Frontiers in Endocrinology | Diabetes: Molecular Mechanisms

Perspective

Accepted on 26 Jun 2025

Editorial Perspective: Predictors of Powerhouse: A Perspective of Mitochondrial Biomarkers in Type 2 Diabetes

in Diabetes: Molecular Mechanisms

Mónica Muñoz-Úbeda
Surjya Narayan Dash

Frontiers in Endocrinology

doi 10.3389/fendo.2025.1595557

Review

Accepted on 25 Jun 2025

Mechanisms and Therapeutics of Insulin Signaling Transduction Genes in Diabetic Cardiomyopathy: A Comprehensive Updated Review

in Diabetes: Molecular Mechanisms

Yufeng He
Xi Yang
Xinghui He
Guoshuang Wang
Chuang Li
Ping Yuan
Chunhong Li

Frontiers in Endocrinology

doi 10.3389/fendo.2025.1589695

Original Research

Published on 25 Jun 2025

A murine model of gestational diabetes reveals MASLD risk and alterations in markers of hepatic mitochondrial metabolism

in Diabetes: Molecular Mechanisms

Grace E. Shryack
Alexa A. Krause
Simone Hernandez Ruano
Laura C. Schulz
Kathleen A. Pennington
R. Scott Rector

Frontiers in Endocrinology

doi 10.3389/fendo.2025.1498764

327 views

Review

Accepted on 23 Jun 2025

Immune Inflammation and Metabolic Interactions in the Pathogenesis of Diabetic Nephropathy

in Diabetes: Molecular Mechanisms

Guangjian Hou
Youzi Dong
Yue-Hua Jiang
Zhao Wenbo
Le Zhou
Shengnan Cao
Wei Li

Frontiers in Endocrinology

doi 10.3389/fendo.2025.1602594

Mini Review

Accepted on 20 Jun 2025

Targeting Advanced Glycation End Products: Potential Therapeutic Approaches for Mitigating Diabetic Intervertebral Disc Degeneration?

in Diabetes: Molecular Mechanisms

Luyang Wang
Qipeng Shao
Haiyang Wu
Cheng Li

Frontiers in Endocrinology

doi 10.3389/fendo.2025.1618984

123 views

Original Research

Published on 20 Jun 2025

Integrated transcriptomic, proteomic, and metabolomic analysis unveils key roles of protein and nucleic acid interactions in diabetic ulcer pathogenesis

in Diabetes: Molecular Mechanisms

Yongpan Lu
Hairui Gao
Sen Wang
Han Xu
Zhiyu Chen
Yixin Zhang
Yunfei Gu
Xiaomei Sun

Frontiers in Endocrinology

doi 10.3389/fendo.2025.1574858

370 views

Original Research

Accepted on 19 Jun 2025

Shared diagnostic genes and potential mechanism between intervertebral disc degeneration and diabetes mellitus revealed by integrated transcriptomic analysis and machine learning

in Diabetes: Molecular Mechanisms

Bao Song
WanLi Zhang

Frontiers in Endocrinology

doi 10.3389/fendo.2025.1576826

201 views

Mini Review

Published on 19 Jun 2025

Harnessing beta-cell replication: advancing molecular insights to regenerative therapies in diabetes

in Diabetes: Molecular Mechanisms

Rupangi C. Vasavada
Sangeeta Dhawan

Frontiers in Endocrinology

doi 10.3389/fendo.2025.1612576

477 views

Editorial

Published on 18 Jun 2025

Editorial: Dietary and nutrigenetic contributors to metabolic syndrome

in Diabetes: Molecular Mechanisms

Anoop Arunagiri
Maroof Alam
Erez Dror
Melkam A. Kebede

Frontiers in Endocrinology

doi 10.3389/fendo.2025.1632753

457 views

Systematic Review

Accepted on 17 Jun 2025

Data Mining-based Analysis to Explore the Application of an Animal Model of Diabetic Gastroparesis

in Diabetes: Molecular Mechanisms

Yushan Fan
Hui † Xu
Fu-Rui Miao
Yu-Jun He

Frontiers in Endocrinology

doi 10.3389/fendo.2025.1612473

140 views

Original Research

Published on 17 Jun 2025

Metabolic adaptation to acute metabolic stress via PFKFB3 upregulation in rodent beta cells

in Diabetes: Molecular Mechanisms

Koki Chiba
Hiroshi Nomoto
Rimi Izumihara
Xinxin Zhang
Hiraku Kameda
Akinobu Nakamura
Tatsuya Atsumi

Frontiers in Endocrinology

doi 10.3389/fendo.2025.1552700

455 views

Original Research

Published on 17 Jun 2025

Assessment of reconstruction accuracy for under-sampled 31P-MRS data using compressed sensing and a low rank Hankel matrix completion approach

in Diabetes: Molecular Mechanisms

Jossian A. García
Michael D. Noseworthy
Alejandro Santos-Díaz

Frontiers in Endocrinology

doi 10.3389/fendo.2025.1581328

429 views

Original Research

Accepted on 13 Jun 2025

Interleukin-4 prevents increased endothelial permeability by inducing pericyte survival and modulating microglial responses in diabetic retinopathy

in Diabetes: Molecular Mechanisms

Jang-Hyuk Yun

Frontiers in Endocrinology

doi 10.3389/fendo.2025.1609796

151 views

Review

Published on 11 Jun 2025

Targeting programmed cell death pathways: emerging therapeutic strategies for diabetic kidney disease

in Diabetes: Molecular Mechanisms

Lin Wang
Shaowei Ding
Yuxin Hu
Jiaming Su
Gegongming Zhu
Hanzhang Hong
Baoluo Hou
Zhaoxi Dong
Zeyu Xue
Jiayi Wang

Frontiers in Endocrinology

doi 10.3389/fendo.2025.1513895

579 views

Review

Accepted on 03 Jun 2025

Targeting Gut Microbiota for Diabetic Nephropathy Treatment: Probiotics, Dietary Interventions, and Fecal Microbiota Transplantation

in Diabetes: Molecular Mechanisms

Xiaoran Wang
Xinyin Liu
Fanghong Gong
Yan Jiang
Canwei Zhang
Wei Zhou
Wen Zhang

Frontiers in Endocrinology

doi 10.3389/fendo.2025.1621968

217 views

Review

Accepted on 03 Jun 2025

Evaluating the impact of lipids in isolated islet research

in Diabetes: Molecular Mechanisms

Jamie William Joseph
Emelien M Jentz

Frontiers in Endocrinology

doi 10.3389/fendo.2025.1548596

116 views