Frontiers in Immunology | Autoimmune and Autoinflammatory Disorders: Autoinflammatory Disorders

Case Report

Published on 05 Feb 2026

Case Report: Upadacitinib for SAPHO syndrome with biologics-induced paradoxical manifestation and Hyperimmunoglobulinemia E

in Autoimmune and Autoinflammatory Disorders: Autoinflammatory Disorders

Yuxi Liu
Di Jin
Wen Li
Shiqi Zhang
Chen Li
Xin Li

Frontiers in Immunology

doi 10.3389/fimmu.2026.1728245

786 views

Original Research

Accepted on 04 Feb 2026

Clinical, immunological characterisation and treatment response of patients with syndrome of undifferentiated recurrent fever (SURF) in Chinese children and adolescents: a single-centre cohort study

in Autoimmune and Autoinflammatory Disorders: Autoinflammatory Disorders

Chen Xiongbin
Xing Wenlu
Li Yulu
Yang Mengyang
Zhou Shu
Mao Huawei

Frontiers in Immunology

Case Report

Accepted on 03 Feb 2026

Diverse Pediatric Phenotypes of RELA Frameshift Variants: Comparison of Two Cases

in Autoimmune and Autoinflammatory Disorders: Autoinflammatory Disorders

Ling Hou
Lu Yin
Chengguang Zhao
Yue Du

Frontiers in Immunology

245 views

Review

Accepted on 03 Feb 2026

Ferroptosis as a Therapeutic Nexus: Traditional Chinese Medicine Interventions in Rheumatoid Arthritis

in Autoimmune and Autoinflammatory Disorders: Autoinflammatory Disorders

Ruibin Yang
Ziwei Yang
Zhuan Feng
Yaxin Ding
Jiali Yang
Yinuo Zhang
Zhinan Chen
Fei Huo
Jiao Wu

Frontiers in Immunology

262 views

Original Research

Accepted on 03 Feb 2026

The evaluation of the plasma levels of interleukin 17A, thymic stromal lymphopoietin, interferon gamma, tumor necrosis factor-alpha and interleukins IL-2, IL-6, IL-23, and IL-31 in atopic dermatitis patients with dupilumab treatment

in Autoimmune and Autoinflammatory Disorders: Autoinflammatory Disorders

Jarmila Celakovska
Eva Cermakova
Petra Boudková
Ctirad Andrys

Frontiers in Immunology

104 views

Case Report

Published on 03 Feb 2026

A fatal course of hemophagocytic lymphohistiocytosis in a child with homozygous ERCC6L2 defect and heterozygous ADA2 variant: a case report

in Autoimmune and Autoinflammatory Disorders: Autoinflammatory Disorders

Szymon Lulek
Katarzyna Bąbol-Pokora
Monika Radwańska
Daniel Popiel
Magdalena Reich
Wojciech Młynarski
Radosław Chaber

Frontiers in Immunology

doi 10.3389/fimmu.2025.1717567

652 views

Original Research

Accepted on 02 Feb 2026

Multi-omics analysis reveals the mechanism of verbenalin in treating gout via modulating purine metabolism, gut microbiota, and inflammatory pathways

in Autoimmune and Autoinflammatory Disorders: Autoinflammatory Disorders

Yan Xiao
Ting Zhang
Qianglong Chen
Yiqian Zhang
Bingyan Chen
Meiling Wang
Yingjie Zhang
Mingqing Huang
Jiemei Guo
Youxin Su

Frontiers in Immunology

106 views

Review

Accepted on 30 Jan 2026

Immunometabolism in Rheumatoid Arthritis: Mechanisms, Biomarkers, and the Path to Precision Medicine

in Autoimmune and Autoinflammatory Disorders: Autoinflammatory Disorders

Xinyu Liu
Jiajia Wang
Tong Lou
Qiaomu Tang
Zixin Fang
Wenfeng Zhang
Yinghua Hu

Frontiers in Immunology

444 views

Review

Published on 29 Jan 2026

Immune cell dynamics and mechanisms of epithelial injury in celiac disease

in Autoimmune and Autoinflammatory Disorders: Autoinflammatory Disorders

Irene Marafini
Silvia Salvatori
Edoardo Troncone
Pasquale De Vico
Elena De Cristofaro
Giovanni Monteleone

Frontiers in Immunology

doi 10.3389/fimmu.2026.1766513

758 views

Original Research

Published on 27 Jan 2026

A 76-week real-world multidimensional analysis of guselkumab in moderate to severe plaque psoriasis: a retrospective cohort study based on Chinese clinical practice standards

in Autoimmune and Autoinflammatory Disorders: Autoinflammatory Disorders

Runlu Hu
Qian Li
Xinli Liu
Yulian Hu
Yun Pan
Chuan Liu
Peilin Lu
Xiaoli Chen
Jianxia Xiong
Jingbo Zhang

Frontiers in Immunology

doi 10.3389/fimmu.2026.1684996

769 views

Review

Published on 27 Jan 2026

Deciphering the immunocellular regulatory network in inflammatory bowel disease: from susceptibility genes to cellular effectors and toward precision therapies

in Autoimmune and Autoinflammatory Disorders: Autoinflammatory Disorders

Zhuzhu Wu
Xiaolin Wang
Zitong Guan
Mengxue Han
Wenke Ma
Jie Li
Shuai Man
Zhenguo Wang
Qibiao Wu

Frontiers in Immunology

doi 10.3389/fimmu.2025.1719366

800 views

Review

Published on 21 Jan 2026

Advances in the pathogenesis of rosacea

in Autoimmune and Autoinflammatory Disorders: Autoinflammatory Disorders

Hui Wang
Cheng Zhou

Frontiers in Immunology

doi 10.3389/fimmu.2025.1705588

1,342 views

Original Research

Published on 21 Jan 2026

Hashimoto’s thyroiditis is associated with reduced invasiveness in papillary thyroid carcinoma: a propensity score-matched retrospective cohort study

in Autoimmune and Autoinflammatory Disorders: Autoinflammatory Disorders

Rui Li
Xu Sun
Liai Hu
Zhiyuan Yu
Na Liu
Peiyu Li
Xudong Zhao
Wenquan Liang

Frontiers in Immunology

doi 10.3389/fimmu.2025.1745452

782 views

Case Report

Published on 21 Jan 2026

Case Report: Diagnostic challenges in VEXAS syndrome with novel ultrastructural lung findings: IgG4-RD and vasculitis as relevant differential diagnoses

in Autoimmune and Autoinflammatory Disorders: Autoinflammatory Disorders

Peter Etzel
David Lang
Gregor Öberseder
Bernd Lamprecht

Frontiers in Immunology

doi 10.3389/fimmu.2025.1742328

792 views

Original Research

Published on 16 Jan 2026

Impact of treatment interruption on the efficacy and safety of vunakizumab in patients with moderate-to-severe plaque psoriasis: a post-hoc analysis of a phase 3 trial

in Autoimmune and Autoinflammatory Disorders: Autoinflammatory Disorders

Qunyan Li
Weifeng Yao
Dongyun Lei
Yan Xu
Litao Zhang
Zuotao Zhao
Junchen He
Tao Guo
Junying Li

Frontiers in Immunology

doi 10.3389/fimmu.2025.1639049

1,059 views

Case Report

Published on 14 Jan 2026

Exploring targeted therapy in retinal vasculopathy with cerebral leukoencephalopathy: a case report and review of literature

in Autoimmune and Autoinflammatory Disorders: Autoinflammatory Disorders

Patricia Tato-Moreno
Cristina Lavilla Olleros
Héctor Balastegui Martín
María Barrientos Guerrero
Anna Mensa-Vilaro
María Esther Durán-García
Paloma Sánchez-Mateos
Elena García-Martínez

Frontiers in Immunology

doi 10.3389/fimmu.2025.1707532

1,198 views

Original Research

Published on 14 Jan 2026

Targeted degradation of MK2 is insufficient to block inflammatory cytokine production in human cells due to cooperativity with MK3 and MK5

in Autoimmune and Autoinflammatory Disorders: Autoinflammatory Disorders

Bin Yang
Guoqiang Fang
Isaac Marx
Guang Liu
Stephanie Skouras
Kirti Sharma
Dirk M. Walther
Sarah Bollinger Martinez
Cedric Hubeau
Yatao Shi

Frontiers in Immunology

doi 10.3389/fimmu.2025.1712589

1,008 views

Original Research

Published on 12 Jan 2026

A multi-omics analysis of pancreatitis: bridging familial genetics and disease progression

in Autoimmune and Autoinflammatory Disorders: Autoinflammatory Disorders

Fu Li
Jin-xin Huang
Wen-jie Sun
Jing-qing Zeng
Ke-xin Gan
Biao Gong
Jian-mei Ji
Jian Chen
Zhao-hui Deng
Dong-liang Xu

Frontiers in Immunology

doi 10.3389/fimmu.2025.1707821

1,119 views

Review

Published on 09 Jan 2026

Immunological mechanisms underlying fibrotic diseases via single-cell technologies

in Autoimmune and Autoinflammatory Disorders: Autoinflammatory Disorders

Yuzo Koda
Nobuhiro Nakamoto
Takanori Kanai

Frontiers in Immunology

doi 10.3389/fimmu.2025.1720047

1,250 views

Original Research

Published on 05 Jan 2026

Influencing factor analysis and prediction model construction of dupilumab treatment adherence: a prospective cohort study in moderate-to-severe atopic dermatitis

in Autoimmune and Autoinflammatory Disorders: Autoinflammatory Disorders

Pingxiang Ouyang
Siyu Yan
Jinrong Zeng
Lihua Gao
Lina Tan
Jianyun Lu

Frontiers in Immunology

doi 10.3389/fimmu.2025.1682777

1,221 views

Original Research

Published on 17 Dec 2025

A comparative study of large-vessel and small-vessel primary angiitis of the central nervous system: insights from a Chinese single-center retrospective cohort

in Autoimmune and Autoinflammatory Disorders: Autoinflammatory Disorders

Yifan Wang
Jiangyi Lyu
Fangfang Li
Jing Zhao
Yu He
Shangtian Xiang
Weizhou Zang

Frontiers in Immunology

doi 10.3389/fimmu.2025.1724588

1,222 views

Review

Published on 16 Dec 2025

Pyroptosis-driven immune dysregulation in COPD: molecular mechanisms and therapeutic implications

in Autoimmune and Autoinflammatory Disorders: Autoinflammatory Disorders

Feng-Xian Ni
Hui-Xian Wang
Jie Hu
Pei-Sheng Chen
Hua-Jing Huang
Hui-Hui Chen
Dong-Hui Huang
Ze-Bo Jiang

Frontiers in Immunology

doi 10.3389/fimmu.2025.1686175

1,843 views

Mini Review

Accepted on 15 Dec 2025

Hemophagocytic Lymphohistiocytosis Induced by Immune Checkpoint Inhibitors: Observations and Proposed Clinical Management

in Autoimmune and Autoinflammatory Disorders: Autoinflammatory Disorders

Bianca Arianna Facchini
Benjamin Switzer
Marc S Ernstoff
Igor Puzanov
Paolo Antonio Ascierto

Frontiers in Immunology

359 views

Correction

Published on 15 Dec 2025

Correction: Association of clinical features and myositis-specific antibodies in idiopathic inflammatory myopathy: a retrospective study from southern China

in Autoimmune and Autoinflammatory Disorders: Autoinflammatory Disorders

Can Li
Yushi Zheng
Yu Zhang
Yujin Ye
Hui Zhang
Niansheng Yang
Shuang Wang

Frontiers in Immunology

doi 10.3389/fimmu.2025.1743471

848 views

551 articles

articles

Case Report: Upadacitinib for SAPHO syndrome with biologics-induced paradoxical manifestation and Hyperimmunoglobulinemia E

Clinical, immunological characterisation and treatment response of patients with syndrome of undifferentiated recurrent fever (SURF) in Chinese children and adolescents: a single-centre cohort study

Diverse Pediatric Phenotypes of RELA Frameshift Variants: Comparison of Two Cases

Ferroptosis as a Therapeutic Nexus: Traditional Chinese Medicine Interventions in Rheumatoid Arthritis

The evaluation of the plasma levels of interleukin 17A, thymic stromal lymphopoietin, interferon gamma, tumor necrosis factor-alpha and interleukins IL-2, IL-6, IL-23, and IL-31 in atopic dermatitis patients with dupilumab treatment

A fatal course of hemophagocytic lymphohistiocytosis in a child with homozygous ERCC6L2 defect and heterozygous ADA2 variant: a case report

Multi-omics analysis reveals the mechanism of verbenalin in treating gout via modulating purine metabolism, gut microbiota, and inflammatory pathways

Immunometabolism in Rheumatoid Arthritis: Mechanisms, Biomarkers, and the Path to Precision Medicine

Immune cell dynamics and mechanisms of epithelial injury in celiac disease

A 76-week real-world multidimensional analysis of guselkumab in moderate to severe plaque psoriasis: a retrospective cohort study based on Chinese clinical practice standards

Deciphering the immunocellular regulatory network in inflammatory bowel disease: from susceptibility genes to cellular effectors and toward precision therapies

Advances in the pathogenesis of rosacea

Hashimoto’s thyroiditis is associated with reduced invasiveness in papillary thyroid carcinoma: a propensity score-matched retrospective cohort study

Case Report: Diagnostic challenges in VEXAS syndrome with novel ultrastructural lung findings: IgG4-RD and vasculitis as relevant differential diagnoses

Impact of treatment interruption on the efficacy and safety of vunakizumab in patients with moderate-to-severe plaque psoriasis: a post-hoc analysis of a phase 3 trial

Exploring targeted therapy in retinal vasculopathy with cerebral leukoencephalopathy: a case report and review of literature

Targeted degradation of MK2 is insufficient to block inflammatory cytokine production in human cells due to cooperativity with MK3 and MK5

A multi-omics analysis of pancreatitis: bridging familial genetics and disease progression

Immunological mechanisms underlying fibrotic diseases via single-cell technologies

Influencing factor analysis and prediction model construction of dupilumab treatment adherence: a prospective cohort study in moderate-to-severe atopic dermatitis

A comparative study of large-vessel and small-vessel primary angiitis of the central nervous system: insights from a Chinese single-center retrospective cohort

Pyroptosis-driven immune dysregulation in COPD: molecular mechanisms and therapeutic implications

Hemophagocytic Lymphohistiocytosis Induced by Immune Checkpoint Inhibitors: Observations and Proposed Clinical Management

Correction: Association of clinical features and myositis-specific antibodies in idiopathic inflammatory myopathy: a retrospective study from southern China