Frontiers in Oncology | Cancer Genetics

Original Research

Published on 27 May 2025

GNG7 as a tumor-suppressor gene in lung adenocarcinoma: implications for prognosis and immune-based therapies

in Cancer Genetics

Kexin Luo
Meihan Liu
Zhongqin Peng
Haiyang Zhao
Guoyi Li
Yuanze Cai
Yumeng Lei
Hongpan Zhang
Yongsheng Zhao

Frontiers in Oncology

doi 10.3389/fonc.2025.1588646

153 views

Original Research

Published on 26 May 2025

Promoter hypermethylation of SFRP1 is an allele fraction-dependent prognostic biomarker in metastatic pancreatic ductal adenocarcinoma

in Cancer Genetics

Benjamin Stubbe
Malene P. Stoico
Simone K. Terp
Poul H. Madsen
Søren Lundbye-Christensen
Carsten P. Hansen
Laurids Ø. Poulsen
Louise S. Rasmussen
Mette N. Yilmaz
Lars H. Jensen

Frontiers in Oncology

doi 10.3389/fonc.2025.1568386

250 views

Original Research

Published on 21 May 2025

Early-stage endometrioid carcinoma with MSH6 protein deficiency: pitfalls in the diagnostic interpretation of microsatellite instability

in Cancer Genetics

Cheng Wang
Dongni Liang
Wei Wang
Wei Kuang
Juan Zou
Jing Zeng
Min Feng

Frontiers in Oncology

doi 10.3389/fonc.2025.1520500

343 views

Case Report

Accepted on 20 May 2025

Primary pancreas NTRK-rearranged neoplasm harboring an EVT6::NTRK3 fusion with a sclerosing epithelioid fibrosarcoma morphology: a case report and comprehensive review of the literature

in Cancer Genetics

Xin Wu
Dujian Li
Fangfang Fu
Lifei Lian

Frontiers in Oncology

doi 10.3389/fonc.2025.1526281

111 views

Review

Accepted on 20 May 2025

The Role of MYEOV Gene: A Review and Future Directions

in Cancer Genetics

Yidan Xi
Yanan Ge
Mingzhe Jiang
Dong Zhao
Ershu Zhao
Fei Cai
Xinlong Wang
Jiatong Li
Xuefei Liu
Tingting Li

Frontiers in Oncology

doi 10.3389/fonc.2025.1543590

Original Research

Published on 19 May 2025

Identification of novel prognostic biomarkers for thyroid cancer by integrated transcriptome analysis of metastasis-associated genes

in Cancer Genetics

Bushra Alnwisser
Salman Alshehri
Amal Qattan
Minjing Zou
Abdelilah Aboussekhra
Ali S. Alzahrani
Yufei Shi

Frontiers in Oncology

doi 10.3389/fonc.2025.1536270

504 views

Original Research

Published on 19 May 2025

Integrating next-generation sequencing and artificial intelligence for the identification and validation of pathogenic variants in colorectal cancer

in Cancer Genetics

Juliana Rodriguez-Salamanca
Mariana Angulo-Aguado
Sarah Orjuela-Amarillo
Catalina Duque
Diana Carolina Sierra-Díaz
Nora Contreras Bravo
Carlos Figueroa
Carlos M. Restrepo
Andrés López-Cortés
Rodrigo Cabrera

Frontiers in Oncology

doi 10.3389/fonc.2025.1568205

601 views

Original Research

Accepted on 15 May 2025

EPHX2 Overexpression Deters the Advancement of Clear Cell Renal Cell Carcinoma via Lipid Metabolism Reprogramming

in Cancer Genetics

Bo Guan
Cong Huang
Jun He
Weimin Shan
Di Cui
Xiaowei Li
Chaozhao Liang
Zongyao Hao

Frontiers in Oncology

doi 10.3389/fonc.2025.1541429

157 views

Review

Accepted on 13 May 2025

The Regulatory Network of Epithelial-Mesenchymal Transition-Associated Non-Coding RNAs in Thyroid Cancer: Molecular Mechanisms, Clinical Implications, and Therapeutic Strategies

in Cancer Genetics

Rui Zhao
Jiaju Tian
Jing Peng
Ruiting Ma
Songbo Fu

Frontiers in Oncology

doi 10.3389/fonc.2025.1592467

Case Report

Published on 13 May 2025

Case Report: Retroperitoneal dedifferentiated solitary fibrous tumor with unexpected Pax-2 expression, mimicking high grade clear cell renal cell carcinoma

in Cancer Genetics

Jia Wei
Chen-chen Yao
Yue-Fen Zou
Yong-Zhong Wei
Qin-he Fan
Qi-xing Gong

Frontiers in Oncology

doi 10.3389/fonc.2025.1569160

285 views

Perspective

Accepted on 12 May 2025

Personalized Preventive Medicine Using Genomic Information: Future Perspective and Corresponding Research Plan

in Cancer Genetics

Hiroto Narimatsu
Kaname Watanabe
Ann Sato
Eri Haneda
Masumi Okamoto
Haruka Nakada
Sho Nakamura

Frontiers in Oncology

doi 10.3389/fonc.2025.1599753

144 views

Original Research

Accepted on 09 May 2025

Leaf-Vein-Inspired Multi-Organ Microfluidic Chip for Modeling Breast Cancer CTC Organotropism

in Cancer Genetics

Liuyin Liu
Xiaoli Qu
Zhe Wang
Cheng Ji
Ling Rui
Changjiao Yan

Frontiers in Oncology

doi 10.3389/fonc.2025.1602225

Case Report

Accepted on 08 May 2025

Case Report: Biallelic BRCA1 Pathogenic Alterations in a Fanconi Anemia Patient and Clinical Implications of Variant Location

in Cancer Genetics

Colin Young
Ashley Lahr
Caroline Nestor
Ashley Kaminski
Marcy Richardson
Georgianne L Arnold

Frontiers in Oncology

doi 10.3389/fonc.2025.1572310

Case Report

Accepted on 08 May 2025

Influence of BRCA1 germline mutation on treatment-related morbidity of a non-seminomatous germ cell tumor patient

in Cancer Genetics

Bruno Griesler
Susann Schulze
Thomas Kegel
Christine Dierks
Pablo Villavicencio-Lorini
Markus Eszlinger
Haifa Al-Ali
Nadja Jäkel

Frontiers in Oncology

doi 10.3389/fonc.2025.1579574

Original Research

Accepted on 08 May 2025

Genomic profiles and prognostic biomarkers of resectable lung adenocarcinoma with a micropapillary component

in Cancer Genetics

Jiafu Zhu
Sun Xinhai
JiangShan Huang
Wenwei Lin
Yanyan Zhan
Junrong Yan
Yang Xu
Long Wu
Yuane Lian
Zhenyang Zhang

Frontiers in Oncology

doi 10.3389/fonc.2025.1574817

Original Research

Published on 08 May 2025

Revisiting the molecular landscape of Rosai-Dorfman disease: insights from whole exome sequencing of Saudi patients

in Cancer Genetics

Sarah Binhassan
Manar Samman
Yazeed Al-Sheikh
Wafaa Alshakweer
Tahani Alhalouli
Najd Alshamlan
Manal Abudawood

Frontiers in Oncology

doi 10.3389/fonc.2025.1556830

680 views