Frontiers in Cellular and Infection Microbiology | Clinical and Diagnostic Microbiology and Immunology

Original Research

Accepted on 23 Oct 2025

Clinical Application of Metagenomic Next-Generation Sequencing in the diagnosis of severe pneumonia pathogens

in Clinical and Diagnostic Microbiology and Immunology

Ying Zhang
Caitao Dong
Raojuan Huang
Jingdi Chen
Handong Zou
Yang Liu
Mengmeng GUO
Hang Gao
Quan Ke
Wei Wu

Frontiers in Cellular and Infection Microbiology

doi 10.3389/fcimb.2025.1661213

Original Research

Accepted on 23 Oct 2025

Impact of Metagenomic sequencing on Clinical Outcomes in Patients with Suspected Central Nervous System Infections: A Retrospective Case-Control Study

in Clinical and Diagnostic Microbiology and Immunology

Wenyan An
Yandong Zhang
Yong Liu
Tianshi Yang
Shiqi Bai
Peiwen Zhou
Junzhuo Si
Yuan Zhao
Yulu He
Yijia Pan

Frontiers in Cellular and Infection Microbiology

doi 10.3389/fcimb.2025.1677092

Review

Accepted on 23 Oct 2025

Application of Matrix-Assisted Laser Desorption/Ionization Time-of-Flight Mass Spectrometry in Clinical Testing and Diagnosis

in Clinical and Diagnostic Microbiology and Immunology

Qiushuang Xiong
Haotong Guan

Frontiers in Cellular and Infection Microbiology

doi 10.3389/fcimb.2025.1607258

Review

Published on 23 Oct 2025

From 1D microbiological assays to 3D advanced skin models: enhancing preclinical strategies to unravel the impact of bioactive textiles on the human skin microbiome

in Clinical and Diagnostic Microbiology and Immunology

Irina Negut
Camilla Mazzanti
Rossella Laurano
Gianluca Ciardelli
Simona Bronco
Cláudia S. Oliveira

Frontiers in Cellular and Infection Microbiology

doi 10.3389/fcimb.2025.1676663

250 views

Original Research

Accepted on 22 Oct 2025

Comparison and evaluation of metagenomic next-generation sequencing (mNGS) and real-time PCR for the detection of Mycobacterium tuberculosis diagnosis

in Clinical and Diagnostic Microbiology and Immunology

Yanhong Wang
Penghao Guo
Yaoming Chen
Hongji Zhu
Xuegao Yu
Jiankai Deng

Frontiers in Cellular and Infection Microbiology

doi 10.3389/fcimb.2025.1694179

106 views

Original Research

Published on 22 Oct 2025

Utilization of targeted sequencing for etiological diagnosis of pulmonary infections in different samples

in Clinical and Diagnostic Microbiology and Immunology

Xiaojun Guan
Kaisar Gufur
Liangliang Xu
Cuncun Chen
Ning Yu
Yi Fu
Mingjie Zhou
Abla Nurmamat

Frontiers in Cellular and Infection Microbiology

doi 10.3389/fcimb.2025.1683489

477 views

Original Research

Published on 21 Oct 2025

Bacterial DNA detection in blood using PCR/ESI-MS in neonates with suspected early onset infection

in Clinical and Diagnostic Microbiology and Immunology

Ajay K. Sinha
Anja Saso
Arikana Mufunde
Steven T. Kempley
Mark Wilks
Mike Millar

Frontiers in Cellular and Infection Microbiology

doi 10.3389/fcimb.2025.1579624

531 views

Original Research

Accepted on 20 Oct 2025

Recirculating glass pipettes constitute a high risk when working with freshly isolated immune cells - the presence of bacterial pyrogenic material

in Clinical and Diagnostic Microbiology and Immunology

Srinivas Akula
Sandra Lara
Anna-Karin Olsson
Lars Torkel Hellman

Frontiers in Cellular and Infection Microbiology

doi 10.3389/fcimb.2025.1689489

Original Research

Published on 20 Oct 2025

Early bacterial communities in the lower airways and intestines of caesarean section neonates with respiratory disease

in Clinical and Diagnostic Microbiology and Immunology

Yonghua Wei
Yang Wang
Shiyi Sun
Zhimin Zhao
Weiqun Lu
Yan Ma
Jie Chen
Li Xu
Kerong Li

Frontiers in Cellular and Infection Microbiology

doi 10.3389/fcimb.2025.1562791

726 views

Original Research

Published on 15 Oct 2025

Infected necrotizing pancreatitis: clinical features, microbial patterns, and outcomes in a Saudi tertiary center

in Clinical and Diagnostic Microbiology and Immunology

Moaz Abulfaraj

Frontiers in Cellular and Infection Microbiology

doi 10.3389/fcimb.2025.1689728

570 views

Original Research

Accepted on 14 Oct 2025

An interpretable machine learning model for Early Prediction of Escherichia coli Infection in ICU Patients

in Clinical and Diagnostic Microbiology and Immunology

Shu Yang
Laiyu Zou
Huixin Liang
Xiaohong Xu
Xiaoling Chen

Frontiers in Cellular and Infection Microbiology

doi 10.3389/fcimb.2025.1682764

318 views

Original Research

Published on 10 Oct 2025

Impact of discontinuing automatic reflex urine culture after urinalysis: a diagnostic and antibiotic stewardship initiative

in Clinical and Diagnostic Microbiology and Immunology

Blaine Berger
Janell Lukey
Chetan Jinadatha
Dhammika H. Navarathna

Frontiers in Cellular and Infection Microbiology

doi 10.3389/fcimb.2025.1572936

914 views

Original Research

Published on 08 Oct 2025

Comparative study of antibiotic adsorption capacity of three brands of blood culture bottles

in Clinical and Diagnostic Microbiology and Immunology

Siqi Yuan
Jinxue Yang
Nan Deng
Jiayi Peng
Ling Ma
Shuaixian Du

Frontiers in Cellular and Infection Microbiology

doi 10.3389/fcimb.2025.1571264

1,002 views

Original Research

Accepted on 07 Oct 2025

Reality Check: Testing the in silico Predictions of False Negative Results Due to Mutations in SARS-CoV-2 PCR assays Using Templates with Mismatches in vitro

in Clinical and Diagnostic Microbiology and Immunology

Taylor Otwell
Brittany Knight
Michael Coryell
Jennifer Stone
Phillip Davis
Bryan Necciai
Paul Edward Carlson
Yan Yi
Shanmuga Sozhamannan

Frontiers in Cellular and Infection Microbiology

doi 10.3389/fcimb.2025.1524025

280 views

Original Research

Accepted on 06 Oct 2025

Multi-Omics Approaches for Image Classification in Disease Diagnosis

in Clinical and Diagnostic Microbiology and Immunology

Jinshan Che
Mingming Sun
Yuhong Wang

Frontiers in Cellular and Infection Microbiology

doi 10.3389/fcimb.2025.1616189

130 views

Original Research

Published on 06 Oct 2025

Absolute quantification of VBNC state formation and resuscitation in alcohol-producing Klebsiella pneumoniae

in Clinical and Diagnostic Microbiology and Immunology

Shuo Zhao
Chenpu Dou
Yang Yang
Jiazheng Wang
Meng Li
Bin Yang
Jing Yuan
Jian Zhang

Frontiers in Cellular and Infection Microbiology

doi 10.3389/fcimb.2025.1627943

884 views