Frontiers in Molecular Biosciences

Original Research

Published on 15 Oct 2024

Identification of potential bioactive phytochemicals for the inhibition of platelet-derived growth factor receptor β: a structure-based approach for cancer therapy

in Structural Biology

Insan Habib
Md Nayab Sulaimani
Deeba Shamim Jairajpuri
Afzal Hussain
Taj Mohammad
Mohamed F. Alajmi
Anas Shamsi
Md Imtaiyaz Hassan

Frontiers in Molecular Biosciences

doi 10.3389/fmolb.2024.1492847

3,378 views
8 citations

Original Research

Published on 03 Oct 2024

Shedding light on the DICER1 mutational spectrum of uncertain significance in malignant neoplasms

in Structural Biology

D. S. Bug
I. S. Moiseev
Yu. B. Porozov
N. V. Petukhova

Frontiers in Molecular Biosciences

doi 10.3389/fmolb.2024.1441180

3,117 views
3 citations

Original Research

Published on 01 Oct 2024

Semantic segmentation-based detection algorithm for challenging cryo-electron microscopy RNP samples

in Structural Biology

J. Vargas
A. Modrego
H. Canabal
J. Martin-Benito

Frontiers in Molecular Biosciences

doi 10.3389/fmolb.2024.1473609

2,137 views
1 citation

Original Research

Published on 27 Sep 2024

Structure features of Streptococcus pneumoniae FabG and virtual screening of allosteric inhibitors

in Structural Biology

Kaimin Xu
Jianliang Zhong
Jing Li
Yulu Cao
Lai Wei

Frontiers in Molecular Biosciences

doi 10.3389/fmolb.2024.1472252

6,071 views

Brief Research Report

Published on 17 Sep 2024

Structural bases for blockade and activation of BK channels by Ba2+ ions

in Structural Biology

Shubhra Srivastava
Pablo Miranda
Teresa Giraldez
Jianghai Zhu
Raul E. Cachau
Miguel Holmgren

Frontiers in Molecular Biosciences

doi 10.3389/fmolb.2024.1454273

2,424 views
1 citation

Editorial

Published on 02 Sep 2024

Editorial: New approaches toward understanding challenges in molecular virology: computational techniques and machine learning

in Structural Biology

Srirupa Chakraborty
Kun Qu
Jayaraman Valadi

Frontiers in Molecular Biosciences

doi 10.3389/fmolb.2024.1472796

2,169 views
2 citations

Editorial

Published on 26 Aug 2024

Editorial: Prediction of protein-protein interactions (PPIs): the next frontier

in Structural Biology

Amar Singh
Binh P. Nguyen
Ho Leung Ng

Frontiers in Molecular Biosciences

doi 10.3389/fmolb.2024.1479705

2,190 views

Original Research

Published on 30 Jul 2024

Candidate proteins interacting with cytoskeleton in cells from the basal airway epithelium in vitro

in Structural Biology

Olusola A. Olatona
Sayantan R. Choudhury
Ray Kresman
Carol A. Heckman

Frontiers in Molecular Biosciences

doi 10.3389/fmolb.2024.1423503

3,681 views
2 citations

Review

Published on 30 Jul 2024

AlphaFold2 in biomedical research: facilitating the development of diagnostic strategies for disease

in Structural Biology

Hong Zhang
Jiajing Lan
Huijie Wang
Ruijie Lu
Nanqi Zhang
Xiaobai He
Jun Yang
Linjie Chen

Frontiers in Molecular Biosciences

doi 10.3389/fmolb.2024.1414916

10,115 views
11 citations

Review

Published on 24 Jul 2024

Cryo-electron microscopy in the study of virus entry and infection

in Structural Biology

Moumita Dutta
Priyamvada Acharya

Frontiers in Molecular Biosciences

doi 10.3389/fmolb.2024.1429180

10,184 views
9 citations

Editorial

Published on 19 Jul 2024

Editorial: When predictions meet experiments: the future of structure determination

in Structural Biology

Caterina Alfano

Frontiers in Molecular Biosciences

doi 10.3389/fmolb.2024.1446746

1,608 views

Original Research

Published on 09 Jul 2024

Towards interpretable Cryo-EM: disentangling latent spaces of molecular conformations

in Structural Biology

David A. Klindt
Aapo Hyvärinen
Axel Levy
Nina Miolane
Frédéric Poitevin

Frontiers in Molecular Biosciences

doi 10.3389/fmolb.2024.1393564

4,242 views
7 citations

Original Research

Published on 21 Jun 2024

A pangenome analysis of ESKAPE bacteriophages: the underrepresentation may impact machine learning models

in Structural Biology

Jeesu Lee
Branden Hunter
Hyunjin Shim

Frontiers in Molecular Biosciences

doi 10.3389/fmolb.2024.1395450

3,196 views
9 citations

Original Research

Published on 06 Jun 2024

Are there double knots in proteins? Prediction and in vitro verification based on TrmD-Tm1570 fusion from C. nitroreducens

in Structural Biology

Agata P. Perlinska
Mai Lan Nguyen
Smita P. Pilla
Emilia Staszor
Iwona Lewandowska
Agata Bernat
Elżbieta Purta
Rafal Augustyniak
Janusz M. Bujnicki
Joanna I. Sulkowska

Frontiers in Molecular Biosciences

doi 10.3389/fmolb.2023.1223830

3,994 views
7 citations

Review

Published on 29 May 2024

The advent of preventive high-resolution structural histopathology by artificial-intelligence-powered cryogenic electron tomography

in Structural Biology

Jesús G. Galaz-Montoya

Frontiers in Molecular Biosciences

doi 10.3389/fmolb.2024.1390858

4,383 views
5 citations

Original Research

Published on 22 May 2024

DiffraGAN: a conditional generative adversarial network for phasing single molecule diffraction data to atomic resolution

in Structural Biology

S. Matinyan
P. Filipcik
E. van Genderen
J. P. Abrahams

Frontiers in Molecular Biosciences

doi 10.3389/fmolb.2024.1386963

2,249 views

Original Research

Published on 30 Apr 2024

Dynamics and thermal stability of the bypass polymerase, DinB homolog (Dbh)

in Structural Biology

Jenaro Soto
Sean L. Moro
Melanie J. Cocco

Frontiers in Molecular Biosciences

doi 10.3389/fmolb.2024.1364068

2,295 views
1 citation

Perspective

Published on 18 Apr 2024

Machine learning approaches to cryoEM density modification differentially affect biomacromolecule and ligand density quality

in Structural Biology

Raymond F. Berkeley
Brian D. Cook
Mark A. Herzik

Frontiers in Molecular Biosciences

doi 10.3389/fmolb.2024.1404885

4,121 views
13 citations

Original Research

Published on 18 Apr 2024

Implication of Stm1 in the protection of eIF5A, eEF2 and tRNA through dormant ribosomes

in Structural Biology

Mengtan Du
Xin Li
Wanlin Dong
Fuxing Zeng

Frontiers in Molecular Biosciences

doi 10.3389/fmolb.2024.1395220

4,581 views
9 citations

Editorial

Published on 28 Mar 2024

Editorial: Functions, working mechanisms, and regulation of rotary ATPases and Ductin proteins

in Structural Biology

Tibor Páli
Boris Feniouk
Stephan Wilkens

Frontiers in Molecular Biosciences

doi 10.3389/fmolb.2024.1399421

2,484 views
1 citation

Hypothesis and Theory

Published on 28 Mar 2024

The coordinated activities of collagen VI and XII in maintenance of tissue structure, function and repair: evidence for a physical interaction

in Structural Biology

Carl A. Gregory
Jocelyn Ma
Sebastian Lomeli

Frontiers in Molecular Biosciences

doi 10.3389/fmolb.2024.1376091

6,843 views
11 citations

Perspective

Published on 22 Mar 2024

Simple Scattering: Lipid nanoparticle structural data repository

in Structural Biology

Lee Joon Kim
David Shin
Wellington C. Leite
Hugh O’Neill
Oliver Ruebel
Andrew Tritt
Greg L. Hura

Frontiers in Molecular Biosciences

doi 10.3389/fmolb.2024.1321364

4,536 views
4 citations

Original Research

Published on 19 Mar 2024

Eukaryotic yeast V1-ATPase rotary mechanism insights revealed by high-resolution single-molecule studies

in Structural Biology

Seiga Yanagisawa
Zain A. Bukhari
Karlett J. Parra
Wayne D. Frasch

Frontiers in Molecular Biosciences

doi 10.3389/fmolb.2024.1269040

2,530 views
4 citations

Original Research

Published on 15 Mar 2024

Membrane-assisted tariquidar access and binding mechanisms of human ATP-binding cassette transporter P-glycoprotein

in Structural Biology

Yingjie Gao
Caiyan Wei
Lanxin Luo
Yang Tang
Yongzhen Yu
Yaling Li
Juan Xing
Xianchao Pan

Frontiers in Molecular Biosciences

doi 10.3389/fmolb.2024.1364494

3,725 views
12 citations

500 articles

articles

Identification of potential bioactive phytochemicals for the inhibition of platelet-derived growth factor receptor β: a structure-based approach for cancer therapy

Shedding light on the DICER1 mutational spectrum of uncertain significance in malignant neoplasms

Semantic segmentation-based detection algorithm for challenging cryo-electron microscopy RNP samples

Structure features of Streptococcus pneumoniae FabG and virtual screening of allosteric inhibitors

Structural bases for blockade and activation of BK channels by Ba2+ ions

Editorial: New approaches toward understanding challenges in molecular virology: computational techniques and machine learning

Editorial: Prediction of protein-protein interactions (PPIs): the next frontier

Candidate proteins interacting with cytoskeleton in cells from the basal airway epithelium in vitro

AlphaFold2 in biomedical research: facilitating the development of diagnostic strategies for disease

Cryo-electron microscopy in the study of virus entry and infection

Editorial: When predictions meet experiments: the future of structure determination

Towards interpretable Cryo-EM: disentangling latent spaces of molecular conformations

A pangenome analysis of ESKAPE bacteriophages: the underrepresentation may impact machine learning models

Are there double knots in proteins? Prediction and in vitro verification based on TrmD-Tm1570 fusion from C. nitroreducens

The advent of preventive high-resolution structural histopathology by artificial-intelligence-powered cryogenic electron tomography

DiffraGAN: a conditional generative adversarial network for phasing single molecule diffraction data to atomic resolution

Dynamics and thermal stability of the bypass polymerase, DinB homolog (Dbh)

Machine learning approaches to cryoEM density modification differentially affect biomacromolecule and ligand density quality

Implication of Stm1 in the protection of eIF5A, eEF2 and tRNA through dormant ribosomes

Editorial: Functions, working mechanisms, and regulation of rotary ATPases and Ductin proteins

The coordinated activities of collagen VI and XII in maintenance of tissue structure, function and repair: evidence for a physical interaction

Simple Scattering: Lipid nanoparticle structural data repository

Eukaryotic yeast V1-ATPase rotary mechanism insights revealed by high-resolution single-molecule studies

Membrane-assisted tariquidar access and binding mechanisms of human ATP-binding cassette transporter P-glycoprotein