Frontiers in Dental Medicine | Oral-Systemic Immunology

Editorial

Published on 29 Jul 2026

Editorial: A holistic approach to oral–systemic health care: integrating natural and modern therapies

in Oral-Systemic Immunology

Mario Taba
Ammaar H. Abidi
Kavita Chandrasekaran

Frontiers in Dental Medicine

doi 10.3389/fdmed.2026.1908324

1,876 views

Review

Published on 17 Jul 2026

Periodontal disease and endocrine imbalance: a molecular pathways perspective

in Oral-Systemic Immunology

Mireya Martínez-García
Enrique Hernández-Lemus

Frontiers in Dental Medicine

doi 10.3389/fdmed.2026.1886028

3,538 views
1 citation

Case Report

Published on 15 Jul 2026

Case Report: Longitudinal temporomandibular joint remodeling in MMP2 associated nodulosis arthropathy osteolysis syndrome during serial panoramic follow up

in Oral-Systemic Immunology

Abdullah Alzahem
Abdullah Alghamdi
Wael Aboelmaaty

Frontiers in Dental Medicine

doi 10.3389/fdmed.2026.1876677

1,556 views

Original Research

Published on 19 Jun 2026

Salivary biomarker profiling in prediabetes-associated periodontitis: role of adiponectin, resistin, and total matrix metalloproteinase-8

in Oral-Systemic Immunology

Julie Toby Thomas
Betsy Joseph
Sajit Varghese
Nebu George Thomas
Kavya S
Toby Thomas
Timo Sorsa
Sukumaran Anil
Tuomas Waltimo

Frontiers in Dental Medicine

doi 10.3389/fdmed.2026.1873996

3,870 views

Mini Review

Published on 03 Jun 2026

Mineral encapsulation of microorganisms in calcified oral biofilms: implications for immune dysregulation and vascular calcification

in Oral-Systemic Immunology

Jayalaxmi Shetty
Nishmitha N. Hegde
Mithra N. Hegde

Frontiers in Dental Medicine

doi 10.3389/fdmed.2026.1849108

4,770 views

Review

Published on 22 Apr 2026

Oral microbiota and urinary system diseases: from mechanistic insights to clinical implications—a comprehensive review

in Oral-Systemic Immunology

Haoling Chen
Yanan Chen
Yiwen Liu
Chuxiao Chen

Frontiers in Dental Medicine

doi 10.3389/fdmed.2026.1803961

4,545 views

Systematic Review

Published on 31 Mar 2026

Immune suppression, HLA-risk and potential future immune based targets of oral leukoplakia progression

in Oral-Systemic Immunology

Mehar Soni
Bryce DeSantis
Alessandro Villa
Malek Kamoun
James Gates

Frontiers in Dental Medicine

doi 10.3389/fdmed.2026.1665195

4,350 views

Systematic Review

Published on 29 Sep 2025

Salivary biomarkers for the prognosis of oncological and infectious diseases: a systematic review

in Oral-Systemic Immunology

Heber Isac Arbildo-Vega
Saurav Panda
Fredy Hugo Cruzado-Oliva
Hernán Vásquez-Rodrigo
Rubén Aguirre-Ipenza
Joan Manuel Meza-Málaga
Sara Antonieta Luján-Valencia
Eduardo Luján-Urviola
Carlos Alberto Farje-Gallardo
Tania Belú Castillo-Cornock

Frontiers in Dental Medicine

doi 10.3389/fdmed.2025.1662276

4,094 views
6 citations

Original Research

Published on 29 Jul 2025

Unveiling the association between angiogenic imbalance in the gingival crevicular fluid in maternal periodontitis and spontaneous preterm birth

in Oral-Systemic Immunology

Daniela Albers
María José Bendek
Marcela Hernández
Diego Prieto
Carolina Rojas
María Luisa Mizgier
Patricia Hernández
Sebastián E. Illanes
Alejandra Chaparro

Frontiers in Dental Medicine

doi 10.3389/fdmed.2025.1625995

3,551 views
2 citations

Original Research

Published on 08 Jul 2025

Salivary gland transcriptomic analysis and immunophenotyping in the IL-14α transgenic mouse model of Sjögren's disease

in Oral-Systemic Immunology

Lucas T. Woods
Kimberly J. Jasmer
Kevin Muñoz Forti
Alex Kearns
Gary A. Weisman

Frontiers in Dental Medicine

doi 10.3389/fdmed.2025.1612522

5,827 views
1 citation

Original Research

Published on 12 Jun 2025

Multiparameter flow cytometry enables immune profiling and IFN pathway analysis in human minor salivary glands

in Oral-Systemic Immunology

Eiko Yamada
Kalie Dominick
Rachel J. Kulchar
Joseph Twohig
Zohreh Khavandgar
Margaret Beach
Eileen Pelayo
Alan Baer
Paola Perez
Blake M. Warner

Frontiers in Dental Medicine

doi 10.3389/fdmed.2025.1590516

4,124 views
2 citations

Brief Research Report

Published on 09 May 2025

Influence of nitrate-containing arugula juice on nitrate-reducing oral bacteria and periodontopathogens in smokers’ biofilm

in Oral-Systemic Immunology

Boy M. Bachtiar
Irene E. Rieuwpassa
Heni Susilowati
Retno Indrawati
Citra F. Theodorea
Turmidzi Fath
Endang W. Bachtiar

Frontiers in Dental Medicine

doi 10.3389/fdmed.2025.1545479

4,360 views

Systematic Review

Published on 10 Feb 2025

Apical periodontitis in inflammatory bowel disease: a meta-analysis at patient and tooth level

in Oral-Systemic Immunology

Giusy Rita Maria La Rosa
Alejandro Ismael Lorenzo-Pouso
Vito Carlo Alberto Caponio
Mariangela Valentina Puci

Frontiers in Dental Medicine

doi 10.3389/fdmed.2025.1553914

6,374 views
14 citations

Mini Review

Published on 06 Jan 2025

Nanosystems for modulation of immune responses in periodontal therapy: a mini-review

in Oral-Systemic Immunology

Anirudh B. Acharya
Usha Hegde
Swetha Acharya

Frontiers in Dental Medicine

doi 10.3389/fdmed.2024.1509775

4,367 views
5 citations

Original Research

Published on 18 Dec 2024

Screening for diabetes and hypertension in adult dental patients: the experience in a Nigerian dental center

in Oral-Systemic Immunology

Ukachi Chiwendu Nnawuihe
Emmauel Adetolu Adelusi
Afolake Shakirat Salami
Ezekiel Taiwo Adebayo
Lilian Ejije Ahaji

Frontiers in Dental Medicine

doi 10.3389/fdmed.2024.1468375

2,768 views

Original Research

Published on 19 Nov 2024

Stannous fluoride protects gingival keratinocytes against infection and oxidative stress by Porphyromonas gingivalis outer membrane vesicles

in Oral-Systemic Immunology

Sancai Xie
Cheryl S. Tansky
Julie Ashe
Fei Gao
Nivedita B. Ramji
Vighter Iberi
Yiping Sun
Niranjan Ramji
Aaron R. Biesbrock

Frontiers in Dental Medicine

doi 10.3389/fdmed.2024.1492369

5,534 views
9 citations

Hypothesis and Theory

Published on 21 Aug 2024

Integration of precision medicine into the dental care setting

in Oral-Systemic Immunology

Larissa Steigmann
Željka Perić Kačarević
Jessica Khoury
Katalin Nagy
Magda Feres

Frontiers in Dental Medicine

doi 10.3389/fdmed.2024.1398897

7,314 views
13 citations

Editorial

Published on 12 Jun 2024

Editorial: Salivary biomarkers for oral and systemic diseases

in Oral-Systemic Immunology

Mario Taba
Melissa M. Grant

Frontiers in Dental Medicine

doi 10.3389/fdmed.2024.1429305

3,568 views
2 citations

Original Research

Published on 04 Apr 2024

Serum MMP-8 and TIMP-1 concentrations in a population-based cohort: effects of age, gender, and health status

in Oral-Systemic Immunology

Julia Ranta
Aki S. Havulinna
Taina Tervahartiala
Katriina Niemi
Ghazal Aarabi
Terhi Vihervaara
Veikko Salomaa
Timo Sorsa
Pirkko J. Pussinen
Aino Salminen

Frontiers in Dental Medicine

doi 10.3389/fdmed.2024.1315596

6,040 views
9 citations

Editorial

Published on 25 Mar 2024

Editorial: Cross-kingdom interactions in oral dysbiosis and host response

in Oral-Systemic Immunology

Zvi G. Loewy

Frontiers in Dental Medicine

doi 10.3389/fdmed.2024.1398868

2,277 views

Original Research

Published on 18 Mar 2024

Variability of salivary analytes under daily conditions and their implications for periodontitis biomarkers

in Oral-Systemic Immunology

Amanda Carolina Souza Delfino Rocha
Renata Klemp Orlandini
Ana Carolina Fragoso Motta
Juliana Barchelli Pinheiro
Gilberto André e Silva
Viviane de Cássia Oliveira
Alan Grupioni Lourenço

Frontiers in Dental Medicine

doi 10.3389/fdmed.2024.1369186

4,378 views
9 citations

Review

Published on 16 May 2023

Sex-specific differences in primary Sjögren's disease

in Oral-Systemic Immunology

Achamaporn Punnanitinont
Jill M. Kramer

Frontiers in Dental Medicine

doi 10.3389/fdmed.2023.1168645

8,382 views
12 citations

Original Research

Published on 14 Mar 2023

Digital imaging and qPCR analysis and comparison of short-term plaque removal effects of toothbrushing

in Oral-Systemic Immunology

Yuanyuan Luo
Danni Wang
Yuxiao Li
Dezhi Geng
Bei Yu
Yueping Zhao
Qi Xiang

Frontiers in Dental Medicine

doi 10.3389/fdmed.2023.1103602

4,202 views
1 citation

Review

Published on 13 Mar 2023

ErbB- and MUC1-targeted CAR-T cell immunotherapy of oral squamous cell carcinoma

in Oral-Systemic Immunology

Saffron E. Summers
Vehid Salih
Andrew D. Foey

Frontiers in Dental Medicine

doi 10.3389/fdmed.2023.1116402

9,500 views
8 citations

25 articles

articles

Editorial: A holistic approach to oral–systemic health care: integrating natural and modern therapies

Periodontal disease and endocrine imbalance: a molecular pathways perspective

Case Report: Longitudinal temporomandibular joint remodeling in MMP2 associated nodulosis arthropathy osteolysis syndrome during serial panoramic follow up

Salivary biomarker profiling in prediabetes-associated periodontitis: role of adiponectin, resistin, and total matrix metalloproteinase-8

Mineral encapsulation of microorganisms in calcified oral biofilms: implications for immune dysregulation and vascular calcification

Oral microbiota and urinary system diseases: from mechanistic insights to clinical implications—a comprehensive review

Immune suppression, HLA-risk and potential future immune based targets of oral leukoplakia progression

Salivary biomarkers for the prognosis of oncological and infectious diseases: a systematic review

Unveiling the association between angiogenic imbalance in the gingival crevicular fluid in maternal periodontitis and spontaneous preterm birth

Salivary gland transcriptomic analysis and immunophenotyping in the IL-14α transgenic mouse model of Sjögren's disease

Multiparameter flow cytometry enables immune profiling and IFN pathway analysis in human minor salivary glands

Influence of nitrate-containing arugula juice on nitrate-reducing oral bacteria and periodontopathogens in smokers’ biofilm

Apical periodontitis in inflammatory bowel disease: a meta-analysis at patient and tooth level

Nanosystems for modulation of immune responses in periodontal therapy: a mini-review

Screening for diabetes and hypertension in adult dental patients: the experience in a Nigerian dental center

Stannous fluoride protects gingival keratinocytes against infection and oxidative stress by Porphyromonas gingivalis outer membrane vesicles

Integration of precision medicine into the dental care setting

Editorial: Salivary biomarkers for oral and systemic diseases

Serum MMP-8 and TIMP-1 concentrations in a population-based cohort: effects of age, gender, and health status

Editorial: Cross-kingdom interactions in oral dysbiosis and host response

Variability of salivary analytes under daily conditions and their implications for periodontitis biomarkers

Sex-specific differences in primary Sjögren's disease

Digital imaging and qPCR analysis and comparison of short-term plaque removal effects of toothbrushing

ErbB- and MUC1-targeted CAR-T cell immunotherapy of oral squamous cell carcinoma