DynTransNet: Dynamic Transformer Network with Multi-Scale Attention for Liver Cancer Segmentation

Siming Zheng^1,2A S M Sharifuzzaman Sagar³Yu Chen⁴Zehao Yu²Shi Ying⁵Yongyi Zeng^1,6*

• ¹First Affiliated Hospital of Fujian Medical University, Fuzhou, Fujian Province, China
• ²Department of Hepatopancreatobiliary Surgery, First Hospital of Ningbo University, Ningbo, China
• ³Sejong University, Seoul, Seoul, Republic of Korea
• ⁴MetaSyntec Co., LTD, George Town, Cayman Islands
• ⁵Ningbo Wedge Medical Technology Co., LTD, Ningbo, China
• ⁶Department of Hepatopancreatobiliary Surgery, Mengchao Hepatobiliary Hospital of Fujian Medical University, Fuzhou, China

Hepatocellular carcinoma (HCC), a predominant subtype of liver cancer, remains a major contributor to global cancer mortality. Accurate delineation of liver tumors in CT and MRI scans is critical for treatment planning and clinical decision-making. However, manual segmentation is time-consuming, error-prone, and inconsistent, necessitating reliable automated approaches. This study presents a novel U-shaped segmentation framework inspired by U-Net, designed to enhance accuracy and robustness. The encoder incorporates Dynamic Multi-Head Self-Attention (D-MSA) to capture both global and local spatial dependencies, while the decoder uses skip connections to preserve spatial detail. Additionally, a Feature Mix Module (FM-M) blends multi-scale features, and a Residual Module (RM) refines feature representations and stabilizes training. The proposed framework addresses key challenges such as boundary precision, complex structural relationships, and dataset imbalance. Experimental results demonstrate superior segmentation performance, achieving a mean Dice score of 86.12 on the ATLAS dataset and 93.12 on the LiTS dataset. The proposed method offers a robust, efficient tool for liver tumor segmentation and holds strong potential to streamline diagnostic workflows and improve automated medical image analysis in clinical practice.