Frontiers in Gastroenterology | Therapy in Gastroenterology

Case Report

Published on 16 Jun 2026

Infliximab as ultima ratio in a case of refractory non-Crohn’s disease complex fistula system: case report and mini-review of the literature

in Therapy in Gastroenterology

Nada Agbariah
Matthias Kis
Christine Manser
Luc Biedermann
Gerhard Rogler

Frontiers in Gastroenterology

doi 10.3389/fgstr.2026.1815049

376 views

Review

Accepted on 05 Jun 2026

EUS-guided transmural treatment of afferent loop syndrome: a systematic review and meta-analysis

in Therapy in Gastroenterology

Thomas Balanis
Michael Doulberis
Radu Tutuian

Frontiers in Gastroenterology

572 views

Original Research

Accepted on 22 May 2026

Clinical study on the screening of biomarkers for Crohn's disease based on blood metabolomics

in Therapy in Gastroenterology

Tongyuan Lin
Xianhong Hu
Kaifei Yuan
Ping Lin
SiYuan Li
Li Cui
YuanYuan Wang
Ping Liu
Yong Yang

Frontiers in Gastroenterology

391 views

Systematic Review

Accepted on 20 May 2026

Efficacy and Safety of Linaclotide Combined with Polyethylene Glycol for Bowel Preparation in Patients with Constipation: A Meta-analysis

in Therapy in Gastroenterology

Guoli Li
Hongfang Zhang
Lamei Li
Yun Huang

Frontiers in Gastroenterology

414 views

Original Research

Accepted on 18 May 2026

A Real-World Assessment of Healthcare Resource Utilization Following IBS-Smart© and Trio-Smart© Testing in Patients with Suspected Irritable Bowel Syndrome

in Therapy in Gastroenterology

Leonard Weinstock
William Bradley Salt, II MD
Lynn Cherry
Christopher Tyson
Raf Magar

Frontiers in Gastroenterology

448 views

Review

Published on 18 May 2026

GLP-1 and GLP-2 as intestinal reparative therapies in inflammatory bowel disease: mechanisms, translation, and clinical opportunity

in Therapy in Gastroenterology

Joseph J. Lee
Pratikiran Bajgain
Amy L. Lightner

Frontiers in Gastroenterology

doi 10.3389/fgstr.2026.1790420

1,316 views

Original Research

Published on 27 Apr 2026

Current status of 5-aminosalicylic acid in Crohn’s disease treatment: a nationwide survey and analysis of perspectives and practice patterns among inflammatory bowel disease physicians

in Therapy in Gastroenterology

Yuanli Li
Changxin Chen
Chengdang Wang

Frontiers in Gastroenterology

doi 10.3389/fgstr.2026.1783772

1,291 views

Brief Research Report

Published on 01 Apr 2026

Positioning double-balloon enteroscopy in the diagnostic algorithm for suspected small bowel Crohn’s disease: a retrospective analysis of decision-making at a tertiary referral centre

in Therapy in Gastroenterology

Thomas Sheehan
Cormac Hegarty
Roisin Connaughton
Barry Hall
Orlaith B. Kelly

Frontiers in Gastroenterology

doi 10.3389/fgstr.2026.1699553

1,011 views
1 citation

Original Research

Accepted on 23 Mar 2026

Eosinophilic Esophagitis in Italy: An Expert Panel Opinion

in Therapy in Gastroenterology

Salvatore Oliva
Edoardo Savarino
Matteo Fassan
Pierfrancesco Visaggi
Flavio Labriola
Martina Mainetti
Maria Elena Filice
Sabina Martini
Daria Ilenia Lucci
Alessandro Pellegrinelli

Frontiers in Gastroenterology

795 views

Systematic Review

Published on 26 Feb 2026

Role of thalidomide in angiodysplasia-related gastrointestinal bleeding: a systematic review

in Therapy in Gastroenterology

Junaid Khan
Amna Yousaf Shah
Aamir Asif Khan
Ruqaiya Shahid Raja
Zubair Ahmed
Mahad Shahid Raja
Simona Eng
Qamar Iqbal

Frontiers in Gastroenterology

doi 10.3389/fgstr.2026.1669563

1,138 views

Review

Published on 30 Jan 2026

Advancing therapeutic frontiers: a pipeline of novel drugs for UC management

in Therapy in Gastroenterology

Luisa Bertin
Alessandro Massano
Carlo Redavid
Marco Scarpa
Cesare Ruffolo
Imerio Angriman
Andrea Buda
Fabiana Zingone
Brigida Barberio
Edoardo Vincenzo Savarino

Frontiers in Gastroenterology

doi 10.3389/fgstr.2026.1747118

35,266 views
2 citations

Review

Published on 31 Oct 2025

Parental and perinatal risk factors associated with onset of IBD: a systematic literature review and meta-analysis

in Therapy in Gastroenterology

Kristian Paul Mallon
Ciara McBride
Colm Antoine O Morain
Glen A. Doherty
Richeal Burns

Frontiers in Gastroenterology

doi 10.3389/fgstr.2025.1621215

2,010 views

Review

Published on 07 Oct 2025

A multidisciplinary approach to the management of disorders of gut-brain interaction: psychopharmacology, psychotherapy, and diet

in Therapy in Gastroenterology

Francisco J. Barrera Flores
José Adrián Guerrero Tamez
Tatiana Winkelman
Regina Barrera Flores
Elizabeth N. Madva

Frontiers in Gastroenterology

doi 10.3389/fgstr.2025.1637172

5,877 views
2 citations

Case Report

Published on 18 Sep 2025

A case report of adult congenital intestinal malrotation

in Therapy in Gastroenterology

Yu Gao
Xiaobiao Song
Qiang Song

Frontiers in Gastroenterology

doi 10.3389/fgstr.2025.1643128

2,782 views
1 citation

Original Research

Published on 11 Sep 2025

The IBD-disk accurately assesses disability and psychological burden at IBD diagnosis and predicts adverse outcomes in both UC and Crohn’s disease during the first year of treatment: a prospective observational cohort study

in Therapy in Gastroenterology

Peter Rimmer
Viorelia Stoica
Maryam Ibrahim
Asima Javed
Karl Hazel
Michael Owusu
Daniel Regan-Komito
Rachel Cooney
Asif J. Iqbal
Iain Chapple

Frontiers in Gastroenterology

doi 10.3389/fgstr.2025.1642061

3,002 views

Original Research

Published on 10 Sep 2025

Alterations in serum and intestinal ACE2 in Inflammatory Bowel Disease and the impact of inflammation

in Therapy in Gastroenterology

Fiona Jones
Ciara Egan
Miriam Tosetto
Moritz Strowitzki
Sarah J. Kierans
Catherine Rowan
Margaret Walshe
Elizabeth Ryan
Juliette Sheridan
Garret Cullen

Frontiers in Gastroenterology

doi 10.3389/fgstr.2025.1590646

2,172 views

Brief Research Report

Published on 25 Aug 2025

Evaluating bowel preparation tolerability in IBD: a phase 3 post-hoc comparison of mannitol and PEG-ASC

in Therapy in Gastroenterology

Gian Eugenio Tontini
Alessandro Rimondi
Flavio Caprioli
Giovanni Aldinio
Luca Pastorelli
Franco Radaelli
Cristiano Spada
Maurizio Vecchi

Frontiers in Gastroenterology

doi 10.3389/fgstr.2025.1630479

2,498 views

Case Report

Published on 19 Aug 2025

Case Report: Rapid resolution of fever after initiation of third-line rescue treatment with upadacitinib for acute severe ulcerative colitis in two young men

in Therapy in Gastroenterology

Dan Pinzaru
Martin Kreysing
Tony Lesmeister
Miriam Schwandner
Patrick Michl
Annika Gauss

Frontiers in Gastroenterology

doi 10.3389/fgstr.2025.1626455

2,191 views

Review

Published on 25 Jul 2025

Gastrointestinal endoscopy for intestinal dysplasia and neoplasia detection and management in Crohn’s disease: when and how?

in Therapy in Gastroenterology

Tommaso Pessarelli
Alessandra Piagnani
Gian Eugenio Tontini
Irene Maria Bambina Bergna
Arnaldo Amato

Frontiers in Gastroenterology

doi 10.3389/fgstr.2025.1626610

2,917 views

Original Research

Published on 15 Jul 2025

Curcumin–QingDai combination for patients with active Crohn’s disease: a retrospective, real-world multicenter cohort study

in Therapy in Gastroenterology

Nir Salomon
Maayan Marom
Safwat Odeh
Madlen Molnar
Ariella Bar-Gil Shitrit
Omri Nayshool
Bella Ungar
Shomron Ben-Horin
Tova Rainis

Frontiers in Gastroenterology

doi 10.3389/fgstr.2025.1602541

5,438 views
1 citation

Original Research

Published on 02 Jul 2025

Proteomic profile of human colon organoids: effects of a multi-mineral intervention alone and in the presence of pro-inflammatory and anti-inflammatory treatments

in Therapy in Gastroenterology

Muhammad Nadeem Aslam
Shannon D. McClintock
Gillian Moraga
Daniyal M. Nadeem
Isabelle Harber
James Varani

Frontiers in Gastroenterology

doi 10.3389/fgstr.2025.1592669

3,303 views
2 citations

Original Research

Published on 24 Jan 2025

Prevalence and characteristics of gastrointestinal disorders, medication use, and diagnostic interventions in pediatric patients with cystic fibrosis: a nested case–control analysis from the TriNetX EMR-derived global research network real-world dataset

in Therapy in Gastroenterology

Carolena Trocchia
Maua Mosha
Bailey Hamner
Neil Goldenberg
Racha Khalaf

Frontiers in Gastroenterology

doi 10.3389/fgstr.2024.1489876

2,992 views
3 citations

Original Research

Published on 13 Dec 2024

A new Simple Endoscopic Score for Ulcerative Colitis – the SES-UC

in Therapy in Gastroenterology

Viktoria Bergqvist
Peter Gedeon
Erik Hertervig
Jan Marsal

Frontiers in Gastroenterology

doi 10.3389/fgstr.2024.1468394

5,349 views
1 citation

Review

Published on 25 Nov 2024

Acute severe ulcerative colitis: using JAK-STAT inhibitors for improved clinical outcomes

in Therapy in Gastroenterology

Shruthi Karthikeyan
Chetan Ambastha
Kian Keyashian

Frontiers in Gastroenterology

doi 10.3389/fgstr.2024.1488288

5,133 views

51 articles

articles

Infliximab as ultima ratio in a case of refractory non-Crohn’s disease complex fistula system: case report and mini-review of the literature

EUS-guided transmural treatment of afferent loop syndrome: a systematic review and meta-analysis

Clinical study on the screening of biomarkers for Crohn's disease based on blood metabolomics

Efficacy and Safety of Linaclotide Combined with Polyethylene Glycol for Bowel Preparation in Patients with Constipation: A Meta-analysis

A Real-World Assessment of Healthcare Resource Utilization Following IBS-Smart© and Trio-Smart© Testing in Patients with Suspected Irritable Bowel Syndrome

GLP-1 and GLP-2 as intestinal reparative therapies in inflammatory bowel disease: mechanisms, translation, and clinical opportunity

Current status of 5-aminosalicylic acid in Crohn’s disease treatment: a nationwide survey and analysis of perspectives and practice patterns among inflammatory bowel disease physicians

Positioning double-balloon enteroscopy in the diagnostic algorithm for suspected small bowel Crohn’s disease: a retrospective analysis of decision-making at a tertiary referral centre

Eosinophilic Esophagitis in Italy: An Expert Panel Opinion

Role of thalidomide in angiodysplasia-related gastrointestinal bleeding: a systematic review

Advancing therapeutic frontiers: a pipeline of novel drugs for UC management

Parental and perinatal risk factors associated with onset of IBD: a systematic literature review and meta-analysis

A multidisciplinary approach to the management of disorders of gut-brain interaction: psychopharmacology, psychotherapy, and diet

A case report of adult congenital intestinal malrotation

The IBD-disk accurately assesses disability and psychological burden at IBD diagnosis and predicts adverse outcomes in both UC and Crohn’s disease during the first year of treatment: a prospective observational cohort study

Alterations in serum and intestinal ACE2 in Inflammatory Bowel Disease and the impact of inflammation

Evaluating bowel preparation tolerability in IBD: a phase 3 post-hoc comparison of mannitol and PEG-ASC

Case Report: Rapid resolution of fever after initiation of third-line rescue treatment with upadacitinib for acute severe ulcerative colitis in two young men

Gastrointestinal endoscopy for intestinal dysplasia and neoplasia detection and management in Crohn’s disease: when and how?

Curcumin–QingDai combination for patients with active Crohn’s disease: a retrospective, real-world multicenter cohort study

Proteomic profile of human colon organoids: effects of a multi-mineral intervention alone and in the presence of pro-inflammatory and anti-inflammatory treatments

Prevalence and characteristics of gastrointestinal disorders, medication use, and diagnostic interventions in pediatric patients with cystic fibrosis: a nested case–control analysis from the TriNetX EMR-derived global research network real-world dataset

A new Simple Endoscopic Score for Ulcerative Colitis – the SES-UC

Acute severe ulcerative colitis: using JAK-STAT inhibitors for improved clinical outcomes