Frontiers in Immunology

Brief Research Report

Published on 26 Jun 2025

Efficacy and safety of ruxolitinib in adult patients with refractory rheumatic disease-associated macrophage activation syndrome

in Inflammation

Jingjing Li
Ran Wang
Jie Chen
Antao Xu
Yakai Fu
Yanwei Lin
Xiaodong Wang
Shuang Ye
Ye Yuan
Fang Du

Frontiers in Immunology

doi 10.3389/fimmu.2025.1604648

924 views

Review

Published on 26 Jun 2025

Liquid-liquid phase separation: an emerging perspective on the tumorigenesis, progression, and treatment of tumors

in Cancer Immunity and Immunotherapy

Qin Jian
Qi Xu
Sirui Xiang
Rongrong Wang
Chuchu Wang
Boxun Zhang
Ruli Li
Junzhi Lin
Chuan Zheng

Frontiers in Immunology

doi 10.3389/fimmu.2025.1604015

939 views

Review

Published on 26 Jun 2025

Gut microbiota-driven neuroinflammation in Alzheimer’s disease: from mechanisms to therapeutic opportunities

in Microbial Immunology

Wenhui Lei
Yiwen Cheng
Xia Liu
Jie Gao
Zhangcheng Zhu
Wenwen Ding
Xiaocui Xu
Yating Li
Zongxin Ling
Ruilai Jiang

Frontiers in Immunology

doi 10.3389/fimmu.2025.1582119

1,738 views

Original Research

Published on 26 Jun 2025

Integrative bioinformatics and machine learning approaches reveal oxidative stress and glucose metabolism related genes as therapeutic targets and drug candidates in Alzheimer’s disease

in Systems Immunology

Fatima Noor
Sidra Aslam
Ignazio S. Piras
Cecilia Tremblay
Thomas G. Beach
Geidy E. Serrano

Frontiers in Immunology

doi 10.3389/fimmu.2025.1572468

1,350 views

Systematic Review

Published on 26 Jun 2025

The prognostic and clinicopathological value of HALP score in non-small cell lung cancer

in Cancer Immunity and Immunotherapy

Qin Li
Mengqi Chen
Huaqin Zhao
Jiawei Zeng

Frontiers in Immunology

doi 10.3389/fimmu.2025.1576326

1,636 views

Original Research

Published on 26 Jun 2025

FTO O-GlcNAcylation promotes TRIM21-mediated FTO ubiquitination degradation to sustain the negative feedback control of macrophage inflammation

in Inflammation

Lu Zhang
Min Liu
Yan Xie
Bi-Feng Yuan
Zhiyong Peng
Jun Xiong
Xiao-Lian Zhang

Frontiers in Immunology

doi 10.3389/fimmu.2025.1593243

1,265 views

Original Research

Published on 26 Jun 2025

Essential cell-intrinsic requirement for GMDS in T cell development

in T Cell Biology

Mehmet Yabas
Carla M. Roots
T. Daniel Andrews
Matt A. Field
Christopher C. Goodnow
Anselm Enders

Frontiers in Immunology

doi 10.3389/fimmu.2025.1598923

846 views

Original Research

Published on 26 Jun 2025

Predicting immune-related adverse events in patients with melanoma: the role of interleukin-7 rs16906115 polymorphism and lymphocyte dynamics

in Cancer Immunity and Immunotherapy

Fatma Pınar Açar
Caner Acar
Damla Gunenc
Çağlar Arisoy
Asli Ece Solmaz
Asli Gecgel
Haydar Çağatay Yüksel
Gökhan Şahin
Oguzcan Ozkan
Zeynep Sila Gokdere

Frontiers in Immunology

doi 10.3389/fimmu.2025.1616325

1,062 views

Original Research

Published on 26 Jun 2025

Optimized multiplex PCR-NGS for comprehensive HLA genotyping in Chinese populations: resolving ambiguities at high resolution

in Alloimmunity and Transplantation

Cuello Garcia Haider
Binbin Sun
Yinfeng Wang
Zhoufan Zhang
Changling Cao
Yiying Zhu
Ouzaouit Abdelhak
Huiqiang Huang
Haitao Liu
Tingya Jiang

Frontiers in Immunology

doi 10.3389/fimmu.2025.1551173

1,028 views

Original Research

Published on 26 Jun 2025

Association between protein diet score and colorectal adenomas risk: a prospective study

in Nutritional Immunology

Yangpiaoyi Shi
Zhiquan Xu
Wanhao Tan
Hang Liu
Qi Wei
Yaxu Wang
Ling Xiang
Linglong Peng
Haitao Gu

Frontiers in Immunology

doi 10.3389/fimmu.2025.1529011

914 views

Original Research

Published on 26 Jun 2025

Multi-omics analysis reveals the role of ribosome biogenesis in malignant clear cell renal cell carcinoma and the development of a machine learning-based prognostic model

in Cancer Immunity and Immunotherapy

Zhouzhou Xie
Shansen Peng
Jiongming Wang
Yueting Huang
Xiaoqi Zhou
Guihao Zhang
Huiming Jiang
Kaihua Zhong
Lingsong Feng
Nanhui Chen

Frontiers in Immunology

doi 10.3389/fimmu.2025.1602898

1,411 views

Original Research

Published on 26 Jun 2025

Immunopathogenic and clinical implications of advanced tissue analysis in non-tuberculous mycobacterial infections in children

in Microbial Immunology

Maximilian Seidl
Elham Bavafaye Haghighi
Anne Kathrin Lösslein
Markus Hufnagel
Florens Lohrmann
Christian Schneider
Daniela S. Kohlfürst
Werner Zenz
Gregor Gorkiewicz
Cornelia Feiterna-Sperling

Frontiers in Immunology

doi 10.3389/fimmu.2025.1597074

666 views

Case Report

Published on 26 Jun 2025

Case Report: Can early full-course tocilizumab therapy reverse vascular stenosis in Takayasu arteritis?

in Autoimmune and Autoinflammatory Disorders : Autoimmune Disorders

Congqi Hu
Lingjie Liu
Hui Xiao
Hongjun Zhao
Guangxing Chen
Yanli Xie

Frontiers in Immunology

doi 10.3389/fimmu.2025.1593770

642 views

Original Research

Published on 26 Jun 2025

A consensus mathematical model of vaccine-induced antibody dynamics for multiple vaccine platforms and pathogens

in Vaccines and Molecular Therapeutics

Kristen M. Wilding
Carmen Molina-París
Jessica Z. Kubicek-Sutherland
Benjamin McMahon
Alan S. Perelson
Ruy M. Ribeiro

Frontiers in Immunology

doi 10.3389/fimmu.2025.1596518

961 views

Original Research

Published on 26 Jun 2025

Nanolipoprotein particle (NLP) vaccine confers protection against Yersinia pestis aerosol challenge in a BALB/c mouse model

in Vaccines and Molecular Therapeutics

Sergei S. Biryukov
Amy Rasley
Michael L. Davies
Christopher P. Klimko
Jennifer L. Dankmeyer
Melissa Hunter
Nathaniel O. Rill
Jennifer L. Shoe
Jeremy Miller
Yuli Talyansky

Frontiers in Immunology

doi 10.3389/fimmu.2025.1603710

1,311 views

Mini Review

Published on 26 Jun 2025

Extracellular vesicles: molecular messengers and new therapeutic targets in acute myocardial infarction

in Cytokines and Soluble Mediators in Immunity

Hao Wu
Jinyi Xue
Qiuyu Liu
Zhenxun Wan
Lingling Liang
Shihan Sun
Ping Liu
Mingtai Chen
Mengnan Liu

Frontiers in Immunology

doi 10.3389/fimmu.2025.1598407

987 views