Impact Factor 4.716 | CiteScore 4.71
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Inflammation plays a fundamental role in nearly all chronic degenerative diseases and the contribution of pro-inflammatory cytokines in neurodegenerative, cardiovascular and bone diseases has become a major area of investigation. Lessons from cytokine biology are at the core of understanding inflammation. Blocking a cytokine with a “biological” outside the cell continues to be highly effective in treating several diseases and without organ toxicity. Several post-receptor signaling kinases are located downstream from cytokine-activated cells, which have become new targets to tame inflammation. Orally active small molecule inhibitors of intracellular signaling kinases will likely be the new frontier of anti-inflammatory agents.
The scope of the section Inflammation will be broad and include clinically relevant areas of investigation which apply to the following areas:
- Pro-inflammatory cytokines;
- The effects of innate inflammation;
- How inflammation affects the immune system;
- Cell signaling during inflammation.
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Inflammation welcomes submissions of the following article types: Case Report, Classification, Clinical Trial, Correction, Editorial, General Commentary, Hypothesis and Theory, Methods, Mini Review, Opinion, Original Research, Perspective, Review, Systematic Review and Technology and Code.
All manuscripts must be submitted directly to the section Inflammation, where they are peer-reviewed by the Associate and Review Editors of the specialty section.
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