Frontiers in Immunology | Immunological Tolerance and Regulation

Original Research

Published on 09 May 2025

Cervical EVT isolation for non-invasive fetal HLA typing in early pregnancy is limited by purity and maternal cell contamination; a methodological comparison

in Immunological Tolerance and Regulation

Liseanne J. van ‘t Hof
Johanna M. Kapsenberg
Jos J.M. Drabbels
Lotte E. van der Meeren
Dave L. Roelen
Michael Eikmans
Marie-Louise P. van der Hoorn

Frontiers in Immunology

doi 10.3389/fimmu.2025.1575086

2,871 views
2 citations

Original Research

Published on 05 May 2025

TRIM28 mediates Mettl5 ubiquitination to promotes Th2 polarization

in Immunological Tolerance and Regulation

Beiping Miao
Lihua Mo
Shihan Miao
Xiwen Zhang
Haoyue Zheng
Yixuan Dong
Bailing Xie
Yuanyi Zhang
Yun Liao
Yu Liu

Frontiers in Immunology

doi 10.3389/fimmu.2025.1524633

2,780 views
1 citation

Review

Published on 30 Apr 2025

Trends and hotspots on hymenoptera venom immunotherapy: a bibliometric and visualized analysis of research from 2014 to 2024

in Immunological Tolerance and Regulation

Yun Luo
Minxia Guan
Yichuan Yu

Frontiers in Immunology

doi 10.3389/fimmu.2025.1546704

3,201 views
1 citation

Original Research

Published on 30 Apr 2025

The CD38+HLA-DR+ T cells with activation and exhaustion characteristics as predictors of severity and mortality in COVID-19 patients

in Immunological Tolerance and Regulation

Qiuyue Long
Shixu Song
Jianbo Xue
Wenyi Yu
Yaolin Zheng
Jiwei Li
Jing Wu
Xiaoyi Hu
Mingzheng Jiang
Hongli Ye

Frontiers in Immunology

doi 10.3389/fimmu.2025.1577803

5,543 views
5 citations

Correction

Published on 25 Apr 2025

Corrigendum: Infection of a β-galactosidase-deficient mouse strain with Theiler’s murine encephalomyelitis virus reveals limited immunological dysregulations in this lysosomal storage disease

in Immunological Tolerance and Regulation

Rouven Wannemacher
Felix Stegmann
Deborah Eikelberg
Melanie Bühler
Dandan Li
Sayali Kalidas Kohale
Thanaporn Asawapattanakul
Tim Ebbecke
Marie-Kristin Raulf
Wolfgang Baumgärtner

Frontiers in Immunology

doi 10.3389/fimmu.2025.1610299

1,378 views

Original Research

Published on 22 Apr 2025

High-resolution transcriptional impact of AIRE: effects of pathogenic variants p.Arg257Ter, p.Cys311Tyr, and polygenic risk variant p.Arg471Cys

in Immunological Tolerance and Regulation

Amund Holte Berger
Bergithe Eikeland Oftedal
Anette Susanne Bøe Wolff
Eystein Sverre Husebye
Per Morten Knappskog
Eirik Bratland
Stefan Johansson

Frontiers in Immunology

doi 10.3389/fimmu.2025.1572789

2,695 views
2 citations

Review

Published on 22 Apr 2025

Scientific developments in understanding food allergy prevention, diagnosis, and treatment

in Immunological Tolerance and Regulation

Shirin Karimi Hund
Vanitha Sampath
Xiaoying Zhou
Bryan Thai
Khushi Desai
Kari C. Nadeau

Frontiers in Immunology

doi 10.3389/fimmu.2025.1572283

9,757 views
5 citations

Original Research

Published on 16 Apr 2025

The single-cell atlas of short-chain fatty acid receptors in human and mice hearts

in Immunological Tolerance and Regulation

Xiaojun He
Qiang Wang
Qiang Long
Yiming Zhong
Zhaoxi Qi
Yecen Zhang
Lan Chang
Bei Qian
Shixing Huang
Xinming Wang

Frontiers in Immunology

doi 10.3389/fimmu.2025.1538384

3,754 views
1 citation

Original Research

Published on 15 Apr 2025

Helicobacter pylori outer membrane vesicles mediate central tolerance in C57BL/6J mice offspring T cells via maternal-fetal transmission

in Immunological Tolerance and Regulation

Yusen Wei
Lu Zhou
Xiaofei Zhao
Huiqing Qiu
Dailun Hu
Zhongli Shi

Frontiers in Immunology

doi 10.3389/fimmu.2025.1522842

3,361 views
1 citation

Original Research

Published on 11 Apr 2025

A dominant, pan-DR binding epitope of Der p 1 in house dust mite allergy induces tolerance in HLA-DR4 transgenic mice

in Immunological Tolerance and Regulation

Heather B. Streeter
Lora G. Lucas
Robert M. West
Mamidipudi T. Krishna
David C. Wraith

Frontiers in Immunology

doi 10.3389/fimmu.2025.1569283

3,616 views

Original Research

Published on 09 Apr 2025

Therapeutic effects of Isaria felina on postmenopausal osteoporosis: modulation of gut microbiota, metabolites, and immune responses

in Immunological Tolerance and Regulation

Xiaoyan Li
Chenhui Xue
Yongming Yang
Lili Zhao
Lixia Chen
Jing Wang
Lei Yan
Zan Meng
Xiaochen Qiao
Sujiao Liang

Frontiers in Immunology

doi 10.3389/fimmu.2025.1508634

5,087 views
2 citations

Original Research

Published on 09 Apr 2025

Infection of a β-galactosidase-deficient mouse strain with Theiler’s murine encephalomyelitis virus reveals limited immunological dysregulations in this lysosomal storage disease

in Immunological Tolerance and Regulation

Rouven Wannemacher
Felix Stegmann
Deborah Eikelberg
Melanie Bühler
Dandan Li
Sayali Kalidas Kohale
Thanaporn Asawapattanakul
Tim Ebbecke
Marie-Kristin Raulf
Wolfgang Baumgärtner

Frontiers in Immunology

doi 10.3389/fimmu.2025.1467207

2,577 views
1 citation

Original Research

Published on 08 Apr 2025

Identification of Dinaciclib and Ganetespib as anti-inflammatory drugs using a novel HTP screening assay that targets IFNγ-dependent PD-L1

in Immunological Tolerance and Regulation

Shira Hagbi-Levi
Michal Abraham
Lika Gamaev
Inbal Mishaelian
Ophir Hay
Elina Zorde-Khevalevsky
Ori Wald
Hanna Wald
Devorah Olam
Lola Weiss

Frontiers in Immunology

doi 10.3389/fimmu.2025.1502094

2,672 views
1 citation

Original Research

Published on 07 Apr 2025

Endometrial immune assessment in patients with a history of previous euploid blastocyst failure

in Immunological Tolerance and Regulation

Jemma Garratt
Baharak Mohammadi
Balsam Al-Hashimi
Elena Linara-Demakakou
Rukma Bhattacharya
Kamal K. Ahuja
Nick Macklon
Mona Rahmati

Frontiers in Immunology

doi 10.3389/fimmu.2025.1547159

3,107 views
2 citations

Mini Review

Published on 01 Apr 2025

Progress in the application of molecular imaging technology in immunological tolerance and immune metabolism visualization research

in Immunological Tolerance and Regulation

Kailang Li
Fang Xie
Yongfu Xiong
Jin Jiang
Bifan Huang

Frontiers in Immunology

doi 10.3389/fimmu.2025.1583228

2,072 views
1 citation

Review

Published on 27 Mar 2025

Dynamic regulation of neutrophil immunometabolism by platelet-derived metabolites

in Immunological Tolerance and Regulation

Manuel Alejandro Mosso-Pani
Dante Barreda
Ma. Isabel Salazar

Frontiers in Immunology

doi 10.3389/fimmu.2025.1542438

5,822 views
5 citations

Systematic Review

Published on 25 Mar 2025

Effects of isolated, confined and extreme environments on parameters of the immune system - a systematic review

in Immunological Tolerance and Regulation

Bea Klos
Alina Kaul
Emily Straube
Verena Steinhauser
Celina Gödel
Franziska Schäfer
Claude Lambert
Paul Enck
Isabelle Mack

Frontiers in Immunology

doi 10.3389/fimmu.2025.1532103

4,167 views
11 citations

Review

Published on 20 Mar 2025

Restoring immune tolerance in pre-RA: immunometabolic dialogue between gut microbiota and regulatory T cells

in Immunological Tolerance and Regulation

Anqi Gao
Ruihe Wu
Yanfei Mu
Ruqing Jin
Saixin Jiang
Chong Gao
Xiaofeng Li
Caihong Wang

Frontiers in Immunology

doi 10.3389/fimmu.2025.1565133

4,655 views
5 citations

Mini Review

Published on 19 Mar 2025

Iron and energy metabolic interactions in Treg-mediated immune regulation

in Immunological Tolerance and Regulation

Frédérique Savagner
Thomas Farge
Zoubida Karim
Meryem Aloulou

Frontiers in Immunology

doi 10.3389/fimmu.2025.1554028

4,608 views
1 citation

Original Research

Published on 19 Mar 2025

CXCR2P1 enhances the response of gastric cancer to PD-1 inhibitors through increasing the immune infiltration of tumors

in Immunological Tolerance and Regulation

Xinchun Wu
Sen Hou
Yingjiang Ye
Zhidong Gao

Frontiers in Immunology

doi 10.3389/fimmu.2025.1545605

4,192 views
3 citations

Hypothesis and Theory

Published on 14 Mar 2025

The impact of the mRNA COVID-19 vaccine on the Th-like cytokine profile in individuals with no history of COVID-19: insights into autoimmunity targeting heat shock proteins

in Immunological Tolerance and Regulation

Stefan Tukaj
Magdalena Sitna
Krzysztof Sitko

Frontiers in Immunology

doi 10.3389/fimmu.2025.1549739

7,022 views
1 citation

Original Research

Published on 07 Mar 2025

Identification and analysis of oxidative stress-related genes in endometriosis

in Immunological Tolerance and Regulation

Chengmao Xie
Chang Lu
Na Lv
Weimin Kong
Yong Liu

Frontiers in Immunology

doi 10.3389/fimmu.2025.1515490

3,820 views
5 citations

Opinion

Published on 03 Mar 2025

Immune modulatory stem cells represent a significant component of the immune system

in Immunological Tolerance and Regulation

Dmitriy Vladimirovich Karpenko

Frontiers in Immunology

doi 10.3389/fimmu.2025.1543495

2,404 views
2 citations

Review

Published on 28 Feb 2025

From cold to hot: mechanisms of hyperthermia in modulating tumor immunology for enhanced immunotherapy

in Immunological Tolerance and Regulation

M. Marc Abreu
Alberto F. Chocron
David M. Smadja

Frontiers in Immunology

doi 10.3389/fimmu.2025.1487296

9,236 views
25 citations

1,665 articles

articles

Cervical EVT isolation for non-invasive fetal HLA typing in early pregnancy is limited by purity and maternal cell contamination; a methodological comparison

TRIM28 mediates Mettl5 ubiquitination to promotes Th2 polarization

Trends and hotspots on hymenoptera venom immunotherapy: a bibliometric and visualized analysis of research from 2014 to 2024

The CD38+HLA-DR+ T cells with activation and exhaustion characteristics as predictors of severity and mortality in COVID-19 patients

Corrigendum: Infection of a β-galactosidase-deficient mouse strain with Theiler’s murine encephalomyelitis virus reveals limited immunological dysregulations in this lysosomal storage disease

High-resolution transcriptional impact of AIRE: effects of pathogenic variants p.Arg257Ter, p.Cys311Tyr, and polygenic risk variant p.Arg471Cys

Scientific developments in understanding food allergy prevention, diagnosis, and treatment

The single-cell atlas of short-chain fatty acid receptors in human and mice hearts

Helicobacter pylori outer membrane vesicles mediate central tolerance in C57BL/6J mice offspring T cells via maternal-fetal transmission

A dominant, pan-DR binding epitope of Der p 1 in house dust mite allergy induces tolerance in HLA-DR4 transgenic mice

Therapeutic effects of Isaria felina on postmenopausal osteoporosis: modulation of gut microbiota, metabolites, and immune responses

Infection of a β-galactosidase-deficient mouse strain with Theiler’s murine encephalomyelitis virus reveals limited immunological dysregulations in this lysosomal storage disease

Identification of Dinaciclib and Ganetespib as anti-inflammatory drugs using a novel HTP screening assay that targets IFNγ-dependent PD-L1

Endometrial immune assessment in patients with a history of previous euploid blastocyst failure

Progress in the application of molecular imaging technology in immunological tolerance and immune metabolism visualization research

Dynamic regulation of neutrophil immunometabolism by platelet-derived metabolites

Effects of isolated, confined and extreme environments on parameters of the immune system - a systematic review

Restoring immune tolerance in pre-RA: immunometabolic dialogue between gut microbiota and regulatory T cells

Iron and energy metabolic interactions in Treg-mediated immune regulation

CXCR2P1 enhances the response of gastric cancer to PD-1 inhibitors through increasing the immune infiltration of tumors

The impact of the mRNA COVID-19 vaccine on the Th-like cytokine profile in individuals with no history of COVID-19: insights into autoimmunity targeting heat shock proteins

Identification and analysis of oxidative stress-related genes in endometriosis

Immune modulatory stem cells represent a significant component of the immune system

From cold to hot: mechanisms of hyperthermia in modulating tumor immunology for enhanced immunotherapy