Frontiers in Genetics | Pharmacogenetics and Pharmacogenomics

Original Research

Published on 20 May 2025

Lack of association between genetic variations in CYP3A5 and blood pressure or hypertension risk in the UK biobank

in Pharmacogenetics and Pharmacogenomics

Pia Leibold
Christelle Lteif
Julio D. Duarte

Frontiers in Genetics

doi 10.3389/fgene.2025.1490863

323 views

Original Research

Accepted on 15 May 2025

NOS3 rs3918188C>A is associated with susceptibility to resistant hypertension while CES1 genetic variation was not associated with resistant hypertension among South Africans

in Pharmacogenetics and Pharmacogenomics

Jonathan N Katsukunya
Revina Naicker
Nyarai Soko
Dirk Jacobus Blom
Phumla Sinxadi
Emile Rugamika Chimusa
Brian Rayner
Erika Jones
Collet Dandara

Frontiers in Genetics

doi 10.3389/fgene.2025.1608423

144 views

Review

Published on 30 Apr 2025

Leveraging long-read sequencing technologies for pharmacogenomic testing: applications, analytical strategies, challenges, and future perspectives

in Pharmacogenetics and Pharmacogenomics

Alireza Tafazoli
Mahboobeh Hemmati
Mahboobeh Rafigh
Maliheh Alimardani
Faeze Khaghani
Michał Korostyński
Jason H. Karnes

Frontiers in Genetics

doi 10.3389/fgene.2025.1435416

1,065 views

Original Research

Accepted on 22 Apr 2025

Clinical Impact of Pharmacogenomics in Pediatric Care: Insights Extracted from Clinical Exome Sequencing

in Pharmacogenetics and Pharmacogenomics

Simran D S Maggo
Yachen Pan
Dejerianne Ostrow
Jenny Nguyen
Jaclyn A Biegel
Matthew A Deardorff
Xiaowu Gai

Frontiers in Genetics

doi 10.3389/fgene.2025.1574325

313 views

Original Research

Published on 17 Apr 2025

Correlation between gene polymorphisms and perioperative analgesia in patients undergoing gynecological surgery

in Pharmacogenetics and Pharmacogenomics

Meng Cai
Xiaofeng Lei
Lin Gan
Jing Li
Jin Yu

Frontiers in Genetics

doi 10.3389/fgene.2025.1509042

685 views

Systematic Review

Published on 20 Feb 2025

Correlation and clinical significance of GSTP1 hypermethylation in hepatocellular carcinoma: a systematic review and meta-analysis

in Pharmacogenetics and Pharmacogenomics

Pengfei Li
Lei He
Chunxia Zhang
Xinyao Huang
Rong Sun
Yan Zhang
Yan Wang

Frontiers in Genetics

doi 10.3389/fgene.2025.1543261

1,265 views

Original Research

Published on 23 Oct 2024

Roles of NR1I3 and NR1H4 polymorphisms in the susceptibility to antituberculosis drug-induced liver injury in China: a case‒control study

in Pharmacogenetics and Pharmacogenomics

Xiaoyan Xu
Ruina Chen
Lihuan Lu
Jingru Cheng
Xiaomin He
Hongqiu Pan
Meiling Zhang
Honggang Yi
Shaowen Tang

Frontiers in Genetics

doi 10.3389/fgene.2024.1428319

1,077 views

Original Research

Published on 11 Sep 2024

Ninein, a candidate gene for ethanol anxiolysis, shows complex exon-specific expression and alternative splicing differences between C57BL/6J and DBA/2J mice

in Pharmacogenetics and Pharmacogenomics

E. R. Gnatowski
J. L. Jurmain
M. G. Dozmorov
J. T. Wolstenholme
M. F. Miles

Frontiers in Genetics

doi 10.3389/fgene.2024.1455616

1,135 views
1 citation

Mini Review

Published on 30 Aug 2024

Human sulfotransferase SULT2B1 physiological role and the impact of genetic polymorphism on enzyme activity and pathological conditions

in Pharmacogenetics and Pharmacogenomics

Fatemah A. Alherz

Frontiers in Genetics

doi 10.3389/fgene.2024.1464243

1,909 views
3 citations

Editorial

Published on 20 Aug 2024

Editorial: Utilization of pharmacogenomics in clinical practice

in Pharmacogenetics and Pharmacogenomics

Apostolos Papachristos
Jessica Cusato
Sujit Nair
Simran Maggo
Vijayaprakash Suppiah

Frontiers in Genetics

doi 10.3389/fgene.2024.1470698

1,150 views

Editorial

Published on 18 Apr 2024

Editorial: The impact of the human genome on interindividual variability in drug response

in Pharmacogenetics and Pharmacogenomics

Yaya Kassogue
Ingrid Fricke-Galindo

Frontiers in Genetics

doi 10.3389/fgene.2024.1401604

1,430 views

Editorial

Published on 03 Apr 2024

Editorial: Molecular targets for anticancer drug discovery and development

in Pharmacogenetics and Pharmacogenomics

Monde Ntwasa
Zodwa Dlamini

Frontiers in Genetics

doi 10.3389/fgene.2024.1374867

1,441 views

Original Research

Published on 05 Jan 2024

Phylogenetic conservation of Trop-2 across species—rodent and primate genomics model anti-Trop-2 therapy for pre-clinical benchmarks

in Pharmacogenetics and Pharmacogenomics

Emanuela Guerra
Marco Trerotola
Valeria Relli
Rossano Lattanzio
Khouloud Boujnah
Nicole Travali
Antonino Moschella
Paolo Todaro
Laura Pierdomenico
Roberta Di Pietro

Frontiers in Genetics

doi 10.3389/fgene.2023.1297367

4,156 views
1 citation

Mini Review

Published on 03 Jan 2024

Moving towards the implementation of pharmacogenetic testing in Quebec

in Pharmacogenetics and Pharmacogenomics

Ling Jing Li
Samuel Legeay
Ann-Lorie Gagnon
Marie-Pier Frigon
Laurence Tessier
Karine Tremblay

Frontiers in Genetics

doi 10.3389/fgene.2023.1295963

3,227 views
3 citations

Original Research

Published on 13 Dec 2023

Whole genome sequence analysis of apparent treatment resistant hypertension status in participants from the Trans-Omics for Precision Medicine program

in Pharmacogenetics and Pharmacogenomics

Nicole D. Armstrong
Vinodh Srinivasasainagendra
Farah Ammous
Themistocles L. Assimes
Amber L. Beitelshees
Jennifer Brody
Brian E. Cade
Yii-Der Ida Chen
Han Chen
Paul S. de Vries

Frontiers in Genetics

doi 10.3389/fgene.2023.1278215

4,284 views
2 citations

Brief Research Report

Published on 28 Nov 2023

Personalized medicine in a community health system: the NorthShore experience

in Pharmacogenetics and Pharmacogenomics

Sean P. David
Henry M. Dunnenberger
Sarah Choi
Allison DePersia
Nadim Ilbawi
Christopher Ward
Dyson T. Wake
Janardan D. Khandekar
Yvette Shannon
Kristen Hughes

Frontiers in Genetics

doi 10.3389/fgene.2023.1308738

4,720 views
6 citations