitive Aging and Behavior

Yueshan Zhao
Meixi Li
Juan Zhang
Chao Wang
Mengyao Zhao
Qishuo Yang
Tianjun Wang
Peiyuan Lv

Frontiers in Aging Neuroscience

doi 10.3389/fnagi.2025.1588488

2,650 views
1 citation

Original Research

Published on 18 Jun 2025

Hemodynamic changes and their relationship with white matter hyperintensities in CSVD patients with cognitive impairment: a 4D flow study

in Neurocognitive Aging and Behavior

Jiajun Cao
Chang Yuan
Zhenpeng Zhang
Xiaoying Zhao
Yukun Zhang
Peipei Chang
Qingwei Song
Bingwei Zhang
Rui Hu
Yanwei Miao

Frontiers in Aging Neuroscience

doi 10.3389/fnagi.2025.1578288

3,041 views

Original Research

Published on 18 Jun 2025

Relationship between executive function and dual-task walking in people with Parkinson's disease

in Parkinson’s Disease and Aging-related Movement Disorders

Jun-Hong Zhou
Ray-Yau Wang
Yo-Tsen Liu
Shih-Jung Cheng
Hsin-Hsuan Liu
Yea-Ru Yang

Frontiers in Aging Neuroscience

doi 10.3389/fnagi.2025.1585524

3,261 views
1 citation

Original Research

Published on 18 Jun 2025

Impact of cognitive decline on the physical functioning of older adults in Southern Brazil: a cross-sectional study

in Alzheimer's Disease and Related Dementias

Andréa Kruger Gonçalves
Valéria Feijó Martins
Ana Carolina Kanitz
Flávia Gomes Martinez
Leonardo Alexandre Peyré-Tartaruga
Raphael Machado Castilhos
Aline Nogueira Haas

Frontiers in Aging Neuroscience

doi 10.3389/fnagi.2025.1549764

2,897 views

Original Research

Published on 17 Jun 2025

Brain microvascular calcification is increased in human donors with dementia compared to elderly controls: a pilot study

in Alzheimer's Disease and Related Dementias

Kelly A. Borges
Isabelle Lombardi
Mackenzie Sivilli
Joseph Aabye
Isabella Romano
Saud A. Nasruddin
Mugdha V. Padalkar
Daniel Moussouros
Olga V. Savinova

Frontiers in Aging Neuroscience

doi 10.3389/fnagi.2025.1557625

3,680 views
2 citations

Original Research

Published on 17 Jun 2025

Effects of West Nile virus on behavioral and cognitive performance, cortical Aβ pathology, viral loads, and immune measures of middle-aged NL-G-F/E3 and NL-G-F/E4 mice

in Alzheimer's Disease and Related Dementias

Abigail O’Niel
Christopher J. Parkins
Alexandra Pederson
Elizabeth Saltonstall
Emily Bunnell
Ria Aggarwal
Phoebe Sandholm
Kat Kessler
Henry F. Harrison
Jessica L. Smith

Frontiers in Aging Neuroscience

doi 10.3389/fnagi.2025.1600119

3,901 views

Review

Published on 16 Jun 2025

From hormones to neurodegeneration: how FSH drives Alzheimer’s disease

in Neuroinflammation and Neuropathy

Yafei Xue
Shuqi Zuo
Fei Wang
Xiaoyi Qi

Frontiers in Aging Neuroscience

doi 10.3389/fnagi.2025.1578439

5,291 views
3 citations

Original Research

Published on 16 Jun 2025

CITA GO-ON study. A community based multidomain lifestyle intervention to prevent cognitive decline. Protocol design and recruitment process

in Alzheimer's Disease and Related Dementias

Mikel Tainta
Mirian Ecay-Torres
Myriam Barandiaran
Ainara Estanga
Carolina López
Miren Altuna
Ane Iriondo
Jon Saldias
Maite Garcia-Sebastian
Marta Cañada

Frontiers in Aging Neuroscience

doi 10.3389/fnagi.2025.1539711

4,318 views
1 citation

Original Research

Published on 16 Jun 2025

The burden of Parkinson’s disease, 1990–2021: a systematic analysis of the Global Burden of Disease study 2021

in Parkinson’s Disease and Aging-related Movement Disorders

Xi-Chen Wu
Yi-Yue Dong
Yu-Chen Ying
Guang-Yan Chen
Qian Fan
Ping Yin
Yue-Lai Chen

Frontiers in Aging Neuroscience

doi 10.3389/fnagi.2025.1596392

4,755 views
5 citations

Original Research

Published on 16 Jun 2025

A high-accuracy, low-cost blood test for Alzheimer’s disease: validating P-tau181/Aβ42 in real-world cohorts

in Alzheimer's Disease and Related Dementias

Dequan Liu
Hang Li
Qing Liu
Haiyan Li
Yuanyuan Tang
Kaiting Cheng
Tong Li
Yulan Chu
Xiaodong Jia
Wenying Yu

Frontiers in Aging Neuroscience

doi 10.3389/fnagi.2025.1599761

4,397 views
1 citation

Systematic Review

Published on 16 Jun 2025

Comparisons of acupuncture therapies combining conventional treatment in the management of vascular cognitive impairment: a systematic review and network meta-analysis

in Neurocognitive Aging and Behavior

Yuan-Ling Liao
Pei-Shan Hsu
Chang-Ti Lee
Li-Jen Su
Yi-Ying Shen
Adam Tsou
Chou-Chin Lan
I-Shiang Tzeng
Guan-Ting Liu
Po-Chun Hsieh

Frontiers in Aging Neuroscience

doi 10.3389/fnagi.2025.1559388

5,343 views
1 citation

Original Research

Published on 13 Jun 2025

Investigation of gray matter volume in individuals with heart failure and preserved ejection fraction

in Neurocognitive Aging and Behavior

Tianyi Yu
Qiuyun Bai
Yiting Guo
Yuchun Yuan

Frontiers in Aging Neuroscience

doi 10.3389/fnagi.2025.1486381

2,403 views

Original Research

Published on 13 Jun 2025

Pragmatic questionnaire-based evaluation of auditory function in individuals with major neurocognitive disorders and hearing loss in diverse contexts

in Neurocognitive Aging and Behavior

Panagiotis Alexopoulos
Antonios Alexandros Demertzis
Panagiotis Biris
Polychronis Economou
Eric Frison
Piers Dawes
Iracema Leroi

Frontiers in Aging Neuroscience

doi 10.3389/fnagi.2025.1504358

3,198 views

Original Research

Published on 13 Jun 2025

Combined association of gait speed and processing speed on cardiometabolic disease mortality risk in the US older adults: a prospective cohort study from NHANES

in Neurocognitive Aging and Behavior

Hang Yang
Ye Zhou
Xiaoying Wang
Xiaoming Xu

Frontiers in Aging Neuroscience

doi 10.3389/fnagi.2025.1537413

3,288 views

Review

Published on 13 Jun 2025

Infections with Chlamydia pneumoniae and SARS-CoV-2 and Alzheimer’s disease pathogenesis

in Alzheimer's Disease and Related Dementias

Alexa Romanella
Maegan McCall
Rachel Corwin
Alaha Abdul Faruq
Emily Lingo
Sanya Bhambhani
Christine J. Hammond
Brian J. Balin

Frontiers in Aging Neuroscience

doi 10.3389/fnagi.2025.1587782

8,767 views

Brief Research Report

Published on 13 Jun 2025

Impact of sensory organization tasks on prefrontal cortex activity in older women: a comparative fNIRS study of osteoarthritis and healthy aging

in Neurocognitive Aging and Behavior

Alka Bishnoi
Yang Hu
Manuel E. Hernandez

Frontiers in Aging Neuroscience

doi 10.3389/fnagi.2025.1583447

3,301 views

Systematic Review

Published on 13 Jun 2025

Environmental risk factors, protective factors, and biomarkers for amyotrophic lateral sclerosis: an umbrella review

in Neuroinflammation and Neuropathy

Qian Wu
Junyi Yang
Yuanjie Duan
Yumei Ma
Yue Zhang
Shutong Tan
Jinke Wang
Yaxin Wang
Binhui Liu
Jian Zhang

Frontiers in Aging Neuroscience

doi 10.3389/fnagi.2025.1541779

5,381 views

Mini Review

Published on 10 Jun 2025

Targeting synaptic plasticity to bridge translational gaps in sepsis-associated encephalopathy

in Neuroinflammation and Neuropathy

Koji Hoshino

Frontiers in Aging Neuroscience

doi 10.3389/fnagi.2025.1616736

4,360 views
2 citations

Review

Published on 10 Jun 2025

Research progress of platelets in neurodegenerative diseases

in Neuroinflammation and Neuropathy

Yu Lan
Jun Ding
Tian Yu
Chi Cheng

Frontiers in Aging Neuroscience

doi 10.3389/fnagi.2025.1544605

3,872 views

Original Research

Published on 09 Jun 2025

Decoding ferroptosis in ischemic stroke: key genes and the therapeutic potential of acupuncture

in Neuroinflammation and Neuropathy

Chunxiao Wu
Zhirui Xu
Qizhang Wang
Shuping Zhu
Chunzhi Tang

Frontiers in Aging Neuroscience

doi 10.3389/fnagi.2025.1506276

4,038 views
1 citation

Original Research

Published on 09 Jun 2025

Speech sound discrimination in background noise across the lifespan: a comparative study in Mongolian gerbils and humans

in Neurocognitive Aging and Behavior

Carolin Jüchter
Chieh-Ju Chi
Rainer Beutelmann
Georg Martin Klump

Frontiers in Aging Neuroscience

doi 10.3389/fnagi.2025.1570305

2,539 views
1 citation

Study Protocol

Published on 09 Jun 2025

Study protocol: The efficacy of mushroom to prevent cognitive decline in at-risk middle-aged adults and young-olds living in the community

in Neurocognitive Aging and Behavior

Jiatong Shan
Luwen Cao
Jiuyu Guo
Kai Xuan Lim
Na Li
Yinxia Chao
Yizhen Xie
Jian Chen
Wei Ma
Su Lin Lim

Frontiers in Aging Neuroscience

doi 10.3389/fnagi.2025.1588493

6,157 views
1 citation

Systematic Review

Published on 09 Jun 2025

Research progress on microglial pyroptosis and inflammasomes: a comprehensive analysis

in Neuroinflammation and Neuropathy

Xiaofang Wang
Zhenyu Li
Bingxiang Ma
Qianfang Jia

Frontiers in Aging Neuroscience

doi 10.3389/fnagi.2025.1582579

5,771 views

7,808 articles

articles

The effect of periodontal status in the associations between socioeconomic status and cognitive performance: a mediation analysis in older adults

Elevated monocyte-to-high-density lipoprotein ratio is associated with increased risk of cognitive impairment and severe cerebral small vessel disease burden

Hemodynamic changes and their relationship with white matter hyperintensities in CSVD patients with cognitive impairment: a 4D flow study

Relationship between executive function and dual-task walking in people with Parkinson's disease

Impact of cognitive decline on the physical functioning of older adults in Southern Brazil: a cross-sectional study

Brain microvascular calcification is increased in human donors with dementia compared to elderly controls: a pilot study

Effects of West Nile virus on behavioral and cognitive performance, cortical Aβ pathology, viral loads, and immune measures of middle-aged NL-G-F/E3 and NL-G-F/E4 mice

From hormones to neurodegeneration: how FSH drives Alzheimer’s disease

CITA GO-ON study. A community based multidomain lifestyle intervention to prevent cognitive decline. Protocol design and recruitment process

The burden of Parkinson’s disease, 1990–2021: a systematic analysis of the Global Burden of Disease study 2021

A high-accuracy, low-cost blood test for Alzheimer’s disease: validating P-tau181/Aβ42 in real-world cohorts

Comparisons of acupuncture therapies combining conventional treatment in the management of vascular cognitive impairment: a systematic review and network meta-analysis

Investigation of gray matter volume in individuals with heart failure and preserved ejection fraction

Pragmatic questionnaire-based evaluation of auditory function in individuals with major neurocognitive disorders and hearing loss in diverse contexts

Combined association of gait speed and processing speed on cardiometabolic disease mortality risk in the US older adults: a prospective cohort study from NHANES

Infections with Chlamydia pneumoniae and SARS-CoV-2 and Alzheimer’s disease pathogenesis

Impact of sensory organization tasks on prefrontal cortex activity in older women: a comparative fNIRS study of osteoarthritis and healthy aging

Environmental risk factors, protective factors, and biomarkers for amyotrophic lateral sclerosis: an umbrella review

Targeting synaptic plasticity to bridge translational gaps in sepsis-associated encephalopathy

Research progress of platelets in neurodegenerative diseases

Decoding ferroptosis in ischemic stroke: key genes and the therapeutic potential of acupuncture

Speech sound discrimination in background noise across the lifespan: a comparative study in Mongolian gerbils and humans

Study protocol: The efficacy of mushroom to prevent cognitive decline in at-risk middle-aged adults and young-olds living in the community

Research progress on microglial pyroptosis and inflammasomes: a comprehensive analysis