Frontiers in Aging Neuroscience

Original Research

Published on 11 Aug 2025

Increased tau-induced inflammatory responses are associated with a greater degree of atherosclerosis in progressive supranuclear palsy

Yi-Xin He
Rui Zhang
Chen Xie
Si-Fan Ji
Wen-Jing Deng
Jun-Fang Teng

Frontiers in Aging Neuroscience

doi 10.3389/fnagi.2025.1608631

2,169 views

Original Research

Published on 08 Aug 2025

Objective assessment of gait and posture symptoms in Parkinson’s disease using wearable sensors and machine learning

Lingyan Ma
Shinuan Lin
Jianing Jin
Zhan Wang
Xuemei Wang
Zhonglue Chen
Yun Ling
Fei Zhang
Kang Ren
Tao Feng

Frontiers in Aging Neuroscience

doi 10.3389/fnagi.2025.1618764

2,557 views

Clinical Trial

Published on 08 Aug 2025

Improvement of neuropsychological and cognitive functions in older adults through transcranial vibroacoustic stimulation: a double blind, randomized, comparative trial

Jang-Han Bae
Jae-Young Ha
Jai Jun Choung
Min-Woo Cho
Byung-In Oh
Kun Ho Lee
Young Chul Youn
SangYun Kim
Dong-Keun Song
Chang-Ho Shin

Frontiers in Aging Neuroscience

doi 10.3389/fnagi.2025.1526088

4,084 views
2 citations

Review

Published on 07 Aug 2025

Curcumin and neuroplasticity: epigenetic mechanisms underlying cognitive enhancement in aging and neurodegenerative disorders

Hao Jiao
Xiuying Wang
Dahui Zhang
Shengxue Zhou
Feng Gao

Frontiers in Aging Neuroscience

doi 10.3389/fnagi.2025.1592280

6,169 views
3 citations

Review

Published on 07 Aug 2025

Acupuncture modulates the microbiota-gut-brain axis: a new strategy for Parkinson’s disease treatment

Zimo Zang
Fang Yang
Liang Qu
Minghui Ge
Liang Tong
Lihui Xue
Xiuye Sun
Ying Hai

Frontiers in Aging Neuroscience

doi 10.3389/fnagi.2025.1640389

4,834 views
4 citations

Original Research

Published on 07 Aug 2025

Latent profile analysis of loneliness among elderly people in the community and its relationship with cognitive function

Lei Yang
Rushi Yang
Tiantian Liu
Jinfeng Wang
Bo Wang
Fengxue Zhao
Yue Zhang
Ping Zhang
Hao Zhang

Frontiers in Aging Neuroscience

doi 10.3389/fnagi.2025.1574095

2,749 views

Original Research

Published on 06 Aug 2025

Neuroinflammation-mediated YKL-40 correlates with tau pathology and predicts longitudinal cognitive impairment and brain atrophy in Alzheimer’s disease, with hypertensive dependency

Ya-Yu Wang
Man Zhang
Shu-Jian Chen
Wei Miao
Zhi-Xin Wang
Ya-Jun Zhou
Si-Qi Yu
Zhong-Wu Sun
Xia Zhou
Xian-Feng Yu

Frontiers in Aging Neuroscience

doi 10.3389/fnagi.2025.1630022

2,947 views
7 citations

Review

Published on 06 Aug 2025

Choline alphoscerate: insights between acquired certainties and future perspectives

Giovanni Biggio
Claudio Mencacci

Frontiers in Aging Neuroscience

doi 10.3389/fnagi.2025.1613566

4,592 views
1 citation

Original Research

Published on 06 Aug 2025

Effect of aspirin use on conversion risk from mild cognitive impairment to Alzheimer’s disease

Bo Kyu Choi
Yeonju Jin
Hokyung Lee
Sung-Woo Kim
Sojeong Park
Ickpyo Hong
Min Seok Baek

Frontiers in Aging Neuroscience

doi 10.3389/fnagi.2025.1603892

3,116 views
2 citations

Original Research

Published on 06 Aug 2025

Effect of aging on the visuomotor control during continuous bimanual movement

Kimia Kiani
Maya Patel
Qiushi Fu

Frontiers in Aging Neuroscience

doi 10.3389/fnagi.2025.1525535

1,349 views

Original Research

Published on 06 Aug 2025

Bioinformatics and experimental validation identify biomarkers for diagnosing Alzheimer’s disease

Hui Liu
Chenye Li
Congchen Zhai
Mei Li
Lan Ma

Frontiers in Aging Neuroscience

doi 10.3389/fnagi.2025.1566929

2,944 views

Original Research

Published on 06 Aug 2025

Ginsenoside Rb1 attenuates neuroflammation via activating Wnt/β-catenin signaling pathway to exert neuroprotective effect on cerebral ischemic-reperfusion injury

Ruo-jing Liu
Xue Zhao
Yi-zhen Zhu
Ling-Ling Fu
Guo Ge
Jun-de Zhu

Frontiers in Aging Neuroscience

doi 10.3389/fnagi.2025.1555067

2,570 views
2 citations

Review

Published on 06 Aug 2025

Advancement in modeling of Alzheimer’s disease: a comprehensive review of preclinical screening platforms

Souvik Adak
Shivam Singh
Ridhi Jain
Abhilasha Tiwari
Binny Singh
Sumit Kumar
Ayushi Dadhwal
Avishek Chakroborty
Ashish Kumar Sharma
Ravindra Pal Singh

Frontiers in Aging Neuroscience

doi 10.3389/fnagi.2025.1646551

4,313 views
2 citations

Original Research

Published on 06 Aug 2025

Hippocampal vascular supply and its mediating role in systemic physiological influences on hippocampal volume

Tae Kim
Javier Rasero
Anna L. Marsland
Mark R. Scudder
Tamer S. Ibrahim
Peter J. Gianaros

Frontiers in Aging Neuroscience

doi 10.3389/fnagi.2025.1590242

2,326 views

Original Research

Published on 05 Aug 2025

Distinct effect of partial sleep deprivation associated with gray matter changes in young and old adults

Xiao Fu
Yanni Shi
Hui Xu
Dongwu Xu

Frontiers in Aging Neuroscience

doi 10.3389/fnagi.2025.1640653

2,156 views

Correction

Published on 05 Aug 2025

Correction: Optineurin overexpression ameliorates neurodegeneration through regulating neuroinflammation and mitochondrial quality in a murine model of amyotrophic lateral sclerosis

Shumin Zhao
Ranran Chen
Yi An
Yali Zhang
Cheng Ma
Ying Gao
Yanchao Lu
Fei Yang
Xue Bai
Jingjing Zhang

Frontiers in Aging Neuroscience

doi 10.3389/fnagi.2025.1670545

1,226 views

Original Research

Published on 05 Aug 2025

Clinical mechanisms of repetitive transcranial magnetic stimulation in improving constipation in Parkinson’s disease patients through the gut-brain axis

Qianlan Bo
Yanmin Li
Xiayue Wang
Huijun Wang
Huimiao Liu

Frontiers in Aging Neuroscience

doi 10.3389/fnagi.2025.1607791

2,639 views
1 citation

Original Research

Published on 04 Aug 2025

Sex differences in the association of cardiometabolic risk scores and blood pressure measurements with white matter hyperintensities in diverse older adults—HABS-HD

Cellas A. Hayes
Raul Vintimilla
Soumilee Chaudhuri
Michelle C. Odden

Frontiers in Aging Neuroscience

doi 10.3389/fnagi.2025.1607646

2,306 views

Review

Published on 04 Aug 2025

Physical activity and neuroinflammation: a bibliometric analysis of research progress and future perspectives

Yeting Zhang
Huangyan Li
Jiangxi Yang
Huan Ma

Frontiers in Aging Neuroscience

doi 10.3389/fnagi.2025.1602724

2,980 views

Original Research

Published on 01 Aug 2025

Uncovering the link between incidental physical activity and inhibition of automatic responses in aging. An ERP study

Javier Sanchez-Lopez
Juan Silva-Pereyra
Sergio Manuel Sánchez-Moguel
Graciela Catalina Alatorre-Cruz
Mauricio González-López
Jorge A Sigg-Alonso
Mariana Pérez-Figueroa
Thalía Fernández

Frontiers in Aging Neuroscience

doi 10.3389/fnagi.2025.1602114

2,098 views

Original Research

Published on 31 Jul 2025

Construction of a predictive model for cognitive impairment among older adults in Northwest China

Yu Wang
Ni Wang
Yanjie Zhao
Xiaoyan Wang
Yuqin Nie
Liping Ding

Frontiers in Aging Neuroscience

doi 10.3389/fnagi.2025.1487838

2,140 views

Original Research

Published on 31 Jul 2025

Difference between Okinawan and Dutch older adults in prefrontal brain activation

Branislava Ćurčić-Blake
Yuko Futenma
Donald Craig Willcox
Parisa Esmaeili Tazangi
Nido Dipo Wardana
Yukihiko Ueda
André Aleman

Frontiers in Aging Neuroscience

doi 10.3389/fnagi.2025.1454068

2,589 views
1 citation

Original Research

Published on 30 Jul 2025

Mechanistic exploration of obesity-related indicators and motor cognitive risk syndrome: a mediated effect based on C-reactive protein triglyceride glucose index

Zhongqiang Guo
Shuang Deng
Li Li
Min Liu

Frontiers in Aging Neuroscience

doi 10.3389/fnagi.2025.1623148

5,828 views

Original Research

Published on 29 Jul 2025

Neuromotor functions across the lifespan: percentiles from 6 to 80 years

Tanja H. Kakebeeke
Jon Caflisch
Aziz Chaouch
Valentin Rousson
Flavia M. Wehrle
Oskar G. Jenni

Frontiers in Aging Neuroscience

doi 10.3389/fnagi.2025.1543408

2,929 views

7,815 Publications

volumes

Volume 17 - 2025

Increased tau-induced inflammatory responses are associated with a greater degree of atherosclerosis in progressive supranuclear palsy

Objective assessment of gait and posture symptoms in Parkinson’s disease using wearable sensors and machine learning

Improvement of neuropsychological and cognitive functions in older adults through transcranial vibroacoustic stimulation: a double blind, randomized, comparative trial

Curcumin and neuroplasticity: epigenetic mechanisms underlying cognitive enhancement in aging and neurodegenerative disorders

Acupuncture modulates the microbiota-gut-brain axis: a new strategy for Parkinson’s disease treatment

Latent profile analysis of loneliness among elderly people in the community and its relationship with cognitive function

Neuroinflammation-mediated YKL-40 correlates with tau pathology and predicts longitudinal cognitive impairment and brain atrophy in Alzheimer’s disease, with hypertensive dependency

Choline alphoscerate: insights between acquired certainties and future perspectives

Effect of aspirin use on conversion risk from mild cognitive impairment to Alzheimer’s disease

Effect of aging on the visuomotor control during continuous bimanual movement

Bioinformatics and experimental validation identify biomarkers for diagnosing Alzheimer’s disease

Ginsenoside Rb1 attenuates neuroflammation via activating Wnt/β-catenin signaling pathway to exert neuroprotective effect on cerebral ischemic-reperfusion injury

Advancement in modeling of Alzheimer’s disease: a comprehensive review of preclinical screening platforms

Hippocampal vascular supply and its mediating role in systemic physiological influences on hippocampal volume

Distinct effect of partial sleep deprivation associated with gray matter changes in young and old adults

Correction: Optineurin overexpression ameliorates neurodegeneration through regulating neuroinflammation and mitochondrial quality in a murine model of amyotrophic lateral sclerosis

Clinical mechanisms of repetitive transcranial magnetic stimulation in improving constipation in Parkinson’s disease patients through the gut-brain axis

Sex differences in the association of cardiometabolic risk scores and blood pressure measurements with white matter hyperintensities in diverse older adults—HABS-HD

Physical activity and neuroinflammation: a bibliometric analysis of research progress and future perspectives

Uncovering the link between incidental physical activity and inhibition of automatic responses in aging. An ERP study

Construction of a predictive model for cognitive impairment among older adults in Northwest China

Difference between Okinawan and Dutch older adults in prefrontal brain activation

Mechanistic exploration of obesity-related indicators and motor cognitive risk syndrome: a mediated effect based on C-reactive protein triglyceride glucose index

Neuromotor functions across the lifespan: percentiles from 6 to 80 years