Frontiers in Oncology | Cancer Molecular Targets and Therapeutics

Original Research

Published on 12 May 2025

RACGAP1 and MKI67 are potential prognostic biomarker in hepatocellular carcinoma caused by HBV/HCV via lactylation

in Cancer Molecular Targets and Therapeutics

Muhammad Muddasar Saeed
Xinying Ma
Xinyu Fu
Ikram Ullah
Tanveer Ali
Changchuan Bai
Ying Liu
Chengyong Dong
Xiaonan Cui

Frontiers in Oncology

doi 10.3389/fonc.2025.1537084

551 views

Original Research

Accepted on 09 May 2025

Deciphering the Circadian Rhythm in Colorectal Cancer: A Bibliometric Analysis of Research Landscape and Trends

in Cancer Molecular Targets and Therapeutics

Linzi Chen
Jinhui Liu
Yuhan Tao
Ningkun Xiao

Frontiers in Oncology

doi 10.3389/fonc.2025.1591257

Original Research

Published on 09 May 2025

Single-cell and spatial transcriptomics reveal correlation between RNA methylation-related miRNA risk model and immune infiltration in hepatocellular carcinoma

in Cancer Molecular Targets and Therapeutics

Rong Su
Yong Du
Pan Tian
Weifang Ma
Yongfeng Hui
Shaoqi Yang

Frontiers in Oncology

doi 10.3389/fonc.2025.1553239

650 views

Case Report

Published on 09 May 2025

Case Report: Ensartinib as a first-line treatment for SMARCA4-deficient and EML4-ALK non-small cell lung cancer

in Cancer Molecular Targets and Therapeutics

Yanqing Pan
Lingxin Yan
Shaoxi Wang
Huiling Li
Quanfang Chen

Frontiers in Oncology

doi 10.3389/fonc.2025.1530142

564 views

Original Research

Published on 09 May 2025

Uncovering key regulatory pathways and prognostic biomarkers in the tumor microenvironment of high-grade serous ovarian cancer through single-cell RNA sequencing and experimental validation

in Cancer Molecular Targets and Therapeutics

Yue Li
Long Zhao
Ying Tian
Qianqian Zhou
Xia Liu
Shucai Yang
Jinfeng Xu
Chang Zou
Jinling Zhang
Hui Luo

Frontiers in Oncology

doi 10.3389/fonc.2025.1591430

507 views

Original Research

Accepted on 08 May 2025

Multidimensional analysis suggests that ZNF433 is a promising biomarker for the diagnosis and prognosis of human cancers

in Cancer Molecular Targets and Therapeutics

Lingyu Xie
Xin Zeng
Hui Luo
Bin Xie
Xuefeng Wang
Nan Wu
Junrong Zou
Guoxi Zhang
Xiaofeng Zou
Hui Xu

Frontiers in Oncology

doi 10.3389/fonc.2025.1584042

Review

Accepted on 08 May 2025

Research Progress on NUSAP1 and Its Role in Digestive System Neoplasms

in Cancer Molecular Targets and Therapeutics

Shangui Fu
Yuting Zhuo
Tao Yu

Frontiers in Oncology

doi 10.3389/fonc.2025.1582361

Original Research

Published on 08 May 2025

Integrated analysis identifies P4HA2 as a key regulator of STAT1-mediated colorectal cancer progression and a potential biomarker for precision therapy

in Cancer Molecular Targets and Therapeutics

Qianshi Zhang
Yinan Zhang
Zhiwei Sun
Huanle Wang
Guohang Dai
Yue Meng
Shasha Shi
Shuangyi Ren

Frontiers in Oncology

doi 10.3389/fonc.2025.1581860

426 views

Review

Accepted on 07 May 2025

Unveiling the Impact of Lipid Metabolism on Triple-Negative Breast Cancer Growth and Treatment Options

in Cancer Molecular Targets and Therapeutics

Xin-Xian Cai
Zhezhong Zhang
Xiao-Xiao Yang
Wen-Rui Shen
Liu-Wei Yuan
Xi Ding
Ying Yu
Wenyu Cai

Frontiers in Oncology

doi 10.3389/fonc.2025.1579423

Original Research

Published on 06 May 2025

Correlation of heat shock protein 1 expression with progression and prognosis of non-small cell lung cancer

in Cancer Molecular Targets and Therapeutics

Rui Wang
Rongqi Guo
Tianyi Huang
Yu Lu
Weisong Zhang
Yihao Wang
Qinggan Ni
Jianxiang Song
Xia Li

Frontiers in Oncology

doi 10.3389/fonc.2025.1553248

713 views

Original Research

Accepted on 05 May 2025

Molecular and Clinical Insights into HIV-Associated and HIV-Negative Aggressive B-Cell Lymphomas: Prognostic Quantitative Biomarker Analysis and Therapeutic Implications

in Cancer Molecular Targets and Therapeutics

Liming Liu
Tianwa Wang
Jiping Luo
Jianrong Huang
Kaipeng Huang
Kun Chen
Chao Wang
Zhiqiang Cheng

Frontiers in Oncology

doi 10.3389/fonc.2025.1603801

Mini Review

Published on 05 May 2025

Downregulation of PAQR3 expression predicts poor prognosis of patients with pan-cancer: a meta-analysis

in Cancer Molecular Targets and Therapeutics

Kui Zhai
Xing-Peng Miao
Shi-Gui Ai
Qiang Guo
Ren-Zhong Zha

Frontiers in Oncology

doi 10.3389/fonc.2025.1574150

596 views

Case Report

Published on 02 May 2025

Case Report: Clinical response of ensartinib for inflammatory myofibroblastic tumor of the urinary bladder with multiple metastases and TPM4-ALK fusion

in Cancer Molecular Targets and Therapeutics

Hongtao Ren
Qi Cheng
Xi Chen
Dianjing Sui
Zhiyi Zhang
Fei Chen

Frontiers in Oncology

doi 10.3389/fonc.2025.1481602

526 views

Original Research

Published on 02 May 2025

The role of PSMC4 in non-small cell lung cancer: implications for prognosis, diagnosis, and immune microenvironment modulation

in Cancer Molecular Targets and Therapeutics

Lili Zhu
Yuanjun Li
Yunfei Xu
Jian Lei

Frontiers in Oncology

doi 10.3389/fonc.2025.1503466

687 views

Case Report

Published on 30 Apr 2025

Acquired ROS1 fusion and iruplinalkib response in advanced NSCLC after multiple lines of systematic therapy: a case report

in Cancer Molecular Targets and Therapeutics

Jiarui Liu
Zhichao Jiao
Jun Zhou
Yuan Yuan
Qiguang Li
Wei Zhou
Shuai Zhang
Shuping Yang

Frontiers in Oncology

doi 10.3389/fonc.2025.1571512

861 views

Review

Published on 30 Apr 2025

Mitochondrial ribosomal proteins: potential targets for cancer prognosis and therapy

in Cancer Molecular Targets and Therapeutics

Jianqing Zhu
Na Wen
Wen Chen
Haotian Yu

Frontiers in Oncology

doi 10.3389/fonc.2025.1586137

723 views