Frontiers in Oncology | Cancer Genetics

Original Research

Accepted on 11 Jun 2025

TLR4/MyD88 Expression Patterns and Novel Genetic Variants: Association with Aggressive Clinicopathological Features in Colorectal Cancer

in Cancer Genetics

Tra Thai Dang
Nhat Viet Pham
Dung Ngoc Tran
Hang Thu Ngo
Mao Van Can
Hoang Huy Nguyen
Xuan Thi Nguyen
Chung Thanh Dang

Frontiers in Oncology

doi 10.3389/fonc.2025.1568729

Perspective

Published on 09 Jun 2025

Personalized preventive medicine using genomic information: future perspective and corresponding research plan

in Cancer Genetics

Hiroto Narimatsu
Kaname Watanabe
Ann Sato
Eri Haneda
Masumi Okamoto
Haruka Nakada
Sho Nakamura

Frontiers in Oncology

doi 10.3389/fonc.2025.1599753

592 views

Case Report

Published on 06 Jun 2025

Primary pancreas NTRK-rearranged neoplasm harboring an EVT6::NTRK3 fusion with a sclerosing epithelioid fibrosarcoma morphology: a case report and comprehensive review of the literature

in Cancer Genetics

Xin Wu
Dujuan Li
Fangfang Fu
Lifei Lian

Frontiers in Oncology

doi 10.3389/fonc.2025.1526281

785 views

Original Research

Accepted on 05 Jun 2025

SPP1+ Tumor-Associated Macrophages Define a High-Risk Subgroup and Inform Personalized Therapy in Hepatocellular Carcinoma

in Cancer Genetics

Wei-xuan Xu
Yamei Ye
Jia-Lin Chen
Xin-Ying Guo
Chen Li
Juan Luo
Lin-Bin Lu
Xiong Chen

Frontiers in Oncology

doi 10.3389/fonc.2025.1606195

107 views

Original Research

Published on 05 Jun 2025

EPHX2 overexpression deters the advancement of clear cell renal cell carcinoma via lipid metabolism reprogramming

in Cancer Genetics

Bo Guan
Cong Huang
Jun He
Weimin Shan
Di Cui
Xiaowei Li
Chaozhao Liang
Zongyao Hao

Frontiers in Oncology

doi 10.3389/fonc.2025.1541429

496 views

Review

Published on 04 Jun 2025

The role of MYEOV gene: a review and future directions

in Cancer Genetics

Yidan Xi
Xuefei Liu
Yanan Ge
Mingzhe Jiang
Dong Zhao
Ershu Zhao
Fei Cai
Xinlong Wang
Jiatong Li
Tingting Li

Frontiers in Oncology

doi 10.3389/fonc.2025.1543590

343 views

Original Research

Accepted on 03 Jun 2025

Deciphering the Impact of Intra-tumoral Bacterial Infiltration on Multi-omics Profiles in Low-Grade Gliomas

in Cancer Genetics

Wenshu Li
Zixiang Zhu
Longyuan Li
Xin Wu
Jiaxuan Li
Yi Zhou
Lingwen Gu
Pranathi Vittal
Zhouqing Chen
Zhong Wang

Frontiers in Oncology

doi 10.3389/fonc.2025.1582068

102 views

Review

Published on 02 Jun 2025

The regulatory network of epithelial-mesenchymal transition-associated non-coding RNAs in thyroid cancer: molecular mechanisms, clinical implications, and therapeutic strategies

in Cancer Genetics

Rui Zhao
Jiaju Tian
Jing Peng
Ruiting Ma
Songbo Fu

Frontiers in Oncology

doi 10.3389/fonc.2025.1592467

579 views

Case Report

Published on 30 May 2025

Case Report: Biallelic BRCA1 pathogenic alterations in a Fanconi Anemia patient and clinical implications of variant location

in Cancer Genetics

Colin C. Young
Ashley Lahr
Caroline Nestor
Ashley Kaminski
Marcy E. Richardson
Georgianne L. Arnold

Frontiers in Oncology

doi 10.3389/fonc.2025.1572310

869 views

Case Report

Published on 30 May 2025

Case Report: Influence of BRCA1 germline mutation on treatment-related morbidity of a non-seminomatous germ cell tumor patient

in Cancer Genetics

Bruno Griesler
Susann Schulze
Thomas Kegel
Christine Dierks
Pablo Villavicencio-Lorini
Markus Eszlinger
Haifa Kathrin Al-Ali
Nadja Jaekel

Frontiers in Oncology

doi 10.3389/fonc.2025.1579574

414 views

Original Research

Published on 29 May 2025

Genomic profiles and prognostic biomarkers of resectable lung adenocarcinoma with a micropapillary component

in Cancer Genetics

Jiafu Zhu
Xinhai Sun
Jiangshan Huang
Wenwei Lin
Yanyan Zhan
Junrong Yan
Yang Xu
Long Wu
Yuane Lian
Zhenyang Zhang

Frontiers in Oncology

doi 10.3389/fonc.2025.1574817

489 views

Original Research

Published on 29 May 2025

Leaf-vein-inspired multi-organ microfluidic chip for modeling breast cancer CTC organotropism

in Cancer Genetics

Liuyin Liu
Xiaoli Qu
Zhe Wang
Cheng Ji
Rui Ling
Changjiao Yan

Frontiers in Oncology

doi 10.3389/fonc.2025.1602225

487 views

Original Research

Published on 27 May 2025

GNG7 as a tumor-suppressor gene in lung adenocarcinoma: implications for prognosis and immune-based therapies

in Cancer Genetics

Kexin Luo
Meihan Liu
Zhongqin Peng
Haiyang Zhao
Guoyi Li
Yuanze Cai
Yumeng Lei
Hongpan Zhang
Yongsheng Zhao

Frontiers in Oncology

doi 10.3389/fonc.2025.1588646

555 views

Original Research

Published on 26 May 2025

Promoter hypermethylation of SFRP1 is an allele fraction-dependent prognostic biomarker in metastatic pancreatic ductal adenocarcinoma

in Cancer Genetics

Benjamin Stubbe
Malene P. Stoico
Simone K. Terp
Poul H. Madsen
Søren Lundbye-Christensen
Carsten P. Hansen
Laurids Ø. Poulsen
Louise S. Rasmussen
Mette N. Yilmaz
Lars H. Jensen

Frontiers in Oncology

doi 10.3389/fonc.2025.1568386

628 views

Original Research

Published on 21 May 2025

Early-stage endometrioid carcinoma with MSH6 protein deficiency: pitfalls in the diagnostic interpretation of microsatellite instability

in Cancer Genetics

Cheng Wang
Dongni Liang
Wei Wang
Wei Kuang
Juan Zou
Jing Zeng
Min Feng

Frontiers in Oncology

doi 10.3389/fonc.2025.1520500

845 views

Original Research

Published on 19 May 2025

Integrating next-generation sequencing and artificial intelligence for the identification and validation of pathogenic variants in colorectal cancer

in Cancer Genetics

Juliana Rodriguez-Salamanca
Mariana Angulo-Aguado
Sarah Orjuela-Amarillo
Catalina Duque
Diana Carolina Sierra-Díaz
Nora Contreras Bravo
Carlos Figueroa
Carlos M. Restrepo
Andrés López-Cortés
Rodrigo Cabrera

Frontiers in Oncology

doi 10.3389/fonc.2025.1568205

5,324 views