Frontiers in Immunology

Original Research

Published on 19 Jun 2025

Predicting biomarkers of progressive pulmonary fibrosis: morphological, cytokine profile, and clinical portrait

in Inflammation

Nicol Bernardinello
Federica Pezzuto
Lauren D’Sa
Luca Vedovelli
Chiara Giraudo
Anamaria Chelu
Cecilia de Chellis
Francesca Lunardi
Francesco Fortarezza
Francesca Boscaro

Frontiers in Immunology

doi 10.3389/fimmu.2025.1514439

2,002 views

Original Research

Published on 19 Jun 2025

Hs-CRP/HDL-C ratio as a predictive inflammatory-lipid marker for sarcopenia: evidence from NHANES 2015–2018

in Inflammation

Xin-Yan Guo
Liang-Wen Li

Frontiers in Immunology

doi 10.3389/fimmu.2025.1600421

2,212 views

Mini Review

Published on 19 Jun 2025

A systems immunology perspective on gout pathogenesis and its precision-targeted treatment strategies

in Inflammation

Zilong Chen
Qian Guo
Yanzhao Zhang
Lulu Chen
Puyu Li
Wenfei Cheng
Chuanxin Liu
Hongwei Jiang

Frontiers in Immunology

doi 10.3389/fimmu.2025.1615914

2,226 views

Original Research

Published on 19 Jun 2025

The fibrin-derived peptide FX06 protects human pulmonary endothelial cells against the COVID-19-triggered cytokine storm

in Inflammation

Zhiran Wang
Dmitrii Lebedev
Simeng Li
Sudharshan Rao
Kevin Wu
Lorcan Doyle
Kieran Wynne
Alfonso Blanco
Margaritha M. Mysior
Jeremy C. Simpson

Frontiers in Immunology

doi 10.3389/fimmu.2025.1591860

1,703 views

Original Research

Published on 19 Jun 2025

A novel, rapid, and practical prognostic model for sepsis patients based on dysregulated immune cell lactylation

in Inflammation

Chang Li
Mei He
PeiChi Shi
Lu Yao
XiangZhi Fang
XueFeng Li
QiLan Li
XiaoBo Yang
JiQian Xu
You Shang

Frontiers in Immunology

doi 10.3389/fimmu.2025.1625311

2,036 views

Review

Published on 19 Jun 2025

Thromboinflammation vs. immunothrombosis: strategies for overcoming anticoagulant resistance in COVID-19 and other hyperinflammatory diseases. Is ROTEM helpful or not?

in Inflammation

Lou M. Almskog
Anna Ågren

Frontiers in Immunology

doi 10.3389/fimmu.2025.1599639

1,906 views

Original Research

Published on 19 Jun 2025

Single-cell atlas of human skin implicates APOE pro-inflammatory signaling in diabetic foot ulcers

in Inflammation

Yating Yin
Li Li
Mingen Liu
Bin Wang

Frontiers in Immunology

doi 10.3389/fimmu.2025.1591944

1,610 views

Mini Review

Published on 18 Jun 2025

Harnessing extracellular vesicles to tame inflammation: a new strategy for atherosclerosis therapy

in Inflammation

Jiawei Li
Tianliang Wen
Xiaoran Li
Ruoyao Cheng
Junyi Shen
Xin Wang
Zhaoqi Guo
Zhengjie Teng
Lin Yi
Fan Zhang

Frontiers in Immunology

doi 10.3389/fimmu.2025.1625958

2,085 views

Hypothesis and Theory

Published on 18 Jun 2025

Interplay of trauma-triggered auto-inflammation and T-cell auto-reactivity in posttraumatic dystrophy

in Inflammation

Egmont Scola

Frontiers in Immunology

doi 10.3389/fimmu.2025.1404161

1,012 views

Case Report

Published on 18 Jun 2025

Complete recovery after complement factor I deficiency associated fulminant acute hemorrhagic leukoencephalitis: a case report

in Inflammation

Fanni Szumutku
Léna Szabó
Zoltán Liptai
Edit Varga
Tímea Seszták
Péter Barsi
Ádám Goschler
Gábor Szarvas
Klára Horváth
Simon Péter Nagy

Frontiers in Immunology

doi 10.3389/fimmu.2025.1586288

1,406 views

Mini Review

Published on 18 Jun 2025

Decoding neuroinflammation in Alzheimer’s disease: a multi-omics and AI-driven perspective for precision medicine

in Inflammation

Shiyu Lin
Yijun Zhan
Ruiqi Wang
Jian Pei

Frontiers in Immunology

doi 10.3389/fimmu.2025.1616899

2,382 views

Review

Published on 18 Jun 2025

Revisiting pulmonary fibrosis: inflammatory dynamics of the lipofibroblast-to-inflammatory lipofibroblast-to-activated myofibroblast reversible switch

in Inflammation

Georgios-Dimitrios Panagiotidis
Esmeralda Vasquez-Pacheco
Xuran Chu
Werner Seeger
Elie El Agha
Saverio Bellusci
Arun Lingampally

Frontiers in Immunology

doi 10.3389/fimmu.2025.1609509

2,400 views

Mini Review

Published on 18 Jun 2025

Role of macrophages in neuroimmune regulation

in Inflammation

Hairong Xiao
Kai Yang

Frontiers in Immunology

doi 10.3389/fimmu.2025.1573174

1,741 views

Original Research

Published on 18 Jun 2025

Modulation of glucocorticoid receptor function under iron overload

in Inflammation

Wanting Zhu
Tineke Vanderhaeghen
Steven Timmermans
Jolien Vandewalle
Melanie Eggermont
Nicolette J. D. Verhoog
Claude Libert

Frontiers in Immunology

doi 10.3389/fimmu.2025.1605420

1,129 views

Original Research

Published on 18 Jun 2025

Short-term exposure to a high-humidity environment triggers intestinal inflammation via AQP3

in Inflammation

Jian Song
Xinhua Huang
Yi Luo
Mengjun Li
Yulin Ouyang
Wanli Liu
Hudan Pan
Huanhuan Luo

Frontiers in Immunology

doi 10.3389/fimmu.2025.1563602

1,241 views

Original Research

Published on 17 Jun 2025

Phleum pratense pollen-derived di-galactosyldiacylglycerols promote pro-allergic responses in mice

in Inflammation

Nestor González Roldán
Lars P. Lunding
Yukari Fujimoto
Sylvia Düpow
Dominik Schwudke
Michael Wegmann
Katarzyna A. Duda

Frontiers in Immunology

doi 10.3389/fimmu.2025.1532773

1,663 views