Frontiers in Cellular Neuroscience | Cellular Neuropathology

Review

Published on 22 Jul 2025

Ferroptosis in central nervous system injuries: molecular mechanisms, diagnostic approaches, and therapeutic strategies

in Cellular Neuropathology

Qiuhu Huang
Haowen Zhang
Shenbo Chen
Yao Wang
Jian Zhou

Frontiers in Cellular Neuroscience

doi 10.3389/fncel.2025.1593963

2,946 views
6 citations

Original Research

Published on 22 Jul 2025

β-catenin-α-catenin and actomyosin signaling differentially regulate growth cone contours and axon undulation and branching of retinal ganglion cells in situ

in Cellular Neuropathology

Valerie Lew
Sukaynah Khetani
Simran Kaur
William Woodward
Sukmin Sandhu
Radhika Rawat
Tamira Elul

Frontiers in Cellular Neuroscience

doi 10.3389/fncel.2025.1572298

1,701 views
1 citation

Original Research

Published on 22 Jul 2025

NF-κB RelA regulates temporal oligodendrocyte differentiation in the postnatal brains

in Cellular Neuropathology

Kamonrapat Sompub
Norihisa Bizen
Albert S. Baldwin
Hirohide Takebayashi

Frontiers in Cellular Neuroscience

doi 10.3389/fncel.2025.1622874

2,820 views

Editorial

Published on 15 Jul 2025

Editorial: Recent advances in mitochondrial dysfunction and therapeutics for neurodegeneration and aging

in Cellular Neuropathology

Monokesh K. Sen
Keagan Dunville
Nicole Miles
Michelle Newbery
Neville S. Ng
Lezanne Ooi

Frontiers in Cellular Neuroscience

doi 10.3389/fncel.2025.1650938

2,835 views

Review

Published on 04 Jul 2025

Broccoli for the brain: a review of the neuroprotective mechanisms of sulforaphane

in Cellular Neuropathology

Riley N. Bessetti
Karen A. Litwa

Frontiers in Cellular Neuroscience

doi 10.3389/fncel.2025.1601366

9,060 views
7 citations

Original Research

Published on 01 Jul 2025

Tear deficiency transforms spatial distribution of corneal calcitonin gene-related peptide-positive nerves in rats

in Cellular Neuropathology

Takeshi Kiyoi
Akihiro Nakajima
Qiang He
Li Liu
Shijie Zheng
Shizuka Kobayashi
Junsuke Uwada
Takayoshi Masuoka

Frontiers in Cellular Neuroscience

doi 10.3389/fncel.2025.1619310

2,733 views

Mini Review

Published on 27 Jun 2025

Sialylation as a checkpoint for inflammatory and complement-related retinal diseases

in Cellular Neuropathology

Yiduo Min
German Cuevas-Rios
Thomas Langmann
Harald Neumann

Frontiers in Cellular Neuroscience

doi 10.3389/fncel.2025.1623755

3,786 views
1 citation

Original Research

Published on 27 Jun 2025

Circulating exosomes with unique lipid signature in relapsing remitting multiple sclerosis

in Cellular Neuropathology

Claudia Palazzo
Ilaria Asci
Silvia Russo
Cinzia Buccoliero
Vincenzo Mangialardi
Pasqua Abbrescia
Onofrio Valente
Maddalena Ruggieri
Damiano Paolicelli
Simona Lobasso

Frontiers in Cellular Neuroscience

doi 10.3389/fncel.2025.1613618

2,789 views
3 citations

Original Research

Published on 26 Jun 2025

PTEN in somatostatin neurons regulates fear and anxiety and is required for inhibitory synaptic connectivity within central amygdala

in Cellular Neuropathology

Timothy W. Holford
Kaitlyn N. Letourneau
Carolyn Von-Walter
Daniela Moncaleano
Cody L. Loomis
M. McLean Bolton

Frontiers in Cellular Neuroscience

doi 10.3389/fncel.2025.1597131

5,269 views
2 citations

Systematic Review

Published on 25 Jun 2025

Is environmental enrichment effective in modulating autophagy markers in the brain exposed to adverse conditions? A systematic review

in Cellular Neuropathology

Clarice Beatriz Gonçalves Silva
Matheus Santos de Sousa Fernandes
Debora Dantas Nucci Cerqueira
Gabriela Carvalho Jurema Santos
Fatma Hilal Yagin
Yalin Aygun
Georgian Badicu
Fabiana S. Evangelista
Pablo Prieto-González
Fabrício Oliveira Souto

Frontiers in Cellular Neuroscience

doi 10.3389/fncel.2025.1624500

2,383 views

Review

Published on 24 Jun 2025

The role of oxidative stress in spinal cord ischemia reperfusion injury: mechanisms and therapeutic implications

in Cellular Neuropathology

Yu Xing
Yuan-zhang Xiao
Min Zhao
Jiang-jun Zhou
Kai Zhao
Chun-lin Xiao

Frontiers in Cellular Neuroscience

doi 10.3389/fncel.2025.1590493

3,608 views
2 citations

Correction

Published on 23 Jun 2025

Corrigendum: O6-methylguanine DNA methyltransferase (MGMT) expression in U1242 glioblastoma cells enhances in vitro clonogenicity, tumor implantation in vivo, and sensitivity to alisertib-carboplatin combination treatment

in Cellular Neuropathology

Müge Sak
Brian J. Williams
Andrew J. Hey
Mayur Sharma
Leslie Schier
Megan J. Wilson
Mahatma Ortega
Alyssa I. Lara
Mikaela N. Brentlinger
Norman L. Lehman

Frontiers in Cellular Neuroscience

doi 10.3389/fncel.2025.1637837

1,216 views

Original Research

Published on 20 Jun 2025

Knockdown and overexpression of basolateral amygdala SIRT1 via AAV bidirectionally alter morphine-induced conditioned place preference extinction in mice

in Cellular Neuropathology

Guo Hao
Yao Mingchen
Zheng Yalin
Qu Yaqi
Yang Tingwu
Xing Xinru
Li Kaixuan
Dong Yani
Liu Dongsen

Frontiers in Cellular Neuroscience

doi 10.3389/fncel.2025.1604914

1,864 views

Original Research

Published on 18 Jun 2025

Evaluation of retinal structure changes with AI-based OCT image segmentation for sodium iodate induced retinal degeneration

in Cellular Neuropathology

Yong Zeng
Jiaming Zhou
Yichao Li
Bruno Alvisio
Jacob Czech
David Bissig
Haohua Qian

Frontiers in Cellular Neuroscience

doi 10.3389/fncel.2025.1605639

3,209 views
2 citations

Review

Published on 18 Jun 2025

Research progress on the mechanisms of endogenous neural stem cell differentiation in spinal cord injury repair

in Cellular Neuropathology

Tianwei Wang
Qing Han
Shi Lv
Li-ping Zhang
Hengrui Li
Jian Liu
Jinyi Kuang
Bao-liang Sun
Jing-yi Sun

Frontiers in Cellular Neuroscience

doi 10.3389/fncel.2025.1592297

4,238 views
3 citations

Mini Review

Published on 13 Jun 2025

Bridging the brain and gut: neuroimmune mechanisms of neuroinflammation and therapeutic insights

in Cellular Neuropathology

Ludmila Müller
Svetlana Di Benedetto

Frontiers in Cellular Neuroscience

doi 10.3389/fncel.2025.1590002

6,139 views
9 citations

Original Research

Published on 06 Jun 2025

Integrative bioinformatics and machine learning identify iron metabolism genes MAP4, GPT, and HIRIP3 as diagnostic biomarkers and therapeutic targets in Alzheimer’s disease

in Cellular Neuropathology

Xiaoqiong An
Xiangguang Zeng
Zhenzhen Yi
Manni Cao
Yijia Wang
Wenfeng Yu
Zhenkui Ren

Frontiers in Cellular Neuroscience

doi 10.3389/fncel.2025.1610682

2,849 views
1 citation

Original Research

Published on 04 Jun 2025

Influence of chronic alcohol consumption on cerebral ischemia/reperfusion injury in female mice

in Cellular Neuropathology

Utsab Subedi
Pushpa Subedi
Asia Rogers
Xiao-Hong Lu
Manikandan Panchatcharam
Hong Sun

Frontiers in Cellular Neuroscience

doi 10.3389/fncel.2025.1600725

2,700 views
1 citation

Original Research

Published on 04 Jun 2025

Identification of actin mutants with neurodegenerative disease-like phenotypes via mutagenesis of the actin-ATP interface

in Cellular Neuropathology

Noah Mann
Keerthana Surabhi
Josephine Sharp
Mary Phipps
Maelee Becton
Jahiem Hill
Davis Roberts
Erzsebet M. Szatmari
Robert M. Hughes

Frontiers in Cellular Neuroscience

doi 10.3389/fncel.2025.1543199

2,027 views

Review

Published on 20 May 2025

Role of mitochondrial quality control in neurodegenerative disease progression

in Cellular Neuropathology

Tingting Liu
Weibo Sun
Shuhao Guo
Zhiying Yuan
Minghang Zhu
Jing Lu
Tao Chen
Yuanyuan Qu
Chuwen Feng
Tiansong Yang

Frontiers in Cellular Neuroscience

doi 10.3389/fncel.2025.1588645

5,439 views
7 citations

Review

Published on 09 May 2025

Mitochondria: the hidden engines of traumatic brain injury-driven neurodegeneration

in Cellular Neuropathology

Olusola A. Olatona
Sydney P. Sterben
Sahan B. S. Kansakar
Aviva J. Symes
Volha Liaudanskaya

Frontiers in Cellular Neuroscience

doi 10.3389/fncel.2025.1570596

6,947 views
10 citations

Editorial

Published on 08 May 2025

Editorial: Physiological and pathological changes of the retina associated with ageing

in Cellular Neuropathology

Ana I. Arroba
Eleni Beli
Jose R. Hombrebueno
María Llorián-Salvador

Frontiers in Cellular Neuroscience

doi 10.3389/fncel.2025.1609473

2,256 views

Mini Review

Published on 07 May 2025

The potential of repurposing clemastine to promote remyelination

in Cellular Neuropathology

Reiji Yamazaki
Nobuhiko Ohno

Frontiers in Cellular Neuroscience

doi 10.3389/fncel.2025.1582902

6,417 views
4 citations

Review

Published on 28 Apr 2025

Targeting autophagy in astrocytes: a potential for neurodegenerative disease intervention

in Cellular Neuropathology

Maja Potokar
Jernej Jorgačevski

Frontiers in Cellular Neuroscience

doi 10.3389/fncel.2025.1584767

4,695 views
4 citations

2,080 articles

articles

Ferroptosis in central nervous system injuries: molecular mechanisms, diagnostic approaches, and therapeutic strategies

β-catenin-α-catenin and actomyosin signaling differentially regulate growth cone contours and axon undulation and branching of retinal ganglion cells in situ

NF-κB RelA regulates temporal oligodendrocyte differentiation in the postnatal brains

Editorial: Recent advances in mitochondrial dysfunction and therapeutics for neurodegeneration and aging

Broccoli for the brain: a review of the neuroprotective mechanisms of sulforaphane

Tear deficiency transforms spatial distribution of corneal calcitonin gene-related peptide-positive nerves in rats

Sialylation as a checkpoint for inflammatory and complement-related retinal diseases

Circulating exosomes with unique lipid signature in relapsing remitting multiple sclerosis

PTEN in somatostatin neurons regulates fear and anxiety and is required for inhibitory synaptic connectivity within central amygdala

Is environmental enrichment effective in modulating autophagy markers in the brain exposed to adverse conditions? A systematic review

The role of oxidative stress in spinal cord ischemia reperfusion injury: mechanisms and therapeutic implications

Corrigendum: O6-methylguanine DNA methyltransferase (MGMT) expression in U1242 glioblastoma cells enhances in vitro clonogenicity, tumor implantation in vivo, and sensitivity to alisertib-carboplatin combination treatment

Knockdown and overexpression of basolateral amygdala SIRT1 via AAV bidirectionally alter morphine-induced conditioned place preference extinction in mice

Evaluation of retinal structure changes with AI-based OCT image segmentation for sodium iodate induced retinal degeneration

Research progress on the mechanisms of endogenous neural stem cell differentiation in spinal cord injury repair

Bridging the brain and gut: neuroimmune mechanisms of neuroinflammation and therapeutic insights

Integrative bioinformatics and machine learning identify iron metabolism genes MAP4, GPT, and HIRIP3 as diagnostic biomarkers and therapeutic targets in Alzheimer’s disease

Influence of chronic alcohol consumption on cerebral ischemia/reperfusion injury in female mice

Identification of actin mutants with neurodegenerative disease-like phenotypes via mutagenesis of the actin-ATP interface

Role of mitochondrial quality control in neurodegenerative disease progression

Mitochondria: the hidden engines of traumatic brain injury-driven neurodegeneration

Editorial: Physiological and pathological changes of the retina associated with ageing

The potential of repurposing clemastine to promote remyelination

Targeting autophagy in astrocytes: a potential for neurodegenerative disease intervention