Frontiers in Immunology | Cancer Immunity and Immunotherapy

Original Research

Published on 08 May 2025

Development of a lung immune prognostic index-based nomogram model for predicting overall survival and immune-related adverse events in non-small cell lung cancer patients treated with sintilimab

in Cancer Immunity and Immunotherapy

Jian Xu
Tingting Peng
Kaikai Fan
Yuxiao Dou
Lingti Kong
Ran Sang

Frontiers in Immunology

doi 10.3389/fimmu.2025.1569689

2,369 views

Original Research

Published on 08 May 2025

Oncologic outcomes following neoadjuvant immunochemotherapy in locally advanced oral squamous cell carcinoma

in Cancer Immunity and Immunotherapy

Gang Li
Jiheng Wang
Qigen Fang
Liyuan Dai
Wei Du

Frontiers in Immunology

doi 10.3389/fimmu.2025.1571285

1,552 views
1 citation

Review

Published on 08 May 2025

Immunomodulatory role of RNA modifications in sex hormone-dependent cancers

in Cancer Immunity and Immunotherapy

Yujia Jiang
Xiaolan Liang
Hongyi Sun
Ping Yin
Jing Zhou
Chaoqin Yu

Frontiers in Immunology

doi 10.3389/fimmu.2025.1513037

2,180 views
1 citation

Editorial

Published on 08 May 2025

Editorial: Exploring macrophage roles in cancer progression and therapeutic targeting

in Cancer Immunity and Immunotherapy

George S. Karagiannis
Yu Kato
David Entenberg

Frontiers in Immunology

doi 10.3389/fimmu.2025.1612588

1,042 views

Case Report

Published on 08 May 2025

Case Report: Bispecific CD20/CD30-targeted chimeric antigen receptor T-cell therapy for non-Hodgkin’s lymphoma

in Cancer Immunity and Immunotherapy

Yuejiao Huang
Yiming Gong
Xiang Liu
Huaying Ruan
Jinhua Lu
Hosein Kouros-Mehr
Hong Liu
Han Wang

Frontiers in Immunology

doi 10.3389/fimmu.2025.1567149

2,205 views

Original Research

Published on 08 May 2025

Translating genetics into tissue: inflammatory cytokine-producing TAMs and PD-L1 tumor expression as poor prognosis factors in cutaneous melanoma

in Cancer Immunity and Immunotherapy

Celia Barrio-Alonso
Alicia Nieto-Valle
Lucía Barandalla-Revilla
José Antonio Avilés-Izquierdo
Verónica Parra-Blanco
Paloma Sánchez-Mateos
Rafael Samaniego

Frontiers in Immunology

doi 10.3389/fimmu.2025.1587545

1,597 views
1 citation

Original Research

Published on 08 May 2025

Multi-omics analysis and experiments uncover the link between cancer intrinsic drivers, stemness, and immunotherapy in ovarian cancer with validation in a pan-cancer census

in Cancer Immunity and Immunotherapy

Yilin Li
Cen Chen
Xiaoyu Ji
Ningxiao Jiang
Fei Wang
Xiangqian Gao
Weiwei Chen
Qiang Tang
Yan Li
Shinan Zhang

Frontiers in Immunology

doi 10.3389/fimmu.2025.1549656

2,400 views

Original Research

Published on 08 May 2025

Personalized treatment decision-making using a machine learning-derived lactylation signature for breast cancer prognosis

in Cancer Immunity and Immunotherapy

Simin Min
Xiaonan Zhang
Yuling Liu
Weiqiang Wang
Jingwen Guan
Yuyan Chen
Meng Sun
Ziheng Wang
Tao Wang

Frontiers in Immunology

doi 10.3389/fimmu.2025.1540018

3,233 views

Original Research

Published on 08 May 2025

A conceptual exploration on the synergistic anti-tumor effects of high-order combination of OHSV2-DSTEFAP5/CD3, CAR-T cells, and immunotoxins in hepatocellular carcinoma

in Cancer Immunity and Immunotherapy

Shuang Dong
Xin Chen
Xiaoyu Li
Yang Wang
Qing Huang
Yuanxiang Li
Jing Jin
Xianmin Zhu
Yi Zhong
Qian Cai

Frontiers in Immunology

doi 10.3389/fimmu.2025.1509087

2,648 views

Review

Published on 08 May 2025

Recent advances in biomarkers for predicting the efficacy of immunotherapy in non-small cell lung cancer

in Cancer Immunity and Immunotherapy

Jiacheng Zhang
Zehao Song
Yuanjie Zhang
Chentong Zhang
Qi Xue
Guochao Zhang
Fengwei Tan

Frontiers in Immunology

doi 10.3389/fimmu.2025.1554871

3,892 views
1 citation

Original Research

Published on 08 May 2025

Single-cell RNA sequencing reveals adrb1 as a sympathetic nerve-regulated immune checkpoint driving T cell exhaustion and impacting immunotherapy in esophageal squamous cell carcinoma

in Cancer Immunity and Immunotherapy

Qun Li
Shuning Xu
Yulin Ren
Cheng Zhang
Ke Li
Ying Liu

Frontiers in Immunology

doi 10.3389/fimmu.2025.1520766

3,203 views

Original Research

Published on 08 May 2025

Bibliometric analysis of traditional Chinese medicine in cancer treatment via immune system modulation (2015–2025)

in Cancer Immunity and Immunotherapy

Youfeng Lei
Chunyan Chen

Frontiers in Immunology

doi 10.3389/fimmu.2025.1581885

2,887 views

Original Research

Published on 08 May 2025

High expression of CXCL13 predicts a favorable response to immunotherapy by upregulating CXCR5+CD8+ T-cell infiltration in gastric cancer

in Cancer Immunity and Immunotherapy

Shuning Xu
Danyang Li
Tao Ning
Yao Lu
Yansha Sun
Hua Bai
Lei Qiao
Ting Deng
Ying Liu

Frontiers in Immunology

doi 10.3389/fimmu.2025.1551259

2,400 views
2 citations

Original Research

Published on 08 May 2025

Decoding multiple myeloma: single-cell insights into tumor heterogeneity, immune dynamics, and disease progression

in Cancer Immunity and Immunotherapy

Zhenzhen Zhao
Zhijie Zhao
Zhiheng Lin
Lu Fan
Zhikai Xiahou
Yujiang Dong
Weiying Bao

Frontiers in Immunology

doi 10.3389/fimmu.2025.1584350

3,027 views
9 citations

Original Research

Published on 08 May 2025

Identification of SCAMP2 as a regulator of NOTCH signaling in cisplatin resistance through a novel prognostic model for bladder cancer

in Cancer Immunity and Immunotherapy

Longjun Cai
Shaoqi Zhang
Fangfang Zheng
Furong Ji
Jin Wang
Long Shi
Liu Chao
Xiangyu Wang
Jianjun Zhang
Zhiyong Chen

Frontiers in Immunology

doi 10.3389/fimmu.2025.1573412

3,875 views

Original Research

Published on 08 May 2025

Identification of common hub genes and construction of immune regulatory networks in aplastic anemia, myelodysplastic syndromes, and acute myeloid leukemia

in Cancer Immunity and Immunotherapy

Mingliang Shan
Li Xu
Wenzhe Yang
Lili Sui
Ping Sun
Xiumei Zhuo
Shiguo Liu

Frontiers in Immunology

doi 10.3389/fimmu.2025.1547289

3,086 views