Frontiers in Bioengineering and Biotechnology | Tissue Engineering and Regenerative Medicine

Original Research

Published on 08 Aug 2025

Laminin-derived peptide drives the cardiomyogenic potential and cardiac cells functionality

in Tissue Engineering and Regenerative Medicine

Simona Casarella
Federica Ferla
Dalila Di Francesco
Veronica Pagani
Carolina Di Varsavia
Irene Regano
Francesca Boccafoschi

Frontiers in Bioengineering and Biotechnology

doi 10.3389/fbioe.2025.1629412

236 views

Review

Published on 08 Aug 2025

Menstrual blood-derived mesenchymal stromal cell extracellular vesicles – a potential tool for tissue regeneration and disease detection

in Tissue Engineering and Regenerative Medicine

Raminta Vaiciuleviciute
Jolita Pachaleva
Eiva Bernotiene
Gabija Kugaudaite
Ignas Lebedis
Edvinas Krugly
Ilona Uzieliene

Frontiers in Bioengineering and Biotechnology

doi 10.3389/fbioe.2025.1643408

220 views

Original Research

Published on 08 Aug 2025

Innate immune pathway activation to modulate mesenchymal stromal cell (MSC) interactions with synovium and cartilage

in Tissue Engineering and Regenerative Medicine

Peter Linde
Lyndah Chow
Isabella Sabino
Zoë Williams
Renata Impastato
Steven Dow
Lynn Pezzanite

Frontiers in Bioengineering and Biotechnology

doi 10.3389/fbioe.2025.1605148

240 views

Original Research

Published on 08 Aug 2025

Connexin 43 suppression enhances contractile force in human iPSC-derived cardiac tissues

in Tissue Engineering and Regenerative Medicine

Takuma Takada
Katsuhisa Matsuura
Tatsuro Iida
Toshiharu Koike
Hidekazu Sekine
Yuhei Higashi
Tsukasa Hara
Daisuke Sasaki
Kyohei Fujita
Yuto Hinata

Frontiers in Bioengineering and Biotechnology

doi 10.3389/fbioe.2025.1615953

326 views

Original Research

Published on 04 Aug 2025

Isolation, characterization, and vascular potential of porcine cells in a three-dimensional decellularized liver matrix model

in Tissue Engineering and Regenerative Medicine

Sara Morini
Sandra Melitón Barbancho
Álvaro Blanes Rodríguez
Iris Pla-Palacín
Pilar Sainz-Arnal
Natalia Sánchez-Romero
Maria Victoria Falceto
Olga Mitjana
Antonio Romero
Marcela Del Rio-Nechaevsky

Frontiers in Bioengineering and Biotechnology

doi 10.3389/fbioe.2025.1625999

691 views

Original Research

Published on 04 Aug 2025

Challenges and limitations in developing of a new maxillary standardized rat alveolar bone defect model to study bone regenerative approaches in oral and maxillofacial surgery

in Tissue Engineering and Regenerative Medicine

Naïma Ahmed Omar
Jéssica Roque
Céline Bergeaut
Laurent Bidault
Joëlle Amédée
Didier Letourneur
Jean-Christophe Fricain
Mathilde Fenelon

Frontiers in Bioengineering and Biotechnology

doi 10.3389/fbioe.2025.1494352

502 views

Original Research

Accepted on 01 Aug 2025

Dynamic male mouse gut microbiota signature linked to improved wound healing of a novel salecan hydrogel dressing

in Tissue Engineering and Regenerative Medicine

Guangping Luo
Tongtong Zhang
Yanan Jiang
Yuan Qin
Pengfei Chen
Junqing Hu

Frontiers in Bioengineering and Biotechnology

doi 10.3389/fbioe.2025.1584976

242 views

Original Research

Accepted on 31 Jul 2025

Novel Platelet Rich Plasma/ Hyaluronic acid lyophilized formulations for wound healing applications

in Tissue Engineering and Regenerative Medicine

Antonella D'Agostino
Maria d'Agostino
Marta Nardini
Anita Muraglia
CELESTE DI MEO
Maddalena Mastrogiacomo
Chiara Schiraldi

Frontiers in Bioengineering and Biotechnology

doi 10.3389/fbioe.2025.1619633

214 views

Original Research

Accepted on 31 Jul 2025

EP4 receptor stimulation in combination with core decompression therapy enhanced bone regeneration in a canine model of osteonecrosis of femoral head

in Tissue Engineering and Regenerative Medicine

Kyoko Hirano
Takaki Miyagawa
Masahiro Nishida
Haruhiko Akiyama

Frontiers in Bioengineering and Biotechnology

doi 10.3389/fbioe.2025.1622918

170 views

Review

Published on 30 Jul 2025

From bench to bedside: translating mesenchymal stem cell therapies through preclinical and clinical evidence

in Tissue Engineering and Regenerative Medicine

Jai Chand Patel
Meenakshi Shukla
Manish Shukla

Frontiers in Bioengineering and Biotechnology

doi 10.3389/fbioe.2025.1639439

981 views

Hypothesis and Theory

Accepted on 29 Jul 2025

Platelet-rich plasma may accelerate diabetic wound healing by modulating epithelial/endothelial-mesenchymal transition through inhibiting reactive oxygen species-mediated oxidative stress

in Tissue Engineering and Regenerative Medicine

Youan Li
Biao Cheng
JU TIAN

Frontiers in Bioengineering and Biotechnology

doi 10.3389/fbioe.2025.1623780

289 views

Original Research

Published on 29 Jul 2025

Bioadhesive chitosan hydrogel with dynamic covalent bonds and sustained kartogenin release for endogenous cartilage regeneration

in Tissue Engineering and Regenerative Medicine

Mingjing Li
Fan Li
Jian Xu
Li Zhu
Jiang Xiang
Chunquan Zhu
Zonghui Dai
Sen Tang
Fucheng Ouyang
Jiawen Yu

Frontiers in Bioengineering and Biotechnology

doi 10.3389/fbioe.2025.1606726

695 views

Original Research

Published on 28 Jul 2025

Restoration of tendon repair microenvironment by grapefruit exosome-loaded microneedle system for tendinopathy therapy

in Tissue Engineering and Regenerative Medicine

Yuan Zhang
Ruiyang Zhang
Ti Zhang
Yuhao Mu
Talante Juma
Xu Li
Hao Li
Quanyi Guo
Yongping Cao

Frontiers in Bioengineering and Biotechnology

doi 10.3389/fbioe.2025.1615650

734 views

Original Research

Published on 23 Jul 2025

3D-printed polycaprolactone combined with cartilage acellular matrix tissue engineered cartilage scaffold manufactured by low-temperature deposition manufacturing

in Tissue Engineering and Regenerative Medicine

Zhen Song
Xulong Zhang
Yihao Xu
Jingyuan Ji
Wei Sun
Fei Fan
Jianjun You
Yuan Pang

Frontiers in Bioengineering and Biotechnology

doi 10.3389/fbioe.2025.1604515

625 views

Review

Published on 23 Jul 2025

Physical cues in biomaterials modulate macrophage polarization for bone regeneration: a review

in Tissue Engineering and Regenerative Medicine

Tianxiao Yang
Zhurun Fang
Jin Zhang
Shengnai Zheng

Frontiers in Bioengineering and Biotechnology

doi 10.3389/fbioe.2025.1640560

734 views

Original Research

Accepted on 21 Jul 2025

Electrospun textiles from Decellularized Bovine Pericardium and Polyvinyl alcohol (PVA) supporting blood coagulation: Innovative approach in biomaterials for research purposes

in Tissue Engineering and Regenerative Medicine

Luca Di Nunno
Veronica Pagani
Elena Canciani
Gerardina Ruocco
MATTIA SPEDICATI
MARIA TALMON
Luca Fusaro
Dalila Di Francesco
Simona Casarella
Manuela Rizzi

Frontiers in Bioengineering and Biotechnology

doi 10.3389/fbioe.2025.1539759

209 views