Frontiers in Cell and Developmental Biology

Original Research

Accepted on 04 Jul 2025

Smarce1 fine-tunes Cardiomyocyte Proliferation in the Embryonic Zebrafish Heart

in Embryonic Development

Deung-Dae Park
Tillman Dahme
Leonie Krieg
Steffen Just
Wolfgang Rottbauer

Frontiers in Cell and Developmental Biology

doi 10.3389/fcell.2025.1636944

192 views

Original Research

Accepted on 04 Jul 2025

Exploring the Protective Mechanisms of the Yunpi Jiedu Tongluo Qushi Decoction on Methotrexate-Induced Reproductive Damage in Male Rats Based on Nrf2/HO-1 Signaling Pathway

in Cell Death and Survival

WU Chen
Min Chen
Li Dianming
Wei-Man Shi
Min Zhang
Zhi-Yu Li
Lin Huang
Chengping Wen
Qiao Wang

Frontiers in Cell and Developmental Biology

doi 10.3389/fcell.2025.1626955

167 views

Brief Research Report

Accepted on 04 Jul 2025

Haploinsufficiency of ABL1 is associated with dominant isolated omphalocele

in Embryonic Development

Caroline M. Kolvenbach
Öznur Yilmaz
Filipa M. Lopes
Jeshurun C Kalanithy
Katharina Lemberg
Vineeta Sharma
Amar Majmundar
Matthias Geyer
Adrian S Woolf
Friedhelm Hildebrandt

Frontiers in Cell and Developmental Biology

doi 10.3389/fcell.2025.1630894

190 views

Original Research

Published on 04 Jul 2025

Integration of chromosome conformation and gene expression networks reveals regulatory mechanisms in triple negative breast cancer

in Epigenomics and Epigenetics

Helena Reyes-Gopar
Keila Adonai Pérez-Fuentes
Matthew L. Bendall
Enrique Hernández-Lemus

Frontiers in Cell and Developmental Biology

doi 10.3389/fcell.2025.1597245

720 views

Original Research

Published on 04 Jul 2025

VE-PTP controls a fluid shear stress set point that governs cell morphological responses through Tie-2

in Cell Adhesion and Migration

Keisuke Shirakura
Mana Ghanbarpour Houshangi
Kevin G. Peters
Dietmar Vestweber

Frontiers in Cell and Developmental Biology

doi 10.3389/fcell.2025.1603517

590 views

Review

Published on 04 Jul 2025

Involvement of role of HMGB1-NLRP3 pathway in systemic disorders

in Signaling

Lei Yang
Xue Li
Xiaoming Zhu
Futao Ge
Yuantao Wang

Frontiers in Cell and Developmental Biology

doi 10.3389/fcell.2025.1600596

495 views

Original Research

Published on 03 Jul 2025

Age-dependent integration of cortical progenitors transplanted at CSF-neurogenic niche interface

in Stem Cell Research

Gretchen Greene
Nikorn Pothayee
Jahandar Jahanipour
Hyesoo Jie
Jung-Hwa Tao-Cheng
Emily Petrus
Dragan Maric
Alan P. Koretsky

Frontiers in Cell and Developmental Biology

doi 10.3389/fcell.2025.1577045

611 views

Original Research

Published on 03 Jul 2025

Selective blockade of acid-sensing ion channel 1a can provide substantial hippocampal neuroprotection

in Cell Death and Survival

Jiaai Li
Yu Cheng
Di Ma
Guangjian Li
Weixuan Zhao
Ting Jiang
Hongmei Meng

Frontiers in Cell and Developmental Biology

doi 10.3389/fcell.2025.1582970

648 views

Original Research

Published on 03 Jul 2025

PD-L1 expression predicts the efficacy of PD-1 blockade plus chemotherapy versus chemotherapy alone in treatment-naïve advanced or metastatic gastric cancer: a pooled analysis of reconstructed individual patient-level data from two randomized trials

in Cancer Cell Biology

Wei Zhou
Zeng-Zhi Cai
Zhuolin Fan
Xu Zheng
Yu-Tong Chen

Frontiers in Cell and Developmental Biology

doi 10.3389/fcell.2025.1636288

592 views

Original Research

Published on 03 Jul 2025

Temporal dynamics of gene and protein signatures following volumetric muscle loss

in Molecular and Cellular Pathology

Ishita Jain
Beu P. Oropeza
Caroline Hu
Gladys Chiang
Sree Aravindan
Renato Reyes
Daniel Yuhang Li
Paul Cheng
Ngan F. Huang

Frontiers in Cell and Developmental Biology

doi 10.3389/fcell.2025.1606609

610 views

Review

Published on 03 Jul 2025

How the chromatin landscape influences nuclear morphology

in Morphogenesis and Patterning

Sourabh Sengupta
Haritha Prabha
Daniel L. Levy

Frontiers in Cell and Developmental Biology

doi 10.3389/fcell.2025.1634252

658 views

Original Research

Accepted on 02 Jul 2025

Automated Detection of Diabetic Retinopathy Lesions in Ultra-Widefield fundus Images Using an Attention-Augmented YOLOv8 Framework

in Molecular and Cellular Pathology

Lei-Si Hu
Jie Wang
Ming-Heng Zhang
Hai-Yu Huang

Frontiers in Cell and Developmental Biology

doi 10.3389/fcell.2025.1608580

140 views

Review

Accepted on 02 Jul 2025

The Multifaceted Impact of Physical Exercise on FoxO Signaling Pathways

in Signaling

Wei Liu
Pengjun Meng
Zhi Li
Yifei Shen
Xin Meng
Shen Jin
MengDi Hu

Frontiers in Cell and Developmental Biology

doi 10.3389/fcell.2025.1614732

129 views

Original Research

Accepted on 02 Jul 2025

TRABD maintains mitochondrial homeostasis and protects against ischemia reperfusion-induced renal tubular injury

in Signaling

Wenqi Duan
Wenye Wu
Cui Yang
Mei Zhang
Xuemei Li
Wenmin Tian
Yang Chen
Xinjun Zhang

Frontiers in Cell and Developmental Biology

doi 10.3389/fcell.2025.1619339

211 views

Original Research

Published on 02 Jul 2025

Overexpression of GDF15 protects kidneys from ischemia reperfusion injury and affects circular RNA expression

in Molecular and Cellular Pathology

Cuilin Zhu
Qing Liu
Yale Su
Yixin Zhang
Aanal Patel
Adam Greasley
Jifu Jiang
Douglas Quan
Weiping Min
Kexiang Liu

Frontiers in Cell and Developmental Biology

doi 10.3389/fcell.2025.1577625

704 views

Original Research

Published on 02 Jul 2025

CKAP4 and PLOD2 as novel prognostic biomarkers in hepatocellular carcinoma: a proteomics-driven risk stratification model

in Cancer Cell Biology

Qiulong Lu
Zhao Cao
Yueting Xiong
Junqiang Huang
Huan Zeng
Zhijian Chen
You Shu
Yahan Tan
Xiaoling Long
Xiaohui Liu

Frontiers in Cell and Developmental Biology

doi 10.3389/fcell.2025.1577161

765 views