Frontiers in Genome Editing

Review

Published on 26 Aug 2025

Stem cell and CRISPR/Cas9 gene editing technology in Alzheimer’s disease therapy: from basic research to clinical innovation

Cong He
Baojiang Chen
Ciai Yan
Xiaoqing Zhou

Frontiers in Genome Editing

doi 10.3389/fgeed.2025.1612868

2,616 views

Perspective

Published on 20 Aug 2025

Ethical dimensions and societal implications: ensuring the social responsibility of CRISPR technology

Irfan Biswas

Frontiers in Genome Editing

doi 10.3389/fgeed.2025.1593172

3,174 views

Editorial

Published on 31 Jul 2025

Editorial: Gene editing to achieve Zero Hunger

Shakeel Ahmad
Iqrar Ahmad Rana
Kevin M. Folta
Christian Damian Lorenzo
Sultan Habibullah Khan

Frontiers in Genome Editing

doi 10.3389/fgeed.2025.1632120

2,615 views

Original Research

Published on 24 Jul 2025

CATS: a bioinformatic tool for automated Cas9 nucleases activity comparison in clinically relevant contexts

Ettore Rocchi
Federico Magnani
Gastone Castellani
Antonio Carusillo
Martina Tarozzi

Frontiers in Genome Editing

doi 10.3389/fgeed.2025.1571023

1,485 views

Brief Research Report

Published on 23 Jul 2025

CRISPR-Cas9 editing of TNFAIP3 variants in salivary gland epithelial cells to study Sjögren’s disease pathogenesis

Subhashis Ghosh
Qisheng Tu
Zoe Xiaofang Zhu
Sreelakshmi Panginikkod
Jake Jinkun Chen

Frontiers in Genome Editing

doi 10.3389/fgeed.2025.1625393

1,266 views

Original Research

Published on 02 Jul 2025

Simply cut out – Combining CRISPR/Cas9 RNPs and transiently selected telomere vectors for marker free-gene deletion in Trichoderma atroviride

Mario Gründlinger
Chiara Ellensohn
Leo Drechsel
Ulrike Schreiner
Siebe Pierson
Clara Baldin
Susanne Zeilinger

Frontiers in Genome Editing

doi 10.3389/fgeed.2025.1623963

1,711 views

Methods

Published on 01 Jul 2025

Comprehensive approaches to design efficient gRNA for SDN1-CRISPR/Cas9 genome editing in wheat

Tushadri Singh
H. M. Mamrutha
Rajender Singh
J. P. Jaiswal
Zeenat Wadhwa
Rakesh Kumar
Omvir Singh
O. P. Ahlawat
Ratan Tiwari

Frontiers in Genome Editing

doi 10.3389/fgeed.2025.1579165

2,184 views

Brief Research Report

Published on 30 Jun 2025

DNA-free CRISPR genome editing in raspberry (Rubus idaeus) protoplast through RNP-mediated transfection

Ryan Creeth
Andrew Thompson
Zoltan Kevei

Frontiers in Genome Editing

doi 10.3389/fgeed.2025.1589431

3,575 views

Review

Published on 30 Jun 2025

Genome editing for sustainable agriculture in Peru: advances, potential applications and regulation

Marilu Mestanza
Angel David Hernández-Amasifuen
Alexandra Jherina Pineda-Lázaro
Dennis Eriksson
Juan Carlos Guerrero-Abad

Frontiers in Genome Editing

doi 10.3389/fgeed.2025.1611040

3,465 views

Brief Research Report

Published on 18 Jun 2025

A long shelf-life melon created via CRISPR/Cas9 RNP-based in planta genome editing

Kentaro Sasaki
Kaoru Urano
Naozumi Mimida
Satoko Nonaka
Hiroshi Ezura
Ryozo Imai

Frontiers in Genome Editing

doi 10.3389/fgeed.2025.1623097

2,310 views

Original Research

Published on 04 Jun 2025

Long read sequencing reveals transgene concatemerization and vector sequences integration following AAV-driven electroporation of CRISPR RNP complexes in mouse zygotes

Muhammad W. Luqman
Piroon Jenjaroenpun
Jessica Spathos
Nikhil Shingte
Mitchell Cummins
Pattaraporn Nimsamer
Lars M. Ittner
Thidathip Wongsurawat
Fabien Delerue

Frontiers in Genome Editing

doi 10.3389/fgeed.2025.1582097

3,089 views
1 citation

Review

Published on 03 Jun 2025

Recent developments, challenges and opportunities in genome editing for crop science from a societal perspective

Srividhya Venkataraman
David Zaruk
Kathleen Hefferon

Frontiers in Genome Editing

doi 10.3389/fgeed.2025.1568072

4,129 views

Methods

Published on 30 May 2025

Lentiviral CRISPRa/i in the adult prairie vole brain: modulating neuronal gene expression without DNA cleavage

Meredith K. Loth
Kendall T. Mesch
Celine Herrera-Garcia
Liza E. Brusman
Zoe R. Donaldson

Frontiers in Genome Editing

doi 10.3389/fgeed.2025.1602983

2,044 views
1 citation

Editorial

Published on 22 May 2025

Editorial: Plant breeding innovations—CRISPR as a powerful weapon for agricultural crops

Basavantraya N. Devanna
Yugander Arra
Maganti Sheshu Madhav

Frontiers in Genome Editing

doi 10.3389/fgeed.2025.1623540

3,740 views

Review

Published on 21 May 2025

Base editors in zebrafish: a new era for functional genomics and disease modeling

Yuwen Liu
Chao Li
Yiren Qiu
Sihong Chen
Yijun Luo
Donghua Xiong
Jun Zhao
Jianmin Ye
Xuegeng Wang
Wei Qin

Frontiers in Genome Editing

doi 10.3389/fgeed.2025.1598887

2,996 views
1 citation

Review

Published on 20 May 2025

Genome editing in grain legumes for food security

Joshua Yeboah Asiamah
Sakina Haruna Mahdi
Kusum R. Tamang
Christian Bryan Carson
Prabesh Koirala
Emily Anne Reed
Aaron Tettey Asare
Anu Augustine
Milind B. Ratnaparkhe
Kailash C. Bansal

Frontiers in Genome Editing

doi 10.3389/fgeed.2025.1572292

4,386 views

277 Publications

Volume 7 - 2025

Stem cell and CRISPR/Cas9 gene editing technology in Alzheimer’s disease therapy: from basic research to clinical innovation

Ethical dimensions and societal implications: ensuring the social responsibility of CRISPR technology

Editorial: Gene editing to achieve Zero Hunger

CATS: a bioinformatic tool for automated Cas9 nucleases activity comparison in clinically relevant contexts

CRISPR-Cas9 editing of TNFAIP3 variants in salivary gland epithelial cells to study Sjögren’s disease pathogenesis

Simply cut out – Combining CRISPR/Cas9 RNPs and transiently selected telomere vectors for marker free-gene deletion in Trichoderma atroviride

Comprehensive approaches to design efficient gRNA for SDN1-CRISPR/Cas9 genome editing in wheat

DNA-free CRISPR genome editing in raspberry (Rubus idaeus) protoplast through RNP-mediated transfection

Genome editing for sustainable agriculture in Peru: advances, potential applications and regulation

A long shelf-life melon created via CRISPR/Cas9 RNP-based in planta genome editing

Long read sequencing reveals transgene concatemerization and vector sequences integration following AAV-driven electroporation of CRISPR RNP complexes in mouse zygotes

Recent developments, challenges and opportunities in genome editing for crop science from a societal perspective

Lentiviral CRISPRa/i in the adult prairie vole brain: modulating neuronal gene expression without DNA cleavage

Editorial: Plant breeding innovations—CRISPR as a powerful weapon for agricultural crops

Base editors in zebrafish: a new era for functional genomics and disease modeling

Genome editing in grain legumes for food security