Frontiers in Genetics | Pharmacogenetics and Pharmacogenomics

Perspective

Accepted on 05 Oct 2026

The Potential Role of Large Language Models in Addressing Phenoconversion in Pharmacogenomics

in Pharmacogenetics and Pharmacogenomics

Augusto Garcia-Agundez
José A G Agúndez

Frontiers in Genetics

125 views

Original Research

Published on 26 Aug 2026

Development of a PCR-based technique for genotyping UGT1A1 gene and distribution of rs3064744 alleles in the Russian population

in Pharmacogenetics and Pharmacogenomics

M. A. Vinokurov
K. O. Mironov
M. S. Yurchuk
V. G. Akimkin

Frontiers in Genetics

doi 10.3389/fgene.2026.1899437

1,215 views

Opinion

Published on 18 Aug 2026

Repositioning candidate gene approaches in the post-GWAS era: a clinical perspective from psychiatric pharmacogenetics

in Pharmacogenetics and Pharmacogenomics

Milica Pjevac
Jurij Bon
Vita Dolžan

Frontiers in Genetics

doi 10.3389/fgene.2026.1828563

1,671 views

Brief Research Report

Published on 30 Mar 2026

Pharmacist workforce training in pharmacogenomics with a focus on rural and underserved areas

in Pharmacogenetics and Pharmacogenomics

Moataz Mohamed
Pamala A. Jacobson
Alyssa Johnson
Jacob Tyler Brown

Frontiers in Genetics

doi 10.3389/fgene.2026.1794122

2,158 views

Brief Research Report

Published on 27 Feb 2026

Allelic diversity of the pharmacogenes CYP2D6 and CYP2C19 in Māori from Te Tairāwhiti, Aotearoa New Zealand

in Pharmacogenetics and Pharmacogenomics

Leonie Hitchman
Te Whetu Aarahi Kerekere
Allison L. Miller
Elizabeth Goodin
Caroline Koia
Huti Watson
Frances King
Stephen P. Robertson
Phillip Wilcox
Martin A. Kennedy

Frontiers in Genetics

doi 10.3389/fgene.2026.1668409

2,818 views
1 citation

Editorial

Published on 16 Feb 2026

Editorial: Integrating genetics and proteomics for drug discovery

in Pharmacogenetics and Pharmacogenomics

Karunakaran Kalesh
Liang Xue

Frontiers in Genetics

doi 10.3389/fgene.2026.1806492

1,891 views

Original Research

Published on 12 Feb 2026

Structural pharmacogenomics of drug-associated SNPs in oral squamous cell carcinoma

in Pharmacogenetics and Pharmacogenomics

Punya Sunil
K. C. Ananth Kumar
A. I. Ananthakrishnan
Sebanti Gupta
Ranajit Das

Frontiers in Genetics

doi 10.3389/fgene.2026.1666142

2,940 views
2 citations

Review

Published on 02 Jan 2026

The power and the promise of epigenetic drugs in oncology

in Pharmacogenetics and Pharmacogenomics

Thalita Basso Scandolara
Isabelle Vasconcelos Menegoy Siqueira
Luis Felipe Ribeiro Pinto
Sheila Coelho Soares-Lima

Frontiers in Genetics

doi 10.3389/fgene.2025.1622115

5,742 views
8 citations

Case Report

Published on 01 Dec 2025

Case Report: Pitfalls in CF screening – targeted variant analysis can cause misleading results and therapy recommendations

in Pharmacogenetics and Pharmacogenomics

Maike Karnstedt
Simone Ahting
Sophie Behrendt
Maike vom Hove
Julia Hentschel

Frontiers in Genetics

doi 10.3389/fgene.2025.1693573

2,861 views
1 citation

Original Research

Published on 23 Oct 2025

aiGeneR 3.0: an enhanced deep network model for resistant strain identification and multi-drug resistance prediction in Escherichia coli causing urinary tract infection using next-generation sequencing data

in Pharmacogenetics and Pharmacogenomics

Debasish Swapnesh Kumar Nayak
Abhilash Pati
Amrutanshu Panigrahi
Mudassir Khan
Bayan Alabdullah
Santanu Kumar Sahoo
Bibhuprasad Sahu
Abrar Almjally
Saurav Mallik
Tripti Swarnkar

Frontiers in Genetics

doi 10.3389/fgene.2025.1651917

4,027 views
3 citations

Original Research

Published on 25 Sep 2025

Concordance of an in-house 2-steps PCR-SSP and nanopore sequencing for HLA-B57:01 and HLA-B58:01 typing: a comparative study

in Pharmacogenetics and Pharmacogenomics

Nattapong Intharuangrung
Chonticha Sirikul
Pattaraporn Nimsamer
Thidathip Wongsurawat
Auttachai Saejia
Nampeung Anukul

Frontiers in Genetics

doi 10.3389/fgene.2025.1649990

6,203 views

Correction

Published on 08 Jul 2025

Correction: Clinical impact of pharmacogenomics in pediatric care: insights extracted from clinical exome sequencing

in Pharmacogenetics and Pharmacogenomics

Simran Maggo
Yachen Pan
Dejerianne Ostrow
Jenny Q. Nguyen
Jaclyn A. Biegel
Matthew A. Deardorff
Xiaowu Gai

Frontiers in Genetics

doi 10.3389/fgene.2025.1639666

3,311 views
1 citation

Review

Published on 24 Jun 2025

Gene polymorphisms associated with immunosuppressant adverse effects in systemic lupus erythematosus: a narrative review

in Pharmacogenetics and Pharmacogenomics

Siva Hamdani
Laniyati Hamijoyo
Riezki Amalia
Melisa I. Barliana

Frontiers in Genetics

doi 10.3389/fgene.2025.1594648

7,816 views
3 citations

Case Report

Published on 17 Jun 2025

Case Report: Successful late-line pralsetinib treatment in an ALK-rearranged lung adenocarcinoma patient with KIF5B-RET fusion resistant to alectinib

in Pharmacogenetics and Pharmacogenomics

Feng Jin
Chenyang Wang
Fang Yang
Shubin Wang
Fen Wang

Frontiers in Genetics

doi 10.3389/fgene.2025.1569912

5,018 views
1 citation

Original Research

Published on 04 Jun 2025

NOS3 rs3918188C>A is associated with susceptibility to resistant hypertension while CES1 genetic variation was not associated with resistant hypertension among South Africans

in Pharmacogenetics and Pharmacogenomics

Jonathan N. Katsukunya
Revina Naicker
Nyarai D. Soko
Dirk Blom
Phumla Sinxadi
Emile R. Chimusa
Brian Rayner
Erika Jones
Collet Dandara

Frontiers in Genetics

doi 10.3389/fgene.2025.1608423

5,331 views
2 citations

Original Research

Published on 29 May 2025

Clinical impact of pharmacogenomics in pediatric care: insights extracted from clinical exome sequencing

in Pharmacogenetics and Pharmacogenomics

Simran Maggo
Yachen Pan
Dejerianne Ostrow
Jenny Q. Nguyen
Jaclyn A. Biegel
Matthew A. Deardorff
Xiaowu Gai

Frontiers in Genetics

doi 10.3389/fgene.2025.1574325

6,867 views
2 citations

Original Research

Published on 20 May 2025

Lack of association between genetic variations in CYP3A5 and blood pressure or hypertension risk in the UK biobank

in Pharmacogenetics and Pharmacogenomics

Pia Leibold
Christelle Lteif
Julio D. Duarte

Frontiers in Genetics

doi 10.3389/fgene.2025.1490863

3,626 views
1 citation

Review

Published on 30 Apr 2025

Leveraging long-read sequencing technologies for pharmacogenomic testing: applications, analytical strategies, challenges, and future perspectives

in Pharmacogenetics and Pharmacogenomics

Alireza Tafazoli
Mahboobeh Hemmati
Mahboobeh Rafigh
Maliheh Alimardani
Faeze Khaghani
Michał Korostyński
Jason H. Karnes

Frontiers in Genetics

doi 10.3389/fgene.2025.1435416

8,693 views
17 citations

Original Research

Published on 17 Apr 2025

Correlation between gene polymorphisms and perioperative analgesia in patients undergoing gynecological surgery

in Pharmacogenetics and Pharmacogenomics

Meng Cai
Xiaofeng Lei
Lin Gan
Jing Li
Jin Yu

Frontiers in Genetics

doi 10.3389/fgene.2025.1509042

3,343 views

Systematic Review

Published on 20 Feb 2025

Correlation and clinical significance of GSTP1 hypermethylation in hepatocellular carcinoma: a systematic review and meta-analysis

in Pharmacogenetics and Pharmacogenomics

Pengfei Li
Lei He
Chunxia Zhang
Xinyao Huang
Rong Sun
Yan Zhang
Yan Wang

Frontiers in Genetics

doi 10.3389/fgene.2025.1543261

4,767 views
7 citations

Original Research

Published on 23 Oct 2024

Roles of NR1I3 and NR1H4 polymorphisms in the susceptibility to antituberculosis drug-induced liver injury in China: a case‒control study

in Pharmacogenetics and Pharmacogenomics

Xiaoyan Xu
Ruina Chen
Lihuan Lu
Jingru Cheng
Xiaomin He
Hongqiu Pan
Meiling Zhang
Honggang Yi
Shaowen Tang

Frontiers in Genetics

doi 10.3389/fgene.2024.1428319

3,773 views
1 citation

Original Research

Published on 11 Sep 2024

Ninein, a candidate gene for ethanol anxiolysis, shows complex exon-specific expression and alternative splicing differences between C57BL/6J and DBA/2J mice

in Pharmacogenetics and Pharmacogenomics

E. R. Gnatowski
J. L. Jurmain
M. G. Dozmorov
J. T. Wolstenholme
M. F. Miles

Frontiers in Genetics

doi 10.3389/fgene.2024.1455616

3,002 views
3 citations

Mini Review

Published on 30 Aug 2024

Human sulfotransferase SULT2B1 physiological role and the impact of genetic polymorphism on enzyme activity and pathological conditions

in Pharmacogenetics and Pharmacogenomics

Fatemah A. Alherz

Frontiers in Genetics

doi 10.3389/fgene.2024.1464243

5,903 views
13 citations

Editorial

Published on 20 Aug 2024

Editorial: Utilization of pharmacogenomics in clinical practice

in Pharmacogenetics and Pharmacogenomics

Apostolos Papachristos
Jessica Cusato
Sujit Nair
Simran Maggo
Vijayaprakash Suppiah

Frontiers in Genetics

doi 10.3389/fgene.2024.1470698

3,026 views
1 citation

192 articles

articles

The Potential Role of Large Language Models in Addressing Phenoconversion in Pharmacogenomics

Development of a PCR-based technique for genotyping UGT1A1 gene and distribution of rs3064744 alleles in the Russian population

Repositioning candidate gene approaches in the post-GWAS era: a clinical perspective from psychiatric pharmacogenetics

Pharmacist workforce training in pharmacogenomics with a focus on rural and underserved areas

Allelic diversity of the pharmacogenes CYP2D6 and CYP2C19 in Māori from Te Tairāwhiti, Aotearoa New Zealand

Editorial: Integrating genetics and proteomics for drug discovery

Structural pharmacogenomics of drug-associated SNPs in oral squamous cell carcinoma

The power and the promise of epigenetic drugs in oncology

Case Report: Pitfalls in CF screening – targeted variant analysis can cause misleading results and therapy recommendations

aiGeneR 3.0: an enhanced deep network model for resistant strain identification and multi-drug resistance prediction in Escherichia coli causing urinary tract infection using next-generation sequencing data

Concordance of an in-house 2-steps PCR-SSP and nanopore sequencing for HLA-B57:01 and HLA-B58:01 typing: a comparative study

Correction: Clinical impact of pharmacogenomics in pediatric care: insights extracted from clinical exome sequencing

Gene polymorphisms associated with immunosuppressant adverse effects in systemic lupus erythematosus: a narrative review

Case Report: Successful late-line pralsetinib treatment in an ALK-rearranged lung adenocarcinoma patient with KIF5B-RET fusion resistant to alectinib

NOS3 rs3918188C>A is associated with susceptibility to resistant hypertension while CES1 genetic variation was not associated with resistant hypertension among South Africans

Clinical impact of pharmacogenomics in pediatric care: insights extracted from clinical exome sequencing

Lack of association between genetic variations in CYP3A5 and blood pressure or hypertension risk in the UK biobank

Leveraging long-read sequencing technologies for pharmacogenomic testing: applications, analytical strategies, challenges, and future perspectives

Correlation between gene polymorphisms and perioperative analgesia in patients undergoing gynecological surgery

Correlation and clinical significance of GSTP1 hypermethylation in hepatocellular carcinoma: a systematic review and meta-analysis

Roles of NR1I3 and NR1H4 polymorphisms in the susceptibility to antituberculosis drug-induced liver injury in China: a case‒control study

Ninein, a candidate gene for ethanol anxiolysis, shows complex exon-specific expression and alternative splicing differences between C57BL/6J and DBA/2J mice

Human sulfotransferase SULT2B1 physiological role and the impact of genetic polymorphism on enzyme activity and pathological conditions

Editorial: Utilization of pharmacogenomics in clinical practice

articles

The Potential Role of Large Language Models in Addressing Phenoconversion in Pharmacogenomics

Development of a PCR-based technique for genotyping UGT1A1 gene and distribution of rs3064744 alleles in the Russian population

Repositioning candidate gene approaches in the post-GWAS era: a clinical perspective from psychiatric pharmacogenetics

Pharmacist workforce training in pharmacogenomics with a focus on rural and underserved areas

Allelic diversity of the pharmacogenes CYP2D6 and CYP2C19 in Māori from Te Tairāwhiti, Aotearoa New Zealand

Editorial: Integrating genetics and proteomics for drug discovery

Structural pharmacogenomics of drug-associated SNPs in oral squamous cell carcinoma

The power and the promise of epigenetic drugs in oncology

Case Report: Pitfalls in CF screening – targeted variant analysis can cause misleading results and therapy recommendations

aiGeneR 3.0: an enhanced deep network model for resistant strain identification and multi-drug resistance prediction in Escherichia coli causing urinary tract infection using next-generation sequencing data

Concordance of an in-house 2-steps PCR-SSP and nanopore sequencing for HLA-B*57:01 and HLA-B*58:01 typing: a comparative study

Correction: Clinical impact of pharmacogenomics in pediatric care: insights extracted from clinical exome sequencing

Gene polymorphisms associated with immunosuppressant adverse effects in systemic lupus erythematosus: a narrative review

Case Report: Successful late-line pralsetinib treatment in an ALK-rearranged lung adenocarcinoma patient with KIF5B-RET fusion resistant to alectinib

NOS3 rs3918188C>A is associated with susceptibility to resistant hypertension while CES1 genetic variation was not associated with resistant hypertension among South Africans

Clinical impact of pharmacogenomics in pediatric care: insights extracted from clinical exome sequencing

Lack of association between genetic variations in CYP3A5 and blood pressure or hypertension risk in the UK biobank

Leveraging long-read sequencing technologies for pharmacogenomic testing: applications, analytical strategies, challenges, and future perspectives

Correlation between gene polymorphisms and perioperative analgesia in patients undergoing gynecological surgery

Correlation and clinical significance of GSTP1 hypermethylation in hepatocellular carcinoma: a systematic review and meta-analysis

Roles of NR1I3 and NR1H4 polymorphisms in the susceptibility to antituberculosis drug-induced liver injury in China: a case‒control study

Ninein, a candidate gene for ethanol anxiolysis, shows complex exon-specific expression and alternative splicing differences between C57BL/6J and DBA/2J mice

Human sulfotransferase SULT2B1 physiological role and the impact of genetic polymorphism on enzyme activity and pathological conditions

Editorial: Utilization of pharmacogenomics in clinical practice

Concordance of an in-house 2-steps PCR-SSP and nanopore sequencing for HLA-B57:01 and HLA-B58:01 typing: a comparative study