REVIEW article

Front. Pain Res.

Sec. Cancer Pain

Volume 6 - 2025 | doi: 10.3389/fpain.2025.1601220

Insights and progress on postoperative analgesia of radical gastrectomy for gastric cancer: a comprehensive review

Provisionally accepted
Linghui  LiLinghui Li1Yuanyuan  ZhaoYuanyuan Zhao2Jianqin  ZhaoJianqin Zhao1Huan  ChenHuan Chen1Mengjun  DaiMengjun Dai1Qi  WangQi Wang1Jie  LvJie Lv1Wei  WangWei Wang1*
  • 1Nanjing Jiangning Hospital, Nanjing, Liaoning Province, China
  • 2First People's Hospital of Huainan, Huainan, Anhui Province, China

The final, formatted version of the article will be published soon.

Gastric cancer is a common and highly lethal malignancy of the digestive system, with surgical resection as the primary treatment approach. However, postoperative analgesia management remains a major clinical challenge. Postoperative pain not only affects recovery speed but may also lead to complications, thereby influencing prognosis. Recent research on postoperative pain following gastric cancer surgery has expanded, exploring various analgesic methods, including pharmacological therapy, neuraxial blocks, and non-pharmacological approaches, with growing emphasis on individualized analgesia protocols. Despite the proposal of multiple analgesic techniques, current research indicates that their effectiveness and safety are still inadequately assessed in clinical applications. This review aims to discuss the physiological mechanisms of postoperative pain following gastric cancer surgery, modern analgesic strategies, and related research, to provide a theoretical basis and clinical guidance for improving postoperative quality of life.

Keywords: Stomach Neoplasms, Analgesia, Pain Management, Pain mechanisms, clinical studies as topic

Received: 03 Apr 2025; Accepted: 17 Jun 2025.

Copyright: © 2025 Li, Zhao, Zhao, Chen, Dai, Wang, Lv and Wang. This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) or licensor are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

* Correspondence: Wei Wang, Nanjing Jiangning Hospital, Nanjing, Liaoning Province, China

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