Frontiers in Immunology | B Cell Biology

Original Research

Published on 12 Mar 2018

Acquisition of N-Glycosylation Sites in Immunoglobulin Heavy Chain Genes During Local Expansion in Parotid Salivary Glands of Primary Sjögren Patients

in B Cell Biology

Annie Visser
Marieke E. Doorenspleet
Niek de Vries
Fred K. L. Spijkervet
Arjan Vissink
Richard J. Bende
Hendrika Bootsma
Frans G. M. Kroese
Nicolaas A. Bos

Frontiers in Immunology

doi 10.3389/fimmu.2018.00491

4,203 views
16 citations

Original Research

Published on 08 Mar 2018

Many Routes to an Antibody Heavy-Chain CDR3: Necessary, Yet Insufficient, for Specific Binding

in B Cell Biology

Sara D’Angelo
Fortunato Ferrara
Leslie Naranjo
M. Frank Erasmus
Peter Hraber
Andrew R. M. Bradbury

Frontiers in Immunology

doi 10.3389/fimmu.2018.00395

33,243 views
95 citations

Original Research

Published on 08 Mar 2018

Variable Extent of Lineage-Specificity and Developmental Stage-Specificity of Cohesin and CCCTC-Binding Factor Binding Within the Immunoglobulin and T Cell Receptor Loci

in B Cell Biology

Salvatore Loguercio
E. Mauricio Barajas-Mora
Han-Yu Shih
Michael S. Krangel
Ann J. Feeney

Frontiers in Immunology

doi 10.3389/fimmu.2018.00425

7,747 views
34 citations

Mini Review

Published on 08 Mar 2018

New Insights into Tumor-Infiltrating B Lymphocytes in Breast Cancer: Clinical Impacts and Regulatory Mechanisms

in B Cell Biology

Meng Shen
Jian Wang
Xiubao Ren

Frontiers in Immunology

doi 10.3389/fimmu.2018.00470

16,383 views
82 citations

Review

Published on 08 Mar 2018

Tailoring Immune Responses toward Autoimmunity: Transcriptional Regulators That Drive the Creation and Collusion of Autoreactive Lymphocytes

in B Cell Biology

Kim L. Good-Jacobson
Joanna R. Groom

Frontiers in Immunology

doi 10.3389/fimmu.2018.00482

5,678 views
11 citations

Perspective

Published on 07 Mar 2018

Strategies for Generating Diverse Antibody Repertoires Using Transgenic Animals Expressing Human Antibodies

in B Cell Biology

Weihsu C. Chen
Christopher M. Murawsky

Frontiers in Immunology

doi 10.3389/fimmu.2018.00460

20,425 views
38 citations

Review

Published on 06 Mar 2018

TANK-Binding Kinase 1-Dependent Responses in Health and Autoimmunity

in B Cell Biology

Cynthia Louis
Chris Burns
Ian Wicks

Frontiers in Immunology

doi 10.3389/fimmu.2018.00434

14,662 views
67 citations

Original Research

Published on 02 Mar 2018

Repertoire Analysis of Antibody CDR-H3 Loops Suggests Affinity Maturation Does Not Typically Result in Rigidification

in B Cell Biology

Jeliazko R. Jeliazkov
Adnan Sljoka
Daisuke Kuroda
Nobuyuki Tsuchimura
Naoki Katoh
Kouhei Tsumoto
Jeffrey J. Gray

Frontiers in Immunology

doi 10.3389/fimmu.2018.00413

15,919 views
57 citations

Original Research

Published on 01 Mar 2018

Coupling of Single Molecule, Long Read Sequencing with IMGT/HighV-QUEST Analysis Expedites Identification of SIV gp140-Specific Antibodies from scFv Phage Display Libraries

in B Cell Biology

Seung Yub Han
Alesia Antoine
David Howard
Bryant Chang
Woo Sung Chang
Matthew Slein
Gintaras Deikus
Sofia Kossida
Patrice Duroux
Marie-Paule Lefranc

Frontiers in Immunology

doi 10.3389/fimmu.2018.00329

11,862 views
18 citations

Review

Published on 01 Mar 2018

Lyn, Lupus, and (B) Lymphocytes, a Lesson on the Critical Balance of Kinase Signaling in Immunity

in B Cell Biology

Erica J. Brodie
Simona Infantino
Michael S. Y. Low
David M. Tarlinton

Frontiers in Immunology

doi 10.3389/fimmu.2018.00401

13,197 views
57 citations

Original Research

Published on 28 Feb 2018

PTEN-Regulated AID Transcription in Germinal Center B Cells Is Essential for the Class-Switch Recombination and IgG Antibody Responses

in B Cell Biology

Jing Wang
Sichen Liu
Baidong Hou
Meixiang Yang
Zhongjun Dong
Hai Qi
Wanli Liu

Frontiers in Immunology

doi 10.3389/fimmu.2018.00371

9,634 views
13 citations

Review

Published on 26 Feb 2018

Epigenomic Modifications Mediating Antibody Maturation

in B Cell Biology

Emily C. Sheppard
Rikke Brandstrup Morrish
Michael J. Dillon
Rebecca Leyland
Richard Chahwan

Frontiers in Immunology

doi 10.3389/fimmu.2018.00355

9,829 views
32 citations

Original Research

Published on 26 Feb 2018

Genome-Wide Association Study on Immunoglobulin G Glycosylation Patterns

in B Cell Biology

Annika Wahl
Erik van den Akker
Lucija Klaric
Jerko Štambuk
Elisa Benedetti
Rosina Plomp
Genadij Razdorov
Irena Trbojević-Akmačić
Joris Deelen
Diana van Heemst

Frontiers in Immunology

doi 10.3389/fimmu.2018.00277

15,112 views
77 citations

Review

Published on 21 Feb 2018

Computational Strategies for Dissecting the High-Dimensional Complexity of Adaptive Immune Repertoires

in B Cell Biology

Enkelejda Miho
Alexander Yermanos
Cédric R. Weber
Christoph T. Berger
Sai T. Reddy
Victor Greiff

Frontiers in Immunology

doi 10.3389/fimmu.2018.00224

34,619 views
196 citations

Original Research

Published on 19 Feb 2018

A Novel Role for C5a in B-1 Cell Homeostasis

in B Cell Biology

Katharina Bröker
Julia Figge
Albert F. Magnusen
Rudolf A. Manz
Jörg Köhl
Christian M. Karsten

Frontiers in Immunology

doi 10.3389/fimmu.2018.00258

11,152 views
24 citations

Original Research

Published on 16 Feb 2018

The Rac Activator DOCK2 Mediates Plasma Cell Differentiation and IgG Antibody Production

in B Cell Biology

Miho Ushijima
Takehito Uruno
Akihiko Nishikimi
Fumiyuki Sanematsu
Yasuhisa Kamikaseda
Kazufumi Kunimura
Daiji Sakata
Takaharu Okada
Yoshinori Fukui

Frontiers in Immunology

doi 10.3389/fimmu.2018.00243

7,928 views
19 citations

Original Research

Published on 07 Feb 2018

In the Absence of Central pre-B Cell Receptor Selection, Peripheral Selection Attempts to Optimize the Antibody Repertoire by Enriching for CDR-H3 Y101

in B Cell Biology

Mohamed Khass
Tessa Blackburn
Ada Elgavish
Peter D. Burrows
Harry W. Schroeder

Frontiers in Immunology

doi 10.3389/fimmu.2018.00120

4,458 views
4 citations

Mini Review

Published on 07 Feb 2018

Signal Transducer and Activator of Transcription 3 Control of Human T and B Cell Responses

in B Cell Biology

Elissa K. Deenick
Simon J. Pelham
Alisa Kane
Cindy S. Ma

Frontiers in Immunology

doi 10.3389/fimmu.2018.00168

12,484 views
73 citations

Original Research

Published on 05 Feb 2018

In-Depth Analysis of Human Neonatal and Adult IgM Antibody Repertoires

in B Cell Biology

Binbin Hong
Yanling Wu
Wei Li
Xun Wang
Yumei Wen
Shibo Jiang
Dimiter S. Dimitrov
Tianlei Ying

Frontiers in Immunology

doi 10.3389/fimmu.2018.00128

9,314 views
30 citations

Original Research

Published on 05 Feb 2018

Fcµ Receptor Promotes the Survival and Activation of Marginal Zone B Cells and Protects Mice against Bacterial Sepsis

in B Cell Biology

Jun Liu
Hanying Zhu
Jiawen Qian
Ermeng Xiong
Lumin Zhang
Yan-Qing Wang
Yiwei Chu
Hiromi Kubagawa
Takeshi Tsubata
Ji-Yang Wang

Frontiers in Immunology

doi 10.3389/fimmu.2018.00160

6,969 views
19 citations

Mini Review

Published on 02 Feb 2018

Next-Generation Sequencing of Antibody Display Repertoires

in B Cell Biology

Romain Rouet
Katherine J. L. Jackson
David B. Langley
Daniel Christ

Frontiers in Immunology

doi 10.3389/fimmu.2018.00118

33,929 views
91 citations

Review

Published on 01 Feb 2018

Insights into the Structural Basis of Antibody Affinity Maturation from Next-Generation Sequencing

in B Cell Biology

Arjun K. Mishra
Roy A. Mariuzza

Frontiers in Immunology

doi 10.3389/fimmu.2018.00117

44,546 views
100 citations

Original Research

Published on 31 Jan 2018

Fc-Glycosylation in Human IgG1 and IgG3 Is Similar for Both Total and Anti-Red-Blood Cell Anti-K Antibodies

in B Cell Biology

Myrthe E. Sonneveld
Carolien A. M. Koeleman
H. Rosina Plomp
Manfred Wuhrer
C. Ellen van der Schoot
Gestur Vidarsson

Frontiers in Immunology

doi 10.3389/fimmu.2018.00129

10,281 views
27 citations

Original Research

Published on 24 Jan 2018

Induction of Short NFATc1/αA Isoform Interferes with Peripheral B Cell Differentiation

in B Cell Biology

Khalid Muhammad
Ronald Rudolf
Duong Anh Thuy Pham
Stefan Klein-Hessling
Katsuyoshi Takata
Nobuko Matsushita
Volker Ellenrieder
Eisaku Kondo
Edgar Serfling

Frontiers in Immunology

doi 10.3389/fimmu.2018.00032

6,240 views
6 citations

1,037 articles

articles

Acquisition of N-Glycosylation Sites in Immunoglobulin Heavy Chain Genes During Local Expansion in Parotid Salivary Glands of Primary Sjögren Patients

Many Routes to an Antibody Heavy-Chain CDR3: Necessary, Yet Insufficient, for Specific Binding

Variable Extent of Lineage-Specificity and Developmental Stage-Specificity of Cohesin and CCCTC-Binding Factor Binding Within the Immunoglobulin and T Cell Receptor Loci

New Insights into Tumor-Infiltrating B Lymphocytes in Breast Cancer: Clinical Impacts and Regulatory Mechanisms

Tailoring Immune Responses toward Autoimmunity: Transcriptional Regulators That Drive the Creation and Collusion of Autoreactive Lymphocytes

Strategies for Generating Diverse Antibody Repertoires Using Transgenic Animals Expressing Human Antibodies

TANK-Binding Kinase 1-Dependent Responses in Health and Autoimmunity

Repertoire Analysis of Antibody CDR-H3 Loops Suggests Affinity Maturation Does Not Typically Result in Rigidification

Coupling of Single Molecule, Long Read Sequencing with IMGT/HighV-QUEST Analysis Expedites Identification of SIV gp140-Specific Antibodies from scFv Phage Display Libraries

Lyn, Lupus, and (B) Lymphocytes, a Lesson on the Critical Balance of Kinase Signaling in Immunity

PTEN-Regulated AID Transcription in Germinal Center B Cells Is Essential for the Class-Switch Recombination and IgG Antibody Responses

Epigenomic Modifications Mediating Antibody Maturation

Genome-Wide Association Study on Immunoglobulin G Glycosylation Patterns

Computational Strategies for Dissecting the High-Dimensional Complexity of Adaptive Immune Repertoires

A Novel Role for C5a in B-1 Cell Homeostasis

The Rac Activator DOCK2 Mediates Plasma Cell Differentiation and IgG Antibody Production

In the Absence of Central pre-B Cell Receptor Selection, Peripheral Selection Attempts to Optimize the Antibody Repertoire by Enriching for CDR-H3 Y101

Signal Transducer and Activator of Transcription 3 Control of Human T and B Cell Responses

In-Depth Analysis of Human Neonatal and Adult IgM Antibody Repertoires

Fcµ Receptor Promotes the Survival and Activation of Marginal Zone B Cells and Protects Mice against Bacterial Sepsis

Next-Generation Sequencing of Antibody Display Repertoires

Insights into the Structural Basis of Antibody Affinity Maturation from Next-Generation Sequencing

Fc-Glycosylation in Human IgG1 and IgG3 Is Similar for Both Total and Anti-Red-Blood Cell Anti-K Antibodies

Induction of Short NFATc1/αA Isoform Interferes with Peripheral B Cell Differentiation