Frontiers in Cellular and Infection Microbiology | Adaptive Immunity in Infection

Original Research

Accepted on 09 Oct 2025

LYMPHOCYTE LOSS AND PLASMACYTOSIS ARE ASSOCIATED WITH IL-6-AND TNF-PRODUCING CELLS IN THE SPLEENS OF FATAL COVID-19 CASES

in Adaptive immunity in infection

Bianca Ramos Mesquita
Lilian Verena da Silva Carvalho
Leonardo Cardoso Gomes Baqueiro
Reginaldo Brito
Luma Bahia Figueiredo Pinto
Erina Masayo Alves Hassegawa
Jonathan Luís Magalhães Fontes
Claudio Pereira Figueira
Eraldo Salustiano Moura
Maria Brandão Tavares

Frontiers in Cellular and Infection Microbiology

doi 10.3389/fcimb.2025.1645378

Original Research

Accepted on 02 Oct 2025

Siglec-9 acts as an immune checkpoint marker on MDSCs in Brucella Infection

in Adaptive immunity in infection

Huidong Shi
Xinxin Qi
Kaiyu Shang
Tingting Tian
Jianbing Ding
Mingzhe Li
Ruixue Xu
Fuling Pu
Junyu Kuang
Yuejie Zhu

Frontiers in Cellular and Infection Microbiology

doi 10.3389/fcimb.2025.1652116

193 views

Original Research

Published on 30 May 2025

Fusarium spp. and Aspergillus flavus infection induces pathogen-specific and pathogen-independent host immune response in patients with fungal keratitis

in Adaptive immunity in infection

Shreya Dinesh
Lalitha Prajna
Prajna Namperumalsamy Venkatesh
Kuppamuthu Dharmalingam
Bharanidharan Devarajan

Frontiers in Cellular and Infection Microbiology

doi 10.3389/fcimb.2025.1560628

3,048 views

Original Research

Published on 22 Apr 2025

Repeated-dose toxicity and immunogenicity evaluation of a recombinant subunit COVID-19 vaccine (ZF2001) in rats

in Adaptive immunity in infection

Ruimin Sun
Lijuan Xia
Guangbiao She
Jinrong Li
Yiru Wang
Yunxiang Chen
Qian Yang
Siming Zhang
Fang Liu
Ying Chen

Frontiers in Cellular and Infection Microbiology

doi 10.3389/fcimb.2025.1548787

2,399 views

Review

Published on 16 Apr 2025

The immune mechanisms of the urinary tract against infections

in Adaptive immunity in infection

Yilin Hou
Zhuoxuan Lv
Quanjie Hu
Aisong Zhu
Hongxia Niu

Frontiers in Cellular and Infection Microbiology

doi 10.3389/fcimb.2025.1540149

4,373 views
1 citation

Review

Published on 09 Dec 2024

Dysfunction and regulatory interplay of T and B cells in chronic hepatitis B: immunotherapy and emerging antiviral strategies

in Adaptive immunity in infection

Fei Yu
Yue Zhu
Shenghao Li
Liyuan Hao
Na Li
Fanghang Ye
Zhi Jiang
Xiaoyu Hu

Frontiers in Cellular and Infection Microbiology

doi 10.3389/fcimb.2024.1488527

4,208 views

Review

Published on 26 Feb 2024

Strategies of Helicobacter pylori in evading host innate and adaptive immunity: insights and prospects for therapeutic targeting

in Adaptive immunity in infection

Jiawei Fan
Jianshu Zhu
Hong Xu

Frontiers in Cellular and Infection Microbiology

doi 10.3389/fcimb.2024.1342913

11,707 views
21 citations

Review

Published on 23 Feb 2024

Marmosets as models of infectious diseases

in Adaptive immunity in infection

Ian C. T. Herron
Thomas R. Laws
Michelle Nelson

Frontiers in Cellular and Infection Microbiology

doi 10.3389/fcimb.2024.1340017

9,530 views
8 citations

Original Research

Published on 06 Dec 2023

Adaptive immune protection of the middle ears differs from that of the respiratory tract

in Adaptive immunity in infection

Kalyan K. Dewan
Amanda Caulfield
Yang Su
Colleen J. Sedney
Maiya Callender
Jillian Masters
Uriel Blas-Machado
Eric T. Harvill

Frontiers in Cellular and Infection Microbiology

doi 10.3389/fcimb.2023.1288057

3,329 views

Original Research

Published on 26 Oct 2023

Antigen specific activation of cytotoxic CD8+ T cells by Staphylococcus aureus infected dendritic cells

in Adaptive immunity in infection

Adèle Friot
Sophia Djebali
Séverine Valsesia
Peggy Parroche
Maxence Dubois
Jessica Baude
François Vandenesch
Jacqueline Marvel
Yann Leverrier

Frontiers in Cellular and Infection Microbiology

doi 10.3389/fcimb.2023.1245299

8,263 views
4 citations

Original Research

Published on 26 Oct 2023

Ex vivo and in vivo evidence that cigarette smoke-exposed T regulatory cells impair host immunity against Mycobacterium tuberculosis

in Adaptive immunity in infection

Xiyuan Bai
Deepshikha Verma
Cindy Garcia
Ariel Musheyev
Kevin Kim
Lorelenn Fornis
David E. Griffith
Li Li
Nicholas Whittel
Jacob Gadwa

Frontiers in Cellular and Infection Microbiology

doi 10.3389/fcimb.2023.1216492

4,636 views
3 citations

Original Research

Published on 03 Oct 2023

The effect of Toll-like receptor agonists on the immunogenicity of MVA-SARS-2-S vaccine after intranasal administration in mice

in Adaptive immunity in infection

Kim Thi Hoang Do
Stefanie Willenzon
Jasmin Ristenpart
Anika Janssen
Asisa Volz
Gerd Sutter
Reinhold Förster
Berislav Bošnjak

Frontiers in Cellular and Infection Microbiology

doi 10.3389/fcimb.2023.1259822

4,072 views
4 citations

Original Research

Published on 27 Jul 2023

Nipah virus attachment glycoprotein ectodomain delivered by type 5 adenovirus vector elicits broad immune response against NiV and HeV

in Adaptive immunity in infection

Xiaoyan Huang
Yaohui Li
Ruihua Li
Shaoyan Wang
Lu Yang
Shuyi Wang
Ying Yin
Xiaodong Zai
Jun Zhang
Junjie Xu

Frontiers in Cellular and Infection Microbiology

doi 10.3389/fcimb.2023.1180344

5,177 views
5 citations

Original Research

Published on 29 Jun 2023

Humoral immune responses to inactivated COVID-19 vaccine up to 1 year in children with chronic hepatitis B infection

in Adaptive immunity in infection

Yingzhi Zhou
Zhiwei Chen
Yi He
Xiaorong Peng
Yunan Chang
Aoxue Tan
Hu Li
Dachuan Cai
Peng Hu
Min Chen

Frontiers in Cellular and Infection Microbiology

doi 10.3389/fcimb.2023.1201101

3,324 views
1 citation

Original Research

Published on 23 Jun 2023

Differential cellular and humoral immune responses in immunocompromised individuals following multiple SARS-CoV-2 vaccinations

in Adaptive immunity in infection

Rhys T. Meredith
Max D. Bermingham
Kirsten Bentley
Sayeh Agah
Abigail Aboagye-Odei
Ross A. R. Yarham
Hayley Mills
Muddassir Shaikh
Neil Hoye
Richard J. Stanton

Frontiers in Cellular and Infection Microbiology

doi 10.3389/fcimb.2023.1207313

5,006 views
6 citations

Original Research

Published on 10 May 2023

Clinical characteristics and outcomes of children with Kawasaki disease combined with sepsis in the pediatric intensive care unit

in Adaptive immunity in infection

Yufan Yang
Jiaotian Huang
Haipeng Yan
Xun Li
Pingping Liu
Wu Zhou
Xinping Zhang
Xiulan Lu
Zhenghui Xiao

Frontiers in Cellular and Infection Microbiology

doi 10.3389/fcimb.2023.1101428

2,700 views