Frontiers in Immunology | Parasite Immunology

Original Research

Published on 09 Jun 2025

Dual roles of Anisakis pegreffii proteins in macrophage immune dynamics

in Parasite Immunology

Min-hao Zeng
Sarah Alsobaie
Xiao-xu Wang
Shan Li
Fahad M. Aldakheel
Mourad A. M. Aboul-Soud
Wei-bin Liu

Frontiers in Immunology

doi 10.3389/fimmu.2025.1595093

2,577 views
2 citations

General Commentary

Published on 09 Jun 2025

Commentary: Induction of hepatic fibrosis in mice with schistosomiasis by extracellular microRNA-30 derived from Schistosoma japonicum eggs

in Parasite Immunology

Haoran Zhong
Yamei Jin

Frontiers in Immunology

doi 10.3389/fimmu.2025.1604905

1,920 views

Case Report

Published on 05 Jun 2025

Case Report: Disseminated leishmaniasis and rheumatoid arthritis: navigating a clinical conundrum

in Parasite Immunology

Endrit Shahini
Donatello Marziliano
Francesco Losito
Marianna Zappimbulso
Elisabetta Cavalcanti
Raffaele Armentano
Fabio Fucilli
Raffaele Cozzolongo
Giuseppe Ingravallo
Fabrizio Pappagallo

Frontiers in Immunology

doi 10.3389/fimmu.2025.1599381

4,062 views
1 citation

Original Research

Published on 27 May 2025

Emu-miR-10a-5p in Echinococcus multilocularis-derived-extracellular vesicles alleviates airway inflammation in mice with allergic asthma by inhibiting macrophage M2a polarization through LIF-mediated JAK1–STAT3 signaling

in Parasite Immunology

Yunzhuo Xin
Rou Wen
Dong Song
Jing Xiao
Xiaoping Gao
Mei Yin
Yanli Bai
Jie Wang
Xiangyu Zhou
Jiaqing Zhao

Frontiers in Immunology

doi 10.3389/fimmu.2025.1577349

4,066 views
2 citations

Original Research

Published on 20 May 2025

Integration of hepatic lipidomics and transcriptomics reveals dysregulation of lipid metabolism in a golden hamster model of visceral leishmaniasis

in Parasite Immunology

Dongmei Yuan
Hanxiao Qin
Zeying Yu

Frontiers in Immunology

doi 10.3389/fimmu.2025.1595702

3,232 views
2 citations

Editorial

Published on 08 May 2025

Editorial: Neutrophil extracellular traps (NETs) triggered by helminths and protozoan parasites

in Parasite Immunology

Rafael M. Mariante
Tamara Muñoz-Caro
Elvira M. Saraiva

Frontiers in Immunology

doi 10.3389/fimmu.2025.1613886

2,560 views
1 citation

Original Research

Published on 05 May 2025

Self and parasite-derived peptides selected upon DERAA-bearing HLA-DRB1 alleles activate CD4+ T cells from Chagas cardiomyopathy patients and are associated with ventricular dysfunction

in Parasite Immunology

Thaiany G. Souza-Silva
Eula G. A. Neves
Andrea Teixeira-Carvalho
Amanda Braga Figueiredo
Katia Luciano Pereira Morais
Juliana Apostólico
Hélcio Rodrigues
Jorge Kalil
Maria Aparecida Juliano
Luiz Juliano

Frontiers in Immunology

doi 10.3389/fimmu.2025.1527115

3,125 views
1 citation

Original Research

Published on 05 May 2025

Blue light-emitting diode phototherapy presents in vitro efficacy against distinct Leishmania species and is therapeutic against tegumentary leishmaniasis in BALB/c mice

in Parasite Immunology

Breno Luiz Pimenta
Daniela Pagliara Lage
Camila Simões de Freitas
Danniele Luciana Vale
Karolina Oliveira de Melo Falcão
Saulo Samuel Gonçalves Dias
Raquel Soares Bandeira Câmara
Isabela Amorim Gonçalves Pereira
Ana Luiza Silva
Lauro de Assis Duarte Júnior

Frontiers in Immunology

doi 10.3389/fimmu.2025.1554051

2,962 views
1 citation

Original Research

Published on 05 May 2025

Protective effects of Nippostrongylus brasiliensis-derived uridine via the apical sodium-dependent bile acid transporter in a mouse model of TNBS-induced inflammatory bowel disease

in Parasite Immunology

Caiyi Yuan
Qiang Wang
Yuying Chen
Xin Ding
Qiang Zhang
Jiakai Yao
Bei Zhang
Yang Dai
Hongxia Bai

Frontiers in Immunology

doi 10.3389/fimmu.2025.1600838

3,362 views

Original Research

Published on 01 May 2025

Spleen and peripheral blood immunopathology in an outbred model of adult-stage murine schistosomiasis

in Parasite Immunology

Thomas T. Schulze
Andrew J. Neville
Evie G. Ehrhorn
Sarah A. Alsuleiman
Jonathan L. Vennerstrom
Paul H. Davis

Frontiers in Immunology

doi 10.3389/fimmu.2025.1527129

2,767 views

Original Research

Published on 28 Apr 2025

Different responses involving Tfh cells delay parasite-specific antibody production in Trypanosoma cruzi acute experimental models

in Parasite Immunology

Ana Carolina Leão
Maria Jose Villar
Rakesh Adhikari
Cristina Poveda
Leroy Versteeg
Gregório Almeida
Peter J. Hotez
Maria Elena Bottazzi
Kathryn M. Jones

Frontiers in Immunology

doi 10.3389/fimmu.2025.1487317

3,261 views
2 citations

Original Research

Published on 17 Apr 2025

Krameria lappacea roots extract to rescue coccidiosis-mediated inflammation in the jejunum of C57BL/6 mice

in Parasite Immunology

Rewaida Abdel-Gaber
Ghada Alamari
Mohamed A. Dkhil
Saeed El-Ashram
Nawal Al-Hoshani
Esam M. Al-Shaebi
Saleh Al-Quraishy

Frontiers in Immunology

doi 10.3389/fimmu.2025.1557235

2,643 views
1 citation

Review

Published on 14 Apr 2025

Helminth-induced immune modulation in colorectal cancer: exploring therapeutic applications

in Parasite Immunology

Hongyu Li
Chaojun Shan
Yunhuan Zhu
Xiaodong Yao
Lijun Lin
Xiaofen Zhang
Yuncheng Qian
Yuqing Wang
Jialu Xu
Yijie Zhang

Frontiers in Immunology

doi 10.3389/fimmu.2025.1484686

6,531 views
6 citations

Original Research

Published on 03 Apr 2025

Characteristics and immunoprotective functions of three cysteine proteases from Clonorchis sinensis

in Parasite Immunology

Yunliang Shi
Xiaoqin Li
Kai Liang
Ting Lu
Yu Chen
Yashi Lai
Yaoting Li
Shuai Wei
Shanshan He
Lili Tang

Frontiers in Immunology

doi 10.3389/fimmu.2025.1550775

2,587 views
2 citations

Review

Published on 27 Mar 2025

Ticks’ tricks: immunomodulatory effects of ixodid tick saliva at the cutaneous tick-host interface

in Parasite Immunology

Lisa Kleissl
Sophie Weninger
Florian Winkler
Margarida Ruivo
Michiel Wijnveld
Johanna Strobl

Frontiers in Immunology

doi 10.3389/fimmu.2025.1520665

7,028 views
4 citations

Original Research

Published on 27 Mar 2025

A secreted helminth microRNA suppresses gastrointestinal cell differentiation required for innate immunity

in Parasite Immunology

Matias G. Perez
Victoria Gillan
William M. Anderson
François Gerbe
Fabien Herbert
Tom N. McNeilly
Rick M. Maizels
Philippe Jay
Eileen Devaney
Collette Britton

Frontiers in Immunology

doi 10.3389/fimmu.2025.1558132

4,304 views
9 citations

Original Research

Published on 25 Mar 2025

Plasmodium falciparum reticulocyte-binding homologues are targets of human inhibitory antibodies and play a role in immune evasion

in Parasite Immunology

Linda Reiling
Kristina E. M. Persson
Fiona J. McCallum
Nimmo Gicheru
Samson M. Kinyanjui
Chetan E. Chitnis
Freya J. I. Fowkes
Kevin Marsh
James G. Beeson

Frontiers in Immunology

doi 10.3389/fimmu.2025.1532451

3,330 views

Original Research

Published on 24 Mar 2025

Glucocorticoid receptor inhibits Th2 immune responses by down-regulating Pparg and Gata3 in schistosomiasis

in Parasite Immunology

Tao Sun
Xiaojuan Bi
Ning Yang
Xue Zhang
Jin Chu
Liang Li
Hui Liu
Rui Tang
Renyong Lin

Frontiers in Immunology

doi 10.3389/fimmu.2025.1518586

2,938 views
1 citation

Original Research

Published on 21 Mar 2025

HIF-α signaling regulates the macrophage inflammatory response during Leishmania major infection

in Parasite Immunology

Lucy G. Fry
Charity L. Washam
Hayden Roys
Anne K. Bowlin
Gopinath Venugopal
Jordan T. Bird
Stephanie D. Byrum
Tiffany Weinkopff

Frontiers in Immunology

doi 10.3389/fimmu.2025.1487311

3,283 views
1 citation

Review

Published on 12 Mar 2025

Insights to the HIV-associated visceral leishmaniasis clinical outcome: lessons learned about immune mediated disorders

in Parasite Immunology

Maria Luciana Silva-Freitas
Gabriela Corrêa-Castro
Alda Maria Da-Cruz
Joanna Reis Santos-Oliveira

Frontiers in Immunology

doi 10.3389/fimmu.2025.1516176

3,264 views
1 citation

Original Research

Published on 07 Mar 2025

Profile of soluble cell adhesion molecules as potential biomarkers in the cardiac stages of chronic Chagas disease

in Parasite Immunology

Victor Vaitkevicius-Antão
Bruno Almeida Silva
Michelle da Silva Barros
Cíntia Nascimento da Costa-Oliveira
Byannca de Carvalho Torreão
Ana Carla da Silva
Silvia Marinho Martins
Cristina Carrazone
Wilson Oliveira
Carolina de Araújo Medeiros

Frontiers in Immunology

doi 10.3389/fimmu.2025.1541860

2,319 views
2 citations

Original Research

Published on 28 Feb 2025

Reduced plasma levels of GM-CSF is a common feature of Schistosoma mansoni-infected school-aged children

in Parasite Immunology

Severin Donald Kamdem
Leonel Meyo Kamguia
Alim Oumarou
Bernard Marie Zambo Bitye
Katie Lennard
Frank Brombacher
Thomas Spangenberg
Claudia Demarta-Gatsi
Justin Komguep Nono

Frontiers in Immunology

doi 10.3389/fimmu.2025.1474575

2,709 views
1 citation

Original Research

Published on 28 Feb 2025

Liver-draining portal lymph node responds to enteric nematode infection by generating highly parasite-specific follicular T helper and B cell responses

in Parasite Immunology

Joshua Adjah
Zaneta D. Musimbi
Robert M. Mugo
Ankur Midha
Susanne Hartmann
Sebastian Rausch

Frontiers in Immunology

doi 10.3389/fimmu.2025.1483274

2,938 views
1 citation

Original Research

Published on 28 Feb 2025

Identification and validation of protective glycoproteins in Haemonchus contortus H11

in Parasite Immunology

Hui Liu
Yao Zhang
Jiarui Li
Feng Liu
Lisha Ye
Xin Liu
Chunqun Wang
Min Hu

Frontiers in Immunology

doi 10.3389/fimmu.2025.1521022

3,224 views
5 citations

456 articles

articles

Dual roles of Anisakis pegreffii proteins in macrophage immune dynamics

Commentary: Induction of hepatic fibrosis in mice with schistosomiasis by extracellular microRNA-30 derived from Schistosoma japonicum eggs

Case Report: Disseminated leishmaniasis and rheumatoid arthritis: navigating a clinical conundrum

Emu-miR-10a-5p in Echinococcus multilocularis-derived-extracellular vesicles alleviates airway inflammation in mice with allergic asthma by inhibiting macrophage M2a polarization through LIF-mediated JAK1–STAT3 signaling

Integration of hepatic lipidomics and transcriptomics reveals dysregulation of lipid metabolism in a golden hamster model of visceral leishmaniasis

Editorial: Neutrophil extracellular traps (NETs) triggered by helminths and protozoan parasites

Self and parasite-derived peptides selected upon DERAA-bearing HLA-DRB1 alleles activate CD4+ T cells from Chagas cardiomyopathy patients and are associated with ventricular dysfunction

Blue light-emitting diode phototherapy presents in vitro efficacy against distinct Leishmania species and is therapeutic against tegumentary leishmaniasis in BALB/c mice

Protective effects of Nippostrongylus brasiliensis-derived uridine via the apical sodium-dependent bile acid transporter in a mouse model of TNBS-induced inflammatory bowel disease

Spleen and peripheral blood immunopathology in an outbred model of adult-stage murine schistosomiasis

Different responses involving Tfh cells delay parasite-specific antibody production in Trypanosoma cruzi acute experimental models

Krameria lappacea roots extract to rescue coccidiosis-mediated inflammation in the jejunum of C57BL/6 mice

Helminth-induced immune modulation in colorectal cancer: exploring therapeutic applications

Characteristics and immunoprotective functions of three cysteine proteases from Clonorchis sinensis

Ticks’ tricks: immunomodulatory effects of ixodid tick saliva at the cutaneous tick-host interface

A secreted helminth microRNA suppresses gastrointestinal cell differentiation required for innate immunity

Plasmodium falciparum reticulocyte-binding homologues are targets of human inhibitory antibodies and play a role in immune evasion

Glucocorticoid receptor inhibits Th2 immune responses by down-regulating Pparg and Gata3 in schistosomiasis

HIF-α signaling regulates the macrophage inflammatory response during Leishmania major infection

Insights to the HIV-associated visceral leishmaniasis clinical outcome: lessons learned about immune mediated disorders

Profile of soluble cell adhesion molecules as potential biomarkers in the cardiac stages of chronic Chagas disease

Reduced plasma levels of GM-CSF is a common feature of Schistosoma mansoni-infected school-aged children

Liver-draining portal lymph node responds to enteric nematode infection by generating highly parasite-specific follicular T helper and B cell responses

Identification and validation of protective glycoproteins in Haemonchus contortus H11