Frontiers in Aging

Original Research

Published on 24 Sep 2025

Quantifying the relationship between physical performance and mental wellbeing in older adults: a field study

in Healthy Longevity

Róbert Járai
Erzsébet Stephens-Sarlós
Ferenc Ihász
Celal Bulgay
Ádám Balog
Anna Horváth-Pápai
Zoltán Alföldi
Eliza E. Tóth
Angéla Somogyi
Robert Podstawski

Frontiers in Aging

doi 10.3389/fragi.2025.1630343

2,149 views

Original Research

Published on 19 Sep 2025

Accelerated biological aging as potential mediator in the relationship between central obesity and lung cancer risk

in Aging and Cancer

Hongya Liu
Zhihao Deng
Zhongwen Gong
Yangjiao Bai
Yongjia Li
Qing Zhou
Jian Ma
Jing Gao
Xuemei Lian

Frontiers in Aging

doi 10.3389/fragi.2025.1667490

2,089 views

Original Research

Published on 19 Sep 2025

Aging-dependent skin microbiome alterations across body sites in a United Kingdom cohort

in Genetics, Genomics and Epigenomics of Aging

Mary Hannah Swaney
Duncan J. Newman
Junhong Mao
Anthony C. Hilton
Tony Worthington
Min Li

Frontiers in Aging

doi 10.3389/fragi.2025.1644012

3,509 views

Opinion

Published on 18 Sep 2025

Do single people age faster? The answer may lie in sleep

in Healthy Longevity

Jie-Yu Chuang

Frontiers in Aging

doi 10.3389/fragi.2025.1521401

8,209 views

Original Research

Published on 12 Sep 2025

Chromogranin a gene variants influence survival at old age through pleiotropic effects on multiple age-related traits

in Genetics, Genomics and Epigenomics of Aging

Paolina Crocco
Rossella La Grotta
Francesco De Rango
Giuseppe Passarino
Serena Dato
Giuseppina Rose

Frontiers in Aging

doi 10.3389/fragi.2025.1625070

2,108 views

Original Research

Published on 11 Sep 2025

Immune indicators as predictors of cancer-related fatigue: a risk prediction model in pan-cancer patients

in Aging and the Immune System

Guixin He
Ting Ge
Baohui Wang
Jianchun Yu
Wentao Li

Frontiers in Aging

doi 10.3389/fragi.2025.1666116

2,105 views

Original Research

Published on 10 Sep 2025

Physical activity, healthy lifestyle, and subjective wellbeing in people with type 2 diabetes: testing the efficacy of an exercise program

in Interventions in Aging

Luís Cid
Diogo Monteiro
Romeu Mendes
Filipa Cláudio
Teresa Bento
Miguel Jacinto
Nuno Couto
Pedro Duarte-Mendes

Frontiers in Aging

doi 10.3389/fragi.2025.1522615

2,054 views

Original Research

Published on 09 Sep 2025

Reversal of perturbed DNA damage response and HIV latency by a histone methyltransferase inhibitor in virally suppressed individuals living with HIV

in Aging and the Immune System

Pragati Chavan
Sathi Koar
Rohini Bingewar
Anuja Sonawane
Jyoti Sawant
Pallavi Shidhaye
Amrita Rao
Rajani Bagul
Ujjwala Ghule
Sunita Kumbhar

Frontiers in Aging

doi 10.3389/fragi.2025.1658506

1,873 views

Original Research

Published on 05 Sep 2025

Impact of a four-domain intrinsic capacity measure on falls: findings from the EPOSA study

in Healthy Longevity

Chiara Ceolin
Paola Siviero
Federica Limongi
Marianna Noale
Giuseppe Sergi
Stefania Maggi
the EPOSA Research Group

Frontiers in Aging

doi 10.3389/fragi.2025.1645712

7,769 views
3 citations

Clinical Trial

Published on 04 Sep 2025

Effects of a digital visual art learning intervention in healthy older adults: a pilot randomized controlled trial

in Interventions in Aging

Akari Uno
Ryan Browne
Takamitsu Shinada
Michio Takahashi
Keishi Soga
Yegang Du
Fumihira Abiko
Yasuyuki Taki

Frontiers in Aging

doi 10.3389/fragi.2025.1635789

2,795 views
1 citation

Original Research

Published on 03 Sep 2025

Surrogate insulin resistance indices are associated with left atrial thrombus in patients with nonvalvular atrial fibrillation

in Healthy Longevity

You Zhou
Xuewen Song
Jifang Ma
Xianqing Wang
Haixia Fu

Frontiers in Aging

doi 10.3389/fragi.2025.1571609

7,749 views

Methods

Published on 19 Aug 2025

Prevention in nursing care: a study protocol of a cluster-randomized controlled trial on the effects of physical exercise and environmental interventions on physical activity behavior and physical functioning in nursing home residents (PROGRESS study)

in Interventions in Aging

Vera Belkin
Tanja I. Janssen
Julian Rudisch
Bettina Wollesen
Claudia Voelcker-Rehage

Frontiers in Aging

doi 10.3389/fragi.2025.1466315

2,541 views

Original Research

Published on 18 Aug 2025

Risk factors and predictors of contralateral hip fracture after surgical treatment in elderly patients

in Musculoskeletal Aging

Huan Yang
Yusong Yuan
Ruidong Ge
Lei Shi
Fangda Si
Ying Chen

Frontiers in Aging

doi 10.3389/fragi.2025.1633184

1,805 views

Opinion

Published on 18 Aug 2025

The human biological clock and aging—a comprehensive approach integrating reductionism, holism, and geromedicine for proactive healthspan strategies

in Genetics, Genomics and Epigenomics of Aging

Teow J. Phua

Frontiers in Aging

doi 10.3389/fragi.2025.1658952

4,102 views
1 citation

Clinical Trial

Published on 18 Aug 2025

Effects of combined aerobic-resistance training on health-related quality of life and stress in sedentary adults

in Interventions in Aging

Fernanda M. Silva
José P. Ferreira
Ana M. Teixeira
Alain Massart
Pedro Duarte-Mendes

Frontiers in Aging

doi 10.3389/fragi.2025.1603635

3,794 views
1 citation

Original Research

Published on 14 Aug 2025

Effects of high-intensity interval training on physical and cognitive function in middle-aged male mice

in Interventions in Aging

Justin C. Stephenson
Tuan D. Tran
Ted G. Graber

Frontiers in Aging

doi 10.3389/fragi.2025.1589730

3,178 views

Editorial

Published on 14 Aug 2025

Editorial: Interaction between genes and the environment in skin aging

in Genetics, Genomics and Epigenomics of Aging

Xiaolei Ding
Sigrid Le Clerc

Frontiers in Aging

doi 10.3389/fragi.2025.1671721

1,922 views
1 citation

Original Research

Published on 07 Aug 2025

Better olfaction was associated with lower healthcare expenditure among physically independent Japanese community-dwelling older adults: the Yanai study

in Healthy Longevity

Yujiro Kose
Yoichi Hatamoto
Rie Tomiga-Takae
Yukari Kimuro
Ryo Aoyagi
Hikaru Kawasaki
Takaaki Komiyama
Mamiko Ichikawa
Katsutoyo Fujiyama
Yoshiro Murata

Frontiers in Aging

doi 10.3389/fragi.2025.1592838

3,922 views

Original Research

Published on 06 Aug 2025

Adapting to vision changes: nighttime driving experiences of older adults

in Interventions in Aging

Christopher R.M. Rundus
Dominique Rose
Fangda Zhang
Sean Brown
Jingzhen Yang

Frontiers in Aging

doi 10.3389/fragi.2025.1563917

1,636 views

Review

Published on 05 Aug 2025

Pathogenic synergy: dysfunctional mitochondria and neuroinflammation in neurodegenerative diseases associated with aging

in Aging, Metabolism and Redox Biology

Shalini Mani
Samiksha Wasnik
Chesta Shandilya
Vidushi Srivastava
Saboor Khan
Keshav K. Singh

Frontiers in Aging

doi 10.3389/fragi.2025.1615764

4,913 views
6 citations

Brief Research Report

Published on 05 Aug 2025

Association between care complexity individual factors and older inpatients with COVID-19: a cross-sectional study

in Healthy Longevity

Jordi Adamuz
Julia González-Vaca
Maribel González-Samartino
María-Magdalena López-Jiménez
Andrea Urbina
Oliver Polushkina-Merchanskaya
Sergio Alonso-Fernández
Silvia Esteban-Sepúlveda
Sergio Barrientos-Trigo
Maria-Eulàlia Juvé-Udina

Frontiers in Aging

doi 10.3389/fragi.2025.1524849

3,893 views

Original Research

Published on 31 Jul 2025

CX3CR1 upregulation modulates microglial activation and preserves synapses in the hippocampus and frontal cortex of middle-aged mice

in Molecular Mechanisms of Aging

Jinfeng Liu
Zhongqing Sun
Xin Liu
Kin Chiu
Lan Ma
Jiantao Wang

Frontiers in Aging

doi 10.3389/fragi.2025.1549848

2,618 views
3 citations

Review

Published on 31 Jul 2025

Advances in the application of multi-omics analysis in skin aging

in Aging, Metabolism and Redox Biology

Boquan Long
Weitian Pan
Shuozhong Wu
Qianye Nong
Wenhui Li
Siqi Chen
Hongwei Guo

Frontiers in Aging

doi 10.3389/fragi.2025.1596050

4,539 views
1 citation

Correction

Published on 31 Jul 2025

Correction: Age- and sex-related development of osteosarcopenia in the aging Octodon degus rodent model

in Musculoskeletal Aging

Pablo Gallo-Soljancic
Maria Egle De Stefano
Ana-Maria Lucas-Ochoa
Consuelo Sánchez-Rodrigo
Lorena Cuenca-Bermejo
Ana-María González-Cuello
Emiliano Fernández-Villalba
Maria-Trinidad Herrero

Frontiers in Aging

doi 10.3389/fragi.2025.1669031

1,619 views

671 articles

articles

Quantifying the relationship between physical performance and mental wellbeing in older adults: a field study

Accelerated biological aging as potential mediator in the relationship between central obesity and lung cancer risk

Aging-dependent skin microbiome alterations across body sites in a United Kingdom cohort

Do single people age faster? The answer may lie in sleep

Chromogranin a gene variants influence survival at old age through pleiotropic effects on multiple age-related traits

Immune indicators as predictors of cancer-related fatigue: a risk prediction model in pan-cancer patients

Physical activity, healthy lifestyle, and subjective wellbeing in people with type 2 diabetes: testing the efficacy of an exercise program

Reversal of perturbed DNA damage response and HIV latency by a histone methyltransferase inhibitor in virally suppressed individuals living with HIV

Impact of a four-domain intrinsic capacity measure on falls: findings from the EPOSA study

Effects of a digital visual art learning intervention in healthy older adults: a pilot randomized controlled trial

Surrogate insulin resistance indices are associated with left atrial thrombus in patients with nonvalvular atrial fibrillation

Prevention in nursing care: a study protocol of a cluster-randomized controlled trial on the effects of physical exercise and environmental interventions on physical activity behavior and physical functioning in nursing home residents (PROGRESS study)

Risk factors and predictors of contralateral hip fracture after surgical treatment in elderly patients

The human biological clock and aging—a comprehensive approach integrating reductionism, holism, and geromedicine for proactive healthspan strategies

Effects of combined aerobic-resistance training on health-related quality of life and stress in sedentary adults

Effects of high-intensity interval training on physical and cognitive function in middle-aged male mice

Editorial: Interaction between genes and the environment in skin aging

Better olfaction was associated with lower healthcare expenditure among physically independent Japanese community-dwelling older adults: the Yanai study

Adapting to vision changes: nighttime driving experiences of older adults

Pathogenic synergy: dysfunctional mitochondria and neuroinflammation in neurodegenerative diseases associated with aging

Association between care complexity individual factors and older inpatients with COVID-19: a cross-sectional study

CX3CR1 upregulation modulates microglial activation and preserves synapses in the hippocampus and frontal cortex of middle-aged mice

Advances in the application of multi-omics analysis in skin aging

Correction: Age- and sex-related development of osteosarcopenia in the aging Octodon degus rodent model