Frontiers in Immunology | Autoimmune and Autoinflammatory Disorders: Autoinflammatory Disorders

Brief Research Report

Published on 04 Dec 2025

A data-driven model of macrophage polarization states reveals an IFN macrophage signature in active Crohn’s disease

in Autoimmune and Autoinflammatory Disorders: Autoinflammatory Disorders

Sarina C. Lowe
Madelaine Leitman
Noah Yan
Alexander Hoffmann

Frontiers in Immunology

doi 10.3389/fimmu.2025.1707719

253 views

Mini Review

Published on 03 Dec 2025

Beyond the joints: mechanistic insights and multidisciplinary strategies for spondyloarthritis-associated uveitis

in Autoimmune and Autoinflammatory Disorders: Autoinflammatory Disorders

Shuyue Pan
Ling Xiang
Zhi Cao
Zhi Yang
Rui-Juan Cheng

Frontiers in Immunology

doi 10.3389/fimmu.2025.1715107

181 views

Brief Research Report

Published on 02 Dec 2025

VEXAS syndrome in rheumatology practice: features from a multicenter cohort in north-east Italy

in Autoimmune and Autoinflammatory Disorders: Autoinflammatory Disorders

Sara Bindoli
Greta Morello-Pasin
Irina Guidea
Roberto Padoan
Luca Iorio
Riccardo Bixio
Giovanni Orsolini
Federica Maiolini
Sara Lombardi
Sandra Lombardi

Frontiers in Immunology

doi 10.3389/fimmu.2025.1700737

313 views

Original Research

Published on 02 Dec 2025

Serum and urine anti-PLA2R antibody correlation with albuminuria in idiopathic membranous nephropathy

in Autoimmune and Autoinflammatory Disorders: Autoinflammatory Disorders

Xiaogang Liu
Yunfei Fu
Manshu Sui
Xuehua Wang
Zizhen Li

Frontiers in Immunology

doi 10.3389/fimmu.2025.1670960

223 views

Review

Accepted on 30 Nov 2025

Pyroptosis-Driven Immune Dysregulation in COPD: Molecular Mechanisms and Therapeutic Implications

in Autoimmune and Autoinflammatory Disorders: Autoinflammatory Disorders

Feng-Xian Ni
Hua-Jing Huang
Pei-Sheng Chen
Huihui Chen
Dong-Hui Huang
Zebo Jiang

Frontiers in Immunology

Case Report

Accepted on 28 Nov 2025

IgG4-Related Disease Presenting with Hypercalcemia: Case Report and Mechanistic Insights

in Autoimmune and Autoinflammatory Disorders: Autoinflammatory Disorders

Yaxin Li
Xing Niu
Ling Li
Zhangxue Hu

Frontiers in Immunology

110 views

Case Report

Published on 28 Nov 2025

Case Report: VEXAS syndrome with extensive pulmonary, cardiac, and skeletal involvement

in Autoimmune and Autoinflammatory Disorders: Autoinflammatory Disorders

Zhongbiao Fang
Tingwei Xu
Meng Zhang
Chaonan Li
Anwen Zheng
Yudan Gu
Chuhan Lan
Zongming Liu
Lingling Tang

Frontiers in Immunology

doi 10.3389/fimmu.2025.1724045

357 views

Editorial

Accepted on 27 Nov 2025

Editorial: Exploring Immune-Stromal Cell Dynamics: Pathways and Therapeutic Implications

in Autoimmune and Autoinflammatory Disorders: Autoinflammatory Disorders

Stacy Ryu
Stephen Gauld
Matthew Staron
Timothy Radstake
Ian Odell
Jenna L Cash

Frontiers in Immunology

210 views

Review

Accepted on 27 Nov 2025

Research progress on the application of nanobodies in immunity and infectious skin diseases

in Autoimmune and Autoinflammatory Disorders: Autoinflammatory Disorders

Liguo Qiu
Fengming Hu
Xiaohua Tao

Frontiers in Immunology

Original Research

Published on 27 Nov 2025

Single-cell transcriptomic analysis reveals a systemic immune dysregulation in intravenous immunoglobulin non-responsive Kawasaki disease

in Autoimmune and Autoinflammatory Disorders: Autoinflammatory Disorders

Chenhui Feng
Qirui Li
Minna Yang
Yeshi Chen
Mingming Zhang
Hongmao Wang
Xiaohui Li

Frontiers in Immunology

doi 10.3389/fimmu.2025.1702290

381 views

Original Research

Accepted on 26 Nov 2025

Therapeutic Drug Monitoring Plays an Important Role in Patients with Noninfectious Uveitis Receiving Adalimumab

in Autoimmune and Autoinflammatory Disorders: Autoinflammatory Disorders

Weidong Cheng
Jiayu Xiao
Shengjie Li
Huaru Wang
Shasha Wang
Yujing Qian
Chan Zhao
Fei Gao
XUZHEN QIN
Meifen Zhang

Frontiers in Immunology

Original Research

Published on 26 Nov 2025

A machine learning algorithm to predict treatment effectiveness for Kawasaki disease in China: a retrospective model development and validation study

in Autoimmune and Autoinflammatory Disorders: Autoinflammatory Disorders

Xuemei Li
Zihan Zhou
Jingyi Fan
Lin Zhao
Ruidi Xu
Dong Li
Xu Ma
Lu Sun
Yujian Wu
Zhouping Wang

Frontiers in Immunology

doi 10.3389/fimmu.2025.1629600

393 views

Review

Accepted on 25 Nov 2025

Co-occurrence of autoimmune diseases and metabolic disorders in Familial Mediterranean Fever (FMF) patients: review of literature and case reports

in Autoimmune and Autoinflammatory Disorders: Autoinflammatory Disorders

Ahlam Chaaban
Nohad Baalbaki
Ralph Narch
Eliana Eldawra
Philippe Hussein Kobeissy
José-Noel Ibrahim

Frontiers in Immunology

201 views

Review

Published on 25 Nov 2025

Citrullinated peptides as drug candidates for rheumatoid arthritis

in Autoimmune and Autoinflammatory Disorders: Autoinflammatory Disorders

Adrian H. Bustos
Mads Brüner
Tue Wenzel Kragstrup
Kira Astakhova

Frontiers in Immunology

doi 10.3389/fimmu.2025.1648913

747 views

Perspective

Accepted on 24 Nov 2025

Cross-talk Between Aging Resilience Pathways and Autoimmunity Onset

in Autoimmune and Autoinflammatory Disorders: Autoinflammatory Disorders

Rahul Mittal
Danay Saavedra
Mannat Mittal
Khemraj Hirani

Frontiers in Immunology

Original Research

Accepted on 24 Nov 2025

A Comparative Study of Large-Vessel and Small-Vessel Primary Angiitis of the Central Nervous System (PACNS): Insights from a Chinese Single-Center Retrospective Cohort

in Autoimmune and Autoinflammatory Disorders: Autoinflammatory Disorders

Yifan Wang
Jiangyi Lu
Fangfang Li
Jing Zhao
Yu He
Shangtian Xiang
Weizhou Zang

Frontiers in Immunology