Frontiers in Immunology | Autoimmune and Autoinflammatory Disorders: Autoinflammatory Disorders

Original Research

Published on 13 Feb 2026

Bitter gourd peptides (BG) alleviate lupus progression in mice through regulation of miR-146a/BRD4 axis in macrophages

in Autoimmune and Autoinflammatory Disorders: Autoinflammatory Disorders

Yu Wu
Wenyan Han
Xian Li
Xiulan Su

Frontiers in Immunology

doi 10.3389/fimmu.2026.1666212

474 views

Review

Accepted on 12 Feb 2026

Towards a basis for Vascular versus Intestinal Phenotype Differences; East Meets West in Behcet’s Disease

in Autoimmune and Autoinflammatory Disorders: Autoinflammatory Disorders

Kerem Abacar
Tom Macleod
FATMA ALIBAZ-ONER
Haner Direskeneli
Dennis McGonagle

Frontiers in Immunology

Review

Accepted on 10 Feb 2026

The SIRP Family: From Structural Diversity and Signaling Mechanisms to Implications in Immune-related Disease Targeted Therapeutics

in Autoimmune and Autoinflammatory Disorders: Autoinflammatory Disorders

Yanmei Jin
Qiu-Yang Huang
Jiaqi Song
Zain ul Abideen
Ruijiong Tan
Shaohua Xu
Ming Chen

Frontiers in Immunology

Case Report

Accepted on 10 Feb 2026

Case Report: Endothelial-Targeted Bridging Therapy for a TTP-Like Phenotype in Fulminant iMCD-TAFRO

in Autoimmune and Autoinflammatory Disorders: Autoinflammatory Disorders

Jing Du
Liangliang Wu
Haigang Li
Haibo Gan
Tao Yu
Shuangfeng Xie
Xiangshao Fang

Frontiers in Immunology

Brief Research Report

Published on 10 Feb 2026

Absolute quantification of microRNA miR-875-5p in temporal artery biopsies and its biomarker potential for giant cell arteritis

in Autoimmune and Autoinflammatory Disorders: Autoinflammatory Disorders

Luka Bolha
Elvisa Smajlović
Alojzija Hočevar

Frontiers in Immunology

doi 10.3389/fimmu.2026.1676244

460 views

Review

Published on 10 Feb 2026

Metabolic checkpoints in the regulation of Th17 cells: implications for uveitis pathogenesis and therapy

in Autoimmune and Autoinflammatory Disorders: Autoinflammatory Disorders

YongFei Ma
QiuJin Zhang
ZhiXiang Ding

Frontiers in Immunology

doi 10.3389/fimmu.2026.1690141

155 views

Correction

Accepted on 09 Feb 2026

Correction: VEXAS: A review of current understandings and emerging treatment strategies

in Autoimmune and Autoinflammatory Disorders: Autoinflammatory Disorders

Robert Holden
Yogeshraj Jeelall
Andrew McLean-Tooke
Kylan Pathmanathan
David Nolan

Frontiers in Immunology

Original Research

Published on 09 Feb 2026

Long-term follow-up of linear scleroderma en coup de sabre in children with central nervous system involvement

in Autoimmune and Autoinflammatory Disorders: Autoinflammatory Disorders

Xingzhi Chang
Lihong Ren
Ye Wu
Yuehua Zhang
Cuijie Wei
Qingping Zhang
Meijiao Zhang
Chunyan Zhao
Xinhua Bao

Frontiers in Immunology

doi 10.3389/fimmu.2026.1740848

421 views

Original Research

Published on 06 Feb 2026

Lupus nephritis and its association with subclinical myocardial alterations in systemic lupus erythematosus assessed by cardiovascular magnetic resonance

in Autoimmune and Autoinflammatory Disorders: Autoinflammatory Disorders

Zhi Yang
Ling-li Wang
Tian-yue Zhang
Miao Wen
Hao Zou
Yong Zhu
Xue Meng
Liang-chao Gao
Bing Fu
Shu-yue Pan

Frontiers in Immunology

doi 10.3389/fimmu.2026.1749478

239 views

Review

Accepted on 05 Feb 2026

Trichuris suis Ova in Inflammatory Bowel Disease

in Autoimmune and Autoinflammatory Disorders: Autoinflammatory Disorders

Su Zhou
Jiong Tang
Yu Wang

Frontiers in Immunology

216 views

Original Research

Accepted on 05 Feb 2026

Multi-dimensional Evidence Establishing the Causal Association Between Metabolic Syndrome and Gout and the Molecular Mechanisms of Comorbidity

in Autoimmune and Autoinflammatory Disorders: Autoinflammatory Disorders

Jianbin Li
Jiamin Zhang
Suiran Li
晓戈姚
Renhe Li
Wei Liu

Frontiers in Immunology

Review

Published on 05 Feb 2026

Ferroptosis in gouty arthritis: a potential therapeutic strategy

in Autoimmune and Autoinflammatory Disorders: Autoinflammatory Disorders

Heguo Yan
Niqin Xiao
Bo Yang
Jian Zhang
Yundong Xu
Bingbing Chen
Sanjin Zeng
He Qian
Shengyi Zhao
Rong Wang

Frontiers in Immunology

doi 10.3389/fimmu.2026.1769719

473 views

Review

Published on 05 Feb 2026

Beyond inhaled medications: precision medicine and biologic therapies targeting the IL-33/TSLP/type 2 axis in COPD

in Autoimmune and Autoinflammatory Disorders: Autoinflammatory Disorders

Guo-qiang Song
Bangsheng Chen
Tian-li He
Guo-qiang Hu

Frontiers in Immunology

doi 10.3389/fimmu.2026.1772031

776 views

Original Research

Published on 05 Feb 2026

Therapeutic drug monitoring of adalimumab in hidradenitis suppurativa: a prospective observational study

in Autoimmune and Autoinflammatory Disorders: Autoinflammatory Disorders

Stella X. Chen
Bruna Galvao de O. Wafae
Sydney Look-Why
Tracey Otto
Corey Snyder
William Sweet
Nazrin Ashina
Ruby Gibson
Prerna Salian
Maneli Doroudian Tehrani

Frontiers in Immunology

doi 10.3389/fimmu.2026.1760206

699 views

Original Research

Published on 05 Feb 2026

Tocilizumab combined with short-term high-dose glucocorticoids for rapid disease activity control and glucocorticoid reduction in adult-onset Still’s disease: a single-center retrospective study

in Autoimmune and Autoinflammatory Disorders: Autoinflammatory Disorders

Shi-Lei Zhong
Yan-Ping Lei
Li-Xuan Zhou
Ai-Xia Niu
Bo Liu
Yong-Long He
Qi-Bin Yang

Frontiers in Immunology

doi 10.3389/fimmu.2026.1732826

472 views

Case Report

Published on 05 Feb 2026

Case Report: Upadacitinib for SAPHO syndrome with biologics-induced paradoxical manifestation and Hyperimmunoglobulinemia E

in Autoimmune and Autoinflammatory Disorders: Autoinflammatory Disorders

Yuxi Liu
Di Jin
Wen Li
Shiqi Zhang
Chen Li
Xin Li

Frontiers in Immunology

doi 10.3389/fimmu.2026.1728245

696 views

Original Research

Accepted on 04 Feb 2026

Clinical, immunological characterisation and treatment response of patients with syndrome of undifferentiated recurrent fever (SURF) in Chinese children and adolescents: a single-centre cohort study

in Autoimmune and Autoinflammatory Disorders: Autoinflammatory Disorders

Chen Xiongbin
Xing Wenlu
Li Yulu
Yang Mengyang
Zhou Shu
Mao Huawei

Frontiers in Immunology

Case Report

Accepted on 03 Feb 2026

Diverse Pediatric Phenotypes of RELA Frameshift Variants: Comparison of Two Cases

in Autoimmune and Autoinflammatory Disorders: Autoinflammatory Disorders

Ling Hou
Lu Yin
Chengguang Zhao
Yue Du

Frontiers in Immunology

230 views

Review

Accepted on 03 Feb 2026

Ferroptosis as a Therapeutic Nexus: Traditional Chinese Medicine Interventions in Rheumatoid Arthritis

in Autoimmune and Autoinflammatory Disorders: Autoinflammatory Disorders

Ruibin Yang
Ziwei Yang
Zhuan Feng
Yaxin Ding
Jiali Yang
Yinuo Zhang
Zhinan Chen
Fei Huo
Jiao Wu

Frontiers in Immunology

249 views

Original Research

Accepted on 03 Feb 2026

The evaluation of the plasma levels of interleukin 17A, thymic stromal lymphopoietin, interferon gamma, tumor necrosis factor-alpha and interleukins IL-2, IL-6, IL-23, and IL-31 in atopic dermatitis patients with dupilumab treatment

in Autoimmune and Autoinflammatory Disorders: Autoinflammatory Disorders

Jarmila Celakovska
Eva Cermakova
Petra Boudková
Ctirad Andrys

Frontiers in Immunology

Case Report

Published on 03 Feb 2026

A fatal course of hemophagocytic lymphohistiocytosis in a child with homozygous ERCC6L2 defect and heterozygous ADA2 variant: a case report

in Autoimmune and Autoinflammatory Disorders: Autoinflammatory Disorders

Szymon Lulek
Katarzyna Bąbol-Pokora
Monika Radwańska
Daniel Popiel
Magdalena Reich
Wojciech Młynarski
Radosław Chaber

Frontiers in Immunology

doi 10.3389/fimmu.2025.1717567

592 views

Original Research

Accepted on 02 Feb 2026

Multi-omics analysis reveals the mechanism of verbenalin in treating gout via modulating purine metabolism, gut microbiota, and inflammatory pathways

in Autoimmune and Autoinflammatory Disorders: Autoinflammatory Disorders

Yan Xiao
Ting Zhang
Qianglong Chen
Yiqian Zhang
Bingyan Chen
Meiling Wang
Yingjie Zhang
Mingqing Huang
Jiemei Guo
Youxin Su

Frontiers in Immunology

Review

Accepted on 30 Jan 2026

Immunometabolism in Rheumatoid Arthritis: Mechanisms, Biomarkers, and the Path to Precision Medicine

in Autoimmune and Autoinflammatory Disorders: Autoinflammatory Disorders

Xinyu Liu
Jiajia Wang
Tong Lou
Qiaomu Tang
Zixin Fang
Wenfeng Zhang
Yinghua Hu

Frontiers in Immunology

426 views

Original Research

Accepted on 30 Jan 2026

Amelioration of Psoriasis-Like Skin Lesions by Human Amniotic Mesenchymal Stem Cells: Insights from Multiomics Profiling in Mice

in Autoimmune and Autoinflammatory Disorders: Autoinflammatory Disorders

Liehao Yang
Baihui Miao
Qian Sun
Fangqing Zhang
Hongyan Sun
Zilong Zhou
Yue Hu
Zhiming Cui
Dongxu Wang
Chenlu Liu

Frontiers in Immunology

148 views

546 articles

articles

Bitter gourd peptides (BG) alleviate lupus progression in mice through regulation of miR-146a/BRD4 axis in macrophages

Towards a basis for Vascular versus Intestinal Phenotype Differences; East Meets West in Behcet’s Disease

The SIRP Family: From Structural Diversity and Signaling Mechanisms to Implications in Immune-related Disease Targeted Therapeutics

Case Report: Endothelial-Targeted Bridging Therapy for a TTP-Like Phenotype in Fulminant iMCD-TAFRO

Absolute quantification of microRNA miR-875-5p in temporal artery biopsies and its biomarker potential for giant cell arteritis

Metabolic checkpoints in the regulation of Th17 cells: implications for uveitis pathogenesis and therapy

Correction: VEXAS: A review of current understandings and emerging treatment strategies

Long-term follow-up of linear scleroderma en coup de sabre in children with central nervous system involvement

Lupus nephritis and its association with subclinical myocardial alterations in systemic lupus erythematosus assessed by cardiovascular magnetic resonance

Trichuris suis Ova in Inflammatory Bowel Disease

Multi-dimensional Evidence Establishing the Causal Association Between Metabolic Syndrome and Gout and the Molecular Mechanisms of Comorbidity

Ferroptosis in gouty arthritis: a potential therapeutic strategy

Beyond inhaled medications: precision medicine and biologic therapies targeting the IL-33/TSLP/type 2 axis in COPD

Therapeutic drug monitoring of adalimumab in hidradenitis suppurativa: a prospective observational study

Tocilizumab combined with short-term high-dose glucocorticoids for rapid disease activity control and glucocorticoid reduction in adult-onset Still’s disease: a single-center retrospective study

Case Report: Upadacitinib for SAPHO syndrome with biologics-induced paradoxical manifestation and Hyperimmunoglobulinemia E

Clinical, immunological characterisation and treatment response of patients with syndrome of undifferentiated recurrent fever (SURF) in Chinese children and adolescents: a single-centre cohort study

Diverse Pediatric Phenotypes of RELA Frameshift Variants: Comparison of Two Cases

Ferroptosis as a Therapeutic Nexus: Traditional Chinese Medicine Interventions in Rheumatoid Arthritis

The evaluation of the plasma levels of interleukin 17A, thymic stromal lymphopoietin, interferon gamma, tumor necrosis factor-alpha and interleukins IL-2, IL-6, IL-23, and IL-31 in atopic dermatitis patients with dupilumab treatment

A fatal course of hemophagocytic lymphohistiocytosis in a child with homozygous ERCC6L2 defect and heterozygous ADA2 variant: a case report

Multi-omics analysis reveals the mechanism of verbenalin in treating gout via modulating purine metabolism, gut microbiota, and inflammatory pathways

Immunometabolism in Rheumatoid Arthritis: Mechanisms, Biomarkers, and the Path to Precision Medicine

Amelioration of Psoriasis-Like Skin Lesions by Human Amniotic Mesenchymal Stem Cells: Insights from Multiomics Profiling in Mice