Frontiers in Immunology

Mini Review

Published on 13 Aug 2025

Extracellular vesicles in osteoarthritis: mechanisms, therapeutic potential, and diagnostic applications

in Inflammation

Chongxiao Sun
Fei Teng
Yayi Xia

Frontiers in Immunology

doi 10.3389/fimmu.2025.1595095

4,490 views
1 citation

Systematic Review

Published on 12 Aug 2025

The role of TGF-β superfamily in endometriosis: a systematic review

in Inflammation

Xinyi Xu
Jun Li
He Lin
Zhe Lin
Guangcheng Ji

Frontiers in Immunology

doi 10.3389/fimmu.2025.1638604

4,810 views
1 citation

Review

Published on 12 Aug 2025

Oxidative stress and inflammation: roles in osteoporosis

in Inflammation

Jing Luo
Li Li
Wensen Shi
Kangjie Xu
Yucheng Shen
Bin Dai

Frontiers in Immunology

doi 10.3389/fimmu.2025.1611932

10,875 views
24 citations

Original Research

Published on 11 Aug 2025

Pregnancy exacerbates neutrophil responses in murine lungs and alters gut microbiota composition after cigarette smoke exposure

in Inflammation

Ali Dehghani
Lei Wang
Johan Garssen
Eirini Styla
Thea Leusink-Muis
Ingrid van Ark
Gert Folkerts
Jeroen van Bergenhenegouwen
Saskia Braber

Frontiers in Immunology

doi 10.3389/fimmu.2025.1590290

2,762 views
1 citation

Review

Published on 11 Aug 2025

Single-cell multi-omics-based immune temporal network resolution in sepsis: unravelling molecular mechanisms and precise therapeutic targets

in Inflammation

Han Liu
Qun Liang

Frontiers in Immunology

doi 10.3389/fimmu.2025.1616794

5,189 views
2 citations

Original Research

Published on 07 Aug 2025

Therapeutic potential of formononetin in cirrhotic portal hypertension: modulating hepatic fibrosis, macrophage polarization, and lymphangiogenesis

in Inflammation

Zhenghao Wu
Guqing Luo
Hongjie Li
Min Chen
Guangbo Wu
Qiang Fan
Chihao Zhang
Jiwei Yu
Jiayun Lin
Jinbo Zhao

Frontiers in Immunology

doi 10.3389/fimmu.2025.1571007

3,043 views
1 citation

Review

Published on 06 Aug 2025

Alveolar epithelial cells in bacterial sepsis-associated acute lung injury: mechanisms and therapeutic strategies

in Inflammation

Guiyang Jia
Erqin Song
Zhiyou Zheng
Mingjiang Qian
Guoyue Liu

Frontiers in Immunology

doi 10.3389/fimmu.2025.1605797

5,809 views
4 citations

Review

Published on 06 Aug 2025

MiRNA-loaded MSC exosomes restore autophagy flux for acute pancreatitis therapy

in Inflammation

Haojie Zeng
Tonghua Wu
Si Luo
Anxiang Zeng

Frontiers in Immunology

doi 10.3389/fimmu.2025.1613716

3,268 views
2 citations

Case Report

Published on 05 Aug 2025

Case Report: Low pressure hyperbaric oxygen therapy as a potential alternative treatment for chronic inflammatory response syndrome: a case study with notable improvements in fatigue, cognition, and testing

in Inflammation

Kristen L. Coletti Giesler

Frontiers in Immunology

doi 10.3389/fimmu.2025.1564788

4,608 views
2 citations

Original Research

Published on 05 Aug 2025

miR-210 promotes the anti-inflammatory phenotype and M2 polarization in murine macrophages

in Inflammation

Carmen Alexandra Neculachi
Evelyn-Gabriela Nastase-Rusu
Laudy Cherry
Catalina Iolanda Marinescu-Colan
Spyros Tastsoglou
Bogdan Paul Cosman
Alina Madalina Popa
Cristina Panciuc
Germana Zaccagnini
Sergiu Bogdan Catrina

Frontiers in Immunology

doi 10.3389/fimmu.2025.1633163

3,126 views
2 citations

Original Research

Published on 04 Aug 2025

The age of obesity onset affects changes in subcutaneous adipose tissue macrophages and T cells after weight loss

in Inflammation

Jessica Murphy
José A. Morais
Michael A. Tsoukas
Alexandra B. Cooke
Stella S. Daskalopoulou
Sylvia Santosa

Frontiers in Immunology

doi 10.3389/fimmu.2025.1601847

2,934 views
1 citation

Original Research

Published on 01 Aug 2025

Composition of peripheral blood immune cell compartment in stage 5 chronic kidney disease is affected by smoking and other risk factors associated with systemic inflammatory response

in Inflammation

Ivan Zahradka
Filip Tichanek
Lucia Majercikova
Jana Duskova
Mathias Streitz
Stephan Schlickeiser
Klara Osickova
Vojtech Petr
Petra Hruba
Petra Reinke

Frontiers in Immunology

doi 10.3389/fimmu.2025.1608206

2,084 views

Original Research

Published on 01 Aug 2025

Plasma inflammatory cytokines are associated with cognitive impairment after acute minor ischemic stroke and transient ischemic attack

in Inflammation

PanPan Zhao
Meng Zhao
GuiMei Zhang
WeiJie Zhai
YongChun Wang
YanXin Shen
Li Sun

Frontiers in Immunology

doi 10.3389/fimmu.2025.1445938

3,079 views

Original Research

Published on 31 Jul 2025

R5S4TRAIL ameliorates radiation-induced pulmonary fibrosis by alleviating inflammatory responses and promoting apoptosis of fibroblasts

in Inflammation

Yaqin Zhao
Yuanfeng Wei
Wanting Hou
Xianzhou Huang
Qiaoqi Li
Cheng Yi

Frontiers in Immunology

doi 10.3389/fimmu.2025.1600776

2,424 views

Original Research

Published on 31 Jul 2025

A novel carboxamide bromodomain inhibitor attenuates osteoarthritis via epigenetic repression of NF-κB and MAPK signaling

in Inflammation

Hyemi Lee
Seong Jae Han
Subin Ok
Kwang Min Lee
Seungseok Choi
Injoo Yoon
Somang Choi
Jina Kim
Serim Ryu
Min-Hee Son

Frontiers in Immunology

doi 10.3389/fimmu.2025.1633334

3,389 views

Original Research

Published on 31 Jul 2025

Multi-omics derivation of a core gene signature for predicting therapeutic response and characterizing immune dysregulation in inflammatory bowel disease

in Inflammation

Mingming Wang
Liping Liang
Zibo Tang
Jimin Han
Lele Wu
Le Liu
Ye Chen

Frontiers in Immunology

doi 10.3389/fimmu.2025.1611598

5,842 views
3 citations

Original Research

Published on 31 Jul 2025

Differential inflammatory responses to acute exercise and ex vivo immune challenge in young and master athletes

in Inflammation

Luciele Guerra Minuzzi
Alexandre Abilio De Souza Teixeira
Caique Figueiredo
Gilson Dorneles
Anna Cláudia Castelo Branco
Bruna Spolador de Alencar Silva
Pedro L. Valenzuela
Alessandra Peres
Alejandro Lucia
Maria Notomi Sato

Frontiers in Immunology

doi 10.3389/fimmu.2025.1601405

3,747 views

Original Research

Published on 31 Jul 2025

Molecular and subcellular mechanisms of vital macrophage extracellular trap formation

in Inflammation

Yongchan Lee
Max Brenner
Monowar Aziz
Ping Wang

Frontiers in Immunology

doi 10.3389/fimmu.2025.1608428

4,869 views
3 citations

Correction

Published on 31 Jul 2025

Correction: RvE1 attenuates polymicrobial sepsis-induced cardiac dysfunction and enhances bacterial clearance

in Inflammation

Jianmin Chen
Gareth S. D. Purvis
Debora Collotta
Sura AI Zoubi
Michelle A. Sugimoto
Antonino Cacace
Lukas Martin
Roman A. Colas
Massimo Collino
Jesmond Dalli

Frontiers in Immunology

doi 10.3389/fimmu.2025.1659224

1,399 views

Original Research

Published on 31 Jul 2025

CRIF1 gene therapy ameliorates inflammatory bowel disease by suppressing TH17 cells and fibrosis through mitochondrial function regulation

in Inflammation

Jin-Sil Park
Hye Yeon Kang
Ha Yeon Jeong
SeungCheon Yang
JeongWon Choi
Sang Hee Cho
Sol Kim
Bo-In Lee
Mi-La Cho

Frontiers in Immunology

doi 10.3389/fimmu.2025.1618012

2,739 views
1 citation

Review

Published on 30 Jul 2025

Mechanisms of copper metabolism and cuproptosis: implications for liver diseases

in Inflammation

Haoran Chen
Dongxuan Li
Huimin Zhang
Meiqi Zhang
Yumeng Lin
Haibei He
Aijun Liu
Shiming Shen
Yi Wang
Zhongyu Han

Frontiers in Immunology

doi 10.3389/fimmu.2025.1633711

7,223 views
8 citations

Original Research

Published on 29 Jul 2025

miR-223 alleviates DSS-induced colitis by prompting macrophage M2 polarization through PPAR-γ/FOXO1 signaling

in Inflammation

Juanjuan Zhang
Lixin Wang
Yingye Shen
Xiaoli Qian
Zhiming Wang
Chenyang Wang

Frontiers in Immunology

doi 10.3389/fimmu.2025.1598781

3,982 views
2 citations

Original Research

Published on 29 Jul 2025

Hypobaric hypoxia aggravates neuroinflammation in ligature-induced periodontitis mice via the STAT3 signaling pathway

in Inflammation

Lu Chen
Jiayi Zhang
Xuechao Fei
Jiajing Wang
Jiayue Gao
Xiangpei Yue
Yaqun Jiang
Zibi Shi
Shaojie Zhang
Xiufang Jiang

Frontiers in Immunology

doi 10.3389/fimmu.2025.1600035

2,721 views

Original Research

Published on 29 Jul 2025

Renal prognostic value of serum monoclonal immunoglobulin in cryoglobulinemic glomerulonephritis

in Inflammation

Lei Ma
Yuanyuan Xia
Yun Fan
Dan Zhou
Xinchen Yao
Yongzhong Zhong
Fan Yang
Feng Xu
Shaoshan Liang
Yujie Wang

Frontiers in Immunology

doi 10.3389/fimmu.2025.1578295

3,174 views

5,790 articles

articles

Extracellular vesicles in osteoarthritis: mechanisms, therapeutic potential, and diagnostic applications

The role of TGF-β superfamily in endometriosis: a systematic review

Oxidative stress and inflammation: roles in osteoporosis

Pregnancy exacerbates neutrophil responses in murine lungs and alters gut microbiota composition after cigarette smoke exposure

Single-cell multi-omics-based immune temporal network resolution in sepsis: unravelling molecular mechanisms and precise therapeutic targets

Therapeutic potential of formononetin in cirrhotic portal hypertension: modulating hepatic fibrosis, macrophage polarization, and lymphangiogenesis

Alveolar epithelial cells in bacterial sepsis-associated acute lung injury: mechanisms and therapeutic strategies

MiRNA-loaded MSC exosomes restore autophagy flux for acute pancreatitis therapy

Case Report: Low pressure hyperbaric oxygen therapy as a potential alternative treatment for chronic inflammatory response syndrome: a case study with notable improvements in fatigue, cognition, and testing

miR-210 promotes the anti-inflammatory phenotype and M2 polarization in murine macrophages

The age of obesity onset affects changes in subcutaneous adipose tissue macrophages and T cells after weight loss

Composition of peripheral blood immune cell compartment in stage 5 chronic kidney disease is affected by smoking and other risk factors associated with systemic inflammatory response

Plasma inflammatory cytokines are associated with cognitive impairment after acute minor ischemic stroke and transient ischemic attack

R5S4TRAIL ameliorates radiation-induced pulmonary fibrosis by alleviating inflammatory responses and promoting apoptosis of fibroblasts

A novel carboxamide bromodomain inhibitor attenuates osteoarthritis via epigenetic repression of NF-κB and MAPK signaling

Multi-omics derivation of a core gene signature for predicting therapeutic response and characterizing immune dysregulation in inflammatory bowel disease

Differential inflammatory responses to acute exercise and ex vivo immune challenge in young and master athletes

Molecular and subcellular mechanisms of vital macrophage extracellular trap formation

Correction: RvE1 attenuates polymicrobial sepsis-induced cardiac dysfunction and enhances bacterial clearance

CRIF1 gene therapy ameliorates inflammatory bowel disease by suppressing TH17 cells and fibrosis through mitochondrial function regulation

Mechanisms of copper metabolism and cuproptosis: implications for liver diseases

miR-223 alleviates DSS-induced colitis by prompting macrophage M2 polarization through PPAR-γ/FOXO1 signaling

Hypobaric hypoxia aggravates neuroinflammation in ligature-induced periodontitis mice via the STAT3 signaling pathway

Renal prognostic value of serum monoclonal immunoglobulin in cryoglobulinemic glomerulonephritis