Frontiers in Endocrinology | Diabetes: Molecular Mechanisms

Original Research

Published on 12 Feb 2026

Effects and interactive effects of high-altitude environment on metabolism in normal and diabetic populations: a comparative metabolomics study

in Diabetes: Molecular Mechanisms

Jing Shi
Jinli Meng
Chenghui Zhang
Li Feng
Suyuan Wang
Hengyan Li
Yongyue Guo
Xin Hu
Xiaomei Li
Wanlin He

Frontiers in Endocrinology

doi 10.3389/fendo.2026.1736270

113 views

Systematic Review

Published on 12 Feb 2026

Lipoprotein-associated phospholipase A2 and complications of diabetes mellitus: a systematic review and meta-analysis

in Diabetes: Molecular Mechanisms

Sujuan Guo
Xiaojuan Zhao

Frontiers in Endocrinology

doi 10.3389/fendo.2026.1765261

174 views

Original Research

Published on 12 Feb 2026

TangShenWeiNing formula alleviates diabetic kidney disease by inhibiting ferroptosis via AMPK pathway in renal tubular epithelial cells

in Diabetes: Molecular Mechanisms

Ye Jiang
Jing Chang
You Guo
Zhe Liu
Xiaomeng Feng

Frontiers in Endocrinology

doi 10.3389/fendo.2026.1749994

125 views

Review

Published on 12 Feb 2026

Mechanisms and applications of natural plant ingredients in modulating amino acid metabolism for the improvement of diabetic retinopathy: a review

in Diabetes: Molecular Mechanisms

Le-yi Zhang
Tian-yi Zhang
Ya-juan Zheng
Jia-xin Li
Hu-rong Chen
Jing Cao
Teng Dan

Frontiers in Endocrinology

doi 10.3389/fendo.2026.1745507

180 views

Original Research

Accepted on 11 Feb 2026

Inflammatory markers associated with albuminuria and early atherosclerosis in type 2 diabetic kidney disease: a cross-sectional study

in Diabetes: Molecular Mechanisms

Ainhoa González-Luis
Carolina Hernández-Carballo
Carmen Mora-Fernández
Ernesto Martín-Núñez
J. Diego Carlos-Monzón
Juan F. Navarro-González
Javier Donate-Correa

Frontiers in Endocrinology

Review

Published on 11 Feb 2026

The SGLT2 inhibitor checklist: a comprehensive review of perioperative and acute phase safety management

in Diabetes: Molecular Mechanisms

Bin Deng
Wenhua Liu
Qingmin Chu

Frontiers in Endocrinology

doi 10.3389/fendo.2026.1777334

535 views

Systematic Review

Published on 09 Feb 2026

Clinical parameters and emerging biomarkers of partial remission in pediatric type 1 diabetes: a systematic review

in Diabetes: Molecular Mechanisms

Camille Dikranian
Oumayma Hadara
Philippe A. Lysy

Frontiers in Endocrinology

doi 10.3389/fendo.2026.1758848

433 views

Original Research

Published on 03 Feb 2026

Aerobic exercise and MOTS-c attenuate diabetic myocardial fibrosis via inhibition of the THBS1/TGF-β signaling pathway

in Diabetes: Molecular Mechanisms

Zhiyu Li
Tutu Wang
Yu Fu
Feilong Chen
Shunchang Li

Frontiers in Endocrinology

doi 10.3389/fendo.2026.1732329

357 views

Review

Published on 03 Feb 2026

Ferroptosis in diabetic retinopathy: from pathogenic mechanisms to translational prospects

in Diabetes: Molecular Mechanisms

Jieyu Jiang
Zhimin Liu
Xiangdong Chen

Frontiers in Endocrinology

doi 10.3389/fendo.2026.1765089

854 views

Review

Accepted on 30 Jan 2026

The Role of PYY in Improving Insulin Resistance

in Diabetes: Molecular Mechanisms

Chunyan Liu
Na Ren
Haixin Zhang
Jian Ma

Frontiers in Endocrinology

489 views

Review

Accepted on 29 Jan 2026

Endoplasmic Reticulum Stress in Skeletal Muscle Dysfunction of Type 2 Diabetes: Mechanisms and Therapeutic Implications

in Diabetes: Molecular Mechanisms

Xin Wang
Mingdi Li
Zengpeng Chi
Mingshan Wang
Jiayi Liu
Ailin Li
Bailin Song
Le Tong

Frontiers in Endocrinology

193 views

Original Research

Published on 29 Jan 2026

Identification of maturity-onset diabetes of the young through targeted next-generation sequencing in Thai patients with atypical diabetes in real-world practice

in Diabetes: Molecular Mechanisms

Yotsapon Thewjitcharoen
Waralee Chatchomchuan
Ekgaluck Wanothayaroj
Soontaree Nakasatien
Cadmon K. P. Lim
Thep Himathongkam
Juliana C. N. Chan

Frontiers in Endocrinology

doi 10.3389/fendo.2026.1717121

445 views

Review

Accepted on 28 Jan 2026

Role of Metabolic Reprogramming and Lactylation in Diabetic Nephropathy: Molecular Mechanisms and Therapeutic Prospects – A Narrative Review

in Diabetes: Molecular Mechanisms

Zongtao Li
Yashi Wang
Die Fang
Wenfeng Ye
Xueqin Zhang
Zhiqiang Chen

Frontiers in Endocrinology

139 views

Original Research

Published on 28 Jan 2026

Leptin receptor rs1137101 polymorphism and altered leptin-sOb-R axis contribute to type 2 diabetes risk in Gujarat population

in Diabetes: Molecular Mechanisms

Nishant Parmar
Nirali Rathwa
Roma Patel
Sayantani Pramanik Palit
Naisargi Patel
Satyashree Shetty
Mitesh Dwivedi
Rasheedunnisa Begum
A.V. Ramachandran

Frontiers in Endocrinology

doi 10.3389/fendo.2026.1693265

572 views

Review

Published on 28 Jan 2026

Glucolipid metabolic disorders and ferroptosis in diabetic ulcers: pathogenic crossroads and therapeutic opportunities

in Diabetes: Molecular Mechanisms

Zaiying Yeerbao
Xinxi Li
Lei Zhang
Guoli Du
Jingdong Tang
Shuai Jiang
Xiangxiang Ru
Donglin Li
Dilinuerkezi Abulimiti
Li Chen

Frontiers in Endocrinology

doi 10.3389/fendo.2026.1760943

540 views

Original Research

Accepted on 26 Jan 2026

Early Pregnancy Biomarkers for Gestational Diabetes Mellitus Prediction: A Systematic Review and Meta-Analysis of Routine Laboratory, Metabolic, and Inflammatory Markers

in Diabetes: Molecular Mechanisms

Wenhui Li
Shengjuan Jiang
Hailin Xie
Li Tong

Frontiers in Endocrinology

186 views

Original Research

Accepted on 20 Jan 2026

Metabolomics Identifies Chenodeoxycholic Acid as a Protective Factor in Diabetic Foot Ulcers

in Diabetes: Molecular Mechanisms

Li Ying
Ran Guo
Lu Lv
Tao Jiang
Chenning Zhang
Jiangying Chang
Keyan Hu
Huifang Peng
Lulu Chen
Ran Chen

Frontiers in Endocrinology

155 views

Original Research

Published on 19 Jan 2026

Extracellular matrix from decellularized porcine organs as scaffolds for insulin-secreting cells and pancreatic islets

in Diabetes: Molecular Mechanisms

Vignesh Dhandapani
Pakindame Boabekoa
Patrick Vermette

Frontiers in Endocrinology

doi 10.3389/fendo.2025.1722536

827 views

Mini Review

Published on 15 Jan 2026

Mondo family proteins in diabetes

in Diabetes: Molecular Mechanisms

Sandeep Kumar Barodia
Maria B. Grant
Marina S. Gorbatyuk

Frontiers in Endocrinology

doi 10.3389/fendo.2025.1745162

921 views

Editorial

Published on 15 Jan 2026

Editorial: Advances in β-cell development & regeneration

in Diabetes: Molecular Mechanisms

Santiago A. Rodríguez-Seguí
Meritxell Rovira
George K. Gittes

Frontiers in Endocrinology

doi 10.3389/fendo.2026.1765933

956 views

Systematic Review

Accepted on 12 Jan 2026

Type 2 Diabetes Mellitus Associated microRNAs in Tuberculosis Susceptibility: A Systematic Review and Bioinformatic Analysis

in Diabetes: Molecular Mechanisms

Claudia Carranza
Rodolfo Chavez-Dominguez
Mercedes Viettri
Martha Torres
Itzel A. Corona-Galvan
Emilio Hernández
Mauricio Castañón-Arreola

Frontiers in Endocrinology

307 views

Original Research

Published on 12 Jan 2026

Transcriptome analysis and RT-qPCR validation of mitophagy-related key genes in the progression of diabetic retinopathy

in Diabetes: Molecular Mechanisms

Yifan Zhang
Liangjie Niu
Huika Xia
Jianmin Wang

Frontiers in Endocrinology

doi 10.3389/fendo.2025.1733368

737 views

Original Research

Published on 07 Jan 2026

Abdominal versus femoral subcutaneous fat gene expression in non-obese insulin resistant individuals

in Diabetes: Molecular Mechanisms

Saif Badran
Shamma Almuraikhy
Maha Alser
Khaled Naja
Najeha Anwardeen
Hanan H. Abunada
Mohamed Badie Ahmed
Salma Jarrar
Ghanem Aljassem
Sara Iskeirjeh

Frontiers in Endocrinology

doi 10.3389/fendo.2025.1684761

1,120 views

Review

Published on 06 Jan 2026

Regulatory T cell dysfunction and immunotherapeutic breakthroughs in type 1 diabetes

in Diabetes: Molecular Mechanisms

Kuang-Ji Zhou
Shan-Jie Rong
Yue-Chen Liu
Fei Sun
Ting Wang
Qi-Lin Yu
Cong-Yi Wang

Frontiers in Endocrinology

doi 10.3389/fendo.2025.1740102

1,483 views

851 articles

articles

Effects and interactive effects of high-altitude environment on metabolism in normal and diabetic populations: a comparative metabolomics study

Lipoprotein-associated phospholipase A2 and complications of diabetes mellitus: a systematic review and meta-analysis

TangShenWeiNing formula alleviates diabetic kidney disease by inhibiting ferroptosis via AMPK pathway in renal tubular epithelial cells

Mechanisms and applications of natural plant ingredients in modulating amino acid metabolism for the improvement of diabetic retinopathy: a review

Inflammatory markers associated with albuminuria and early atherosclerosis in type 2 diabetic kidney disease: a cross-sectional study

The SGLT2 inhibitor checklist: a comprehensive review of perioperative and acute phase safety management

Clinical parameters and emerging biomarkers of partial remission in pediatric type 1 diabetes: a systematic review

Aerobic exercise and MOTS-c attenuate diabetic myocardial fibrosis via inhibition of the THBS1/TGF-β signaling pathway

Ferroptosis in diabetic retinopathy: from pathogenic mechanisms to translational prospects

The Role of PYY in Improving Insulin Resistance

Endoplasmic Reticulum Stress in Skeletal Muscle Dysfunction of Type 2 Diabetes: Mechanisms and Therapeutic Implications

Identification of maturity-onset diabetes of the young through targeted next-generation sequencing in Thai patients with atypical diabetes in real-world practice

Role of Metabolic Reprogramming and Lactylation in Diabetic Nephropathy: Molecular Mechanisms and Therapeutic Prospects – A Narrative Review

Leptin receptor rs1137101 polymorphism and altered leptin-sOb-R axis contribute to type 2 diabetes risk in Gujarat population

Glucolipid metabolic disorders and ferroptosis in diabetic ulcers: pathogenic crossroads and therapeutic opportunities

Early Pregnancy Biomarkers for Gestational Diabetes Mellitus Prediction: A Systematic Review and Meta-Analysis of Routine Laboratory, Metabolic, and Inflammatory Markers

Metabolomics Identifies Chenodeoxycholic Acid as a Protective Factor in Diabetic Foot Ulcers

Extracellular matrix from decellularized porcine organs as scaffolds for insulin-secreting cells and pancreatic islets

Mondo family proteins in diabetes

Editorial: Advances in β-cell development & regeneration

Type 2 Diabetes Mellitus Associated microRNAs in Tuberculosis Susceptibility: A Systematic Review and Bioinformatic Analysis

Transcriptome analysis and RT-qPCR validation of mitophagy-related key genes in the progression of diabetic retinopathy

Abdominal versus femoral subcutaneous fat gene expression in non-obese insulin resistant individuals

Regulatory T cell dysfunction and immunotherapeutic breakthroughs in type 1 diabetes