Frontiers in Cell and Developmental Biology | Molecular and Cellular Pathology

Original Research

Published on 30 Dec 2025

Fibroblast growth factor 9 activates fibroblast activation and drives the progress of shoulder stiffness

in Molecular and Cellular Pathology

Jian Xu
Weihan Yu
Yunkang Kang
Dongqiang Yang
Yanlong Liu
Wenzhi Bi
Haiyang Yu
Beijie Qi
Biao Guo

Frontiers in Cell and Developmental Biology

doi 10.3389/fcell.2025.1731453

850 views

Original Research

Published on 29 Dec 2025

Integration of peripheral blood-based systemic inflammatory indices and retinal imaging using interpretable machine learning for predicting anti-VEGF treatment response in macular edema secondary to retinal vein occlusion

in Molecular and Cellular Pathology

Jiajun Li
Yao Lu
Qianzi Jin
Siqi Wu
Xiangzhong Xu
Qin Jiang
Keran Li

Frontiers in Cell and Developmental Biology

doi 10.3389/fcell.2025.1732963

1,126 views

Original Research

Published on 19 Dec 2025

Association of fibronectin 1 deregulation with tyrosine kinase inhibitor resistance in chronic myeloid leukemia

in Molecular and Cellular Pathology

Lina Tiedemann
Sivahari Prasad Gorantla
Philine Ahlf
Lucie Sophie Schmidt
Christiane Pott
Merit Litterst
Vicki Waetzig
Inga Nagel
Johanna Ruemenapp
Nikolas von Bubnoff

Frontiers in Cell and Developmental Biology

doi 10.3389/fcell.2025.1725857

1,124 views

Review

Published on 18 Dec 2025

The role of ADAR1 in human pathophysiology

in Molecular and Cellular Pathology

Jiahao Li
Yushan Xiao
Xiaofeng Li
Yan Dai

Frontiers in Cell and Developmental Biology

doi 10.3389/fcell.2025.1672970

1,589 views

Review

Published on 17 Dec 2025

The role of MMPs in intracerebral hemorrhage

in Molecular and Cellular Pathology

Xiaofei Guan
Meiren Li
Huimin Li
Zeqin Guo
Muhammad Saad Ullah
Xiaoqun Liu
Moxin Wu
Wenmin Yu

Frontiers in Cell and Developmental Biology

doi 10.3389/fcell.2025.1667228

1,832 views

Original Research

Published on 16 Dec 2025

Microglia response and function in a chronic model of photoreceptor damage

in Molecular and Cellular Pathology

Deepa Raghavan
Olivia Jeakle
Yasmeen Berry
Majd Victor
Ryan Thummel

Frontiers in Cell and Developmental Biology

doi 10.3389/fcell.2025.1699271

1,537 views

Original Research

Published on 16 Dec 2025

Image-text guided fundus vessel segmentation via attention mechanism and gated residual learning

in Molecular and Cellular Pathology

Jianguo Xu
Qingyou Liu
Jianxin Shen
Rong Tan
Sukun Tian
Wei Chi
Weihua Yang

Frontiers in Cell and Developmental Biology

doi 10.3389/fcell.2025.1710343

907 views

Original Research

Published on 12 Dec 2025

Effects of high-altitude environments on intervertebral disc degeneration and transcriptome profiling of the nucleus pulposus

in Molecular and Cellular Pathology

Jiawei Fu
Rong Tang
Tianfei Ran
Yue Zhou
Bo Huang

Frontiers in Cell and Developmental Biology

doi 10.3389/fcell.2025.1709844

1,182 views

Original Research

Published on 11 Dec 2025

Knowledge-enhanced AI drives diagnosis of multiple retinal diseases in fundus fluorescein angiography

in Molecular and Cellular Pathology

Ming-Ming Duan
Hui Qi
Xiang Tu

Frontiers in Cell and Developmental Biology

doi 10.3389/fcell.2025.1703606

826 views

Original Research

Published on 11 Dec 2025

Molecular insights into Atorvastatin’s role in delaying intervertebral disc degeneration

in Molecular and Cellular Pathology

Yupeng Li
Linghao Wang
Xingjie Wang
Kang Li
Qian Wang
Kai Gao
Cunxin Zhang
Chaoliang Lv

Frontiers in Cell and Developmental Biology

doi 10.3389/fcell.2025.1693951

1,016 views

Original Research

Published on 11 Dec 2025

Mathematical modeling reveals cell differentiation processes and progenitor kinetics necessary for proper nephrogenesis

in Molecular and Cellular Pathology

Matthew R. Hawkins
Stuart E. Jones
Hannah M. Wesselman
Cecilia Cesa
Joshua Moeller
Rebecca A. Wingert

Frontiers in Cell and Developmental Biology

doi 10.3389/fcell.2025.1695380

944 views

Review

Published on 10 Dec 2025

Sidedness matters: single-cell perspectives on left- and right-sided colorectal cancer

in Molecular and Cellular Pathology

Maria Yanova
Diana Maltseva
Alexander Tonevitsky

Frontiers in Cell and Developmental Biology

doi 10.3389/fcell.2025.1720996

1,748 views

Original Research

Published on 04 Dec 2025

Quantitative analysis of the effect of ocular rotation on postoperative residual astigmatism in small incision lenticule extraction for myopia correction

in Molecular and Cellular Pathology

Caiyu Liu
Xiaoying Xu
Hao Gu
Chi Wang
Lu Lu
Kaizhen Ye
Yan Zheng
Haiyan Wang
Wei Chen
Meiyan Li

Frontiers in Cell and Developmental Biology

doi 10.3389/fcell.2025.1695775

1,087 views

Original Research

Published on 04 Dec 2025

Loss of a primary cilia protein ARL13B promotes TGFβ-1 induced EMT of RPE in proliferative vitreoretinopathy via increasing Smad3 expression

in Molecular and Cellular Pathology

Wenjun Sui
Xinqi Ma
Yajun Gong
Kairui Qiu
Miner Yuan
Keli Mao
Xiaobing Qian
Jieting Zeng
Yujie Li
Bingsheng Lou

Frontiers in Cell and Developmental Biology

doi 10.3389/fcell.2025.1661658

1,358 views

Original Research

Published on 03 Dec 2025

TNF-α exacerbates calcium influx via voltage-gated calcium channels in breast cancer cells: a nanoscale multimodal AFM study

in Molecular and Cellular Pathology

Zhongwei Wang
Qianhui Xu
Huaiwei Zhang
Rongrong Feng
Junmei Chen
Jinsong Wei
Haijian Zhong
Weidong Zhao

Frontiers in Cell and Developmental Biology

doi 10.3389/fcell.2025.1633976

1,154 views

Original Research

Published on 02 Dec 2025

Evaluating the competence of large language models in ophthalmology clinical practice: a multi-scenario quantitative study

in Molecular and Cellular Pathology

Mu-Yang Wei
Yu-Lin Li
Shu-Yan Liu
Guang-Yu Li

Frontiers in Cell and Developmental Biology

doi 10.3389/fcell.2025.1704762

1,132 views

Editorial

Published on 02 Dec 2025

Editorial: Cardiac fibroblasts: from development to disease

in Molecular and Cellular Pathology

Silvia C. Hernandez
Thomas Moore-Morris
Adrian Ruiz-Villalba

Frontiers in Cell and Developmental Biology

doi 10.3389/fcell.2025.1736508

675 views

Original Research

Published on 27 Nov 2025

Leukocyte mRNA sequencing reveals unfolded protein response activation in severe heat stroke in Japan

in Molecular and Cellular Pathology

Yusuke Nomura
Sayaka Oda
Hisatake Matsumoto
Yuki Togami
Junya Shimazaki
Daisuke Okuzaki
Hiroshi Ogura
Jun Oda

Frontiers in Cell and Developmental Biology

doi 10.3389/fcell.2025.1640477

1,163 views

Original Research

Published on 27 Nov 2025

Antiphotoaging effects of a group of antioxidant peptides through downregulating matrix metalloproteinases and inflammation factors

in Molecular and Cellular Pathology

Yichao Huang
Juxingsi Song
Zhengbang Wang
Shaoqian Zhu
Yanan Hu
Xinyue Gan
Sai Luo
Qian He
Liming Zhang
Qianqian Wang

Frontiers in Cell and Developmental Biology

doi 10.3389/fcell.2025.1649391

1,155 views

Original Research

Published on 26 Nov 2025

Enhancing preoperative HER2 status classification of invasive breast cancers using machine learning models based on clinicopathological and MRI features: a multicenter study

in Molecular and Cellular Pathology

Suhong Zhao
Zhaohua Li
Yanan Wang
Fang Zhao
Peipei Chen
Guodong Pang

Frontiers in Cell and Developmental Biology

doi 10.3389/fcell.2025.1669651

977 views

Mini Review

Published on 26 Nov 2025

Targeting endothelial cells: the pathological mechanisms and therapeutic innovations in pulmonary arterial hypertension

in Molecular and Cellular Pathology

Tianfei Fan
Longji Li
Yao Wang
Meng Lin
Fengbo Wu

Frontiers in Cell and Developmental Biology

doi 10.3389/fcell.2025.1690124

1,724 views
2 citations

Original Research

Published on 24 Nov 2025

Astrocytic gatekeeping of neural circuitry and synaptic balance in an autism mouse model: mechanistic insights beyond Gryllus bimaculatus extract-derived therapy

in Molecular and Cellular Pathology

Haesung Lee
Ngoc Buu Tran
Sook-Jeong Lee

Frontiers in Cell and Developmental Biology

doi 10.3389/fcell.2025.1677851

1,193 views

Original Research

Published on 20 Nov 2025

Acetylcholine in the gingival epithelium drives the pathogenesis of periodontitis

in Molecular and Cellular Pathology

Shihan Xu
Jiaxin Guo
Shiwen Yang
Bin Cheng
Juan Xia

Frontiers in Cell and Developmental Biology

doi 10.3389/fcell.2025.1701252

1,258 views

Mini Review

Published on 20 Nov 2025

Dendrite glia interactions: lessons from the C. elegans amphid sense organ

in Molecular and Cellular Pathology

Katherine C. Varandas

Frontiers in Cell and Developmental Biology

doi 10.3389/fcell.2025.1715817

1,938 views

2,492 articles

articles

Fibroblast growth factor 9 activates fibroblast activation and drives the progress of shoulder stiffness

Integration of peripheral blood-based systemic inflammatory indices and retinal imaging using interpretable machine learning for predicting anti-VEGF treatment response in macular edema secondary to retinal vein occlusion

Association of fibronectin 1 deregulation with tyrosine kinase inhibitor resistance in chronic myeloid leukemia

The role of ADAR1 in human pathophysiology

The role of MMPs in intracerebral hemorrhage

Microglia response and function in a chronic model of photoreceptor damage

Image-text guided fundus vessel segmentation via attention mechanism and gated residual learning

Effects of high-altitude environments on intervertebral disc degeneration and transcriptome profiling of the nucleus pulposus

Knowledge-enhanced AI drives diagnosis of multiple retinal diseases in fundus fluorescein angiography

Molecular insights into Atorvastatin’s role in delaying intervertebral disc degeneration

Mathematical modeling reveals cell differentiation processes and progenitor kinetics necessary for proper nephrogenesis

Sidedness matters: single-cell perspectives on left- and right-sided colorectal cancer

Quantitative analysis of the effect of ocular rotation on postoperative residual astigmatism in small incision lenticule extraction for myopia correction

Loss of a primary cilia protein ARL13B promotes TGFβ-1 induced EMT of RPE in proliferative vitreoretinopathy via increasing Smad3 expression

TNF-α exacerbates calcium influx via voltage-gated calcium channels in breast cancer cells: a nanoscale multimodal AFM study

Evaluating the competence of large language models in ophthalmology clinical practice: a multi-scenario quantitative study

Editorial: Cardiac fibroblasts: from development to disease

Leukocyte mRNA sequencing reveals unfolded protein response activation in severe heat stroke in Japan

Antiphotoaging effects of a group of antioxidant peptides through downregulating matrix metalloproteinases and inflammation factors

Enhancing preoperative HER2 status classification of invasive breast cancers using machine learning models based on clinicopathological and MRI features: a multicenter study

Targeting endothelial cells: the pathological mechanisms and therapeutic innovations in pulmonary arterial hypertension

Astrocytic gatekeeping of neural circuitry and synaptic balance in an autism mouse model: mechanistic insights beyond Gryllus bimaculatus extract-derived therapy

Acetylcholine in the gingival epithelium drives the pathogenesis of periodontitis

Dendrite glia interactions: lessons from the C. elegans amphid sense organ