Frontiers in Immunology | Autoimmune and Autoinflammatory Disorders : Autoimmune Disorders

Original Research

Published on 17 Feb 2026

Phosphoinositide 3-kinase δ activity in patients with systemic lupus erythematosus

in Autoimmune and Autoinflammatory Disorders : Autoimmune Disorders

Elham Sadat Mirfazeli
Shalmalee Kharkar
Michel W. P. Tsang-A-Sjoe
Olivier Papapietro
Izabella Niewczas
Agner R. Parra Sanchez
Anita Chandra
Klaus Okkenhaug
Irene E. M. Bultink
Reina E. Mebius

Frontiers in Immunology

doi 10.3389/fimmu.2026.1745692

301 views

Original Research

Published on 17 Feb 2026

Urinary extracellular vesicle metabolomic profiling reveals a distinct molecular signature for the non-invasive diagnosis of lupus nephritis

in Autoimmune and Autoinflammatory Disorders : Autoimmune Disorders

Nan Zhang
Ning Dong
Anran Xie
Wenjing Liu
Adeel Khan
Yanjing Rui
Ping Yang

Frontiers in Immunology

doi 10.3389/fimmu.2026.1741455

185 views

Original Research

Accepted on 16 Feb 2026

IFNγ-associated immune–metabolic remodeling is linked to serotonin–kynurenine imbalance and cortical vulnerability in lupus-prone mice

in Autoimmune and Autoinflammatory Disorders : Autoimmune Disorders

Karim Matmat
Rosa-Maria Guéant-Rodriguez
Emmanuel Darcq
Okan Baspinar
Jean-Marc Alberto
Jean-louis Gueant
Ayikoe Guy Mensah-Nyagan
Hélène Jeltsch-david

Frontiers in Immunology

Systematic Review

Accepted on 16 Feb 2026

The role of Interleukin-17 inhibition in systemic lupus erythematosus – paradoxical hindrance or new therapeutic potential? Results from a Systematic Literature Review and Mendelian Randomization

in Autoimmune and Autoinflammatory Disorders : Autoimmune Disorders

Deepak Nagra
Benajmin Zuckerman
Joy Odia
Samir Patel
Melissa Ong
Maryam Adas
Zijing Yang
Katie Bechman
Mark Russell
Sijan Bhandari

Frontiers in Immunology

Case Report

Accepted on 16 Feb 2026

Flagellate Eruption of Adult-onset Still disease in an Afro-Caribbean Woman: Highlighting Atypical Cutaneous Disease in Richly Pigmented Skin

in Autoimmune and Autoinflammatory Disorders : Autoimmune Disorders

Ceylon Gomes
Xaneile Facey
Danielle Morris
Jonathan D Ho

Frontiers in Immunology

Original Research

Accepted on 16 Feb 2026

Unveiling Biomarkers of Telitacicept's Efficacy in SLE Treatment Through Proteomics and Metabolomics

in Autoimmune and Autoinflammatory Disorders : Autoimmune Disorders

Huiyu Nie
Siyuan Chang
Hanhan Chen
Jiahui Shi
Shu Li
Xiaofei Peng
Wei Cheng
Jia Wang
Qi Tang
Yan Ge

Frontiers in Immunology

Review

Accepted on 16 Feb 2026

Microbial Transformation of Secondary Bile Acids: Roles in Gut Ecology and Autoimmune Diseases

in Autoimmune and Autoinflammatory Disorders : Autoimmune Disorders

Lulu Ren
Mengxin Li
Linping Wu
Zhiming Lin
Anping Chen

Frontiers in Immunology

Case Report

Accepted on 16 Feb 2026

Early-onset mevalonic aciduria in neonates with inflammatory marker elevated

in Autoimmune and Autoinflammatory Disorders : Autoimmune Disorders

Wujuan Shi
Xiaobo He
Shanshan Xue
Lihong Hao

Frontiers in Immunology

Review

Accepted on 16 Feb 2026

Advances in the study of low-density neutrophils in rheumatic diseases

in Autoimmune and Autoinflammatory Disorders : Autoimmune Disorders

Jiahua Yin
Qi Wang
Kaiyin Cai
Min Zhang
Xiaoyi Jia

Frontiers in Immunology

Case Report

Accepted on 16 Feb 2026

Tocilizumab in the Treatment of IgG4-Related Disease Involving the Carotid Artery-Case Report and Literature Review

in Autoimmune and Autoinflammatory Disorders : Autoimmune Disorders

Xiaoxu Ding
Juan Tao
Cheng Xu
Yongmei Han

Frontiers in Immunology

Case Report

Published on 16 Feb 2026

Recurrent anti-TIF1γ-positive dermatomyositis coexisting with postoperative parotid lymphoepithelial carcinoma: a case report with pathogenesis analysis

in Autoimmune and Autoinflammatory Disorders : Autoimmune Disorders

Xiaoguang Cui
Kaihong Ye
Hong Wang
Yali Kang
Junqiao Feng
Yameng Wei
Nan Xu
Fuqian Lei
Shan Wang
Rick F. Thorne

Frontiers in Immunology

doi 10.3389/fimmu.2026.1748650

173 views

Case Report

Published on 16 Feb 2026

Pulmonary light chain deposition disease secondary to Sjögren disease: a case report

in Autoimmune and Autoinflammatory Disorders : Autoimmune Disorders

Xiaotong Xu
Lingjian Wang
Chunsheng Zhou
Lu Zhang
Ting Zhang
Min Peng
Rui’e Feng
Juhong Shi

Frontiers in Immunology

doi 10.3389/fimmu.2026.1747455

176 views

Case Report

Published on 16 Feb 2026

Treatment of Kimura disease with dupilumab: a case report and literature review

in Autoimmune and Autoinflammatory Disorders : Autoimmune Disorders

Wei Yang
Ze Wu
Jun Niu

Frontiers in Immunology

doi 10.3389/fimmu.2026.1670489

156 views

Original Research

Accepted on 14 Feb 2026

Immune-related adverse events in patients with preexisting myasthenia gravis and thymoma following immune checkpoint inhibitor treatment: A retrospective, observational study

in Autoimmune and Autoinflammatory Disorders : Autoimmune Disorders

Chao Sun
Guo Rongjing
Xunliang Yin
Feng Lanlan
Yize Guo
Yueliang Xu
Sijia Hao
Xiaoxi Huang
Na Song
Ting Gao

Frontiers in Immunology

408 views

Original Research

Accepted on 14 Feb 2026

Racial Disparities in Ankylosing Spondylitis Risk Following Tonsillectomy: A Large-Scale Retrospective Analysis

in Autoimmune and Autoinflammatory Disorders : Autoimmune Disorders

Jiafeng Zhang
Yadong Chu
Yufeng Zhu
Huang Hua Bing
Chien Han Tsao
Yu Hsun Wang
Jame Cheng-Chun Wei

Frontiers in Immunology

324 views

Editorial

Accepted on 13 Feb 2026

Editorial: Novel Biomarkers for Early Diagnosis, involved in Autoimmune and Autoinflammatory Diseases

in Autoimmune and Autoinflammatory Disorders : Autoimmune Disorders

Jan Stępniak
Katarzyna Wojciechowska-Durczyńska
Małgorzata Karbownik-Lewińska

Frontiers in Immunology

Review

Accepted on 13 Feb 2026

The PANoptotic Mosaic of Rheumatoid Arthritis: Epitranscriptomic Regulation, Systemic Relays, and Precision Death-Mode Editing

in Autoimmune and Autoinflammatory Disorders : Autoimmune Disorders

Shu Li
Lei Wan
Xiaojun Zhang

Frontiers in Immunology

Original Research

Published on 13 Feb 2026

Transcriptomic profiling reveals distinct molecular signatures among lesion types in hidradenitis suppurativa

in Autoimmune and Autoinflammatory Disorders : Autoimmune Disorders

Hakim Ben Abdallah
Christine Daugaard
Louise Schøsler
Mads Kirchheiner Rasmussen
Line Kibsgaard
Trine Høgsberg
Claus Johansen
Trine Bertelsen

Frontiers in Immunology

doi 10.3389/fimmu.2025.1715474

484 views

Original Research

Published on 13 Feb 2026

Thromboembolic adverse events associated with TPO-RA in ITP treatment: a pharmacovigilance analysis of the FDA Adverse Event Reporting System

in Autoimmune and Autoinflammatory Disorders : Autoimmune Disorders

Zhen Lu
Yingjian Zeng
Guangbin Shang
Xiaonan Lu

Frontiers in Immunology

doi 10.3389/fimmu.2026.1669486

329 views

Original Research

Published on 13 Feb 2026

A novel murine model of Sjögren’s disease using lacrimal autoantigen

in Autoimmune and Autoinflammatory Disorders : Autoimmune Disorders

Siyuan Li
Shan Liu
Yaqiong Li
Peng Zhang
Fengyang Lei
Lei Tian
Ying Jie

Frontiers in Immunology

doi 10.3389/fimmu.2026.1586519

344 views

Correction

Published on 13 Feb 2026

Correction: TRIM21 regulation of IRF-mediated type I interferon signaling in systemic autoimmune diseases

in Autoimmune and Autoinflammatory Disorders : Autoimmune Disorders

Kailai Panlu
Yihan Wang
Xinchao Zhu
Zhiting Lin
Ting Fang
Xinyi Yao
Zhimin Xie
Xinchang Wang

Frontiers in Immunology

doi 10.3389/fimmu.2026.1804355

200 views

Case Report

Accepted on 12 Feb 2026

Eosinophilic Granulomatosis with Polyangiitis Coexisting with Multiple Myeloma: Independent Entities or Coexistence? A Case Report

in Autoimmune and Autoinflammatory Disorders : Autoimmune Disorders

Longyan Qin
Yi Yin
Pengjia Wu
Aifei Zhang
Na li
Jun Liu
Ling Huang
Jun Cao
Jiashun Zeng

Frontiers in Immunology

151 views

Review

Accepted on 12 Feb 2026

Mapping the Immune Landscape of Systemic Sclerosis: From Cellular Crosstalk to Precision Therapeutic Strategies The Immune Landscape of Systemic Sclerosis: From Pathogenic Mechanisms to Precision Therapeutic Breakthroughs

in Autoimmune and Autoinflammatory Disorders : Autoimmune Disorders

Mengguo Liu

Frontiers in Immunology

Review

Accepted on 12 Feb 2026

Organoid–Microglia System for Modeling the Immune Microenvironment of the Brain and Retina

in Autoimmune and Autoinflammatory Disorders : Autoimmune Disorders

Jingjing Yu
Binxin Tang
Zhanjing Gu
Guanyuan Wang
Aijing Liu

Frontiers in Immunology

2,193 articles

articles

Phosphoinositide 3-kinase δ activity in patients with systemic lupus erythematosus

Urinary extracellular vesicle metabolomic profiling reveals a distinct molecular signature for the non-invasive diagnosis of lupus nephritis

IFNγ-associated immune–metabolic remodeling is linked to serotonin–kynurenine imbalance and cortical vulnerability in lupus-prone mice

The role of Interleukin-17 inhibition in systemic lupus erythematosus – paradoxical hindrance or new therapeutic potential? Results from a Systematic Literature Review and Mendelian Randomization

Flagellate Eruption of Adult-onset Still disease in an Afro-Caribbean Woman: Highlighting Atypical Cutaneous Disease in Richly Pigmented Skin

Unveiling Biomarkers of Telitacicept's Efficacy in SLE Treatment Through Proteomics and Metabolomics

Microbial Transformation of Secondary Bile Acids: Roles in Gut Ecology and Autoimmune Diseases

Early-onset mevalonic aciduria in neonates with inflammatory marker elevated

Advances in the study of low-density neutrophils in rheumatic diseases

Tocilizumab in the Treatment of IgG4-Related Disease Involving the Carotid Artery-Case Report and Literature Review

Recurrent anti-TIF1γ-positive dermatomyositis coexisting with postoperative parotid lymphoepithelial carcinoma: a case report with pathogenesis analysis

Pulmonary light chain deposition disease secondary to Sjögren disease: a case report

Treatment of Kimura disease with dupilumab: a case report and literature review

Immune-related adverse events in patients with preexisting myasthenia gravis and thymoma following immune checkpoint inhibitor treatment: A retrospective, observational study

Racial Disparities in Ankylosing Spondylitis Risk Following Tonsillectomy: A Large-Scale Retrospective Analysis

Editorial: Novel Biomarkers for Early Diagnosis, involved in Autoimmune and Autoinflammatory Diseases

The PANoptotic Mosaic of Rheumatoid Arthritis: Epitranscriptomic Regulation, Systemic Relays, and Precision Death-Mode Editing

Transcriptomic profiling reveals distinct molecular signatures among lesion types in hidradenitis suppurativa

Thromboembolic adverse events associated with TPO-RA in ITP treatment: a pharmacovigilance analysis of the FDA Adverse Event Reporting System

A novel murine model of Sjögren’s disease using lacrimal autoantigen

Correction: TRIM21 regulation of IRF-mediated type I interferon signaling in systemic autoimmune diseases

Eosinophilic Granulomatosis with Polyangiitis Coexisting with Multiple Myeloma: Independent Entities or Coexistence? A Case Report

Mapping the Immune Landscape of Systemic Sclerosis: From Cellular Crosstalk to Precision Therapeutic Strategies The Immune Landscape of Systemic Sclerosis: From Pathogenic Mechanisms to Precision Therapeutic Breakthroughs

Organoid–Microglia System for Modeling the Immune Microenvironment of the Brain and Retina