Frontiers in Oncology | Cancer Genetics

Original Research

Published on 17 Jun 2021

Comprehensive Landscape of Ovarian Cancer Immune Microenvironment Based on Integrated Multi-Omics Analysis

in Cancer Genetics

Jiacheng Shen
Tingwei Liu
Qiaoli Bei
Shaohua Xu

Frontiers in Oncology

doi 10.3389/fonc.2021.685065

5,279 views
10 citations

Original Research

Published on 16 Jun 2021

The ETS Inhibitor YK-4-279 Suppresses Thyroid Cancer Progression Independent of TERT Promoter Mutations

in Cancer Genetics

Junyu Xue
Shiyong Li
Peijie Shi
Mengke Chen
Shuang Yu
Shubin Hong
Yanbing Li
Rengyun Liu
Haipeng Xiao

Frontiers in Oncology

doi 10.3389/fonc.2021.649323

6,163 views
11 citations

Original Research

Published on 15 Jun 2021

Regulatory Network Analysis of Mutated Genes Based on Multi-Omics Data Reveals the Exclusive Features in Tumor Immune Microenvironment Between Left-Sided and Right-Sided Colon Cancer

in Cancer Genetics

Tianfei Yi
Yuwei Zhang
Derry Minyao Ng
Yang Xi
Meng Ye
Lvjun Cen
Jianjiong Li
Xiaoxiang Fan
Yanguo Li
Shiyun Hu

Frontiers in Oncology

doi 10.3389/fonc.2021.685515

6,182 views
13 citations

Review

Published on 14 Jun 2021

Role of Exosomal Non-coding RNAs in Gastric Cancer: Biological Functions and Potential Clinical Applications

in Cancer Genetics

Feng Hu
Jixuan Liu
Huibo Liu
Fan Li
Minjie Wan
Manli Zhang
Yanfang Jiang
Min Rao

Frontiers in Oncology

doi 10.3389/fonc.2021.700168

7,372 views
9 citations

Original Research

Published on 14 Jun 2021

A Tumor Progression Related 7-Gene Signature Indicates Prognosis and Tumor Immune Characteristics of Gastric Cancer

in Cancer Genetics

Fen Liu
Zongcheng Yang
Lixin Zheng
Wei Shao
Xiujie Cui
Yue Wang
Jihui Jia
Yue Fu

Frontiers in Oncology

doi 10.3389/fonc.2021.690129

6,126 views
9 citations

Original Research

Published on 11 Jun 2021

Integrated Analysis of the Transcriptome Profile Reveals the Potential Roles Played by Long Noncoding RNAs in Immunotherapy for Sarcoma

in Cancer Genetics

Boran Pang
Yongqiang Hao

Frontiers in Oncology

doi 10.3389/fonc.2021.690486

3,411 views
8 citations

Original Research

Published on 11 Jun 2021

Prognostic Biomarkers on a Competitive Endogenous RNA Network Reveals Overall Survival in Triple-Negative Breast Cancer

in Cancer Genetics

Wenxing Qin
Feng Qi
Jia Li
Ping Li
Yuan-Sheng Zang

Frontiers in Oncology

doi 10.3389/fonc.2021.681946

5,083 views
6 citations

Original Research

Published on 11 Jun 2021

An Improved Detection of Circulating Tumor DNA in Extracellular Vesicles-Depleted Plasma

in Cancer Genetics

Li Sun
Meijun Du
Manish Kohli
Chiang-Ching Huang
Xiaoxiang Chen
Mu Xu
Hongbing Shen
Shukui Wang
Liang Wang

Frontiers in Oncology

doi 10.3389/fonc.2021.691798

6,218 views
6 citations

Original Research

Published on 11 Jun 2021

The Identification of Stemness-Related Genes in the Risk of Head and Neck Squamous Cell Carcinoma

in Cancer Genetics

Guanying Feng
Feifei Xue
Yingzheng He
Tianxiao Wang
Hua Yuan

Frontiers in Oncology

doi 10.3389/fonc.2021.688545

7,016 views
6 citations

Original Research

Published on 11 Jun 2021

Correlation Between Circulating Tumor Cell DNA Genomic Alterations and Mesenchymal CTCs or CTC-Associated White Blood Cell Clusters in Hepatocellular Carcinoma

in Cancer Genetics

Chunming Wang
Qiong Luo
Wenbin Huang
Cheng Zhang
Hangyu Liao
Kunling Chen
MingXin Pan

Frontiers in Oncology

doi 10.3389/fonc.2021.686365

5,511 views
13 citations

Original Research

Published on 11 Jun 2021

Prevalence and Spectrum of Germline BRCA1 and BRCA2 Variants of Uncertain Significance in Breast/Ovarian Cancer: Mysterious Signals From the Genome

in Cancer Genetics

Daniele Fanale
Alessia Fiorino
Lorena Incorvaia
Alessandra Dimino
Clarissa Filorizzo
Marco Bono
Daniela Cancelliere
Valentina Calò
Chiara Brando
Lidia Rita Corsini

Frontiers in Oncology

doi 10.3389/fonc.2021.682445

10,768 views
27 citations

Original Research

Published on 10 Jun 2021

LRRC3B Polymorphisms Contributed to Breast Cancer Susceptibility in Chinese Han Population

in Cancer Genetics

Yuxin Wang

Frontiers in Oncology

doi 10.3389/fonc.2021.657168

2,425 views
4 citations

Original Research

Published on 10 Jun 2021

DDX60 Is Associated With Glioma Malignancy and Serves as a Potential Immunotherapy Biomarker

in Cancer Genetics

Jingwen Zhang
Minjie Fu
Mengli Zhang
Jinsen Zhang
Zunguo Du
Hongyi Zhang
Wei Hua
Ying Mao

Frontiers in Oncology

doi 10.3389/fonc.2021.665360

7,389 views
14 citations

Methods

Published on 08 Jun 2021

DIVIS: Integrated and Customizable Pipeline for Cancer Genome Sequencing Analysis and Interpretation

in Cancer Genetics

Xiaoyu He
Yu Zhang
Danyang Yuan
Xinyin Han
Jiayin He
Xiaohong Duan
Siyao Liu
Xintong Wang
Beifang Niu

Frontiers in Oncology

doi 10.3389/fonc.2021.672597

5,226 views
3 citations

Original Research

Published on 08 Jun 2021

Single-Cell RNA-seq Identification of the Cellular Molecular Characteristics of Sporadic Bilateral Clear Cell Renal Cell Carcinoma

in Cancer Genetics

Zhenyuan Yu
Wenhao Lu
Cheng Su
Yufang Lv
Yu Ye
Bingqian Guo
Deyun Liu
Haibiao Yan
Hua Mi
Tianyu Li

Frontiers in Oncology

doi 10.3389/fonc.2021.659251

9,874 views
28 citations

Original Research

Published on 08 Jun 2021

Profiling of 520 Candidate Genes in 50 Surgically Treated Chinese Small Cell Lung Cancer Patients

in Cancer Genetics

Ting Yuan
Xin Wang
Sijin Sun
Zheng Cao
Xiaoli Feng
Yibo Gao

Frontiers in Oncology

doi 10.3389/fonc.2021.644434

6,588 views
13 citations

Review

Published on 07 Jun 2021

FDA-Approved and Emerging Next Generation Predictive Biomarkers for Immune Checkpoint Inhibitors in Cancer Patients

in Cancer Genetics

Ye Wang
Zhuang Tong
Wenhua Zhang
Weizhen Zhang
Anton Buzdin
Xiaofeng Mu
Qing Yan
Xiaowen Zhao
Hui-Hua Chang
Mark Duhon

Frontiers in Oncology

doi 10.3389/fonc.2021.683419

30,810 views
200 citations

Original Research

Published on 07 Jun 2021

WRN Germline Mutation Is the Likely Inherited Etiology of Various Cancer Types in One Iranian Family

in Cancer Genetics

Mahnaz Norouzi
Mohammad Shafiei
Zeinab Abdollahi
Paniz Miar
Hamid Galehdari
Mohammad Hasan Emami
Mehrdad Zeinalian
Mohammad Amin Tabatabaiefar

Frontiers in Oncology

doi 10.3389/fonc.2021.648649

7,202 views
6 citations

Original Research

Published on 01 Jun 2021

Silencing of the Long Non-Coding RNA TTN-AS1 Attenuates the Malignant Progression of Osteosarcoma Cells by Regulating the miR-16-1-3p/TFAP4 Axis

in Cancer Genetics

Xianghai Meng
Zhenjun Zhang
Lin Chen
Xi Wang
Qingguo Zhang
Shuheng Liu

Frontiers in Oncology

doi 10.3389/fonc.2021.652835

2,795 views
9 citations

Original Research

Published on 01 Jun 2021

Correlation Analysis Between MTHFR C677T Polymorphism and Uterine Fibroids: A Retrospective Cohort Study

in Cancer Genetics

Jiahui Shen
Yanhui Jiang
Fengzhi Wu
Hui Chen
Qiujing Wu
Xiaoxiao Zang
Le Chen
Yong Chen
Qiwen Yuan

Frontiers in Oncology

doi 10.3389/fonc.2021.648794

5,407 views
3 citations

Original Research

Published on 31 May 2021

Development and Validation of a Nomogram Based on Nutritional Indicators and Tumor Markers for Prognosis Prediction of Pancreatic Ductal Adenocarcinoma

in Cancer Genetics

Haoran Li
Fang Zhou
Zhifei Cao
Yuchen Tang
Yujie Huang
Ye Li
Bin Yi
Jian Yang
Peng Du
Dongming Zhu

Frontiers in Oncology

doi 10.3389/fonc.2021.682969

3,548 views
9 citations

Original Research

Published on 31 May 2021

CircKEAP1 Suppresses the Progression of Lung Adenocarcinoma via the miR-141-3p/KEAP1/NRF2 Axis

in Cancer Genetics

Yanbo Wang
Fenghai Ren
Dawei Sun
Jing Liu
BenKun Liu
YunLong He
Sainan Pang
BoWen Shi
FuCheng Zhou
Lei Yao

Frontiers in Oncology

doi 10.3389/fonc.2021.672586

4,315 views
23 citations

Original Research

Published on 31 May 2021

Unraveling Immune-Related lncRNAs in Breast Cancer Molecular Subtypes

in Cancer Genetics

Carolina Mathias
João Carlos Degraf Muzzi
Bruna Borba Antunes
Daniela F. Gradia
Mauro A. A. Castro
Jaqueline Carvalho de Oliveira

Frontiers in Oncology

doi 10.3389/fonc.2021.692170

8,253 views
41 citations

Original Research

Published on 28 May 2021

Comprehensive Analysis of GLUT1 Immune Infiltrates and ceRNA Network in Human Esophageal Carcinoma

in Cancer Genetics

Xu-Sheng Liu
Yan Gao
Li-Bing Wu
Hua-Bing Wan
Peng Yan
Yang Jin
Shi-Bo Guo
Ya-Lan Wang
Xue-Qin Chen
Lu-Meng Zhou

Frontiers in Oncology

doi 10.3389/fonc.2021.665388

12,320 views
28 citations

1,234 articles

articles

Comprehensive Landscape of Ovarian Cancer Immune Microenvironment Based on Integrated Multi-Omics Analysis

The ETS Inhibitor YK-4-279 Suppresses Thyroid Cancer Progression Independent of TERT Promoter Mutations

Regulatory Network Analysis of Mutated Genes Based on Multi-Omics Data Reveals the Exclusive Features in Tumor Immune Microenvironment Between Left-Sided and Right-Sided Colon Cancer

Role of Exosomal Non-coding RNAs in Gastric Cancer: Biological Functions and Potential Clinical Applications

A Tumor Progression Related 7-Gene Signature Indicates Prognosis and Tumor Immune Characteristics of Gastric Cancer

Integrated Analysis of the Transcriptome Profile Reveals the Potential Roles Played by Long Noncoding RNAs in Immunotherapy for Sarcoma

Prognostic Biomarkers on a Competitive Endogenous RNA Network Reveals Overall Survival in Triple-Negative Breast Cancer

An Improved Detection of Circulating Tumor DNA in Extracellular Vesicles-Depleted Plasma

The Identification of Stemness-Related Genes in the Risk of Head and Neck Squamous Cell Carcinoma

Correlation Between Circulating Tumor Cell DNA Genomic Alterations and Mesenchymal CTCs or CTC-Associated White Blood Cell Clusters in Hepatocellular Carcinoma

Prevalence and Spectrum of Germline BRCA1 and BRCA2 Variants of Uncertain Significance in Breast/Ovarian Cancer: Mysterious Signals From the Genome

LRRC3B Polymorphisms Contributed to Breast Cancer Susceptibility in Chinese Han Population

DDX60 Is Associated With Glioma Malignancy and Serves as a Potential Immunotherapy Biomarker

DIVIS: Integrated and Customizable Pipeline for Cancer Genome Sequencing Analysis and Interpretation

Single-Cell RNA-seq Identification of the Cellular Molecular Characteristics of Sporadic Bilateral Clear Cell Renal Cell Carcinoma

Profiling of 520 Candidate Genes in 50 Surgically Treated Chinese Small Cell Lung Cancer Patients

FDA-Approved and Emerging Next Generation Predictive Biomarkers for Immune Checkpoint Inhibitors in Cancer Patients

WRN Germline Mutation Is the Likely Inherited Etiology of Various Cancer Types in One Iranian Family

Silencing of the Long Non-Coding RNA TTN-AS1 Attenuates the Malignant Progression of Osteosarcoma Cells by Regulating the miR-16-1-3p/TFAP4 Axis

Correlation Analysis Between MTHFR C677T Polymorphism and Uterine Fibroids: A Retrospective Cohort Study

Development and Validation of a Nomogram Based on Nutritional Indicators and Tumor Markers for Prognosis Prediction of Pancreatic Ductal Adenocarcinoma

CircKEAP1 Suppresses the Progression of Lung Adenocarcinoma via the miR-141-3p/KEAP1/NRF2 Axis

Unraveling Immune-Related lncRNAs in Breast Cancer Molecular Subtypes

Comprehensive Analysis of GLUT1 Immune Infiltrates and ceRNA Network in Human Esophageal Carcinoma