Frontiers in Molecular Neuroscience

Review

Published on 23 Jul 2025

Decoding chronic pain: the glutamate-GABA tug of war in the cerebral cortex

in Pain Mechanisms and Modulators

Dan Huang
Yu-Ting Dong
Liu-Xuan He
Rui-Zhu Zhou
Jian-Xiong Zhou
Sha Yang
Shu-Guang Yu

Frontiers in Molecular Neuroscience

doi 10.3389/fnmol.2025.1572775

4,075 views
1 citation

Review

Published on 21 Jul 2025

Calcium signaling in postsynaptic mitochondria: mechanisms, dynamics, and role in ATP production

in Molecular Signalling and Pathways

Tatiana Feofilaktova
Liliia Kushnireva
Menahem Segal
Eduard Korkotian

Frontiers in Molecular Neuroscience

doi 10.3389/fnmol.2025.1621070

5,357 views
5 citations

Original Research

Published on 17 Jul 2025

Tet3-mediated DNA demethylation is essential for maintaining the dedifferentiation capacity of mammalian Müller glia

in Molecular Signalling and Pathways

Erick J. Martinez-Colin
Ivonne Lezama
Lenin D. Ochoa-de la Paz
Monica Lamas

Frontiers in Molecular Neuroscience

doi 10.3389/fnmol.2025.1628860

2,646 views
3 citations

Original Research

Published on 14 Jul 2025

Inhibition of BET proteins modulates amyloid-beta accumulation and cognitive performance in middle-aged mice prenatally exposed to maternal immune activation

in Brain Disease Mechanisms

Marta Matuszewska
Anna Wilkaniec
Magdalena Gąssowska-Dobrowolska
Magdalena Cieślik
Gabriela Olech-Kochańczyk
Ewelina Pałasz
Elżbieta Gawinek
Marcin Strawski
Grzegorz A. Czapski

Frontiers in Molecular Neuroscience

doi 10.3389/fnmol.2025.1619583

2,481 views
1 citation

Original Research

Published on 08 Jul 2025

Peripheral gene dysregulation in Negr1-deficient mice: insights into possible links with affective behavior

in Molecular Signalling and Pathways

Abdulkadir Yusif Maigoro
Jangrae Kim
Seoyeon Cho
Ara Yoo
Soojin Lee

Frontiers in Molecular Neuroscience

doi 10.3389/fnmol.2025.1602201

3,194 views
1 citation

Review

Published on 07 Jul 2025

Role of the chaperonin TCP-1 ring complex in protein aggregation and neurodegeneration

in Brain Disease Mechanisms

Vanlalrinchhani Varte
Diego E. Rincon-Limas

Frontiers in Molecular Neuroscience

doi 10.3389/fnmol.2025.1617771

3,574 views
3 citations

Review

Published on 04 Jul 2025

Exosome-mediated miRNA delivery: a molecular switch for reshaping neuropathic pain therapy

in Pain Mechanisms and Modulators

Ziqing Wei
Chunhui Guo
Hang Zhou
Yanling Wu
Xudong Zhou
Jibing Chen
Fujun Li

Frontiers in Molecular Neuroscience

doi 10.3389/fnmol.2025.1625943

5,432 views
10 citations

Review

Published on 04 Jul 2025

TRP channels in mammalian hearing loss

in Molecular Signalling and Pathways

Zhidong Zhang
Baoshan Wang

Frontiers in Molecular Neuroscience

doi 10.3389/fnmol.2025.1626640

2,090 views

Review

Published on 02 Jul 2025

The neurological pathology of peroxisomal ACBD5 deficiency – lessons from patients and mouse models

in Molecular Signalling and Pathways

Michael L. Dawes
Jim P. Haberlander
Markus Islinger
Michael Schrader

Frontiers in Molecular Neuroscience

doi 10.3389/fnmol.2025.1602343

3,371 views
4 citations

Systematic Review

Published on 02 Jul 2025

Recognition of the microbial metabolite p-cresol in autism spectrum disorder: systematic review and meta-analysis

in Brain Disease Mechanisms

María Isabel Serrano-Tomás
Paulina Contreras-Romero
Mara Parellada
Javier Chaves-Cordero
Javier Zamora
Martha Hengst
Patricia Pozo
Rosa del Campo
Sheyla Guzmán-Salas

Frontiers in Molecular Neuroscience

doi 10.3389/fnmol.2025.1576388

3,455 views
3 citations

Editorial

Published on 01 Jul 2025

Editorial: Come as you R(NA): post-transcriptional regulation will do the rest

in Neuroplasticity and Development

Oriane Mauger
Michael A. Kiebler
Clémence Bernard

Frontiers in Molecular Neuroscience

doi 10.3389/fnmol.2025.1644067

2,629 views

Review

Published on 26 Jun 2025

Decoding pain chronification: mechanisms of the acute-to-chronic transition

in Pain Mechanisms and Modulators

Shunwei Zhang
Youzhi Ning
Yiyi Yang
Guo Mu
Yongkui Yang
Changhe Ren
Changli Liao
Cehua Ou
Yue Zhang

Frontiers in Molecular Neuroscience

doi 10.3389/fnmol.2025.1596367

9,207 views
11 citations

Original Research

Published on 26 Jun 2025

Research hotspots and emerging trends in MicroRNA therapy for neuropathic pain: a bibliometric analysis (2009–2024)

in Pain Mechanisms and Modulators

Yiqiang Zhang
Shushu Chen
Jiangtao Chi
Qinghua Gao
Yujie Li
Huaizhao Wang
Yuanyuan Yu

Frontiers in Molecular Neuroscience

doi 10.3389/fnmol.2025.1610844

2,064 views

Review

Published on 26 Jun 2025

Mechanism of heme oxygenase-1 regulation of ferroptosis in vascular dementia

in Brain Disease Mechanisms

Xin-yi Zou
Luo-yang Cai
Jin Zhang
Ying Yuan
Jie Song
Zhao-duan Hu
Xiao-feng Ruan
Rui Peng
Xiao-ming Zhang

Frontiers in Molecular Neuroscience

doi 10.3389/fnmol.2025.1585079

3,591 views
7 citations

Original Research

Published on 26 Jun 2025

The potential anti-seizure effects of Astaxanthin-loaded nanostructured lipid carriers in rat model of status epilepticus

in Molecular Signalling and Pathways

Sherien E. Khalaf
Mohammad Al Masri
Ghaleb Oriquat
Maher A. Kamel
Nagwa M. Assem
Suzan M. Abdel-Tawab
Samar S. Elblehi
Shimaa A. Mahmoud

Frontiers in Molecular Neuroscience

doi 10.3389/fnmol.2025.1613893

2,800 views
1 citation

Original Research

Published on 25 Jun 2025

Critical gene network and signaling pathway analysis of the extracellular signal-regulated kinase (ERK) pathway in ischemic stroke

in Brain Disease Mechanisms

Rui Mao
Lei Wang
Haitao Zhang
Jiaojiao Gong
Hua Liu

Frontiers in Molecular Neuroscience

doi 10.3389/fnmol.2025.1604670

2,345 views

Review

Published on 25 Jun 2025

How endothelial cell metabolism shapes blood–brain barrier integrity in neurodegeneration

in Brain Disease Mechanisms

Jiaxin Wang
Yuchun Chen
Shiteng Chen
Zihan Mu
Jun Chen

Frontiers in Molecular Neuroscience

doi 10.3389/fnmol.2025.1623321

3,945 views
4 citations

Original Research

Published on 25 Jun 2025

Whole-genome sequencing shows modulation of neurodegenerative genes by Withania somnifera in human SK-N-SH cells

in Brain Disease Mechanisms

Eshita Sharma
Dilip Mehta
Nikita Jadhav
Gunjan Gujrati
S. Dhananya
Manju Moorthy
Gopalakrishna Ramaswamy
Yundong Zhou
Sujit Nair

Frontiers in Molecular Neuroscience

doi 10.3389/fnmol.2025.1512727

4,273 views
1 citation

Original Research

Published on 23 Jun 2025

Exploring research trends and hotspots in PI3K/Akt signaling pathway in ischemic stroke: a bibliometric analysis

in Molecular Signalling and Pathways

Yingquan Liu
Yu Ye
Lin Bai
Fan Dai
Xingxing Su
Peijia Hu
Hongliang Cheng

Frontiers in Molecular Neuroscience

doi 10.3389/fnmol.2025.1613702

3,268 views
2 citations

Original Research

Published on 20 Jun 2025

Silencing ATF3 mediates mitochondrial homeostasis and improves ischemic stroke through regulating the MAPK signaling pathway

in Molecular Signalling and Pathways

Haifengqing Li
Fan Zhang
Cong Zhang
Min Zhou
Qing Liu
Guoyong Zeng

Frontiers in Molecular Neuroscience

doi 10.3389/fnmol.2025.1554802

2,589 views

Review

Published on 20 Jun 2025

Peroxisome dynamics and inter-organelle interactions in neuronal health and disease

in Molecular Signalling and Pathways

Ruth E. Carmichael

Frontiers in Molecular Neuroscience

doi 10.3389/fnmol.2025.1603632

5,019 views

Original Research

Published on 19 Jun 2025

Dysregulation of heterochromatin caused by genomic structural variants may be central to autism spectrum disorder

in Molecular Signalling and Pathways

Michael R. Garvin
David Kainer

Frontiers in Molecular Neuroscience

doi 10.3389/fnmol.2025.1553575

2,653 views
1 citation

Original Research

Published on 18 Jun 2025

Clusterin facilitates glioma progression via BCL2L1-dependent regulation of apoptotic resistance

in Brain Disease Mechanisms

Qingqing Xu
Xin Liu
Yibo Zhang
Shiyu Yuan
Wenli Huang
Mingshan Pi
Qi Xiong
Hongyan Zhou
Yuran Gui
Yifan Xiao

Frontiers in Molecular Neuroscience

doi 10.3389/fnmol.2025.1596021

2,217 views
1 citation

Brief Research Report

Published on 18 Jun 2025

Inhibition of class IIa HDACs reduces mutant HTT aggregation by affecting RNA stability

in Molecular Signalling and Pathways

Annika Reisbitzer
Cecilia Hollitzer
Adriana Geraci
Jessye Schaefer
Maximilian Burghaus
Jonas Bruns
Joachim Urban
Thomas Kurz
Sybille Krauß

Frontiers in Molecular Neuroscience

doi 10.3389/fnmol.2025.1579194

2,482 views
1 citation

4,350 articles

articles

Decoding chronic pain: the glutamate-GABA tug of war in the cerebral cortex

Calcium signaling in postsynaptic mitochondria: mechanisms, dynamics, and role in ATP production

Tet3-mediated DNA demethylation is essential for maintaining the dedifferentiation capacity of mammalian Müller glia

Inhibition of BET proteins modulates amyloid-beta accumulation and cognitive performance in middle-aged mice prenatally exposed to maternal immune activation

Peripheral gene dysregulation in Negr1-deficient mice: insights into possible links with affective behavior

Role of the chaperonin TCP-1 ring complex in protein aggregation and neurodegeneration

Exosome-mediated miRNA delivery: a molecular switch for reshaping neuropathic pain therapy

TRP channels in mammalian hearing loss

The neurological pathology of peroxisomal ACBD5 deficiency – lessons from patients and mouse models

Recognition of the microbial metabolite p-cresol in autism spectrum disorder: systematic review and meta-analysis

Editorial: Come as you R(NA): post-transcriptional regulation will do the rest

Decoding pain chronification: mechanisms of the acute-to-chronic transition

Research hotspots and emerging trends in MicroRNA therapy for neuropathic pain: a bibliometric analysis (2009–2024)

Mechanism of heme oxygenase-1 regulation of ferroptosis in vascular dementia

The potential anti-seizure effects of Astaxanthin-loaded nanostructured lipid carriers in rat model of status epilepticus

Critical gene network and signaling pathway analysis of the extracellular signal-regulated kinase (ERK) pathway in ischemic stroke

How endothelial cell metabolism shapes blood–brain barrier integrity in neurodegeneration

Whole-genome sequencing shows modulation of neurodegenerative genes by Withania somnifera in human SK-N-SH cells

Exploring research trends and hotspots in PI3K/Akt signaling pathway in ischemic stroke: a bibliometric analysis

Silencing ATF3 mediates mitochondrial homeostasis and improves ischemic stroke through regulating the MAPK signaling pathway

Peroxisome dynamics and inter-organelle interactions in neuronal health and disease

Dysregulation of heterochromatin caused by genomic structural variants may be central to autism spectrum disorder

Clusterin facilitates glioma progression via BCL2L1-dependent regulation of apoptotic resistance

Inhibition of class IIa HDACs reduces mutant HTT aggregation by affecting RNA stability