Frontiers in Oncology | Molecular and Cellular Oncology

Original Research

Published on 06 Nov 2025

PPP2CA knockdown upregulates the expression levels of ferroptosis-related genes TFRC and ACSL4 in colorectal cancer cells by promoting mTOR phosphorylation

in Molecular and Cellular Oncology

Jing Cheng
Zhihan Liu
Haibo Liu
Chao Fang
Jun Li

Frontiers in Oncology

doi 10.3389/fonc.2025.1694932

266 views

Review

Accepted on 05 Nov 2025

Deciphering Molecular Pathways Driving Cancer Invasion and Metastasis: Advances and Therapeutic Prospects

in Molecular and Cellular Oncology

Aziza Alshahrani
Arwa Al-subait
Zahrah Asiri
Sahar Saleh Alghamdi
Sarah Bin Saqyah
Tariq Alqahtani
Njoud Altuwaijri
Rawan Fitaihi
Yahya F. Jamous

Frontiers in Oncology

129 views

Original Research

Accepted on 03 Nov 2025

Integrative Modeling of FOXO-Mediated Autophagy in NSCLC: Linking cGAS-STING Signaling to IL-6 Dynamics

in Molecular and Cellular Oncology

Divya Rani
Shweta Khandibharad
Shailza Singh

Frontiers in Oncology

156 views

General Commentary

Accepted on 31 Oct 2025

ABLIM1: A novel oncogenic E3 ligase in colorectal cancer

in Molecular and Cellular Oncology

Sehbanul Islam
Ganesh Barik
Osheen Sahay

Frontiers in Oncology

217 views

Original Research

Accepted on 31 Oct 2025

BAG3 in human tumors

in Molecular and Cellular Oncology

Paola Manzo
Anna Lisa Cammarota
Jelena Dimitrov
Alessandra Rosati
Liberato Marzullo
Maria Caterina Turco
Vincenzo De Laurenzi
Gianluca Sala
Margot De Marco
Anna Basile

Frontiers in Oncology

Brief Research Report

Accepted on 30 Oct 2025

Persistently high prevalence of HPV16 and Rising Prevalence of Non-16/18 HR-HPV Genotypes in Cervical Precancer and Cancer in Latvia in 2016-2024 Shape the Severity of Cervical Disease

in Molecular and Cellular Oncology

Liba Sokolovska
Karina Biserova
Arta Spridzane
Daira Krisane
Alesja Dudorova
Svetlana Gebrila
Ilvija Krasovska
Dmitry Perminov
Beatrise Orlova
Marta Petrovska

Frontiers in Oncology

Review

Accepted on 29 Oct 2025

Post-translational modifications of protein and lung cancer

in Molecular and Cellular Oncology

Ying Zhao
Xiaoyu Song
Wenfeng Luo
Mei fang Xie
Jian Shen
Jin-hua He
Ze-ping Han
Jin-ju Huang

Frontiers in Oncology

146 views

Original Research

Published on 28 Oct 2025

Temporal dynamics of cisplatin-induced endothelial senescence and its association with cognitive impairment: insights into the medial prefrontal cortex

in Molecular and Cellular Oncology

Yue Hei
Sheng-nan Kong
Juan-hua Sun
Wei-ping Liu
Qian-fa Long
Hong-mei Zhang

Frontiers in Oncology

doi 10.3389/fonc.2025.1668372

505 views

Original Research

Accepted on 27 Oct 2025

FGF21 inhibits invasion and metastasis via IL-17A-Notch in pancreatic ductal adenocarcinoma

in Molecular and Cellular Oncology

Fangdan Li
Panchun Zheng
Xiongwu Li
Yaying Yang
Hangyu Zhou
Linjun Li

Frontiers in Oncology

116 views

Original Research

Published on 27 Oct 2025

An early-stage 3D fibroblast-featured tumor model mimics the gene expression of the naïve tumor microenvironment, including genes involved in cancer progression and drug resistance

in Molecular and Cellular Oncology

Francesca Costabile
Subin George
Andrea Facciabene
Gilberto Filaci
Maddalena Mastrogiacomo

Frontiers in Oncology

doi 10.3389/fonc.2025.1572315

793 views

Review

Accepted on 21 Oct 2025

Improving Radiation Therapy Efficacy Considering DNA Repair, TP53 Mutations, Microscopic Heterogeneity and Low & High Dose Apoptosis

in Molecular and Cellular Oncology

Anders Brahme

Frontiers in Oncology

Review

Published on 21 Oct 2025

Long noncoding RNAs involved in therapeutic response: implications for cervical cancer drug resistance

in Molecular and Cellular Oncology

Samuel Trujano-Camacho
Carlos Contreras-Romero
Verónica García-Castillo
David Sánchez-Marín
Mercedes Olvera-Valencia
Mauricio Rodríguez-Dorantes
Oscar Peralta-Zaragoza
David Cantú de León
Eduardo López-Urrutia
Carlos Pérez-Plasencia

Frontiers in Oncology

doi 10.3389/fonc.2025.1644104

728 views

Editorial

Published on 09 Oct 2025

Editorial: Interplay of immunity and ECM in cancer

in Molecular and Cellular Oncology

Albina Fejza
Federica Benvenuti
Eva Andreuzzi

Frontiers in Oncology

doi 10.3389/fonc.2025.1704061

1,018 views

Review

Published on 07 Oct 2025

MicroRNAs and lung cancer: overview of essential pathways and somatic mutations in cancer progression

in Molecular and Cellular Oncology

Andrei-Alexandru Tirpe
Andreea Nutu
Constantin Busuioc
Ovidiu-Laurean Pop
Ioana Berindan-Neagoe

Frontiers in Oncology

doi 10.3389/fonc.2025.1677471

1,495 views

Mini Review

Published on 07 Oct 2025

Context-dependent rewiring of dual-function proteins in cancer: a sequential strategy to restore apoptosis

in Molecular and Cellular Oncology

Leon Strzadala

Frontiers in Oncology

doi 10.3389/fonc.2025.1675537

1,544 views

Original Research

Published on 03 Oct 2025

Next-generation sequencing-based genomic profiling of advanced soft tissue and bone sarcomas

in Molecular and Cellular Oncology

Yasemin Gündoğdu
Elif Şenocak Taşçı
Leyla Özer
Can Boynukara
Recep Çeçen
Arda Ulaş Mutlu
İbrahim Yıldız

Frontiers in Oncology

doi 10.3389/fonc.2025.1627452

1,386 views