Frontiers in Immunology | Vaccines and Molecular Therapeutics

Original Research

Accepted on 10 Oct 2025

Construction of a prognostic model based on palmitoylation-related lncRNAs for assessing drug benefits in breast cancer

in Vaccines and Molecular Therapeutics

Yan Wang
Mengsi Zhang
Yuqin Zhou
Zaozhuo Li
Xinglin Yi
Lin Ren
Yi Zhang

Frontiers in Immunology

doi 10.3389/fimmu.2025.1656593

Original Research

Accepted on 10 Oct 2025

Exploring ceRNA Mechanisms in COVID-19 mRNA Vaccine-Induced Myocarditis: Implications for Future Vaccine Design

in Vaccines and Molecular Therapeutics

Xi-yuan Ge
Jing Wang
Xin-Yi Sun
Qian Gao
Min Fu
Mian Xiao
Ning Du

Frontiers in Immunology

doi 10.3389/fimmu.2025.1674049

120 views

Review

Published on 10 Oct 2025

Monoclonal antibodies against influenza viruses: a clinical trials review

in Vaccines and Molecular Therapeutics

Kenneth Gabriel Mota
Ana Maria Moro

Frontiers in Immunology

doi 10.3389/fimmu.2025.1669073

440 views

Original Research

Published on 10 Oct 2025

A biomimetic model composed of injectable 3D muscle-like tissue, stromal and immune cells for recapitulating the rapid immune signature predictive of mRNA vaccine immunogenicity

in Vaccines and Molecular Therapeutics

Marilena Paola Etna
Claudia Fuoco
Martina Severa
Daniela Ricci
Alessandro Sinigaglia
Camilla Lucca
Giada Cairo
Barbara Bottazzi
Cecilia Garlanda
Anna Teresa Palamara

Frontiers in Immunology

doi 10.3389/fimmu.2025.1651095

528 views

Original Research

Published on 10 Oct 2025

Nasal vaccination against Trypanosoma cruzi: a dual approach for prevention and treatment of chronic Chagas cardiomyopathy

in Vaccines and Molecular Therapeutics

Paula Cacik
Maria Florencia Pacini
Camila Bulfoni Balbi
Brenda Dinatale
Genaro Diaz
Ulises Cha
Cecilia Farré
Mónica Gianeselli
Estefanía Prochetto
Ana Rosa Peréz

Frontiers in Immunology

doi 10.3389/fimmu.2025.1662036

477 views

Review

Published on 10 Oct 2025

MAPPs assays for non-clinical immunogenicity risk assessment: best practices recommended by the European immunogenicity platform

in Vaccines and Molecular Therapeutics

A.C. Karle
K. L. Kopp
R.J. Seward
S. Tourdot
C. Ackaert
M. Gutknecht
E. Cloake
N. Smith
A. Ducret

Frontiers in Immunology

doi 10.3389/fimmu.2025.1690101

582 views

Original Research

Accepted on 09 Oct 2025

rBCG-LTAK63 Enhances Protection Against Tuberculosis by Inducing Autophagy and Circadian Gene Regulation

in Vaccines and Molecular Therapeutics

Lázaro Moreira Marques-Neto
Monalisa Martins Trentini
Ana Carolina Ramos Moreno
Silas F. Eto
Ana Carolina de Oliveira Carvalho
Almiro Neto
Murilo Sena Amaral
André Guilherme Costa-Martins
André Nicolau Aquime Gonçalves
Ana Marisa ana.tavassi@butantan.gov.br

Frontiers in Immunology

doi 10.3389/fimmu.2025.1695560

125 views

Original Research

Accepted on 09 Oct 2025

Exogenous Melatonin Boosts Vaccine-Induced Immunity in Individuals with High Pre-Existing Influenza Immunity

in Vaccines and Molecular Therapeutics

Kyosuke Oda
Janine Danko
Eileen Villasante
Elke Bergmann-Leitner
Rachel Lee
Wathsala Wijayalath

Frontiers in Immunology

doi 10.3389/fimmu.2025.1663763

126 views

Clinical Trial

Accepted on 08 Oct 2025

Safety, Tolerability, and Immunogenicity of INO-4500, a Synthetic DNA-based Vaccine against Lassa Virus (LASV), in a Phase 1b Clinical Trial in Healthy Ghanaian Adults

in Vaccines and Molecular Therapeutics

Kwadwo Ansah Koram
Kathleen A Walker
Bonaventure Orizu
Idania Marrero
Jean Boyer
ShuPing Yang
Kate E Broderick
Kwadwo Asamoah Kusi
Eric Kyei-Baafour
EBENEZER ADDO OFORI

Frontiers in Immunology

doi 10.3389/fimmu.2025.1658549

175 views

Original Research

Published on 08 Oct 2025

Immunoadjuvanted influenza vaccine immunogenicity in children with type 1 diabetes over two consecutive seasons

in Vaccines and Molecular Therapeutics

Mikhail Petrovich Kostinov
Maria Alexandrovna Kvasova
Alla Anatolievna Tarasova
Anna Vlasenko
Elena Vladimirovna Kolbasina
Darya Alexandrovna Bydanova
Aristitsa Kostinova
Valentina Polishchuk
Isabella Abramovna Khrapunova
Marina Loktionova

Frontiers in Immunology

doi 10.3389/fimmu.2025.1597619

616 views

Review

Published on 08 Oct 2025

Insights into tumor vaccines for elderly individuals in the context of immunosenescence

in Vaccines and Molecular Therapeutics

Chenglong Li
Zhujun Chen
Changyu Zhu
Min Chen
Jinqi Li
Lei Zhong
Yingying Hou

Frontiers in Immunology

doi 10.3389/fimmu.2025.1660874

1,255 views

Original Research

Accepted on 07 Oct 2025

Promiscuous class II-binding SARS-CoV-2-nuc derived vaccine-peptide induced extensive conventional, innate and unconventional T cell responses

in Vaccines and Molecular Therapeutics

Karin Schilbach
Naomi Krickeberg
Hans-Georg --- Rammensee

Frontiers in Immunology

doi 10.3389/fimmu.2025.1676455

219 views

Review

Accepted on 07 Oct 2025

Different antibody isotypes against tuberculosis: what we know and what we need to know

in Vaccines and Molecular Therapeutics

Huoming Li
Hao Li

Frontiers in Immunology

doi 10.3389/fimmu.2025.1682934

Original Research

Accepted on 07 Oct 2025

An oral M-cell targeted Lactococcus lactis vaccine against Echinococcus multilocularis infection

in Vaccines and Molecular Therapeutics

Feng Tang
Yang Xiao
Runle Li

Frontiers in Immunology

doi 10.3389/fimmu.2025.1683003

Original Research

Published on 07 Oct 2025

Subcutaneous administration of the malaria R21/Matrix M vaccine and immune complex formation with anti-circumsporozoite protein mAb 2A10 elicit protective efficacy in mice

in Vaccines and Molecular Therapeutics

Ekta Mukhopadhyay
César López Camacho
Adrian V. S. Hill
Ahmed M. Salman

Frontiers in Immunology

doi 10.3389/fimmu.2025.1675780

775 views

Original Research

Published on 07 Oct 2025

Machine learning insights into vaccine adjuvants and immune outcomes

in Vaccines and Molecular Therapeutics

Yuhyun Ji
Kavitha Bekkari
Ruchin Patel
Mohammed Shardar
Geoffrey A. Walford
SamMoon Kim
Yaping Liu
Willis Read-Button
Kristina Tracy
Jennifer Kriss

Frontiers in Immunology

doi 10.3389/fimmu.2025.1654060

1,341 views